Cheap flights from TYS to TPA (McGhee Tyson to Tampa Intl.)

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Cheap Flights from TYS to TPA starting at $109 One Way, $227 Round Trip

Prices starting at $227 for return flights and $109 for one-way flights to Tampa Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Oct 27 - Thu, Oct 29
TYS
Knoxville
TPA
Tampa
$227 Roundtrip, found 5 days ago
$227
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Oct 27 from Knoxville to Tampa, returning Thu, Oct 29, priced at $227 found 5 days ago
Fri, Dec 11 - Thu, Dec 17
TYS
Knoxville
TPA
Tampa
$261 Roundtrip, found 4 hours ago
$261
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Fri, Dec 11 from Knoxville to Tampa, returning Thu, Dec 17, priced at $261 found 4 hours ago
Fri, Feb 19 - Sat, Feb 27
TYS
Knoxville
TPA
Tampa
$261 Roundtrip, found 7 hours ago
$261
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Fri, Feb 19 from Knoxville to Tampa, returning Sat, Feb 27, priced at $261 found 7 hours ago

Hotel Ideas near Tampa Intl.

Airport Hotels near Tampa Intl.

Tampa Airport Marriott

Tampa Airport Marriott

3.5 out of 5
4200 George J. Bean Parkway Tampa FL
$265 nightly
The price is $301 total per night from Oct 25 to Oct 26
$301 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this family-friendly hotel in Tampa. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
Tampa Airport Marriott
Four Points by Sheraton Suites Tampa Airport Westshore

Four Points by Sheraton Suites Tampa Airport Westshore

3 out of 5
4400 W Cypress St Tampa FL
$93 nightly
The price is $106 total per night from Nov 2 to Nov 3
$106 total
Nov 2 - Nov 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
Four Points by Sheraton Suites Tampa Airport Westshore
The Westin Tampa Bay

The Westin Tampa Bay

4 out of 5
7627 W Courtney Campbell Cswy Tampa FL
$163 nightly
The price is $185 total per night from Oct 25 to Oct 26
$185 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this beach hotel in Tampa. Enjoy free WiFi, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
The Westin Tampa Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Tampa

Four Points by Sheraton Suites Tampa Airport Westshore

Four Points by Sheraton Suites Tampa Airport Westshore

3 out of 5
4400 W Cypress St Tampa FL
$93 nightly
The price is $106 total per night from Nov 2 to Nov 3
$106 total
Nov 2 - Nov 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
Four Points by Sheraton Suites Tampa Airport Westshore
The Westin Tampa Bay

The Westin Tampa Bay

4 out of 5
7627 W Courtney Campbell Cswy Tampa FL
$163 nightly
The price is $185 total per night from Oct 25 to Oct 26
$185 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this beach hotel in Tampa. Enjoy free WiFi, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
The Westin Tampa Bay
OASIS BAY SUITES, Tampa, Busch Gardens, USF

OASIS BAY SUITES, Tampa, Busch Gardens, USF

3 out of 5
3001 University Center Dr Tampa FL
$112 nightly
The price is $127 total per night from Oct 11 to Oct 12
$127 total
Oct 11 - Oct 12
Total with taxes and fees
Stay at this hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Busch Gardens Tampa Bay and Seminole Hard Rock Casino Tampa ...
OASIS BAY SUITES, Tampa, Busch Gardens, USF
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Tampa Hotels With Airport Transportation

Hampton Inn & Suites Tampa Airport Avion Park Westshore

Hampton Inn & Suites Tampa Airport Avion Park Westshore

3 out of 5
5329 Avion Park Drive Tampa FL
$133 nightly
The price is $151 total per night from Oct 30 to Oct 31
$151 total
Oct 30 - Oct 31
Total with taxes and fees
Stay at this hotel in Tampa. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the helpful staff in our reviews. ...
Hampton Inn & Suites Tampa Airport Avion Park Westshore
La Quinta Inn Tampa Airport Stadium Westshore

La Quinta Inn Tampa Airport Stadium Westshore

3 out of 5
4730 W Spruce St Tampa FL
$81 nightly
The price is $92 total per night from Oct 12 to Oct 13
$92 total
Oct 12 - Oct 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
La Quinta Inn Tampa Airport Stadium Westshore
Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East

2.5 out of 5
4750 N Dale Mabry Hwy Tampa FL
$89 nightly
The price is $101 total per night from Oct 25 to Oct 26
$101 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.2/10 Good! (2,043 reviews)
"My son and I booked a room for two nights and were attending the Packers/Buccaneers game on Sunday 10/4. We attended a Packer pregame party on Saturday and not being real big partiers, decided to pick up a few pizzas to eat in our room and watch the Brewers/Padres playoff game. Well, we found out ..."

Reviewed on Oct 6, 2026

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Tampa Hotels

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East

2.5 out of 5
4750 N Dale Mabry Hwy Tampa FL
$89 nightly
The price is $101 total per night from Oct 25 to Oct 26
$101 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.2/10 Good! (2,043 reviews)
"My son and I booked a room for two nights and were attending the Packers/Buccaneers game on Sunday 10/4. We attended a Packer pregame party on Saturday and not being real big partiers, decided to pick up a few pizzas to eat in our room and watch the Brewers/Padres playoff game. Well, we found out ..."

Reviewed on Oct 6, 2026

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East
The Godfrey Hotel & Cabanas Tampa

The Godfrey Hotel & Cabanas Tampa

3.5 out of 5
7700 W. Courtney Campbell Causeway Tampa FL
Book a stay at this business-friendly hotel in Tampa. Enjoy 2 outdoor pools, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Get rates
The Godfrey Hotel & Cabanas Tampa
La Quinta Inn by Wyndham Tampa Near Busch Gardens

La Quinta Inn by Wyndham Tampa Near Busch Gardens

3 out of 5
9202 N 30th St Tampa FL
$76 nightly
The price is $86 total per night from Oct 12 to Oct 13
$86 total
Oct 12 - Oct 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
7.4/10 Good! (3,041 reviews)
"The good thing about the property is it is near Busch Gardens, other than that it is definitely what you get from a 2 star property. Noisy AC, wood floors coming apart in the room, leaky shower, no safe in room, floors were not swept, stained shower curtain."

Reviewed on Oct 6, 2026

La Quinta Inn by Wyndham Tampa Near Busch Gardens
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Tampa

Chase Suite Hotel Rocky Point Tampa

Chase Suite Hotel Rocky Point Tampa

3 out of 5
3075 N Rocky Point Dr Tampa FL
Book a stay at this business-friendly aparthotel in Tampa. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the ...
8/10 Very Good! (1,256 reviews)
"Ok"

Reviewed on Aug 4, 2025

Get rates
Chase Suite Hotel Rocky Point Tampa
Hyatt Place Busch Gardens

Hyatt Place Busch Gardens

3 out of 5
11408 N 30th St Tampa FL
$110 nightly
The price is $125 total per night from Oct 13 to Oct 14
$125 total
Oct 13 - Oct 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.4/10 Very Good! (1,502 reviews)
"The staff were excellent! Exceptionally helpful and polite."

Reviewed on Oct 5, 2026

Hyatt Place Busch Gardens
Sailport Waterfront Suites

Sailport Waterfront Suites

3.5 out of 5
2506 N Rocky Point Dr Tampa FL
$128 nightly
The price is $143 total per night from Oct 13 to Oct 14
$143 total
Oct 13 - Oct 14
Total with taxes and fees
Book a stay at this business-friendly aparthotel in Tampa. Enjoy breakfast (surcharge), a fitness center, and a 24-hour front desk. Our guests praise the pool ...
8.4/10 Very Good! (5,263 reviews)
"The room was dirty. The tub has a big hole in the side. Cabinets dirty...under the sink disgusting. Dish washer filter. Noisey. I had to wear air plugs to bed. Never stay again."

Reviewed on Oct 6, 2026

Sailport Waterfront Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TYS to TPA Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York
TPA Address & GPS
Address:
5507 West Spruce Street
Tampa FL, 33607
United States
IATA Code:
TPA
Longitude:
-82.535415
Latitude:
27.979869
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from McGhee Tyson Airport (TYS) to Tampa Intl. Airport (TPA)?
You're going to have to switch planes if you're wanting to get from TYS to Tampa Intl. Airport (TPA). Numerous companies operate on this route with only one stopover, including American Airlines, Delta Air Lines and United Airlines.
What is the shortest flight from Knoxville Airport to Tampa Intl. Airport (TPA)?
From Knoxville, the exciting sights and sounds of Tampa are around 4 hours and 43 minutes away. Make sure you choose your favorite seat, or perhaps even upgrade to one with a bit more legroom, and get to your destination in total comfort.
How many hours flight from McGhee Tyson Airport (TYS) to Tampa Intl. Airport (TPA)?
On average, it takes 4 hours and 50 minutes to travel from Knoxville Airport to TPA. You'll be in the air for a while, so contemplate bringing your own entertainment, like a newspaper or your travel journal.
What airlines have the most flights from Knoxville Airport to TPA?
Do some people-watching, pick up a doughnut, strike up a conversation with a stranger ... Airport stopovers don't have to be something to dread! If you're heading from Knoxville to Tampa, there are no direct flights. Be prepared for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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