Cheap flights from TYS to GNV (McGhee Tyson to Gainesville Regional)

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Cheap Flights from TYS to GNV starting at $231 One Way, $317 Round Trip

Prices starting at $317 for return flights and $231 for one-way flights to Gainesville Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Apr 18 - Tue, Apr 21
TYS
Knoxville
GNV
Gainesville
$317 Roundtrip, found 23 hours ago
$317
Roundtrip
found 23 hours ago
Select Delta flight, departing Sat, Apr 18 from Knoxville to Gainesville, returning Tue, Apr 21, priced at $317 found 23 hours ago
Sat, Apr 18 - Mon, Apr 20
TYS
Knoxville
GNV
Gainesville
$337 Roundtrip, found 23 hours ago
$337
Roundtrip
found 23 hours ago
Select Delta flight, departing Sat, Apr 18 from Knoxville to Gainesville, returning Mon, Apr 20, priced at $337 found 23 hours ago
Tue, Apr 14 - Tue, Apr 21
TYS
Knoxville
GNV
Gainesville
$357 Roundtrip, found 23 hours ago
$357
Roundtrip
found 23 hours ago
Select Delta flight, departing Tue, Apr 14 from Knoxville to Gainesville, returning Tue, Apr 21, priced at $357 found 23 hours ago
Thu, Apr 16 - Tue, Apr 21
TYS
Knoxville
GNV
Gainesville
$360 Roundtrip, found 23 hours ago
$360
Roundtrip
found 23 hours ago
Select Delta flight, departing Thu, Apr 16 from Knoxville to Gainesville, returning Tue, Apr 21, priced at $360 found 23 hours ago
Tue, Apr 14 - Sat, Apr 18
TYS
Knoxville
GNV
Gainesville
$377 Roundtrip, found 23 hours ago
$377
Roundtrip
found 23 hours ago
Select Delta flight, departing Tue, Apr 14 from Knoxville to Gainesville, returning Sat, Apr 18, priced at $377 found 23 hours ago

Hotel Ideas near Gainesville Regional

Airport Hotels near Gainesville Regional

Home away from home

Home away from home

2 out of 5
Gainesville FL
$213 nightly
The price is $237 total per night from Feb 9 to Feb 10
$237 total
Feb 9 - Feb 10
Total with taxes and fees
Stay at this B&B in Gainesville. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Ben Hill Griffin Stadium and Ironwood Golf Course are ...
10/10 Exceptional! (2 reviews)
Wonderful place to stay! Lovely hosts and home. Great outdoor space!

Reviewed on Jan 21, 2026

Home away from home
Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown

3 out of 5
212 SE 1ST STREET, Gainesville FL
$110 nightly
The price is $123 total per night from Feb 15 to Feb 16
$123 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,122 reviews)
Room was great and the hotel was great. Great fun location with lots of restaurants and activity around. Staff was incredible as well. Only negative is parking. Limited street parking and overnight parking is $30 at the closest garage.

Reviewed on Feb 1, 2026

Hyatt Place Gainesville Downtown
Cheerful 4 bedroom house 8 min away from UF

Cheerful 4 bedroom house 8 min away from UF

Gainesville FL
$296 nightly
The price is $329 total per night from Feb 6 to Feb 7
$329 total
Feb 6 - Feb 7
Total with taxes and fees
Stay at this vacation home in Gainesville. Enjoy laundry facilities and air conditioning. Popular attractions Ben Hill Griffin Stadium and Matheson History Museum ...
8.8/10 Excellent! (9 reviews)
Great place, but previous guests must have put dirty dishes and cooking equipment away as we found the air fryer was gross and a few other items. They were in cabinets, so I am sure the cleaning crew didn't think to investigate it. Otherwise it was very clean. The only other negative was that the ...

Reviewed on Nov 21, 2025

Cheerful 4 bedroom house 8 min away from UF
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Gainesville

DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville

4 out of 5
3726 Sw 40th Blvd Gainesville FL
$93 nightly
The price is $104 total per night from Feb 11 to Feb 12
$104 total
Feb 11 - Feb 12
Total with taxes and fees
Stay at this hotel in Gainesville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,002 reviews)
👍

Reviewed on Jan 23, 2026

DoubleTree by Hilton Gainesville
Hotel Eleo at the University of Florida

Hotel Eleo at the University of Florida

3 out of 5
1514 Southwest 14th Street Gainesville FL
$179 nightly
The price is $201 total per night from Feb 9 to Feb 10
$201 total
Feb 9 - Feb 10
Total with taxes and fees
Stay at this hotel in Gainesville. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the helpful staff in our ...
9.2/10 Wonderful! (1,299 reviews)
Excellent

Reviewed on Feb 3, 2026

Hotel Eleo at the University of Florida
Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown

3 out of 5
212 SE 1ST STREET, Gainesville FL
$110 nightly
The price is $123 total per night from Feb 15 to Feb 16
$123 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,122 reviews)
Room was great and the hotel was great. Great fun location with lots of restaurants and activity around. Staff was incredible as well. Only negative is parking. Limited street parking and overnight parking is $30 at the closest garage.

Reviewed on Feb 1, 2026

Hyatt Place Gainesville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Gainesville Hotels With Airport Transportation

Best Western Gateway Grand

Best Western Gateway Grand

3 out of 5
4200 NW 97th Blvd Gainesville FL
$94 nightly
The price is $105 total per night from Feb 11 to Feb 12
$105 total
Feb 11 - Feb 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.6/10 Excellent! (1,411 reviews)
Friendly staff, clean hotel.

Reviewed on Jan 25, 2026

Best Western Gateway Grand
Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville

3.5 out of 5
1714 SW 34th St Gainesville FL
$114 nightly
The price is $128 total per night from Feb 15 to Feb 16
$128 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (1,002 reviews)
Very nice and clean hotel! Really Loved the personal text from Lauren asking how my check in was first night. Loved the food at their steakhouse restaurant.

Reviewed on Feb 1, 2026

Hilton University of Florida Conference Center Gainesville
Holiday Inn Gainesville - University Center by IHG

Holiday Inn Gainesville - University Center by IHG

3 out of 5
1250 W University Ave Gainesville FL
$99 nightly
The price is $111 total per night from Feb 8 to Feb 9
$111 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this golf hotel in Gainesville. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the room service ...
7.8/10 Good! (1,004 reviews)
Very clean, comfortable bed,easy walk to University of Florida

Reviewed on Jan 31, 2026

Holiday Inn Gainesville - University Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Gainesville Hotels

Super 8 by Wyndham Gainesville I-75 Hospital University Area

Super 8 by Wyndham Gainesville I-75 Hospital University Area

2 out of 5
4202 SW 40th Blvd Gainesville FL
$50 nightly
The price is $56 total per night from Feb 8 to Feb 9
$56 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (1,007 reviews)
Staff always helpful and polite.

Reviewed on Feb 1, 2026

Super 8 by Wyndham Gainesville I-75 Hospital University Area
Travelers Inn

Travelers Inn

2 out of 5
3103 NW 13th St Gainesville FL
$74 nightly
The price is $83 total per night from Feb 8 to Feb 9
$83 total
Feb 8 - Feb 9
Total with taxes and fees
Stay at this motel in Gainesville. Enjoy free WiFi, free parking, and room service. Popular attractions Ben Hill Griffin Stadium and Stephen C. O'Connell Center ...
6.2/10 (403 reviews)
The room was spotless, the doors were fishy xD but overall its good!

Reviewed on Feb 1, 2026

Travelers Inn
Micanopy Inn

Micanopy Inn

2 out of 5
17110 SE County Road 234 Micanopy FL
Stay at this motel in Micanopy. Enjoy daily housekeeping, laundry facilities, and premium TV channels. Popular attractions Micanopy Historical Society Museum ...
5/10 (463 reviews)
Staff very helpful

Reviewed on Jan 23, 2026

Get rates
Micanopy Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Gainesville

Home2 Suites by Hilton Gainesville Medical Center

Home2 Suites by Hilton Gainesville Medical Center

3 out of 5
2115 Southwest 13th Street Gainesville FL
$102 nightly
The price is $114 total per night from Feb 22 to Feb 23
$114 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (911 reviews)
Was a wonderful place, clean, spacious, comfortable

Reviewed on Jan 27, 2026

Home2 Suites by Hilton Gainesville Medical Center
Homewood Suites by Hilton Gainesville

Homewood Suites by Hilton Gainesville

3 out of 5
3333 Sw 42nd St Gainesville FL
$98 nightly
The price is $110 total per night from Feb 16 to Feb 17
$110 total
Feb 16 - Feb 17
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in ...
8.4/10 Very Good! (957 reviews)
Everything was great.

Reviewed on Jan 30, 2026

Homewood Suites by Hilton Gainesville
DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville

4 out of 5
3726 Sw 40th Blvd Gainesville FL
$93 nightly
The price is $104 total per night from Feb 11 to Feb 12
$104 total
Feb 11 - Feb 12
Total with taxes and fees
Stay at this hotel in Gainesville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,002 reviews)
👍

Reviewed on Jan 23, 2026

DoubleTree by Hilton Gainesville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TYS to GNV Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York
GNV Address & GPS
Address:
3400 Northeast 39th Avenue
Gainesville FL, 32609
United States
IATA Code:
GNV
Longitude:
-82.276797
Latitude:
29.686142
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Knoxville Airport to GNV?
Flying from McGhee Tyson Airport (TYS) to GNV? Breaking up the journey is your one and only option as there are no carriers that service this route directly. However, American Airlines, Delta Air Lines and United Airlines offer the closest thing — a flight with just one stop.
What is the shortest flight from Knoxville Airport to GNV?
From Knoxville, the thrilling sights and sounds of Gainesville are 3 hours and 24 minutes away. Be sure to book your favorite seat, or maybe even one with extra legroom, and fly to your destination in total comfort.
How many hours flight from Knoxville Airport to GNV?
Typically, the flight time from Knoxville Airport to Gainesville Regional Airport (GNV) takes 3 hours and 31 minutes. If you want to be as comfy as possible, think about upgrading your seat using air miles or cash.
What airlines have the most flights from Knoxville Airport to Gainesville Regional Airport?
Do a bit of shopping, sit down for a coffee, go for a wander around .... Airport stopovers don't have to be something to dread! If you're jetting between Knoxville and Gainesville, you can't fly direct. Get ready to make a stop somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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