Cheap flights from PTY to MEX (Tocumen Intl. to Mexico City Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from PTY to MEX starting at $217 One Way, $354 Round Trip

Prices starting at $354 for return flights and $217 for one-way flights to Mexico City Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near Mexico City Intl.

Airport Hotels near Mexico City Intl.

Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

4 out of 5
Mexico City
$134 nightly
The price is $160 total per night from Mar 2 to Mar 3
$160 total
Mar 2 - Mar 3
Total with taxes and fees
Book a stay at this spa hotel in Mexico City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (12,160 reviews)
Great amaenities... Pool and buffet!

Reviewed on Feb 5, 2026

Camino Real Aeropuerto Mexico
Fiesta Inn Ciudad de Mexico Aeropuerto

Fiesta Inn Ciudad de Mexico Aeropuerto

3.5 out of 5
Boulevard Puerto Aereo 502 Mexico City CDMX
$125 nightly
The price is $149 total per night from Mar 7 to Mar 8
$149 total
Mar 7 - Mar 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Mexico City. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.6/10 Excellent! (3,371 reviews)
Room was spotless and hotel was really close to the subway system and the airport

Reviewed on Feb 3, 2026

Fiesta Inn Ciudad de Mexico Aeropuerto
Hilton Mexico City Airport

Hilton Mexico City Airport

4.5 out of 5
Inside Mexico City Airport, Terminal 1 Mexico City
$185 nightly
The price is $221 total per night from Feb 28 to Mar 1
$221 total
Feb 28 - Mar 1
Total with taxes and fees
Book a stay at this luxury hotel in Mexico City. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our ...
8/10 Very Good! (1,336 reviews)
Inside the airport. Many food places just downstairs from the hotel that are open 24 hours. The room is nice and clean.

Reviewed on Feb 8, 2026

Hilton Mexico City Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Mexico City

Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

4 out of 5
Mexico City
$134 nightly
The price is $160 total per night from Mar 2 to Mar 3
$160 total
Mar 2 - Mar 3
Total with taxes and fees
Book a stay at this spa hotel in Mexico City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (12,160 reviews)
Great amaenities... Pool and buffet!

Reviewed on Feb 5, 2026

Camino Real Aeropuerto Mexico
Fiesta Americana Reforma

Fiesta Americana Reforma

4 out of 5
Paseo De La Reforma 80 Mexico City CDMX
$129 nightly
The price is $155 total per night from Mar 13 to Mar 14
$155 total
Mar 13 - Mar 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Mexico City. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (4,313 reviews)
Clean rooms. Central area. And very helpful staff

Reviewed on Feb 1, 2026

Fiesta Americana Reforma
Barceló México Reforma

Barceló México Reforma

4.5 out of 5
Paseo De La Reforma 1 Mexico City
$112 nightly
The price is $133 total per night from Mar 1 to Mar 2
$133 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this luxury hotel in Mexico City. Enjoy a full-service spa, 3 restaurants, and 3 hot tubs. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (5,197 reviews)
Exelente

Reviewed on Feb 7, 2026

Barceló México Reforma
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mexico City Hotels With Airport Transportation

Fiesta Inn Plaza Central Aeropuerto

Fiesta Inn Plaza Central Aeropuerto

3.5 out of 5
Avenida Canal Río Churubusco #1635 Mexico City CDMX
$90 nightly
The price is $108 total per night from Mar 1 to Mar 2
$108 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Mexico City. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.8/10 Excellent! (1,507 reviews)
airport shuttle, safe area, central to everything, reasonable price,

Reviewed on Jan 30, 2026

Fiesta Inn Plaza Central Aeropuerto
Hotel Riazor Aeropuerto

Hotel Riazor Aeropuerto

3.5 out of 5
Viaducto Miguel Alemán 297 Mexico City
Book a stay at this business-friendly hotel in Mexico City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
9.4/10 Exceptional! (2,390 reviews)
Always a great stay

Reviewed on Feb 5, 2026

Hotel Riazor Aeropuerto
We Hotel Aeropuerto

We Hotel Aeropuerto

3.5 out of 5
Boulevard Puerto Aereo 390 Mexico City
$94 nightly
The price is $112 total per night from Feb 11 to Feb 12
$112 total
Feb 11 - Feb 12
Total with taxes and fees
Stay at this hotel in Mexico City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.4/10 Very Good! (2,162 reviews)
Perfect for an overnight layover. Room was a bit stark. Large enough for a king bed, 2 night tables, and a desk. Nice large shower with stones that massage your feet. There was a building blocking the window, so no view. It was a little cave like, but it was just for sleeping. Gym is basic with a ...

Reviewed on Jan 21, 2026

We Hotel Aeropuerto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Mexico City Hotels

Hotel Castropol

Hotel Castropol

3 out of 5
Av. Pino Suarez, 58 Mexico City CDMX
The price is $68 total per night from Mar 11 to Mar 12
$68 total
per night
Mar 11 - Mar 12
Book a stay at this business-friendly hotel in Mexico City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the ...
8.8/10 Excellent! (1,001 reviews)
I liked restaurant breakfast, excellent customer service there. Rooms are fine.

Reviewed on Feb 5, 2026

Hotel Castropol
Hotel Sevilla

Hotel Sevilla

3 out of 5
Serapio Rendon 124 Mexico City CDMX
The price is $45 total per night from Feb 16 to Feb 17
$45 total
per night
Feb 16 - Feb 17
Stay at this hotel in Mexico City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (1,058 reviews)
The room and bathroom were clean and the staff were helpful..

Reviewed on Jan 25, 2026

Hotel Sevilla
Ayenda Frida Costa Azul

Ayenda Frida Costa Azul

3 out of 5
Fray Servando Teresa de Mier # 121 Mexico City CDMX
Stay at this hotel in Mexico City. Enjoy free parking, room service, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (1,002 reviews)
Great one night stay and only a 15 minute drive from the airport. Clean, accessible, good location.

Reviewed on Jan 23, 2026

Ayenda Frida Costa Azul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Mexico City

Courtyard Mexico City Airport

Courtyard Mexico City Airport

4 out of 5
Sinaloa 31, Penon de los Banos Mexico City
$179 nightly
The price is $214 total per night from Feb 28 to Mar 1
$214 total
Feb 28 - Mar 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Mexico City. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast ...
9.2/10 Wonderful! (1,803 reviews)
Everything ok, clean and nice

Reviewed on Feb 9, 2026

Courtyard Mexico City Airport
Holiday Inn Zona Centro by IHG

Holiday Inn Zona Centro by IHG

3.5 out of 5
Mariano Azuela No 12 Mexico City
$97 nightly
The price is $116 total per night from Mar 1 to Mar 2
$116 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Mexico City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,001 reviews)
Cleanliness of ķ

Reviewed on Feb 3, 2026

Holiday Inn Zona Centro by IHG
Hampton Inn & Suites Mexico City - Centro Historico

Hampton Inn & Suites Mexico City - Centro Historico

3 out of 5
Calle 5 de Febrero No. 24 Mexico City
$89 nightly
The price is $107 total per night from Feb 17 to Feb 18
$107 total
Feb 17 - Feb 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Mexico City. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,117 reviews)
Quiet , clean and adequate basic room in an architecturally lovely old building with a wonderful interior. Window was frosted and mirrored to block brick wall view, so room was dark. The breakfast was mediocre. Excellent location in centro easy walking to many sites.

Reviewed on Feb 6, 2026

Hampton Inn & Suites Mexico City - Centro Historico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

PTY to MEX Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
PTY Address & GPS
Address:
Panama City ,
Panama
IATA Code:
PTY
Longitude:
-79.387639
Latitude:
9.066897
Time Zone:
America/Panama
MEX Address & GPS
Address:
Mexico City ,
Mexico
IATA Code:
MEX
Longitude:
-99.072778
Latitude:
19.435278
Time Zone:
America/Mexico_City

Frequently asked questions

Are there non-stop flights from Tocumen Intl. Airport (PTY) to MEX?
Don't worry about long layovers or missing your next flight. Copa Airlines will take you directly from Tocumen Intl. Airport (PTY) to Benito Juárez Intl. Airport.
What is the shortest flight from Tocumen Intl. Airport (PTY) to Mexico Airport?
Relish in a glass of vino and get comfy in your seat with an interesting movie or book. With the journey from PTY to MEX taking 3 hours and 58 minutes, you'll have enough time to kick back and enjoy the experience.
How many hours flight from Tocumen Intl. Airport (PTY) to Benito Juárez Intl. Airport?
The journey from Panama Airport to Mexico City Intl. Airport (MEX) will take roughly 4 hours and 1 minute. A few good movies, some journaling and a bit of shut-eye will make the time zip by.
What airlines have the most flights from PTY to Mexico Airport?
Offering 178 flights per month between Panama City and Mexico City, Copa Airlines will get you to your destination safely and comfortably.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore