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Residence Inn Durham McPherson/Duke University Medical Cntr

3.0 star property

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Photo gallery for Residence Inn Durham McPherson/Duke University Medical Cntr

Courtyard
In-room safe, desk, laptop workspace, blackout drapes
Lobby lounge
Fitness facility
Exterior

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning
  • Parking available

Explore the area

View in a map
1108 West Main Street, Durham, NC, 27701
  • Place, Brightleaf Square
    ‪3 min walk‬
  • Place, Duke University
    ‪8 min walk‬
  • Place, Durham Performing Arts Center
    ‪16 min walk‬
  • Airport, Raleigh, NC (RDU-Raleigh - Durham Intl.)
    ‪20 min drive‬

Room options

View all photos for Suite, 1 Bedroom

32-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom

8.8 out of 10
Excellent
(6 reviews)
  • 469 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed

9.0 out of 10
Wonderful
(37 reviews)
  • 480 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 Queen Bed with Sofa bed

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 Queen Bed with Sofa bed

9.8 out of 10
Exceptional
(16 reviews)
  • 424 sq ft
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 Bedroom (Hearing Accessible)

8.8 out of 10
Excellent
(3 reviews)
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

10.0 out of 10
Exceptional
(1 review)
  • 478 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

  • 479 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

  • 479 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

  • 426 sq ft
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, Multiple Beds (Mobility Accessible, Tub)

Suite, Multiple Beds (Mobility Accessible, Tub) | In-room safe, desk, laptop workspace, blackout drapes

Suite, Multiple Beds (Mobility Accessible, Tub)

8.0 out of 10
Very good
(2 reviews)
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom (Mobility Accessible, Roll-in Shower)

In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 Bedroom (Mobility Accessible, Roll-in Shower)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free WiFi

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About the neighborhood

Durham

Located in Trinity Park within a short walk of Duke University, Residence Inn Durham McPherson/Duke University Medical Cntr is within a mile (2 km) of other popular sights such as Durham Performing Arts Center. This 147-room, 3-star hotel welcomes guests with free breakfast, a 24-hour gym, and free in-room WiFi.

What's nearby

  • Brightleaf Square - 3 min walk - 0.2 miles
  • Duke University - 8 min walk - 0.4 miles
  • Durham Convention Center - 12 min walk - 0.7 miles
  • Durham Performing Arts Center - 16 min walk - 0.9 miles
  • Durham Bulls Athletic Park - 18 min walk - 1.0 mile

Getting around

  • Durham Station - 8 min walk
  • Raleigh-Durham International Airport (RDU) - 21 min drive

Restaurants

  • ‪Atomic Clock Brewing Co - ‬11 min walk
  • ‪The Federal - ‬3 min walk
  • ‪Grub Durham - ‬12 min walk
  • ‪The Can Opener - ‬7 min walk
  • ‪It's A Southern Thing - ‬7 min walk

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

Renovated in 2024, Residence Inn Durham McPherson/Duke University Medical Cntr offers a 24-hour gym, free WiFi in public areas, and conference space. If you drive, self parking is USD 15 per day, and there's also a free area shuttle. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a business center, coffee/tea in a common area, and a computer station.
Guests can expect to find free WiFi and 32-inch Smart TVs with cable channels and Netflix. Bathrooms have hair dryers and free toiletries. Other standard amenities include kitchens, sitting areas, and refrigerators. Housekeeping is available on request.
Recreational amenities at the hotel include a 24-hour fitness center.

Children under 18 years old are not allowed in the swimming pool or fitness facility without adult supervision. Guests under 18 years old are not allowed in the fitness facility.

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free area shuttle
  • Self parking on site (USD 15 per day)
  • Wheelchair-accessible parking available

Food and drink

  • Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
  • Coffee and tea in common areas

Things to do

  • 24-hour gym

Family friendly

  • Dining table
  • Free area shuttle
  • Grocery/convenience store
  • In-room full-sized refrigerator/freezer
  • In-room kitchen
  • In-room microwave
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Wedding services

Business services

  • 2,530 square feet of conference space
  • Business center
  • Computer station

Outdoors

  • Terrace

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 7 accessible parking spaces
  • Assistive listening devices in meeting rooms
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Hardwood flooring in room
  • Lever door handles
  • Thin carpet in room
  • Visual alarms in hallways
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible registration desk (34 inches high)
  • Wheelchair-accessible restaurant

More

  • 5 floors
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Built in 2015
  • Comprehensive recycling policy
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • No plastic drinking straws
  • Renovated entire property - April 2024
  • Smoking not allowed
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 32-inch smart TV with premium cable channels
  • Netflix
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dining table
  • Dishwasher
  • Full-sized refrigerator/freezer
  • Kitchen
  • Microwave
  • Stovetop

More

  • Air conditioning (climate-controlled)
  • Desk
  • Desk chair
  • Energy-saving switches in guestrooms
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Phone
  • Recycling
  • Safe
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Express check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 100.00 per pet (varies based on length of stay)
  • 2 total (100 lbs is the maximum weight per pet)
  • Restrictions apply
  • For more information, guests can reach out to the property at the number on the booking confirmation
  • Service animals exempt from fees

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Self parking fee: USD 15 per day
  • Pet fee: USD 100.00 per pet (varies based on length of stay)
  • Service animals are exempt from fees

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector, a fire extinguisher, and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)
  • Check-in: 3 PM—-midnight
  • Check-out: noon
  • Minimum check-in age: 21
The front desk is open 24 hours a day, and checking in and out are easy with express services. Driving? This property offers parking (fees apply).

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • Onsite safety features include a carbon monoxide detector, a fire extinguisher, and a smoke detector.
  • This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott).

Additional information about polices, regulations, and more:

  • No cribs or infant beds are available.
  • No rollaway or extra beds are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn Durham McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr

Frequently asked questions

Are free cancellation options available at Residence Inn Durham McPherson/Duke University Medical Cntr?

Residence Inn Durham McPherson/Duke University Medical Cntr offers free cancellation on select room rates. For specific requirements, take a look at the cancellation policy on our site.

How much does it cost to stay at Residence Inn Durham McPherson/Duke University Medical Cntr?

As of Jun 16, 2026, prices found for a 1-night stay for 2 adults at Residence Inn Durham McPherson/Duke University Medical Cntr on Jun 28, 2026 start from $179, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What can I see around Residence Inn Durham McPherson/Duke University Medical Cntr?

This hotel is situated in Trinity Park, just steps from Brightleaf Square. You'll also find Durham Performing Arts Center and American Tobacco Campus less than a mile away.

Is parking available on site at Residence Inn Durham McPherson/Duke University Medical Cntr?

Yes, parking is offered for USD 15 per day. Wheelchair-accessible parking is also available for guests.

Does Residence Inn Durham McPherson/Duke University Medical Cntr include a casino on the premises?

No, Residence Inn Durham McPherson/Duke University Medical Cntr doesn't have a casino.

Will I find an indoor pool at Residence Inn Durham McPherson/Duke University Medical Cntr?

No, there is no indoor pool at this hotel.

Is Residence Inn Durham McPherson/Duke University Medical Cntr a good place to stay for couples?

Couples staying at this hotel will appreciate amenities like Netflix and a kitchen as well as wedding services.

Does Residence Inn Durham McPherson/Duke University Medical Cntr have a hot tub?

No, there isn't a spa tub at this hotel.

Does Residence Inn Durham McPherson/Duke University Medical Cntr feature a restaurant that includes a breakfast menu?

Residence Inn Durham McPherson/Duke University Medical Cntr offers free on-the-go breakfast each morning though there is no restaurant.

Will Residence Inn Durham McPherson/Duke University Medical Cntr allow pets to stay free of charge?

Although they can't stay for free, pets are welcome at Residence Inn Durham McPherson/Duke University Medical Cntr for a fee of USD 100.00 per pet, per stay.

Does Residence Inn Durham McPherson/Duke University Medical Cntr have connecting rooms available?

No, there aren't connecting guestrooms at this hotel.

How far is the airport from Residence Inn Durham McPherson/Duke University Medical Cntr?

The closest major airport to Residence Inn Durham McPherson/Duke University Medical Cntr is Raleigh-Durham International Airport (RDU), which is 15 mi away (21 minutes by car).

Are there rooms with balconies that I can book at Residence Inn Durham McPherson/Duke University Medical Cntr?

No, there aren't any guestrooms with balconies at Residence Inn Durham McPherson/Duke University Medical Cntr.

Does Residence Inn Durham McPherson/Duke University Medical Cntr host weddings?

Take advantage of the wedding venue at Residence Inn Durham McPherson/Duke University Medical Cntr if you plan to say "I do" during your trip.

Residence Inn Durham McPherson/Duke University Medical Cntr Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 327 out of 480 reviews
Rating 8 - Good. 107 out of 480 reviews
Rating 6 - Okay. 29 out of 480 reviews
Rating 4 - Poor. 7 out of 480 reviews
Rating 2 - Terrible. 10 out of 480 reviews

9.4/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.4/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Anna F

Liked: Cleanliness, amenities, property conditions & facilities
Courteous staff, spotless rooms, comfortable bed and pillows.
Stayed 4 nights in Dec 2025
Verified

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was great - very friendly staff.
Stayed 2 nights in Sep 2025
Verified

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities
We love this hotel. The staff is excellent and the rooms are well designed and comfortable. The breakfast is delicious.
Stayed 10 nights in Dec 2025
Verified

10/10 Excellent

Syreeta

Liked: Cleanliness, staff & service, amenities
Rooms were spacious and spotless. Customer Service was phenomenal! Housekeeping were friendly and had no problems giving the extra items needed, including extra pillows.
Stayed 2 nights in Feb 2026
Verified

6/10 Okay

Susan

Liked: Cleanliness, amenities, property conditions & facilities
Wi-Fi did not work and we were not told the procedure for paying for parking. Received a $20 ticket.
Stayed 1 night in Mar 2026
Verified

8/10 Good

Minor

Liked: Cleanliness, staff & service
An excellent place to stay!
Stayed 1 night in Feb 2025
Verified

10/10 Excellent

Tim

Liked: Cleanliness, staff & service, amenities
Great stay. The hotel breakfast left a little something to be desired but the room was clean, the staff was helpful. This was everything I expected.
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

Derek

Liked: Cleanliness, staff & service, property conditions & facilities
Was very nice. The staff was very polite when we arrived.
Stayed 1 night in Aug 2025
Verified

8/10 Good

James

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice hotel for the price. Good location. Big rooms. Quiet. Easy parking. Could be a little cleaner.
Stayed 2 nights in Oct 2025
Verified

10/10 Excellent

Judy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location with some incredible Restaurants nearby
Stayed 3 nights in Oct 2024
Verified

10/10 Excellent

Margaret

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great and reasonably priced place to stay as a family in the center of Durham.
Stayed 1 night in Sep 2024
Verified

10/10 Excellent

Wendy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, friendly, great location.
Stayed 1 night in Sep 2024
Verified

10/10 Excellent

Jackson

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice clean room,good breakfast and great staff.
Stayed 4 nights in Nov 2022
Verified

10/10 Excellent

Christopher

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place!
Stayed 3 nights in Dec 2023
Verified

10/10 Excellent

Jo Anne

Liked: Cleanliness, staff & service, property conditions & facilities
Great place
Stayed 2 nights in May 2024
Verified

8/10 Good

Heman

Liked: Cleanliness, amenities, property conditions & facilities
Laura and Tiffany were extremely helpful and accommodating. The whole staff was very friendly and welcoming!
Stayed 9 nights in Jul 2025
Verified

10/10 Excellent

LaMeesha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I am thankful for the very hospitable staff that I encountered at the hotel. Everyone was smiling at the front desk every time I passed by.
Stayed 8 nights in Jun 2025
Verified

10/10 Excellent

Hong

Liked: Cleanliness, staff & service, property conditions & facilities
Nice staff, very helpful. Close to Duke University, great place to stay.
Stayed 6 nights in Jan 2025
Verified

10/10 Excellent

Timmy

Liked: Cleanliness, amenities, property conditions & facilities
It was very clean and the staff was excellent. The stay was really good. The attendant was great at checking.
Stayed 1 night in Jun 2025
Verified

8/10 Good

nicole

Liked: Cleanliness, staff & service, property conditions & facilities
Clean room. Lighting in bathroom needs to be better.
Stayed 1 night in Oct 2025
Verified

4/10 Poor

Alison

Liked: Cleanliness, property conditions & facilities
Room was too hot. Staff did not convert couch to bed as promised; had to remind them
Stayed 1 night in Dec 2025
Verified

2/10 Terrible

David

Disliked: Cleanliness, amenities, property conditions & facilities
Staff is dismissive and rude
Stayed 1 night in Nov 2025
Verified

8/10 Good

Maria

Liked: Cleanliness, staff & service, amenities
Great location! You can walk to great restaurants and coffee shops. The room is clean and spacious. The bed is very comfortable and it felt like a nice treat at the end of long day. The staff is very friendly, specially Tiffani and Laura at the reception desk. They were very helpful and welcoming, always greeting you with a big smile and making sure we were doing fine. I will definitely stay there on my next visit.
Stayed 7 nights in Aug 2025
Verified

10/10 Excellent

Mustafa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
comfortable stay
Stayed 3 nights in Nov 2023
Verified

10/10 Excellent

Reed

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The place to stay if you have business at Duke. Housekeeping is hit-or-miss, but that's par for the course for an extended-stay hotel.
Stayed 6 nights in Apr 2025

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