$125 Cheap flights to Panama

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Many airlines offer flexible change policies

Top places to visit in Panama

Panama City

Cheap flights to Panama from $125 One Way, $258 Round Trip

$258 return flights and $125 one-way flights to Panama were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, May 8 - Sun, May 10

SJO

San José

PTY

Panama City

$258

Roundtrip

found 6 days ago

Tue, May 19 - Wed, May 20

SJO

San José

PTY

Panama City

$281

Roundtrip

found 12 hours ago

Fri, Aug 14 - Sun, Aug 23

MIA

Miami

PTY

Panama City

$352

Roundtrip

found 4 hours ago

Tue, Sep 15 - Fri, Sep 25

MIA

Miami

PTY

Panama City

$352

Roundtrip

found 10 hours ago

Sun, Jan 10 - Thu, Jan 14

MIA

Miami

PTY

Panama City

$387

Roundtrip

found 6 days ago

Wed, Apr 22 - Fri, Apr 24

JFK

New York

PTY

Panama City

$406

Roundtrip

found 5 days ago

Thu, Aug 6 - Fri, Aug 14

CLE

Cleveland

PTY

Panama City

$591

Roundtrip

found 5 days ago

Thu, Aug 6 - Fri, Aug 14

CLE

Cleveland

PTY

Panama City

$595

Roundtrip

found 5 days ago

Sat, Oct 3 - Sat, Oct 10

DTW

Detroit

PTY

Panama City

$636

Roundtrip

found 1 day ago

Sat, Sep 12 - Fri, Sep 18

CLE

Cleveland

PTY

Panama City

$651

Roundtrip

found 2 days ago

Sat, Aug 8 - Sat, Aug 29

LAX

Los Angeles

PTY

Panama City

$662

Roundtrip

found 4 days ago

Fri, Oct 16 - Mon, Oct 19

LAX

Los Angeles

PTY

Panama City

$667

Roundtrip

found 3 hours ago

Deals For This Weekend's Flights

Origin	Destination	Travel Dates	Flights From*
SJO	Tocumen	April 17 to April 19	$275
MIA	Tocumen	April 17 to April 19	$420
MEX	Tocumen	April 19 to May 11	$447
FLL	Tocumen	April 17 to April 20	$558
JFK	Tocumen	April 17 to April 19	$708
JFK	Tocumen	April 17 to April 19	$708
LAX	Tocumen	April 19 to May 2	$719
ATL	Tocumen	April 19 to April 26	$1,210

*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic Panama Accommodation Deals

Metro Hotel Panama

Via Veneto, Calle D El Cangrejo Panama City Panama

Fully refundableReserve now, pay when you stay

$51 nightly

$57 total

Apr 15 - Apr 16

Total with taxes and fees

Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Albrook Shopping Mall ...

Hotel Centroamericano

Avenida Ecuador y Justo Arosemena Panama City Panama

Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Albrook Shopping Mall ...

Get rates

Hospedium Princess Hotel Panama

Calle 53 Marbella y Avenida 5a B sur Panama City Panama

Fully refundable

$50 nightly

$55 total

May 13 - May 14

Total with taxes and fees

Stay at this hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the overall value in our ...

7.4/10 Good! (818 reviews)

Habian cucarachas en los baños pero el desayuno estaba delicioso. el wifi también estaba muy malo, pero la ubicación muy buena

Reviewed on Apr 13, 2026

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Hotel Coral Suites

Calle D El Cangrejo Panama City Panama

Fully refundableReserve now, pay when you stay

$69 nightly

$76 total

May 1 - May 2

Total with taxes and fees

Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the ...

8.8/10 Excellent! (1,009 reviews)

The kitchen was okay it could have used a couple more things like maybe roasting pan to reheat food but it had the basic minimums which was sufficient. The stop was very polite helpful as well, parking was very easy very secure.

Reviewed on Apr 12, 2026

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top Panama Apartment Hotels

Hotel Coral Suites

Calle D El Cangrejo Panama City Panama

Fully refundableReserve now, pay when you stay

$69 nightly

$76 total

May 1 - May 2

Total with taxes and fees

Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the ...

8.8/10 Excellent! (1,009 reviews)

Reviewed on Apr 12, 2026

Tropical Suites Hotel

First Street, Bocas Town Bocas del Toro

$151 nightly

$166 total

May 5 - May 6

Total with taxes and fees

Book a stay at this business-friendly hotel in Bocas del Toro. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Bolivar Park and ...

9.2/10 Wonderful! (310 reviews)

Nice pool area, great location, great food

Reviewed on Apr 12, 2026

Torres de Alba Hotel & Suites

Calle Eusebio A. Morales y Calle 55 Panama City Panama

Fully refundableReserve now, pay when you stay

$92 nightly

$102 total

Apr 14 - Apr 15

Total with taxes and fees

Book a stay at this business-friendly aparthotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...

8.8/10 Excellent! (538 reviews)

Simply The Best!!!

Reviewed on Apr 4, 2026

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Aparthotel Sevilla Suites

Ave. Eusebio A Morales Panama City

Book a stay at this business-friendly aparthotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition ...

8.8/10 Excellent! (44 reviews)

My stay was cut short due to requirements to leave 1 week earlier because of closure to the airport. Management very understanding, and made refund immediately due to the unforeseen circumstances.......Overall my stay was pleasant.

Reviewed on Mar 31, 2020

Get rates

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic Panama Accommodation Deals

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

Fully refundableReserve now, pay when you stay

$138 nightly

$151 total

May 5 - May 6

Total with taxes and fees

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...

9/10 Wonderful! (5,292 reviews)

Everything excellent

Reviewed on Apr 13, 2026

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama

Fully refundable

$133 nightly

$146 total

May 4 - May 5

Total with taxes and fees

Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...

8.6/10 Excellent! (2,511 reviews)

Nice airport hotel. Nothing amazing. Nice pool. Restaurant onsite was decent for dinner. Breakfast buffet was good. Worth the extra price. Shuttle to airport only goes once an hour which is a little annoying. Had to take a cab there since we missed it by 5 minutes.

Reviewed on Apr 13, 2026

Sheraton Grand Panama

Via Israel And 77th Street Panama City Panama

Fully refundableReserve now, pay when you stay

$127 nightly

$139 total

May 1 - May 2

Total with taxes and fees

Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...

8.6/10 Excellent! (1,005 reviews)

The hotel needs urgently a renovation. The staff is poorly trained

Reviewed on Apr 12, 2026

Save an average of 15% on thousands of hotels when you're signed in

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama

Fully refundableReserve now, pay when you stay

$114 nightly

$125 total

Apr 20 - Apr 21

Total with taxes and fees

Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...

7.8/10 Good! (1,013 reviews)

Excellent

Reviewed on Apr 11, 2026

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Panama

The Westin Playa Bonita Panama

Km 6 Road to Veracruz Veracruz Panama

Fully refundableReserve now, pay when you stay

$202 nightly

$222 total

May 1 - May 2

Total with taxes and fees

Book a stay at this luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...

8/10 Very Good! (1,018 reviews)

Families like: Outdoor pools, kids club, playground, babysitting

Travelers say...

Great place to stay. Wish there was a better beach. Be careful when Expedia advertises the price as all inclusive because it’s NOT…you’ll be in for a surprise once you get there and check in!!

Reviewed on Apr 11, 2026

TRYP by Wyndham Panamá Centro

Via Veneto, El Cangrejo Bellavista Panama City Panama

Fully refundableReserve now, pay when you stay

$98 nightly

$108 total

May 3 - May 4

Total with taxes and fees

Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the ...

9.2/10 Wonderful! (1,010 reviews)

Noisy AC

Reviewed on Apr 12, 2026

Gran Evenia Bijao - All Inclusive

Carretera Interamericana km 108, guias de Anton Rio Hato Coclé

Book a stay at this luxury hotel in Rio Hato. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Playa Blanca and Santa Clara Beach are located ...

7.4/10 Good! (1,000 reviews)

Families like: Outdoor pools, free waterpark access, kids club, playground

Travelers say...

Receptionist was very serious, employees should look happy as they are enjoying their job.

Reviewed on Mar 8, 2026

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Hotel Riu Playa Blanca - All Inclusive

Finca 43.668 Rio Hato Cocle

Book a stay at this beach property in Rio Hato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...

8/10 Very Good! (1,007 reviews)

Families like: Outdoor pools, waterslide, playground, on the beach

Travelers say...

It was my third time at this Riu and I always recommend it to everyone. I traveled with my 3 small kids and they loved the Infinity pool. I used RiuLand as much as I could. The kids loved spending time in the childcare. Lucas and Alvin were great bartenders at Limon Bar. I also recommend getting ...

Reviewed on Apr 10, 2026

Get rates

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark or similar

4 people

Compact

Ford Focus or similar

4 people

Midsize

Toyota Corolla or similar

5 people

SUV

Jeep Compass or similar

5 people

Panama

If you are looking for affordable flights to Panama, look no further. Orbitz offers discounted rates to many destinations.

Bargain flights to Panama now available

As you review your budget and travel plans, consider the low fares Orbitz offers on Panama flights. With Orbitz, booking flights to Panama is easy and the lowest prices are guaranteed.

Easy self-help service offered

Orbitz offers cutting edge mobile tools that allow you to review and make bookings from your Android or iPhone mobile device with a simple application. You can easily and conveniently update your information or book your trip using this service. You are also able to obtain information on affordable hotel packages and receive frequent flight updates. You will receive confirmation of bookings or reservations made using the mobile service on the same day of the request. Change details or receive updates on your Panama flights by visiting the Orbitz site or mobile application.

Orbitz looks after you

Orbitz ensures that you are kept informed with up-to-date flight information, providing feedback to up to six contact numbers to ensure that everyone receives the feedback. In addition to providing the discounted deals on Panama flights, Orbitz is also able to structure a package based on your needs for activities, car hire and accommodations.

Traveler profile updates

After booking your Panama flights, you may access your account profile on the Orbitz site and update your frequent flyer or loyalty membership details. This information will remain on the system and will be available for you to access when you make any future bookings with Orbitz.

Frequently asked questions

Which airlines fly to Panama?

With 24 airlines waiting to whisk you away to Panama, finding an ideal flight will be a breeze. Book a ticket with one of these top international carriers that operate services to Tocumen Intl. Airport (PTY):

Copa Airlines - 2,281 flights to Panama per month
United Airlines - 52 flights to Panama per month
American Airlines - 33 flights to Panama per month

How much is a flight to Panama?

Lots of fantastic deals were up for the taking this week, with return flights to Panama ranging between $258 and $1,210. But it was jet-setters starting their trip from San José (SJO) who scored the best bargains. One-way flights to Panama fell to just $125.

How to book the cheapest flight to Panama?

With Orbitz, you'll find some of the most amazing flight deals around from a big selection of airlines. But if you'd like to heighten your chances of nabbing cheap flights to Panama, here are a few pointers we think will help:

Consider taking off from or landing at alternative airports for a better deal. Enter your preferred departure and arrival points in the form fields, then click on the 'Nearby airports' function below. It will list the available options.
If you're flexible with your itinerary, click on the 'Show flexible dates' link. It'll show the flight deals for the days around your chosen departure. Airfares often vary depending on what day of the week it is.
To filter your results, hit 'Show options.' You can search based on seating class, airlines, and nonstop and refundable flights. You can also select your preferred departure and arrival times under 'Sort & Filter' to the left.
The early bird gets the most impressive deals, so book as soon as you've worked out your travel dates. The cheapest fares go like hotcakes and prices generally climb as the departure date nears.
Consider bundling your flights, hotels and car rental into an Orbitz package deal — the more you book, the more you save.
Flying during the busy season means pricey airfares. Try to travel outside of popular dates, such as Thanksgiving, New Year's Eve and Easter.

What is the best time to book a flight to Panama?

Generally speaking, January is the ideal time to book your plane ticket. This is followed by February and August. Keep this in mind while searching for a cheap flight to Panama.

What day of the week is the cheapest to book a flight to Panama?

Land a fantastic flight deal by booking on a Tuesday, Wednesday or Saturday. These are typically the best days to pick up cheap airfares to Panama.

What is the cheapest day of the week to fly to Panama?

You can pick up cheap flights to Panama by flying out on a Monday, according to Orbitz data from 2020. Tuesday is the next cheapest day, while Saturday has the most costly airfares. Whether you prefer to stretch your travel budget or take off on any day that's convenient, you'll always find a fantastic deal with Orbitz.

What is the cheapest month to fly to Panama?

Consider traveling during August if you don't want to eat into your budget. Orbitz data has found that it's generally the best month for cheap flights to Panama. June is when ticket prices are at their highest.

Which airlines allow free cancellation?

When searching for your Panama flights on Orbitz, choose "Filter by flexible change policies." This filter will show you all the carriers offering free cancellation within 24 hours of booking and no change fees. That means you can breathe easy knowing that if things change, your ticket can too.

What do I need for the flight to Panama?

There's so much to sort out for any big trip, so it's useful to get a bit of help along the way. Here are a few suggestions to ensure you're ready for your flight:

Firstly, you'll need to take all applicable travel documents and identification. How much depends on your place of departure. When booking, you're encouraged to use the correct name, gender and birth date listed on your current ID.
Fill your carry-on bag with snacks and activities and watch time whiz by on this medium-haul flight. If you can, get on the airport's Wi-Fi and save your favorite playlist or podcast to your phone or tablet before take off.
Never mind what the season is at your destination, plane cabins are known to get chilly. Bring an extra layer on your journey to stay warm and comfy.

How do I get cheap first-class/business deals to Panama?

Savvy travelers have a talent for finding business or first-class fares to Panama without the eye-watering price tag. Take their lead with these helpful tips:

Be more flexible with your travel dates and hold out for sales or exclusive offers on business or first-class airfares.
Low-cost airlines offer business-class seats at affordable prices. Ditch the full-service carriers and go with one of these cheaper options.
Take advantage of your airline's flight rewards program and use points to upgrade your seat. Alternatively, you can try bidding for an upgrade in online auctions.

What is the best time to go to Panama?

Travelers come from all over to visit Panama in February, March and May. So if you want to experience this fabulous destination in the busy season, this is the best time to go. Like many places in the Northern Hemisphere, the summer begins June 20 in Panama, with average daily temperatures ranging between 80 ºF and 85 ºF.

Travel tips for Panama

The possibilities for adventure in Panama are almost endless — and Xcaret Eco Theme Park is just one place you'll find it. Grab a car rental, find out how to get to this fabulous attraction and then get cruisin'!
One of Panama's most prominent cities, Panama City is the ideal place to start an epic road trip around this region. Eat, sleep, explore and repeat — it's what getaways are for!

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

$125 Cheap flights to Panama

Top places to visit in Panama

Panama City

Cheap flights to Panama from $125 One Way, $258 Round Trip

Deals For This Weekend's Flights

Find The Perfect Hotel For After Your Flight

Score Epic Panama Accommodation Deals

Metro Hotel Panama

Hotel Centroamericano

Hospedium Princess Hotel Panama

Hotel Coral Suites

Our Top Panama Apartment Hotels

Hotel Coral Suites

Tropical Suites Hotel

Torres de Alba Hotel & Suites

Aparthotel Sevilla Suites

Score Epic Panama Accommodation Deals

Hotel Riu Plaza Panama

Crowne Plaza Panama Airport by IHG

Sheraton Grand Panama

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Family Friendly Hotels in Panama

The Westin Playa Bonita Panama

TRYP by Wyndham Panamá Centro

Gran Evenia Bijao - All Inclusive

Hotel Riu Playa Blanca - All Inclusive

Need a Car For After Your Flight?

Economy

Compact

Midsize

SUV

Panama

Bargain flights to Panama now available

Easy self-help service offered

Orbitz looks after you

Traveler profile updates

Frequently asked questions

Rewards are waiting for you in the Orbitz app