Cheap flights from TYS to GNV (McGhee Tyson to Gainesville Regional)

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Cheap Flights from TYS to GNV starting at $215 One Way, $233 Round Trip

Prices starting at $233 for return flights and $215 for one-way flights to Gainesville Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Dec 4 - Tue, Dec 16
TYS
Knoxville
GNV
Gainesville
$233 Roundtrip, found 6 hours ago
$233
Roundtrip
found 6 hours ago
Select Delta flight, departing Thu, Dec 4 from Knoxville to Gainesville, returning Tue, Dec 16, priced at $233 found 6 hours ago
Sun, Nov 23 - Thu, Nov 27
TYS
Knoxville
GNV
Gainesville
$242 Roundtrip, found 2 days ago
$242
Roundtrip
found 2 days ago
Select Delta flight, departing Sun, Nov 23 from Knoxville to Gainesville, returning Thu, Nov 27, priced at $242 found 2 days ago
Sun, Nov 23 - Fri, Nov 28
TYS
Knoxville
GNV
Gainesville
$247 Roundtrip, found 2 days ago
$247
Roundtrip
found 2 days ago
Select Delta flight, departing Sun, Nov 23 from Knoxville to Gainesville, returning Fri, Nov 28, priced at $247 found 2 days ago
Thu, Dec 4 - Thu, Dec 11
TYS
Knoxville
GNV
Gainesville
$248 Roundtrip, found 6 hours ago
$248
Roundtrip
found 6 hours ago
Select Delta flight, departing Thu, Dec 4 from Knoxville to Gainesville, returning Thu, Dec 11, priced at $248 found 6 hours ago
Mon, Nov 24 - Thu, Nov 27
TYS
Knoxville
GNV
Gainesville
$263 Roundtrip, found 2 days ago
$263
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Nov 24 from Knoxville to Gainesville, returning Thu, Nov 27, priced at $263 found 2 days ago

Hotel Ideas near Gainesville Regional

Airport Hotels near Gainesville Regional

4 Bedroom Single Family home 5 mins to University!

4 Bedroom Single Family home 5 mins to University!

Gainesville
$241 nightly
The price is $267 total per night from Nov 16 to Nov 17
$267 total
Nov 16 - Nov 17
Total with taxes and fees
Stay at this vacation home in Gainesville. Enjoy free WiFi, laundry facilities, and balconies. Popular attractions Ben Hill Griffin Stadium and Matheson History ...
9/10 Wonderful! (17 reviews)
We had a very nice stay

Reviewed on Oct 11, 2025

4 Bedroom Single Family home 5 mins to University!
Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown

3 out of 5
212 SE 1ST STREET,, Gainesville, FL
$101 nightly
The price is $114 total per night from Dec 3 to Dec 4
$114 total
Dec 3 - Dec 4
Total with taxes and fees
Stay at this 3-star business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,102 reviews)
Great for fest

Reviewed on Oct 29, 2025

Hyatt Place Gainesville Downtown
Sweetwater Branch Inn

Sweetwater Branch Inn

3.5 out of 5
625 East University Avenue, Gainesville, FL
$134 nightly
The price is $151 total per night from Nov 14 to Nov 15
$151 total
Nov 14 - Nov 15
Total with taxes and fees
Stay at this 3.5-star B&B in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (863 reviews)
great room - the man who checked me in was especially friendly, warm and impressive, I arrived late and tired and he made my day!!!!!!

Reviewed on Nov 3, 2025

Sweetwater Branch Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Gainesville

DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville

4 out of 5
3726 Sw 40th Blvd, Gainesville, FL
$89 nightly
The price is $101 total per night from Nov 13 to Nov 14
$101 total
Nov 13 - Nov 14
Total with taxes and fees
Stay at this 4-star hotel in Gainesville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
7.6/10 Good! (1,006 reviews)
Staff was great and so were the housekeeping girls.

Reviewed on Oct 28, 2025

DoubleTree by Hilton Gainesville
Hotel Eleo at the University of Florida

Hotel Eleo at the University of Florida

3 out of 5
1514 Southwest 14th Street, Gainesville, FL
$143 nightly
The price is $161 total per night from Nov 10 to Nov 11
$161 total
Nov 10 - Nov 11
Total with taxes and fees
Stay at this 3-star hotel in Gainesville. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the helpful staff ...
9.4/10 Exceptional! (1,275 reviews)
The room was clean, the staff were courteous and the onsite restaurant had good food and drinks. The valet service was quick and the workers were nice. Would definitely stay there again.

Reviewed on Nov 5, 2025

Hotel Eleo at the University of Florida
HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western

2.5 out of 5
3905 Sw 43Rd St, Gainesville, FL
$81 nightly
The price is $92 total per night from Nov 13 to Nov 14
$92 total
Nov 13 - Nov 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,801 reviews)
Like location Good value

Reviewed on Nov 2, 2025

HOM Hotel Gainesville, SureStay Collection by Best Western
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Gainesville Hotels With Airport Transportation

Best Western Gateway Grand

Best Western Gateway Grand

3 out of 5
4200 NW 97th Blvd, Gainesville, FL
$90 nightly
The price is $101 total per night from Nov 12 to Nov 13
$101 total
Nov 12 - Nov 13
Total with taxes and fees
Stay at this 3-star business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.4/10 Very Good! (1,329 reviews)
Only one towel for a double occupancy room

Reviewed on Nov 2, 2025

Best Western Gateway Grand
Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville

3.5 out of 5
1714 SW 34th St, Gainesville, FL
$98 nightly
The price is $110 total per night from Nov 13 to Nov 14
$110 total
Nov 13 - Nov 14
Total with taxes and fees
Stay at this 3.5-star business-friendly hotel in Gainesville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,009 reviews)
Great location for a college visit for my 2 teens and husband. Nice, clean, customer service was great.

Reviewed on Oct 30, 2025

Hilton University of Florida Conference Center Gainesville
Holiday Inn Gainesville - University Center by IHG

Holiday Inn Gainesville - University Center by IHG

3 out of 5
1250 W University Ave, Gainesville, FL
$99 nightly
The price is $111 total per night from Nov 23 to Nov 24
$111 total
Nov 23 - Nov 24
Total with taxes and fees
Stay at this 3-star golf hotel in Gainesville. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the room service ...
7.6/10 Good! (1,002 reviews)
Clean and very convenient location for dining.

Reviewed on Oct 25, 2025

Holiday Inn Gainesville - University Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Gainesville Hotels

Super 8 by Wyndham Gainesville I-75 Hospital University Area

Super 8 by Wyndham Gainesville I-75 Hospital University Area

2 out of 5
4202 SW 40th Blvd, Gainesville, FL
$50 nightly
The price is $56 total per night from Nov 16 to Nov 17
$56 total
Nov 16 - Nov 17
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,013 reviews)
The carpet in the hallway must of just been cleaned. There where yellow sign stands and a very strong deodorizer smell. The dampness from the carpet was tracked into our room making our floors sticky and dirty. Our socks were filthy after walking on the floors.

Reviewed on Oct 27, 2025

Super 8 by Wyndham Gainesville I-75 Hospital University Area
Travelers Inn

Travelers Inn

2 out of 5
3103 NW 13th St, Gainesville, FL
$74 nightly
The price is $83 total per night from Nov 9 to Nov 10
$83 total
Nov 9 - Nov 10
Total with taxes and fees
Stay at this motel in Gainesville. Enjoy free WiFi, free parking, and room service. Popular attractions Ben Hill Griffin Stadium and Stephen C. O'Connell Center ...
6.2/10 (402 reviews)
Dated but clean.
Dated but clean, well maintained property. A bargain in Gainesville. Only negative, the flood lights in the parking lot bleed into the rooms despite blackout curtains. The strong light gives the impression the area is not safe. The area is safe. Tone down those lights.

Reviewed on Oct 20, 2025

Travelers Inn
Micanopy Inn

Micanopy Inn

2 out of 5
17110 SE County Road 234, Micanopy, FL
$45 nightly
The price is $51 total per night from Nov 9 to Nov 10
$51 total
Nov 9 - Nov 10
Total with taxes and fees
Stay at this motel in Micanopy. Enjoy daily housekeeping, laundry facilities, and premium TV channels. Popular attractions Micanopy Historical Society Museum ...
5/10 (457 reviews)
Good for the price

Reviewed on Jul 1, 2025

Micanopy Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Gainesville

Home2 Suites by Hilton Gainesville Medical Center

Home2 Suites by Hilton Gainesville Medical Center

3 out of 5
2115 Southwest 13th Street, Gainesville, FL
$99 nightly
The price is $112 total per night from Nov 30 to Dec 1
$112 total
Nov 30 - Dec 1
Total with taxes and fees
Stay at this 3-star business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (878 reviews)
Good. Easy.

Reviewed on Oct 26, 2025

Home2 Suites by Hilton Gainesville Medical Center
Homewood Suites by Hilton Gainesville

Homewood Suites by Hilton Gainesville

3 out of 5
3333 Sw 42nd St, Gainesville, FL
$98 nightly
The price is $111 total per night from Dec 4 to Dec 5
$111 total
Dec 4 - Dec 5
Total with taxes and fees
Stay at this 3-star business-friendly hotel in Gainesville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in ...
8.4/10 Very Good! (909 reviews)
The reception staff were so friendly. Always said a greeting entering or leaving the hotel. I had filled out a pet registration form and was very impressed when the receptionist greeted my dog by name. The hotel and room were very clean. There was a variety of breakfast food that would satisfy every ...

Reviewed on Oct 28, 2025

Homewood Suites by Hilton Gainesville
DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville

4 out of 5
3726 Sw 40th Blvd, Gainesville, FL
$89 nightly
The price is $101 total per night from Nov 13 to Nov 14
$101 total
Nov 13 - Nov 14
Total with taxes and fees
Stay at this 4-star hotel in Gainesville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
7.6/10 Good! (1,006 reviews)
Staff was great and so were the housekeeping girls.

Reviewed on Oct 28, 2025

DoubleTree by Hilton Gainesville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TYS to GNV Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York
GNV Address & GPS
Address:
3400 Northeast 39th Avenue
Gainesville FL, 32609
United States
IATA Code:
GNV
Longitude:
-82.276797
Latitude:
29.686142
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Knoxville Airport to GNV?
Flying from McGhee Tyson Airport (TYS) to GNV? Breaking up the journey is your one and only option as there are no carriers that service this route directly. However, American Airlines, Delta Air Lines and United Airlines offer the closest thing — a flight with just one stop.
What is the shortest flight from Knoxville Airport to GNV?
From Knoxville, the thrilling sights and sounds of Gainesville are 3 hours and 24 minutes away. Be sure to book your favorite seat, or maybe even one with extra legroom, and fly to your destination in total comfort.
How many hours flight from Knoxville Airport to GNV?
Typically, the flight time from Knoxville Airport to Gainesville Regional Airport (GNV) takes 3 hours and 31 minutes. If you want to be as comfy as possible, think about upgrading your seat using air miles or cash.
What airlines have the most flights from Knoxville Airport to Gainesville Regional Airport?
Do a bit of shopping, sit down for a coffee, go for a wander around .... Airport stopovers don't have to be something to dread! If you're jetting between Knoxville and Gainesville, you can't fly direct. Get ready to make a stop somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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