Cheap flights from TYS to TPA (McGhee Tyson to Tampa Intl.)

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Cheap Flights from TYS to TPA starting at $100 One Way, $287 Round Trip

Prices starting at $287 for return flights and $100 for one-way flights to Tampa Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, May 22 - Sat, May 30
TYS
Knoxville
TPA
Tampa
$287 Roundtrip, just found
$287
Roundtrip
just found
Select Frontier Airlines flight, departing Fri, May 22 from Knoxville to Tampa, returning Sat, May 30, priced at $287 just found
Fri, May 22 - Sat, May 30
TYS
Knoxville
TPA
Tampa
$293 Roundtrip, just found
$293
Roundtrip
just found
Select Frontier Airlines flight, departing Fri, May 22 from Knoxville to Tampa, returning Sat, May 30, priced at $293 just found
Fri, May 22 - Sat, May 30
TYS
Knoxville
TPA
Tampa
$293 Roundtrip, just found
$293
Roundtrip
just found
Select Frontier Airlines flight, departing Fri, May 22 from Knoxville to Tampa, returning Sat, May 30, priced at $293 just found
Thu, May 28 - Mon, Jun 1
TYS
Knoxville
TPA
Tampa
$318 Roundtrip, found 3 days ago
$318
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, May 28 from Knoxville to Tampa, returning Mon, Jun 1, priced at $318 found 3 days ago
Thu, May 28 - Mon, Jun 1
TYS
Knoxville
TPA
Tampa
$321 Roundtrip, found 3 days ago
$321
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, May 28 from Knoxville to Tampa, returning Mon, Jun 1, priced at $321 found 3 days ago

Hotel Ideas near Tampa Intl.

Airport Hotels near Tampa Intl.

Grand Hyatt Tampa Bay

Grand Hyatt Tampa Bay

4 out of 5
2900 Bayport Drive Tampa FL
$265 nightly
The price is $301 total per night from May 10 to May 11
$301 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,236 reviews)
Where do I start……I booked a suite & also a separate room for family. I specifically requested the extra room to be 2 queens. When we got to the hotel at 4:30, the extra room had been changed to just a king and wasn’t even ready. That started the experience on the wrong foot. We had to wait for the ...

Reviewed on May 6, 2026

Grand Hyatt Tampa Bay
Tampa Airport Marriott

Tampa Airport Marriott

3.5 out of 5
4200 George J. Bean Parkway Tampa FL
$212 nightly
The price is $240 total per night from Jun 7 to Jun 8
$240 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this family-friendly hotel in Tampa. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
9.2/10 Wonderful! (1,256 reviews)
Never knew they had a pool

Reviewed on May 5, 2026

Tampa Airport Marriott
Hilton Tampa Airport Westshore

Hilton Tampa Airport Westshore

4 out of 5
2225 N Lois Ave Tampa FL
$129 nightly
The price is $146 total per night from May 22 to May 23
$146 total
May 22 - May 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the helpful ...
8.6/10 Excellent! (1,312 reviews)
Upon arrival into TPA, the shuttle bus was requested using a courtesy phone in the airport (as it was late). It arrived quickly and was easy to find. The hotel check in was quick and efficient and the staff were very friendly. The room was clean, large and quiet, even though the hotel was so close ...

Reviewed on May 7, 2026

Hilton Tampa Airport Westshore
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Tampa

OASIS BAY SUITES, Tampa, Busch Gardens, USF

OASIS BAY SUITES, Tampa, Busch Gardens, USF

3 out of 5
3001 University Center Dr Tampa FL
$139 nightly
The price is $158 total per night from May 12 to May 13
$158 total
May 12 - May 13
Total with taxes and fees
Stay at this hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Busch Gardens Tampa Bay and Seminole Hard Rock Casino Tampa ...
8.6/10 Excellent! (2,210 reviews)
This place was the absolute cleanest place we have ever stayed at, even the outside was immaculate. We were so impressed. There was not only a pool outside but an amazing sitting area with lots of activities for kids. We definitely will go back😊

Reviewed on May 7, 2026

OASIS BAY SUITES, Tampa, Busch Gardens, USF
Hotel South Tampa & Suites

Hotel South Tampa & Suites

3 out of 5
3314 S Dale Mabry Hwy Tampa FL
$99 nightly
The price is $112 total per night from May 11 to May 12
$112 total
May 11 - May 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,758 reviews)
Quiet clean room for one nite stay. Will be back in one month for another stay !!! Convenient location with adequate parking !!

Reviewed on May 5, 2026

Hotel South Tampa & Suites
Grand Hyatt Tampa Bay

Grand Hyatt Tampa Bay

4 out of 5
2900 Bayport Drive Tampa FL
$265 nightly
The price is $301 total per night from May 10 to May 11
$301 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,236 reviews)
Where do I start……I booked a suite & also a separate room for family. I specifically requested the extra room to be 2 queens. When we got to the hotel at 4:30, the extra room had been changed to just a king and wasn’t even ready. That started the experience on the wrong foot. We had to wait for the ...

Reviewed on May 6, 2026

Grand Hyatt Tampa Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Tampa Hotels With Airport Transportation

Hampton Inn & Suites Tampa Airport Avion Park Westshore

Hampton Inn & Suites Tampa Airport Avion Park Westshore

3 out of 5
5329 Avion Park Drive Tampa FL
$116 nightly
The price is $132 total per night from Jun 1 to Jun 2
$132 total
Jun 1 - Jun 2
Total with taxes and fees
Stay at this hotel in Tampa. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.2/10 Wonderful! (2,727 reviews)
Great staff, clean room!

Reviewed on May 6, 2026

Hampton Inn & Suites Tampa Airport Avion Park Westshore
La Quinta Inn Tampa Airport Stadium Westshore

La Quinta Inn Tampa Airport Stadium Westshore

3 out of 5
4730 W Spruce St Tampa FL
$85 nightly
The price is $97 total per night from Jun 1 to Jun 2
$97 total
Jun 1 - Jun 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
6.8/10 (1,171 reviews)
We stayed here as an affordable option and close to raymond james stadium for the BTS concert and I was actually quite comfortable. The front desk staff were extremely friendly and accommodating. The room is a bit old but the beds were very comfortable and the size of the room was great! Plenty of ...

Reviewed on May 5, 2026

La Quinta Inn Tampa Airport Stadium Westshore
Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East

2.5 out of 5
4750 N Dale Mabry Hwy Tampa FL
$96 nightly
The price is $109 total per night from Jun 3 to Jun 4
$109 total
Jun 3 - Jun 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7/10 Good! (1,955 reviews)
Justin, Ben and Olivia truly went above and beyond to make us feel welcome! I really can’t say enough about how kind and helpful and patient they were in finding solutions to any problems and making certain that all hotel guests’ needs were anticipated and that guests were made to feel at home! The ...

Reviewed on May 5, 2026

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Tampa Hotels

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East

2.5 out of 5
4750 N Dale Mabry Hwy Tampa FL
$96 nightly
The price is $109 total per night from Jun 3 to Jun 4
$109 total
Jun 3 - Jun 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7/10 Good! (1,955 reviews)
Justin, Ben and Olivia truly went above and beyond to make us feel welcome! I really can’t say enough about how kind and helpful and patient they were in finding solutions to any problems and making certain that all hotel guests’ needs were anticipated and that guests were made to feel at home! The ...

Reviewed on May 5, 2026

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East
The Godfrey Hotel & Cabanas Tampa

The Godfrey Hotel & Cabanas Tampa

3.5 out of 5
7700 W. Courtney Campbell Causeway Tampa FL
Book a stay at this business-friendly hotel in Tampa. Enjoy 2 outdoor pools, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Get rates
The Godfrey Hotel & Cabanas Tampa
Ramada by Wyndham Tampa Westshore Airport South

Ramada by Wyndham Tampa Westshore Airport South

3 out of 5
1200 N Westshore Blvd Tampa FL
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.2/10 (4,340 reviews)
It was very good

Reviewed on May 6, 2026

Get rates
Ramada by Wyndham Tampa Westshore Airport South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Tampa

Chase Suite Hotel Rocky Point Tampa

Chase Suite Hotel Rocky Point Tampa

3 out of 5
3075 N Rocky Point Dr Tampa FL
Book a stay at this business-friendly aparthotel in Tampa. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the ...
8/10 Very Good! (1,589 reviews)
Ok

Reviewed on Aug 4, 2025

Get rates
Chase Suite Hotel Rocky Point Tampa
Hyatt Place Busch Gardens

Hyatt Place Busch Gardens

3 out of 5
11408 N 30th St Tampa FL
$110 nightly
The price is $125 total per night from Jun 7 to Jun 8
$125 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.4/10 Very Good! (1,465 reviews)
Great place!!

Reviewed on May 3, 2026

Hyatt Place Busch Gardens
Sailport Waterfront Suites

Sailport Waterfront Suites

3.5 out of 5
2506 N Rocky Point Dr Tampa FL
$124 nightly
The price is $138 total per night from May 26 to May 27
$138 total
May 26 - May 27
Total with taxes and fees
Book a stay at this business-friendly aparthotel in Tampa. Enjoy breakfast (surcharge), a fitness center, and a 24-hour front desk. Our guests praise the pool ...
8.4/10 Very Good! (5,028 reviews)
The photos show the great views the room has. However the bathroom, kitchen, bedroom, and tvs are dated. This property "thrives" solely due to its location and NOT due to the quality of the rooms. This was my first and LAST time staying at this property. There was not even sufficient soap provided ...

Reviewed on May 7, 2026

Sailport Waterfront Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TYS to TPA Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York
TPA Address & GPS
Address:
5507 West Spruce Street
Tampa FL, 33607
United States
IATA Code:
TPA
Longitude:
-82.535415
Latitude:
27.979869
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from McGhee Tyson Airport (TYS) to Tampa Intl. Airport (TPA)?
You're going to have to switch planes if you're wanting to get from TYS to Tampa Intl. Airport (TPA). Numerous companies operate on this route with only one stopover, including American Airlines, Delta Air Lines and United Airlines.
What is the shortest flight from Knoxville Airport to Tampa Intl. Airport (TPA)?
From Knoxville, the exciting sights and sounds of Tampa are around 4 hours and 43 minutes away. Make sure you choose your favorite seat, or perhaps even upgrade to one with a bit more legroom, and get to your destination in total comfort.
How many hours flight from McGhee Tyson Airport (TYS) to Tampa Intl. Airport (TPA)?
On average, it takes 4 hours and 50 minutes to travel from Knoxville Airport to TPA. You'll be in the air for a while, so contemplate bringing your own entertainment, like a newspaper or your travel journal.
What airlines have the most flights from Knoxville Airport to TPA?
Do some people-watching, pick up a doughnut, strike up a conversation with a stranger ... Airport stopovers don't have to be something to dread! If you're heading from Knoxville to Tampa, there are no direct flights. Be prepared for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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