Cheap flights from TYS to TPA (McGhee Tyson to Tampa Intl.)

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Cheap Flights from TYS to TPA starting at $136 One Way, $182 Round Trip

Prices starting at $182 for return flights and $136 for one-way flights to Tampa Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Apr 30 - Sun, May 3
TYS
Knoxville
TPA
Tampa
$182 Roundtrip, found 2 days ago
$182
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Apr 30 from Knoxville to Tampa, returning Sun, May 3, priced at $182 found 2 days ago
Thu, Apr 16 - Sun, Apr 19
TYS
Knoxville
TPA
Tampa
$246 Roundtrip, found 4 days ago
$246
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Apr 16 from Knoxville to Tampa, returning Sun, Apr 19, priced at $246 found 4 days ago
Thu, Apr 30 - Sun, May 3
TYS
Knoxville
TPA
Tampa
$268 Roundtrip, found 6 days ago
$268
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Apr 30 from Knoxville to Tampa, returning Sun, May 3, priced at $268 found 6 days ago
Thu, Apr 30 - Sun, May 3
TYS
Knoxville
TPA
Tampa
$288 Roundtrip, found 2 days ago
$288
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Apr 30 from Knoxville to Tampa, returning Sun, May 3, priced at $288 found 2 days ago
Wed, Aug 19 - Mon, Aug 24
TYS
Knoxville
TPA
Tampa
$321 Roundtrip, found 3 days ago
$321
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Aug 19 from Knoxville to Tampa, returning Mon, Aug 24, priced at $321 found 3 days ago

Hotel Ideas near Tampa Intl.

Airport Hotels near Tampa Intl.

Grand Hyatt Tampa Bay

Grand Hyatt Tampa Bay

4 out of 5
2900 Bayport Drive Tampa FL
$230 nightly
The price is $261 total per night from Apr 5 to Apr 6
$261 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,215 reviews)
It was everything I hoped for in a luxury stay

Reviewed on Mar 20, 2026

Grand Hyatt Tampa Bay
Ramada by Wyndham Tampa Westshore Airport South

Ramada by Wyndham Tampa Westshore Airport South

3 out of 5
1200 N Westshore Blvd Tampa FL
$93 nightly
The price is $105 total per night from Mar 30 to Mar 31
$105 total
Mar 30 - Mar 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.2/10 (4,187 reviews)
Internet was slow, couldnt handle photo uploads to phone from camera, room was dirty, there was literal dry blood on the elevator light. Very dirty floors/ baseboards. I literally checked the room for bed bugs * did not find any thank goodness. Exremely poor lighting , in rooms and ESPECIALLY on ...

Reviewed on Mar 22, 2026

Ramada by Wyndham Tampa Westshore Airport South
Hilton Garden Inn Tampa Airport Westshore

Hilton Garden Inn Tampa Airport Westshore

3 out of 5
5312 Avion Park Drive Tampa FL
$147 nightly
The price is $167 total per night from Mar 29 to Mar 30
$167 total
Mar 29 - Mar 30
Total with taxes and fees
Stay at this hotel in Tampa. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the restaurant and the helpful staff in our ...
9/10 Wonderful! (2,107 reviews)
Clean room. Comfy beds. Sound proofing walls and windows so you dont hear the airplanes. Definitely will be back.

Reviewed on Mar 21, 2026

Hilton Garden Inn Tampa Airport Westshore
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Tampa

Hotel Tampa Riverwalk

Hotel Tampa Riverwalk

4 out of 5
200 N Ashley Dr Tampa FL
$197 nightly
The price is $224 total per night from Mar 29 to Mar 30
$224 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy 2 bars/lounges, breakfast (surcharge), and a fitness center. Our guests praise the pool and the helpful ...
7/10 Good! (1,803 reviews)
Room and pull out bed that was supposed to be used for my service animal was completely disgusting and stained. Horrible ac and when asked for a fix or to switch rooms, someone came up and had zero affect on the temp. No new room.

Reviewed on Mar 21, 2026

Hotel Tampa Riverwalk
Ramada by Wyndham Tampa Westshore Airport South

Ramada by Wyndham Tampa Westshore Airport South

3 out of 5
1200 N Westshore Blvd Tampa FL
$93 nightly
The price is $105 total per night from Mar 30 to Mar 31
$105 total
Mar 30 - Mar 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.2/10 (4,187 reviews)
Internet was slow, couldnt handle photo uploads to phone from camera, room was dirty, there was literal dry blood on the elevator light. Very dirty floors/ baseboards. I literally checked the room for bed bugs * did not find any thank goodness. Exremely poor lighting , in rooms and ESPECIALLY on ...

Reviewed on Mar 22, 2026

Ramada by Wyndham Tampa Westshore Airport South
Sailport Waterfront Suites

Sailport Waterfront Suites

3.5 out of 5
2506 N Rocky Point Dr Tampa FL
$148 nightly
The price is $166 total per night from Apr 5 to Apr 6
$166 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly aparthotel in Tampa. Enjoy breakfast (surcharge), a fitness center, and a 24-hour front desk. Our guests praise the pool ...
Sailport Waterfront Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Tampa Hotels With Airport Transportation

Hampton Inn & Suites Tampa Airport Avion Park Westshore

Hampton Inn & Suites Tampa Airport Avion Park Westshore

2.5 out of 5
5329 Avion Park Drive Tampa FL
$147 nightly
The price is $167 total per night from Apr 5 to Apr 6
$167 total
Apr 5 - Apr 6
Total with taxes and fees
Stay at this hotel in Tampa. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.2/10 Wonderful! (2,702 reviews)
Room was spotless. Only problem is toilet seats are too close to the floor for men who do not their private parts to get wet.

Reviewed on Mar 21, 2026

Hampton Inn & Suites Tampa Airport Avion Park Westshore
La Quinta Inn Tampa Airport Stadium Westshore

La Quinta Inn Tampa Airport Stadium Westshore

3 out of 5
4730 W Spruce St Tampa FL
$82 nightly
The price is $93 total per night from Apr 20 to Apr 21
$93 total
Apr 20 - Apr 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (1,152 reviews)
Room was actually new and everything was in good shape but the biggest problem was that the shower head didn’t work. The water ran fine from the tap but the head didn’t work. I stayed in room 220

Reviewed on Mar 22, 2026

La Quinta Inn Tampa Airport Stadium Westshore
Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East

2.5 out of 5
4750 N Dale Mabry Hwy Tampa FL
$112 nightly
The price is $127 total per night from Apr 19 to Apr 20
$127 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
6.8/10 (1,895 reviews)
Reasonably nice place in decent shape. Rooms are large with fridge and microwave.

Reviewed on Mar 22, 2026

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Tampa Hotels

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East

2.5 out of 5
4750 N Dale Mabry Hwy Tampa FL
$112 nightly
The price is $127 total per night from Apr 19 to Apr 20
$127 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
6.8/10 (1,895 reviews)
Reasonably nice place in decent shape. Rooms are large with fridge and microwave.

Reviewed on Mar 22, 2026

Country Inn & Suites by Radisson, RJ Stadium - Tampa Airport East
Ramada by Wyndham Tampa Westshore Airport South

Ramada by Wyndham Tampa Westshore Airport South

3 out of 5
1200 N Westshore Blvd Tampa FL
$93 nightly
The price is $105 total per night from Mar 30 to Mar 31
$105 total
Mar 30 - Mar 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.2/10 (4,187 reviews)
Internet was slow, couldnt handle photo uploads to phone from camera, room was dirty, there was literal dry blood on the elevator light. Very dirty floors/ baseboards. I literally checked the room for bed bugs * did not find any thank goodness. Exremely poor lighting , in rooms and ESPECIALLY on ...

Reviewed on Mar 22, 2026

Ramada by Wyndham Tampa Westshore Airport South
La Quinta Inn by Wyndham Tampa Near Busch Gardens

La Quinta Inn by Wyndham Tampa Near Busch Gardens

3 out of 5
9202 N 30th St Tampa FL
$84 nightly
The price is $96 total per night from Mar 30 to Mar 31
$96 total
Mar 30 - Mar 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
7.4/10 Good! (2,864 reviews)
Please was clean and the staff were very nice.

Reviewed on Mar 21, 2026

La Quinta Inn by Wyndham Tampa Near Busch Gardens
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Tampa

Chase Suite Hotel Rocky Point Tampa

Chase Suite Hotel Rocky Point Tampa

3 out of 5
3075 N Rocky Point Dr Tampa FL
Book a stay at this business-friendly aparthotel in Tampa. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the ...
8/10 Very Good! (1,686 reviews)
Ok

Reviewed on Aug 4, 2025

Get rates
Chase Suite Hotel Rocky Point Tampa
Hyatt Place Busch Gardens

Hyatt Place Busch Gardens

3 out of 5
11408 N 30th St Tampa FL
$135 nightly
The price is $153 total per night from Apr 13 to Apr 14
$153 total
Apr 13 - Apr 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.4/10 Very Good! (1,464 reviews)
Amenities was very poor no hot tub dirty pool. This hotel was poor conditions. The pictures are shown up from downtown.

Reviewed on Mar 22, 2026

Hyatt Place Busch Gardens
Sailport Waterfront Suites

Sailport Waterfront Suites

3.5 out of 5
2506 N Rocky Point Dr Tampa FL
$148 nightly
The price is $166 total per night from Apr 5 to Apr 6
$166 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly aparthotel in Tampa. Enjoy breakfast (surcharge), a fitness center, and a 24-hour front desk. Our guests praise the pool ...
Sailport Waterfront Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TYS to TPA Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York
TPA Address & GPS
Address:
5507 West Spruce Street
Tampa FL, 33607
United States
IATA Code:
TPA
Longitude:
-82.535415
Latitude:
27.979869
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from McGhee Tyson Airport (TYS) to Tampa Intl. Airport (TPA)?
You're going to have to switch planes if you're wanting to get from TYS to Tampa Intl. Airport (TPA). Numerous companies operate on this route with only one stopover, including American Airlines, Delta Air Lines and United Airlines.
What is the shortest flight from Knoxville Airport to Tampa Intl. Airport (TPA)?
From Knoxville, the exciting sights and sounds of Tampa are around 4 hours and 43 minutes away. Make sure you choose your favorite seat, or perhaps even upgrade to one with a bit more legroom, and get to your destination in total comfort.
How many hours flight from McGhee Tyson Airport (TYS) to Tampa Intl. Airport (TPA)?
On average, it takes 4 hours and 50 minutes to travel from Knoxville Airport to TPA. You'll be in the air for a while, so contemplate bringing your own entertainment, like a newspaper or your travel journal.
What airlines have the most flights from Knoxville Airport to TPA?
Do some people-watching, pick up a doughnut, strike up a conversation with a stranger ... Airport stopovers don't have to be something to dread! If you're heading from Knoxville to Tampa, there are no direct flights. Be prepared for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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