$125 Cheap flights to Panama

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Top places to visit in Panama

Cheap flights to Panama from $125 One Way, $258 Round Trip

$258 return flights and $125 one-way flights to Panama were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

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Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
SJOTocumenApril 10 to April 17$275
MIATocumenApril 10 to April 12$400
MEXTocumenApril 12 to April 16$476
CCSTocumenApril 12 to April 24$492
JFKTocumenApril 11 to April 21$543
JFKTocumenApril 11 to April 21$543
FLLTocumenApril 11 to April 13$550
LAXTocumenApril 12 to April 16$690
ATLTocumenApril 12 to April 14$961
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic Panama Accommodation Deals

Metro Hotel Panama

Metro Hotel Panama

3.5 out of 5
Via Veneto, Calle D El Cangrejo Panama City Panama
Fully refundableReserve now, pay when you stay
The price is $64 total per night from May 7 to May 8
$64 total
per night
May 7 - May 8
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Albrook Shopping Mall ...
Opens in a new windowMetro Hotel Panama
Hotel Centroamericano

Hotel Centroamericano

3 out of 5
Avenida Ecuador y Justo Arosemena Panama City Panama
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Albrook Shopping Mall ...
Opens in a new windowHotel Centroamericano
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

3.5 out of 5
Calle 53 Marbella y Avenida 5a B sur Panama City Panama
Fully refundable
The price is $56 total per night from Apr 9 to Apr 10
$56 total
per night
Apr 9 - Apr 10
Stay at this hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the overall value in our ...
7.4/10 Good! (810 reviews)
I will start with the positives. The staff is amazing! Super nice and polite and will help you and answer any questions you have. The price for the hotel is also amazing. The AC worked amazingly and we had it at the lowest temperature all 5 days we were there. The property on the other hand is nothing ...

Reviewed on Apr 4, 2026

Opens in a new windowHospedium Princess Hotel Panama
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Hotel Coral Suites

Hotel Coral Suites

3.5 out of 5
Calle D El Cangrejo Panama City Panama
Fully refundableReserve now, pay when you stay
The price is $76 total per night from May 2 to May 3
$76 total
per night
May 2 - May 3
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,005 reviews)
Room was ok just dated. Pillows were flat. There was mold in the showers. They did not provide washcloths and barely wanted to provide face cloths. If its only a 2 or 3 day trip its doable but if longer just go somewhere else

Reviewed on Apr 4, 2026

Opens in a new windowHotel Coral Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top Panama Apartment Hotels

Hotel Coral Suites

Hotel Coral Suites

3.5 out of 5
Calle D El Cangrejo Panama City Panama
Fully refundableReserve now, pay when you stay
The price is $76 total per night from May 2 to May 3
$76 total
per night
May 2 - May 3
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,005 reviews)
Room was ok just dated. Pillows were flat. There was mold in the showers. They did not provide washcloths and barely wanted to provide face cloths. If its only a 2 or 3 day trip its doable but if longer just go somewhere else

Reviewed on Apr 4, 2026

Opens in a new windowHotel Coral Suites
Tropical Suites Hotel

Tropical Suites Hotel

3.5 out of 5
First Street, Bocas Town Bocas del Toro
The price is $168 total per night from May 4 to May 5
$168 total
per night
May 4 - May 5
Book a stay at this business-friendly hotel in Bocas del Toro. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Bolivar Park and ...
9.2/10 Wonderful! (309 reviews)
Kitchen was sparse. No coffee maker only espresso machine. We enjoyed our stay. Slept great. Papaya restaurant nearby was our favorite. Staff in Merlin restaurant below the hotel was always friendly and greeted us with a wave and smile but never came over to take our order so on three different occasions ...

Reviewed on Mar 22, 2026

Opens in a new windowTropical Suites Hotel
Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites

3.5 out of 5
Calle Eusebio A. Morales y Calle 55 Panama City Panama
Fully refundableReserve now, pay when you stay
The price is $102 total per night from Apr 13 to Apr 14
$102 total
per night
Apr 13 - Apr 14
Book a stay at this business-friendly aparthotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
8.8/10 Excellent! (538 reviews)
Simply The Best!!!

Reviewed on Apr 4, 2026

Opens in a new windowTorres de Alba Hotel & Suites
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Aparthotel Sevilla Suites

Aparthotel Sevilla Suites

3 out of 5
Ave. Eusebio A Morales Panama City
Book a stay at this business-friendly aparthotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition ...
8.8/10 Excellent! (44 reviews)
My stay was cut short due to requirements to leave 1 week earlier because of closure to the airport. Management very understanding, and made refund immediately due to the unforeseen circumstances.......Overall my stay was pleasant.

Reviewed on Mar 31, 2020

Opens in a new windowAparthotel Sevilla Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic Panama Accommodation Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is $135 total per night from May 5 to May 6
$135 total
per night
May 5 - May 6
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (5,234 reviews)
Most amazing breakfast ever

Reviewed on Apr 7, 2026

Opens in a new windowHotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
The price is $151 total per night from Apr 28 to Apr 29
$151 total
per night
Apr 28 - Apr 29
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (2,497 reviews)
Sheets like rubberised tarp, no fridge, pool closed, 9$ water, dirty bathroom peeling door, awful buffet food

Reviewed on Apr 5, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
The price is $139 total per night from May 3 to May 4
$139 total
per night
May 3 - May 4
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,001 reviews)
Excellent

Reviewed on Apr 7, 2026

Opens in a new windowSheraton Grand Panama
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Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
The price is $125 total per night from Apr 12 to Apr 13
$125 total
per night
Apr 12 - Apr 13
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (1,006 reviews)
First of alll this hotel is under rated this is near 5 star , just a few minor touch up and get rid of the moist smell nd it’s perfect

Reviewed on Apr 7, 2026

Opens in a new windowHotel El Panama by Faranda Grand, a member of Radisson Individuals
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Panama

The Westin Playa Bonita Panama
Great for families

The Westin Playa Bonita Panama

5 out of 5
Km 6 Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
The price is $222 total per night from May 1 to May 2
$222 total
per night
May 1 - May 2
Book a stay at this luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8/10 Very Good! (1,013 reviews)

Families like: Outdoor pools, kids club, playground, babysitting

Travelers say...
The property was really nice for the most part. There were a few areas that might need to be fixed soon but nothing major. The pools were great. Staff was great. Didn't have any problems with parking. Lots of great activities for the kids to do. Would stay again. One thing I wasn"t aware of was low ...

Reviewed on Apr 7, 2026

Opens in a new windowThe Westin Playa Bonita Panama
TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro

3.5 out of 5
Via Veneto, El Cangrejo Bellavista Panama City Panama
The price is $108 total per night from Apr 22 to Apr 23
$108 total
per night
Apr 22 - Apr 23
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,007 reviews)
I’ve recommended this hotel several times, great experience each time!

Reviewed on Apr 7, 2026

Opens in a new windowTRYP by Wyndham Panamá Centro
Gran Evenia Bijao - All Inclusive
Great for families

Gran Evenia Bijao - All Inclusive

4.5 out of 5
Carretera Interamericana km 108, guias de Anton Rio Hato Coclé
Book a stay at this luxury hotel in Rio Hato. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Playa Blanca and Santa Clara Beach are located ...
7.4/10 Good! (1,000 reviews)

Families like: Outdoor pools, free waterpark access, kids club, playground

Travelers say...
Receptionist was very serious, employees should look happy as they are enjoying their job.

Reviewed on Mar 8, 2026

Opens in a new windowGran Evenia Bijao - All Inclusive
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Hotel Riu Playa Blanca - All Inclusive
Great for families

Hotel Riu Playa Blanca - All Inclusive

3.5 out of 5
Finca 43.668 Rio Hato Cocle
Book a stay at this beach property in Rio Hato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8/10 Very Good! (1,005 reviews)

Families like: Outdoor pools, waterslide, playground, on the beach

Travelers say...
Great stay, the food excellent

Reviewed on Apr 7, 2026

Opens in a new windowHotel Riu Playa Blanca - All Inclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Panama

Struggling to find international and domestic flights that suit your budget. Consider one of the cheaper options available when you book your flight with Orbitz, where you get guaranteed low prices

Orbitz becomes your Mobile friend

You can now book flights to Panama on the new cutting-edge mobile tool for Android or iPhone users. Hotel packages, flight updates and changes can all be accessed using this tool. When you make any reservations or bookings using this service, confirmation will be provided on the same day the request was made. Take advantage of Orbitz friendly service and low cost Panama flights.

Discounted tickets available for flights to Panama

Orbitz offers tickets at a discounted, budget friendly rate that will satisfy all of your travel requirements. Book your Panama flights with us and structure a package that includes car hire, family activities and cheap accommodation. Orbitz will ensure that all your requirements are met, letting you relax and enjoy your holiday as it was intended.

Orbitz offers discounted Panama flights

Discounted flights to Panama ensure that all who want to travel can Take advantage of Orbitz’ guaranteed low prices and affordable packages. You will enjoy a hassle free trip, an up to date travel planner and friendly service.

Traveler profile updates

When flying with Orbitz, take advantage of frequent updates on your flights to Panama. Details and updates are sent to up to six contact numbers to ensure that you are kept abreast of the latest information on Panama flights. Frequent flyer and loyalty membership numbers may be updated within your Orbitz account profile.

Frequently asked questions

Which airlines fly to Panama?
With 12 airlines waiting to whisk you away to Panama, finding an ideal flight will be a breeze. Book a ticket with one of these top international carriers that operate services to Tocumen Intl. Airport (PTY):

  • Copa Airlines - 2,281 flights to Panama per month
  • United Airlines - 52 flights to Panama per month
  • American Airlines - 33 flights to Panama per month

How much is a flight to Panama?
Lots of fantastic deals were up for the taking this week, with return flights to Panama ranging between $258 and $961. But it was jet-setters starting their trip from San José (SJO) who scored the best bargains. One-way flights to Panama fell to just $125.
How to book the cheapest flight to Panama?
With Orbitz, you'll find some of the most amazing flight deals around from a big selection of airlines. But if you'd like to heighten your chances of nabbing cheap flights to Panama, here are a few pointers we think will help:

  • Consider taking off from or landing at alternative airports for a better deal. Enter your preferred departure and arrival points in the form fields, then click on the 'Nearby airports' function below. It will list the available options.
  • If you're flexible with your itinerary, click on the 'Show flexible dates' link. It'll show the flight deals for the days around your chosen departure. Airfares often vary depending on what day of the week it is.
  • To filter your results, hit 'Show options.' You can search based on seating class, airlines, and nonstop and refundable flights. You can also select your preferred departure and arrival times under 'Sort & Filter' to the left.
  • The early bird gets the most impressive deals, so book as soon as you've worked out your travel dates. The cheapest fares go like hotcakes and prices generally climb as the departure date nears.
  • Consider bundling your flights, hotels and car rental into an Orbitz package deal — the more you book, the more you save.
  • Flying during the busy season means pricey airfares. Try to travel outside of popular dates, such as Thanksgiving, New Year's Eve and Easter.

What is the best time to book a flight to Panama?
Generally speaking, January is the ideal time to book your plane ticket. This is followed by February and August. Keep this in mind while searching for a cheap flight to Panama.
What day of the week is the cheapest to book a flight to Panama?
Land a fantastic flight deal by booking on a Tuesday, Wednesday or Saturday. These are typically the best days to pick up cheap airfares to Panama.
What is the cheapest day of the week to fly to Panama?
You can pick up cheap flights to Panama by flying out on a Monday, according to Orbitz data from 2020. Tuesday is the next cheapest day, while Saturday has the most costly airfares. Whether you prefer to stretch your travel budget or take off on any day that's convenient, you'll always find a fantastic deal with Orbitz.
What is the cheapest month to fly to Panama?
Consider traveling during August if you don't want to eat into your budget. Orbitz data has found that it's generally the best month for cheap flights to Panama. June is when ticket prices are at their highest.
Which airlines allow free cancellation?
When searching for your Panama flights on Orbitz, choose "Filter by flexible change policies." This filter will show you all the carriers offering free cancellation within 24 hours of booking and no change fees. That means you can breathe easy knowing that if things change, your ticket can too.
What do I need for the flight to Panama?
There's so much to sort out for any big trip, so it's useful to get a bit of help along the way. Here are a few suggestions to ensure you're ready for your flight:

  • Firstly, you'll need to take all applicable travel documents and identification. How much depends on your place of departure. When booking, you're encouraged to use the correct name, gender and birth date listed on your current ID.
  • Fill your carry-on bag with snacks and activities and watch time whiz by on this medium-haul flight. If you can, get on the airport's Wi-Fi and save your favorite playlist or podcast to your phone or tablet before take off.
  • Never mind what the season is at your destination, plane cabins are known to get chilly. Bring an extra layer on your journey to stay warm and comfy.

How do I get cheap first-class/business deals to Panama?
Savvy travelers have a talent for finding business or first-class fares to Panama without the eye-watering price tag. Take their lead with these helpful tips:

  • Be more flexible with your travel dates and hold out for sales or exclusive offers on business or first-class airfares.
  • Low-cost airlines offer business-class seats at affordable prices. Ditch the full-service carriers and go with one of these cheaper options.
  • Take advantage of your airline's flight rewards program and use points to upgrade your seat. Alternatively, you can try bidding for an upgrade in online auctions.

What is the best time to go to Panama?
Travelers come from all over to visit Panama in February, March and May. So if you want to experience this fabulous destination in the busy season, this is the best time to go. Like many places in the Northern Hemisphere, the summer begins June 20 in Panama, with average daily temperatures ranging between 80 ºF and 85 ºF.
Travel tips for Panama

  • The possibilities for adventure in Panama are almost endless — and Xcaret Eco Theme Park is just one place you'll find it. Grab a car rental, find out how to get to this fabulous attraction and then get cruisin'!
  • One of Panama's most prominent cities, Panama City is the ideal place to start an epic road trip around this region. Eat, sleep, explore and repeat — it's what getaways are for!

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.