Beginning of main content
Round Trip Icon
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5
Due to coronavirus (COVID-19) travel advisories, some destinations may be unavailable for certain dates. Find out more.

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheapest Flights from Panama City starting at $128 One Way, $198 Round Trip

One way and return prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Flights Review

Mar 16, 2020


Mar 14, 2020

It was a great flight overall!

Mar 9, 2020


Mar 8, 2020

The layover was to long.

Feb 28, 2020

this was my first flight with COPA airlines, i was thankful that i got upgraded since the system was unable to give me a second boarding pass for my second leg. the first leg appeared to be longer and although i had an aisle seat, those seats were hard and i was very uncomfortable. also since i booked last minute i could not check in online and request vegetarian option but i am thankful that the leg back to orlando was very comfortable and the flight attendant was very professional especially since she had be bilingual

Feb 21, 2020

Highly recommended

Jan 31, 2020

Even got a small snack for an hour long flight.

Jan 30, 2020

Smooth flight. Helpful friendly staff. Well organized.

Jan 30, 2020

Loved the flight!

Jan 29, 2020

Short flight and still got a snack and drink included, they spoke english to me without me even asking. Very nice staff!

Jan 29, 2020

Simple. This Airlines os amazing

Jan 22, 2020

I will recommend this airline. Good meal with two glasses of wine (albeit small ones). So easy to check in. Direct flight to Panama. On-time departure and early arrivals. Nothing in US compares

Flights from Panama City: All You Need to Know

What's the cheapest flight from Panama City?$198 (roundtrip)
What airlines fly from Panama City?Copa, Spirit Airlines, Hahn Air Technologies, Avianca, American Airlines
What is the best month to fly from Panama City?September
What is Panama City IATA code?PTY
What country/state is Panama City in?Panama
How much is a flight from Panama City?$198 - $285


Flights from Panama City

Miles? Yes. Window? Yes. Cheap flights from Panama City on Orbitz? Yes.
  • Add your frequent flier number when you book a cheap flight from Panama City on Orbitz, and accumulate miles on applicable flights.
  • Choose your seats on flights from Panama City — aisle or window, front or back.
  • Get airfare alerts for flights from Panama City. Set your target price, destination, and travel dates, and we'll send you an alert if we find cheap flights from Panama City that meet or beat your target price. Orbitz Deals E-mail can help you catch discount flights from Panama City, too.
An entire support team for your flights from Panama City

When you book your cheap flights from Panama City on Orbitz, you get free, real-time trip updates sent to your mobile phone about delays and other events that could impact your travel. Choose to have your alerts sent to up to six others, such as the person picking you up from the airport in Panama City when you return.

Need to change your cheap flights from Panama City?

You don't have to call to change your flights from Panama City. You can do that yourself online. We'll let you know if there's part of your airfare that can be put toward a future flight from Panama City. Travel should be a pleasure, so that's why we strive to get you the best deal on cheap flights from Panama City and deliver the support you deserve.


Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.