Cheap flights from TYS to HOU (McGhee Tyson to William P. Hobby)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from TYS to HOU starting at $145 One Way, $289 Round Trip

Prices starting at $289 for return flights and $145 for one-way flights to William P. Hobby were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 29 - Wed, Sep 2
TYS
Knoxville
HOU
Houston
$289 Roundtrip, found 2 days ago
$289
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Aug 29 from Knoxville to Houston, returning Wed, Sep 2, priced at $289 found 2 days ago
Thu, Jun 18 - Mon, Jun 22
TYS
Knoxville
HOU
Houston
$306 Roundtrip, found 6 days ago
$306
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Jun 18 from Knoxville to Houston, returning Mon, Jun 22, priced at $306 found 6 days ago
Thu, Jun 18 - Mon, Jun 22
TYS
Knoxville
HOU
Houston
$311 Roundtrip, found 6 days ago
$311
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Thu, Jun 18 from Knoxville to Houston, returning Mon, Jun 22, priced at $311 found 6 days ago

Hotel Ideas near William P. Hobby

Airport Hotels near William P. Hobby

Best Western Plus Hobby Airport Inn & Suites

Best Western Plus Hobby Airport Inn & Suites

2.5 out of 5
8778 Airport Blvd Houston TX
$81 nightly
The price is $95 total per night from May 21 to May 22
$95 total
May 21 - May 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,554 reviews)
The room was clean. Breakfast was all gone when I got down there. Pool was cold and very dirty. Staff and hotel itself was nice, the rest could use some work.

Reviewed on May 14, 2026

Best Western Plus Hobby Airport Inn & Suites
Wyndham Houston Hobby Airport

Wyndham Houston Hobby Airport

3 out of 5
8611 Airport Blvd Houston TX
$55 nightly
The price is $64 total per night from May 28 to May 29
$64 total
May 28 - May 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
6.8/10 (1,000 reviews)
Not a good location we stayed here to have close access to the airport and they had huge roaches on the wall when we woke up

Reviewed on May 10, 2026

Wyndham Houston Hobby Airport
Houston Marriott South at Hobby Airport

Houston Marriott South at Hobby Airport

3.5 out of 5
9100 Gulf Fwy Houston TX
$95 nightly
The price is $111 total per night from May 24 to May 25
$111 total
May 24 - May 25
Total with taxes and fees
Book a stay at this family-friendly hotel in Houston. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,457 reviews)
Great stay

Reviewed on May 11, 2026

Houston Marriott South at Hobby Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Houston

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
$153 nightly
The price is $179 total per night from May 29 to May 30
$179 total
May 29 - May 30
Total with taxes and fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (4,013 reviews)
Hallways in upper floors need some updating. Fee to self park is pretty pricey.

Reviewed on May 14, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
$223 nightly
The price is $261 total per night from May 25 to May 26
$261 total
May 25 - May 26
Total with taxes and fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,002 reviews)
No breakfast instead a good coffee bar

Reviewed on May 12, 2026

Hotel Zaza Houston Museum District
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
$106 nightly
The price is $124 total per night from May 17 to May 18
$124 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (4,165 reviews)
I picked this hotel because it was cost-effective, but also had great reviews, and I cannot figure out where those great reviews came from. The fixtures in the rooms are very old… The shower grates are gross, there was rust on the bathroom door frame, and tiny fruit flies in the room. The furniture ...

Reviewed on May 13, 2026

Club Quarters Hotel Downtown, Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Houston Hotels With Airport Transportation

Ramada by Wyndham Houston Intercontinental Airport East

Ramada by Wyndham Houston Intercontinental Airport East

3.5 out of 5
6115 Will Clayton Parkway Humble TX
$67 nightly
The price is $78 total per night from May 17 to May 18
$78 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Humble. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the restaurant and the helpful staff ...
7.4/10 Good! (2,140 reviews)
Property feels and looks dated. Rotting wood trim on building, stained furniture in room, surfaces need pait, with updated colors, not pale yellow, hallway carpet stained and worn, lobby furniture stained.

Reviewed on May 11, 2026

Ramada by Wyndham Houston Intercontinental Airport East
La Quinta Inn & Suites by Wyndham Houston Bush Intl Airpt E

La Quinta Inn & Suites by Wyndham Houston Bush Intl Airpt E

3 out of 5
18201 Kenswick Drive Humble TX
$73 nightly
The price is $86 total per night from May 25 to May 26
$86 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Humble. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the clean rooms in our ...
7.8/10 Good! (2,426 reviews)
Friendly staff, clean, comfortable bed. It only about 5 minutes from IAH

Reviewed on May 13, 2026

La Quinta Inn & Suites by Wyndham Houston Bush Intl Airpt E
Days Inn by Wyndham Humble/Houston Intercontinental Airport

Days Inn by Wyndham Humble/Houston Intercontinental Airport

2.5 out of 5
9824 J M Hester Road Humble TX
$58 nightly
The price is $68 total per night from May 15 to May 16
$68 total
May 15 - May 16
Total with taxes and fees
Book a stay at this business-friendly motel in Humble. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the helpful staff and the ...
7.2/10 Good! (1,000 reviews)
No

Reviewed on May 9, 2026

Days Inn by Wyndham Humble/Houston Intercontinental Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Houston Hotels

Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
$106 nightly
The price is $124 total per night from May 17 to May 18
$124 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (4,165 reviews)
I picked this hotel because it was cost-effective, but also had great reviews, and I cannot figure out where those great reviews came from. The fixtures in the rooms are very old… The shower grates are gross, there was rust on the bathroom door frame, and tiny fruit flies in the room. The furniture ...

Reviewed on May 13, 2026

Club Quarters Hotel Downtown, Houston
Ramada by Wyndham Houston Intercontinental Airport East

Ramada by Wyndham Houston Intercontinental Airport East

3.5 out of 5
6115 Will Clayton Parkway Humble TX
$67 nightly
The price is $78 total per night from May 17 to May 18
$78 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Humble. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the restaurant and the helpful staff ...
7.4/10 Good! (2,140 reviews)
Property feels and looks dated. Rotting wood trim on building, stained furniture in room, surfaces need pait, with updated colors, not pale yellow, hallway carpet stained and worn, lobby furniture stained.

Reviewed on May 11, 2026

Ramada by Wyndham Houston Intercontinental Airport East
GreenTree Inn Houston IAH Airport

GreenTree Inn Houston IAH Airport

2 out of 5
15675 John F. Kennedy Blvd Houston TX
$55 nightly
The price is $64 total per night from May 15 to May 16
$64 total
May 15 - May 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,130 reviews)
Clean room

Reviewed on May 11, 2026

GreenTree Inn Houston IAH Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Houston

SpringHill Suites Houston Medical Center/NRG Park

SpringHill Suites Houston Medical Center/NRG Park

3 out of 5
1400 Old Spanish Trl Houston TX
$114 nightly
The price is $133 total per night from May 29 to May 30
$133 total
May 29 - May 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,001 reviews)
Clean quiet

Reviewed on Apr 29, 2026

SpringHill Suites Houston Medical Center/NRG Park
The Woodlands Resort, Curio Collection by Hilton

The Woodlands Resort, Curio Collection by Hilton

4 out of 5
2301 North Millbend Drive The Woodlands TX
$206 nightly
The price is $237 total per night from May 25 to May 26
$237 total
May 25 - May 26
Total with taxes and fees
Book a stay at this golf resort in The Woodlands. Enjoy free WiFi, 2 outdoor pools, and 4 restaurants. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,001 reviews)

Families like: Outdoor pools, waterslide, game room, bicycle rentals

Travelers say...
Great

Reviewed on May 13, 2026

The Woodlands Resort, Curio Collection by Hilton
SpringHill Suites by Marriott Houston NASA/Webster

SpringHill Suites by Marriott Houston NASA/Webster

3 out of 5
1101 Magnolia Street Webster TX
$98 nightly
The price is $115 total per night from May 31 to Jun 1
$115 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Webster. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,000 reviews)
Very clean hotel . Nice staff

Reviewed on May 11, 2026

SpringHill Suites by Marriott Houston NASA/Webster
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TYS to HOU Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York
HOU Address & GPS
Address:
7800 Airport Boulevard
Houston TX, 77061
United States
IATA Code:
HOU
Longitude:
-95.277018
Latitude:
29.654513
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from McGhee Tyson Airport (TYS) to William P. Hobby Airport?
While you can't fly nonstop from Knoxville Airport to William P. Hobby Airport (HOU) at this point in time, there are a number of air carriers that operate on this route with just one stopover. Why not check if the dates and times available with Delta Air Lines or American Airlines match your travel plans? If not, check out Frontier Airlines.
What is the shortest flight from Knoxville Airport to William P. Hobby Airport (HOU)?
The shortest flight from TYS to William P. Hobby Airport (HOU) is 4 hours and 20 minutes. Bring something on board to keep you occupied, like the latest edition of your favorite magazine or a sketch pad.
How many hours flight from Knoxville Airport to William P. Hobby Airport?
Settle in and get comfy, because the average flight time from TYS to William P. Hobby Airport is 4 hours and 29 minutes. Watch a movie or two, get stuck into that book ... You'll have ample time to sit back and relax.
What airlines have the most flights from Knoxville Airport to William P. Hobby Airport (HOU)?
Do a bit of shopping, tuck into some takeaway, chat with a stranger ... Airport stopovers don't have to be something to dread! If you're jetting from TYS to HOU, you can't fly direct. Be prepared to make at least one stop somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore