$221 Cheap flights to Panama

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Many airlines offer flexible change policies

Top places to visit in Panama

A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City

Cheap flights to Panama from $221 One Way, $264 Round Trip

$264 return flights and $221 one-way flights to Panama were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Sep 2 - Sat, Sep 5

MIA

Miami

PTY

Panama City

$392

Roundtrip

found 22 hours ago

Sun, Nov 1 - Thu, Nov 5

JFK

New York

PTY

Panama City

$410

Roundtrip

found 2 hours ago

Sun, Nov 1 - Thu, Nov 5

JFK

New York

PTY

Panama City

$412

Roundtrip

found 2 hours ago

Sun, Nov 1 - Thu, Nov 5

JFK

New York

PTY

Panama City

$413

Roundtrip

found 2 hours ago

Thu, Dec 3 - Thu, Dec 10

YYZ

Toronto

RIH

Rio Hato

$451

Roundtrip

found 1 day ago

Mon, Mar 1 - Wed, Mar 10

MIA

Miami

DAV

David

$472

Roundtrip

found 10 hours ago

Thu, Feb 25 - Thu, Mar 25

YYZ

Toronto

RIH

Rio Hato

$487

Roundtrip

found 3 days ago

Thu, Oct 29 - Wed, Nov 4

IAD

Washington

PTY

Panama City

$498

Roundtrip

found 6 hours ago

Thu, Dec 3 - Thu, Dec 10

YYZ

Toronto

RIH

Rio Hato

$515

Roundtrip

found 1 day ago

Thu, Dec 3 - Thu, Dec 10

YYZ

Toronto

RIH

Rio Hato

$530

Roundtrip

found 1 day ago

Thu, Oct 29 - Wed, Nov 4

YYZ

Toronto

PTY

Panama City

$533

Roundtrip

found 4 days ago

Thu, Mar 18 - Fri, Mar 19

YYZ

Toronto

RIH

Rio Hato

$551

Roundtrip

found 4 days ago

Deals For This Weekend's Flights

Origin	Destination	Travel Dates	Flights From*
SJO	Tocumen	September 5 to September 7	$264
MIA	Tocumen	September 4 to September 8	$510
MEX	Tocumen	September 4 to September 11	$582
LAX	Tocumen	September 6 to September 22	$621
FLL	Tocumen	September 4 to September 7	$628
ATL	Tocumen	September 6 to September 10	$742
JFK	Tocumen	September 6 to September 13	$770
FCO	Tocumen	September 4 to September 7	$1,198

*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic Panama Accommodation Deals

Metro Hotel Panama

Via Veneto, Calle D El Cangrejo Panama City Panama

Fully refundable

$69 nightly

$76 total

Sep 15 - Sep 16

Total with taxes and fees

Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Albrook Shopping Mall ...

Hotel Centroamericano

Avenida Ecuador y Justo Arosemena Panama City Panama

Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Albrook Shopping Mall ...

Get rates

Hospedium Princess Hotel Panama

Calle 53 Marbella y Avenida 5a B sur Panama City Panama

Fully refundable

$44 nightly

$49 total

Sep 27 - Sep 28

Total with taxes and fees

Stay at this hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the overall value in our ...

7.2/10 Good! (965 reviews)

"el trato de los empleados fue excelente , la limpieza buena,lo único no había agua caliente, el aire acondicionado casi no enfriaba en el cuarto, en el área del comedor fue horrible la calor ,los desayunos no eran variables muy poco a escoger , le faltan muchos detalles para darle un 200 de 100"

Reviewed on Aug 28, 2026

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Hotel Coral Suites

Calle D El Cangrejo Panama City Panama

Fully refundableReserve now, pay when you stay

$70 nightly

$77 total

Sep 27 - Sep 28

Total with taxes and fees

Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the ...

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top Panama Apartment Hotels

Hotel Coral Suites

Calle D El Cangrejo Panama City Panama

Fully refundableReserve now, pay when you stay

$70 nightly

$77 total

Sep 27 - Sep 28

Total with taxes and fees

Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the ...

Tropical Suites Hotel

First Street, Bocas Town Bocas del Toro

Fully refundableReserve now, pay when you stay

$124 nightly

$139 total

Sep 29 - Sep 30

Total with taxes and fees

Book a stay at this business-friendly hotel in Bocas del Toro. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Bolivar Park and ...

9.2/10 Wonderful! (330 reviews)

"would not stay again"

Reviewed on Aug 28, 2026

Torres de Alba Hotel & Suites

Calle Eusebio A. Morales y Calle 55 Panama City Panama

Fully refundableReserve now, pay when you stay

$92 nightly

$102 total

Aug 30 - Aug 31

Total with taxes and fees

Book a stay at this business-friendly aparthotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...

8.8/10 Excellent! (576 reviews)

"Staff was nice and helpful, breakfast was consistent each morning, fresh fruits daily and omelettes made on request, the room could use more modernization and attention but it was okay. Would recommend for budget trips. Also a very central location for walking to restaurants, getting essentials at ..."

Reviewed on Aug 25, 2026

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Aparthotel Sevilla Suites

Ave. Eusebio A Morales Panama City

Book a stay at this business-friendly aparthotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition ...

8.8/10 Excellent! (44 reviews)

"My stay was cut short due to requirements to leave 1 week earlier because of closure to the airport. Management very understanding, and made refund immediately due to the unforeseen circumstances.......Overall my stay was pleasant."

Reviewed on Mar 31, 2020

Get rates

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic Panama Accommodation Deals

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

Fully refundableReserve now, pay when you stay

$132 nightly

$145 total

Sep 28 - Sep 29

Total with taxes and fees

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...

9/10 Wonderful! (5,865 reviews)

"The breakfast was excellent and the staff was great. All in all, the hotel is an A+"

Reviewed on Aug 29, 2026

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama

Fully refundable

$128 nightly

$141 total

Sep 26 - Sep 27

Total with taxes and fees

Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...

8.6/10 Excellent! (2,685 reviews)

"Staff was friendly."

Reviewed on Aug 29, 2026

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama

Fully refundableReserve now, pay when you stay

$183 nightly

$202 total

Sep 27 - Sep 28

Total with taxes and fees

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...

9.2/10 Wonderful! (1,007 reviews)

"Don’t expect to sleep Upon checkin I was out in my “Jr Suite”. It was just a room. But worse, I tried to soon and heard a rhythmic banging that was impossible to sleep through. It was so bad that I decided to see what it was. My room was DIRECTLY UNDER the gym, in a centuries old building?! If anyone ..."

Reviewed on Aug 29, 2026

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Gran Evenia Bijao - All Inclusive

Carretera Interamericana km 108, guias de Anton Rio Hato Coclé

$192 nightly

$213 total

Sep 28 - Sep 29

Total with taxes and fees

Book a stay at this beach hotel in Rio Hato. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Panama

The Westin Playa Bonita Panama

Km 6 Road to Veracruz Veracruz Panama

$197 nightly

$217 total

Sep 25 - Sep 26

Total with taxes and fees

Book a stay at this luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...

8.2/10 Very Good! (1,001 reviews)

Families like: Outdoor pools, kids club, playground, babysitting

Travelers say...

"Vacation in Panama with a 3 day stay it was wonderful the gym we were also very impressed with and our morning walks on the beach"

Reviewed on Aug 26, 2026

TRYP by Wyndham Panamá Centro

Via Veneto, El Cangrejo Bellavista Panama City Panama

Fully refundableReserve now, pay when you stay

$93 nightly

$102 total

Sep 28 - Sep 29

Total with taxes and fees

Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the ...

Hotel Riu Playa Blanca - All Inclusive

Finca 43.668 Rio Hato Cocle

Book a stay at this golf property in Rio Hato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...

Families like: Outdoor pools, waterslide, playground, close to beach

Get rates

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Dreams Playa Bonita Panama - All Inclusive

KM 7, Road to Veracruz Veracruz Panama

Fully refundableReserve now, pay when you stay

$272 nightly

$272 total

Aug 30 - Aug 31

Total with taxes and fees

Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...

7.8/10 Good! (1,066 reviews)

Families like: Outdoor pools, kids club, playground, miniature golf

Travelers say...

"A Beautiful and Memorable Stay My wife and I had the pleasure of spending an entire week at this beautiful hotel, and our experience was truly memorable from beginning to end. What stood out to us most was the exceptional customer service. Every member of staff we encountered was incredibly polite, ..."

Reviewed on Aug 29, 2026

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark

4 people

Compact

Ford Focus

4 people

Midsize

Toyota Corolla

5 people

SUV

Jeep Compass

5 people

Panama

Struggling to find international and domestic flights that suit your budget. Consider one of the cheaper options available when you book your flight with Orbitz, where you get guaranteed low prices

Orbitz becomes your Mobile friend

You can now book flights to Panama on the new cutting-edge mobile tool for Android or iPhone users. Hotel packages, flight updates and changes can all be accessed using this tool. When you make any reservations or bookings using this service, confirmation will be provided on the same day the request was made. Take advantage of Orbitz friendly service and low cost Panama flights.

Discounted tickets available for flights to Panama

Orbitz offers tickets at a discounted, budget friendly rate that will satisfy all of your travel requirements. Book your Panama flights with us and structure a package that includes car hire, family activities and cheap accommodation. Orbitz will ensure that all your requirements are met, letting you relax and enjoy your holiday as it was intended.

Orbitz offers discounted Panama flights

Discounted flights to Panama ensure that all who want to travel can Take advantage of Orbitz’ guaranteed low prices and affordable packages. You will enjoy a hassle free trip, an up to date travel planner and friendly service.

Traveler profile updates

When flying with Orbitz, take advantage of frequent updates on your flights to Panama. Details and updates are sent to up to six contact numbers to ensure that you are kept abreast of the latest information on Panama flights. Frequent flyer and loyalty membership numbers may be updated within your Orbitz account profile.

Frequently asked questions

Which airlines fly to Panama?

With 24 airlines waiting to whisk you away to Panama, finding an ideal flight will be a breeze. Book a ticket with one of these top international carriers that operate services to Tocumen Intl. Airport (PTY):

Copa Airlines - 2,281 flights to Panama per month
United Airlines - 52 flights to Panama per month
American Airlines - 33 flights to Panama per month

How much is a flight to Panama?

Lots of fantastic deals were up for the taking this week, with return flights to Panama ranging between $264 and $1,198. But it was jet-setters starting their trip from Miami (MIA) who scored the best bargains. One-way flights to Panama fell to just $221.

How to book the cheapest flight to Panama?

With Orbitz, you'll find some of the most amazing flight deals around from a big selection of airlines. But if you'd like to heighten your chances of nabbing cheap flights to Panama, here are a few pointers we think will help:

Consider taking off from or landing at alternative airports for a better deal. Enter your preferred departure and arrival points in the form fields, then click on the 'Nearby airports' function below. It will list the available options.
If you're flexible with your itinerary, click on the 'Show flexible dates' link. It'll show the flight deals for the days around your chosen departure. Airfares often vary depending on what day of the week it is.
To filter your results, hit 'Show options.' You can search based on seating class, airlines, and nonstop and refundable flights. You can also select your preferred departure and arrival times under 'Sort & Filter' to the left.
The early bird gets the most impressive deals, so book as soon as you've worked out your travel dates. The cheapest fares go like hotcakes and prices generally climb as the departure date nears.
Consider bundling your flights, hotels and car rental into an Orbitz package deal — the more you book, the more you save.
Flying during the busy season means pricey airfares. Try to travel outside of popular dates, such as Thanksgiving, New Year's Eve and Easter.

What is the best time to book a flight to Panama?

Generally speaking, January is the ideal time to book your plane ticket. This is followed by February and August. Keep this in mind while searching for a cheap flight to Panama.

What day of the week is the cheapest to book a flight to Panama?

Land a fantastic flight deal by booking on a Tuesday, Wednesday or Saturday. These are typically the best days to pick up cheap airfares to Panama.

What is the cheapest day of the week to fly to Panama?

You can pick up cheap flights to Panama by flying out on a Monday, according to Orbitz data from 2020. Tuesday is the next cheapest day, while Saturday has the most costly airfares. Whether you prefer to stretch your travel budget or take off on any day that's convenient, you'll always find a fantastic deal with Orbitz.

What is the cheapest month to fly to Panama?

Consider traveling during August if you don't want to eat into your budget. Orbitz data has found that it's generally the best month for cheap flights to Panama. June is when ticket prices are at their highest.

Which airlines allow free cancellation?

When searching for your Panama flights on Orbitz, choose "Filter by flexible change policies." This filter will show you all the carriers offering free cancellation within 24 hours of booking and no change fees. That means you can breathe easy knowing that if things change, your ticket can too.

What do I need for the flight to Panama?

There's so much to sort out for any big trip, so it's useful to get a bit of help along the way. Here are a few suggestions to ensure you're ready for your flight:

Firstly, you'll need to take all applicable travel documents and identification. How much depends on your place of departure. When booking, you're encouraged to use the correct name, gender and birth date listed on your current ID.
Fill your carry-on bag with snacks and activities and watch time whiz by on this medium-haul flight. If you can, get on the airport's Wi-Fi and save your favorite playlist or podcast to your phone or tablet before take off.
Never mind what the season is at your destination, plane cabins are known to get chilly. Bring an extra layer on your journey to stay warm and comfy.

How do I get cheap first-class/business deals to Panama?

Savvy travelers have a talent for finding business or first-class fares to Panama without the eye-watering price tag. Take their lead with these helpful tips:

Be more flexible with your travel dates and hold out for sales or exclusive offers on business or first-class airfares.
Low-cost airlines offer business-class seats at affordable prices. Ditch the full-service carriers and go with one of these cheaper options.
Take advantage of your airline's flight rewards program and use points to upgrade your seat. Alternatively, you can try bidding for an upgrade in online auctions.

What is the best time to go to Panama?

Travelers come from all over to visit Panama in February, March and May. So if you want to experience this fabulous destination in the busy season, this is the best time to go. Like many places in the Northern Hemisphere, the summer begins June 20 in Panama, with average daily temperatures ranging between 80 ºF and 85 ºF.

Travel tips for Panama

The possibilities for adventure in Panama are almost endless — and Xcaret Eco Theme Park is just one place you'll find it. Grab a car rental, find out how to get to this fabulous attraction and then get cruisin'!
One of Panama's most prominent cities, Panama City is the ideal place to start an epic road trip around this region. Eat, sleep, explore and repeat — it's what getaways are for!

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

$221 Cheap flights to Panama

Top places to visit in Panama

Panama City

Cheap flights to Panama from $221 One Way, $264 Round Trip

Deals For This Weekend's Flights

Find The Perfect Hotel For After Your Flight

Score Epic Panama Accommodation Deals

Metro Hotel Panama

Hotel Centroamericano

Hospedium Princess Hotel Panama

Hotel Coral Suites

Our Top Panama Apartment Hotels

Hotel Coral Suites

Tropical Suites Hotel

Torres de Alba Hotel & Suites

Aparthotel Sevilla Suites

Score Epic Panama Accommodation Deals

Hotel Riu Plaza Panama

Crowne Plaza Panama Airport by IHG

Central Hotel Panama Casco Viejo

Gran Evenia Bijao - All Inclusive

Family Friendly Hotels in Panama

The Westin Playa Bonita Panama

TRYP by Wyndham Panamá Centro

Hotel Riu Playa Blanca - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

Need a Car For After Your Flight?

Economy

Compact

Midsize

SUV

Panama

Orbitz becomes your Mobile friend

Discounted tickets available for flights to Panama

Orbitz offers discounted Panama flights

Traveler profile updates

Frequently asked questions

Rewards are waiting for you in the Orbitz app