$221 Cheap flights to Panama
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Top places to visit in Panama
Cheap flights to Panama from $221 One Way, $264 Round Trip
$264 return flights and $221 one-way flights to Panama were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Deals For This Weekend's Flights
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| SJO | Tocumen | September 5 to September 7 | $264 |
| MIA | Tocumen | September 4 to September 8 | $510 |
| MEX | Tocumen | September 5 to September 12 | $572 |
| FLL | Tocumen | September 5 to September 9 | $628 |
| ATL | Tocumen | September 6 to October 12 | $636 |
| LAX | Tocumen | September 6 to September 13 | $700 |
| JFK | Tocumen | September 4 to September 21 | $796 |
| FCO | Tocumen | September 4 to September 7 | $1,205 |
| CCS | Tocumen | September 4 to September 9 | $1,875 |
Find The Perfect Hotel For After Your Flight
Score Epic Panama Accommodation Deals
Metro Hotel Panama
Hotel Centroamericano
Hospedium Princess Hotel Panama
"El personal fue increíblemente atento y amable. Las facilidades estaban limpias pero le hace falta un cariñito, debe ser remodelado. El aire acondicionado no enfría mucho y el agua caliente no estaba funcionando. La comida, excelente!"
Reviewed on Aug 31, 2026
Hotel Coral Suites
"The staff was friendly and courteous. The rooms were clean. The entire hotel was kept in an orderly fashion. Also enjoyed having a kitchenette in the room."
Reviewed on Aug 30, 2026
Our Top Panama Apartment Hotels
Hotel Coral Suites
"The staff was friendly and courteous. The rooms were clean. The entire hotel was kept in an orderly fashion. Also enjoyed having a kitchenette in the room."
Reviewed on Aug 30, 2026
Tropical Suites Hotel
"would not stay again"
Reviewed on Aug 28, 2026
Torres de Alba Hotel & Suites
"Staff was nice and helpful, breakfast was consistent each morning, fresh fruits daily and omelettes made on request, the room could use more modernization and attention but it was okay. Would recommend for budget trips. Also a very central location for walking to restaurants, getting essentials at ..."
Reviewed on Aug 25, 2026
Aparthotel Sevilla Suites
"My stay was cut short due to requirements to leave 1 week earlier because of closure to the airport. Management very understanding, and made refund immediately due to the unforeseen circumstances.......Overall my stay was pleasant."
Reviewed on Mar 31, 2020
Score Epic Panama Accommodation Deals
Hotel Riu Plaza Panama
"The staff at the pool area was great."
Reviewed on Sep 1, 2026
Central Hotel Panama Casco Viejo
"The hotel is in a really good location, is fairly clean, the breakfast buffet is really nice and the rooms are fairly clean and comfortable. However; I felt a bit disappointed that the hotel management wants to just focus on making money. I stayed here for a entire week and I told them that on my ..."
Reviewed on Sep 1, 2026
Crowne Plaza Panama Airport by IHG
"Manager wasn’t professional she was rude."
Reviewed on Aug 31, 2026
Dreams Playa Bonita Panama - All Inclusive
Family Friendly Hotels in Panama
The Westin Playa Bonita Panama
TRYP by Wyndham Panamá Centro
"Had to pay for breakfast after I thought it was included in my booking"
Reviewed on Aug 30, 2026
Hotel Riu Playa Blanca - All Inclusive
Families like: Outdoor pools, waterslide, playground, close to beach
"Black dirty beach with some horses leaving their excrements on the sand I will not stay there again. Expensive"
Reviewed on Aug 30, 2026
Dreams Playa Bonita Panama - All Inclusive
Need a Car For After Your Flight?
Economy
Compact
Midsize
SUV
Panama
If you are looking for affordable flights to Panama, look no further. Orbitz offers discounted rates to many destinations.
Bargain flights to Panama now available
As you review your budget and travel plans, consider the low fares Orbitz offers on Panama flights. With Orbitz, booking flights to Panama is easy and the lowest prices are guaranteed.
Easy self-help service offered
Orbitz offers cutting edge mobile tools that allow you to review and make bookings from your Android or iPhone mobile device with a simple application. You can easily and conveniently update your information or book your trip using this service. You are also able to obtain information on affordable hotel packages and receive frequent flight updates. You will receive confirmation of bookings or reservations made using the mobile service on the same day of the request. Change details or receive updates on your Panama flights by visiting the Orbitz site or mobile application.
Orbitz looks after you
Orbitz ensures that you are kept informed with up-to-date flight information, providing feedback to up to six contact numbers to ensure that everyone receives the feedback. In addition to providing the discounted deals on Panama flights, Orbitz is also able to structure a package based on your needs for activities, car hire and accommodations.
Traveler profile updates
After booking your Panama flights, you may access your account profile on the Orbitz site and update your frequent flyer or loyalty membership details. This information will remain on the system and will be available for you to access when you make any future bookings with Orbitz.
Frequently asked questions
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.
