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Residence Inn Durham McPherson/Duke University Medical Cntr

3.0 star property
Hotel with free breakfast, a short walk to Duke University

Choose dates to view prices

Photo gallery for Residence Inn Durham McPherson/Duke University Medical Cntr

Courtyard
Full-size fridge, microwave, stovetop, dishwasher
Exterior
Lobby lounge
Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub) | 1 bedroom, in-room safe, desk, laptop workspace

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Parking available
  • Bar
  • Kitchen
  • Housekeeping

Explore the area

View in a map
1108 West Main Street, Durham, NC, 27701
  • Place, Duke University
    ‪3 min walk‬
  • Place, Durham Performing Arts Center
    ‪17 min walk‬
  • Place, Duke University Hospital
    ‪2 min drive‬
  • Airport, Raleigh, NC (RDU-Raleigh - Durham Intl.)
    ‪20 min drive‬

Room options

View all photos for Suite, 1 Bedroom

32-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom

9.2 out of 10
Wonderful
(5 reviews)
  • 469 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Studio, 1 King Bed with Sofa bed, Non Smoking

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed, Non Smoking

8.8 out of 10
Excellent
(31 reviews)
  • 480 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 Queen Bed with Sofa bed, Non Smoking

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 Queen Bed with Sofa bed, Non Smoking

9.6 out of 10
Exceptional
(14 reviews)
  • 424 sq ft
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

8.8 out of 10
Excellent
(3 reviews)
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

  • 478 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

  • 479 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

  • 479 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

  • 426 sq ft
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

View all photos for Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub) | 1 bedroom, in-room safe, desk, laptop workspace

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

10.0 out of 10
Exceptional
(1 review)
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

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About the neighborhood

Durham

Located in Downtown Durham within a 5-minute walk of Brightleaf Square, Residence Inn Durham McPherson/Duke University Medical Cntr is within a 15-minute stroll of Duke University. This 147-room, 3-star hotel welcomes guests with free breakfast, a 24-hour gym, and free in-room WiFi.

What's nearby

  • Duke University - 3 min walk - 0.2 miles
  • Durham Bulls Athletic Park - 16 min walk - 0.9 miles
  • Durham Performing Arts Center - 17 min walk - 0.9 miles
  • Duke University Hospital - 2 min drive - 1.7 miles
  • Cameron Indoor Stadium - 6 min drive - 2.5 miles

Getting around

  • Durham Station - 8 min walk
  • Raleigh-Durham International Airport (RDU) - 19 min drive

Restaurants

  • ‪The Can Opener - ‬7 min walk
  • ‪Ramblers - ‬7 min walk
  • ‪Fonda Lupita - ‬3 min walk
  • ‪Emmy Squared - ‬5 min walk
  • ‪Clouds Brewcade + Kitchen - ‬4 min walk

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

Hotel with free breakfast, a short walk to Duke University
Renovated in 2024, Residence Inn Durham McPherson/Duke University Medical Cntr offers a 24-hour gym, free WiFi in public areas, and conference space. If you drive, self parking is USD 15 per day, and there's also a free area shuttle. Front-desk staff can answer questions 24/7, and assist with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include a business center, coffee/tea in a common area, and a computer station.
Guests can expect to find free WiFi and 32-inch Smart TVs with cable channels and Netflix. Bathrooms have hair dryers and free toiletries. Other standard amenities include kitchens, sitting areas, and refrigerators. Housekeeping is available on request.
Recreational amenities at the hotel include a 24-hour fitness center.

Children under 18 years old are not allowed in the swimming pool or fitness facility without adult supervision. Guests under 18 years old are not allowed in the fitness facility.

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free area shuttle
  • Self parking on site (USD 15 per day)
  • Wheelchair-accessible parking available

Food and drink

  • Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
  • A bar/lounge
  • Coffee and tea in common areas

Things to do

  • 24-hour gym

Family friendly

  • Dining table
  • Free area shuttle
  • Grocery/convenience store
  • In-room full-sized refrigerator/freezer
  • In-room kitchen
  • In-room microwave
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Wedding services

Business services

  • 2,530 square feet of conference space
  • Business center
  • Computer station

Outdoors

  • Terrace

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 7 accessible parking spaces
  • Assistive listening devices in meeting rooms
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Hardwood flooring in room
  • Lever door handles
  • Thin carpet in room
  • Visual alarms in hallways
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible registration desk (34 inches high)
  • Wheelchair-accessible restaurant

More

  • 5 floors
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Built in 2015
  • Comprehensive recycling policy
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • No plastic drinking straws
  • Renovated entire property - April 2024
  • Smoking not allowed
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 32-inch smart TV with premium cable channels
  • Netflix
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dining table
  • Dishwasher
  • Full-sized refrigerator/freezer
  • Kitchen
  • Microwave
  • Stovetop

More

  • Air conditioning (climate-controlled)
  • Desk
  • Desk chair
  • Energy-saving switches in guestrooms
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Phone
  • Recycling
  • Safe
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Express check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 100.00 per pet (varies based on length of stay)
  • 2 total (100 lbs is the maximum weight per pet)
  • Restrictions apply
  • For more information, guests can reach out to the property at the number on the booking confirmation
  • Service animals exempt from fees

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Self parking fee: USD 15 per day
  • Pet fee: USD 100.00 per pet (varies based on length of stay)
  • Service animals are exempt from fees

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)
  • Check-in: 3 PM—-midnight
  • Check-out: noon
  • Minimum check-in age: 21
The front desk is open 24 hours a day, and checking in and out are easy with express services. Driving? This property offers parking (fees apply).

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • Onsite safety features include a carbon monoxide detector and a smoke detector.
  • This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott).

Additional information about polices, regulations, and more:

  • No cribs or infant beds are available.
  • No rollaway or extra beds are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn Durham McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr

Frequently asked questions

Are free cancellation options available at Residence Inn Durham McPherson/Duke University Medical Cntr?

Residence Inn Durham McPherson/Duke University Medical Cntr offers free cancellation on select room rates. For specific requirements, take a look at the cancellation policy on our site.

How much does it cost to stay at Residence Inn Durham McPherson/Duke University Medical Cntr?

As of Oct 17, 2025, prices found for a 1-night stay for 2 adults at Residence Inn Durham McPherson/Duke University Medical Cntr on Oct 26, 2025 start from $166.32, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What can I see around Residence Inn Durham McPherson/Duke University Medical Cntr?

This hotel is situated in Downtown Durham, just steps from Brightleaf Square. You'll also find Carolina Theatre and Durham Performing Arts Center less than a mile away.

Will I be able to park at Residence Inn Durham McPherson/Duke University Medical Cntr?

Yes, parking is offered for USD 15 per day. Accessible parking is also available for guests.

Does Residence Inn Durham McPherson/Duke University Medical Cntr include a casino on the premises?

No, Residence Inn Durham McPherson/Duke University Medical Cntr doesn't have a casino.

Will I find an indoor pool at Residence Inn Durham McPherson/Duke University Medical Cntr?

No, there is no indoor pool at this hotel.

What amenities will couples enjoy at Residence Inn Durham McPherson/Duke University Medical Cntr?

Couples staying at this hotel will appreciate amenities like a kitchen and Netflix as well as a bar.

Are there hot tubs at Residence Inn Durham McPherson/Duke University Medical Cntr?

No, this hotel doesn't have a spa tub.

Does Residence Inn Durham McPherson/Duke University Medical Cntr feature a restaurant that includes a breakfast menu?

Residence Inn Durham McPherson/Duke University Medical Cntr offers free on-the-go breakfast each morning though there is no restaurant.

Will Residence Inn Durham McPherson/Duke University Medical Cntr allow pets to stay free of charge?

Although they can't stay for free, pets are welcome at Residence Inn Durham McPherson/Duke University Medical Cntr for a fee of USD 100.00 per pet, per stay.

Are there connecting rooms at Residence Inn Durham McPherson/Duke University Medical Cntr?

No, there aren't connecting guestrooms at this hotel.

How far is the airport from Residence Inn Durham McPherson/Duke University Medical Cntr?

The closest major airport to Residence Inn Durham McPherson/Duke University Medical Cntr is Raleigh-Durham International Airport (RDU), which is 15 mi away (19 minutes by car).

Can I book a room with a balcony at Residence Inn Durham McPherson/Duke University Medical Cntr?

No, at Residence Inn Durham McPherson/Duke University Medical Cntr, there aren't any guestrooms that list a balcony.

Does Residence Inn Durham McPherson/Duke University Medical Cntr host weddings?

Take advantage of the wedding venue at Residence Inn Durham McPherson/Duke University Medical Cntr if you plan to say "I do" during your trip.

Reviews

Residence Inn Durham McPherson/Duke University Medical Cntr Reviews

9.2

Wonderful

9.4/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.4/10

Property conditions & facilities

9.0/10

Eco-friendliness
Rating 10 - Excellent. 307 out of 448 reviews
Rating 8 - Good. 102 out of 448 reviews
Rating 6 - Okay. 25 out of 448 reviews
Rating 4 - Poor. 6 out of 448 reviews
Rating 2 - Terrible. 8 out of 448 reviews

Reviews

10/10 Excellent

Kaiqing, Singapore

Liked: Cleanliness, staff & service, property conditions & facilities
All good as expected
Stayed 14 nights in Jul 2025

8/10 Good

Heman, Eagle River

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
Laura and Tiffany were extremely helpful and accommodating. The whole staff was very friendly and welcoming!
Stayed 9 nights in Jul 2025

10/10 Excellent

Talal

Stayed 2 nights in Jun 2025

8/10 Good

Lourdes Dolores

Liked: Cleanliness, property conditions & facilities, room comfort

Wasteful shower design

The room was clean and comfortable and the gym was good. However, I gave the hotel 3 stars because the shower lets out so much water that it is actually wasting water. There's no door for the shower, so when you bathe, the water streams out of the shower and onto the bathroom floor. So much water streams out that I had to place the bathmat 12 inches away from the shower entrance so that it wouldn't get wet.
Stayed 10 nights in Jun 2025

8/10 Good

PRAVEEN

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Good place to stay ...convenient to walk to Duke

The check in was super nice. The air conditioner was making a lot of noise - a racket. We had to complain multiple times. But they did respond 🙄 after the third vociferous complaint and replaced compressor. Friendly maintainence team , Barry the maintainence executive brought in a lot of smiles with his attitude.
Stayed 14 nights in Jun 2025

10/10 Excellent

LaMeesha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I am thankful for the very hospitable staff that I encountered at the hotel. Everyone was smiling at the front desk every time I passed by.
Stayed 8 nights in Jun 2025

10/10 Excellent

Timmy

Liked: Cleanliness, amenities, property conditions & facilities
It was very clean and the staff was excellent. The stay was really good. The attendant was great at checking.
Stayed 1 night in Jun 2025

10/10 Excellent

Daneen

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in May 2025

10/10 Excellent

David

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We love staying here when we come to visit our family. Every stay has been wonderful. The room is very comfortable. We love the gym and the breakfasts. Having a nice laundry area on the premises is also a huge plus. The best part is the fantastic staff-everyone is so nice and helpful. Thank you for always making our trips memorable.
Stayed 7 nights in May 2025

6/10 Okay

Tian

Traveled with family
Disliked: Staff & service, amenities
It smelled musky and like urine in our room and much of the facility just smelled like cleaning supplies. The wifi wasn’t great in the room. The location is decently close to Duke, but the immediate area is at a street intersection right by a gas station. There was plenty of parking for pay by mobile 15$.
Stayed 1 night in May 2025

10/10 Excellent

douglas

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in May 2025

8/10 Good

Robert

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Shoutout to Tiffany/Stephanie? on front desk duty - she greeted us with a warm welcome & useful information!
Stayed 1 night in May 2025

10/10 Excellent

Reed

Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The place to stay if you have business at Duke. Housekeeping is hit-or-miss, but that's par for the course for an extended-stay hotel.
Stayed 6 nights in Apr 2025

10/10 Excellent

Andrea

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Apr 2025

10/10 Excellent

Verified traveler

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great value, good location, decent breakfast

Clean, walking distance to gas stations and restaurants.,, decent breakfast in the morning that was free so can't complain... free hot coffee all day... spacious and well-decorated rooms with good cable and smart tvs. All around, great value for the price
Stayed 2 nights in Jan 2025

10/10 Excellent

chantal

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Hong

Liked: Cleanliness, staff & service, property conditions & facilities
Nice staff, very helpful. Close to Duke University, great place to stay.
Stayed 6 nights in Jan 2025

10/10 Excellent

Kenneth, Virginia Beach

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Jan 2025

8/10 Good

Minor, Greenville

Liked: Cleanliness, staff & service
An excellent place to stay!
Stayed 1 night in Feb 2025

8/10 Good

Irina

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Peter

Stayed 1 night in Jan 2025

10/10 Excellent

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Nov 2024

10/10 Excellent

Cynthia

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Loved Tiffani. Beautiful facility.

The hotel was beautiful, conveniently octane the suite was immaculate. The receptionist,Tiffani, was kind and charming, a great representative of your company.
Stayed 1 night in Dec 2024

10/10 Excellent

Joseph

Stayed 1 night in Nov 2024

10/10 Excellent

Swarup

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Stuffs are nice!
Stayed 1 night in Dec 2024

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