Cheap flights from TYS to GNV (McGhee Tyson to Gainesville Regional)

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Cheap Flights from TYS to GNV starting at $215 One Way, $524 Round Trip

Prices starting at $524 for return flights and $215 for one-way flights to Gainesville Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Jul 30 - Thu, Aug 6
TYS
Knoxville
GNV
Gainesville
$524 Roundtrip, found 3 days ago
$524
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Jul 30 from Knoxville to Gainesville, returning Thu, Aug 6, priced at $524 found 3 days ago
Thu, Jul 30 - Thu, Aug 6
TYS
Knoxville
GNV
Gainesville
$529 Roundtrip, found 3 days ago
$529
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Jul 30 from Knoxville to Gainesville, returning Thu, Aug 6, priced at $529 found 3 days ago
Thu, Jul 30 - Thu, Aug 6
TYS
Knoxville
GNV
Gainesville
$550 Roundtrip, found 3 days ago
$550
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Jul 30 from Knoxville to Gainesville, returning Thu, Aug 6, priced at $550 found 3 days ago
Thu, Jul 30 - Thu, Aug 6
TYS
Knoxville
GNV
Gainesville
$576 Roundtrip, found 3 days ago
$576
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Jul 30 from Knoxville to Gainesville, returning Thu, Aug 6, priced at $576 found 3 days ago
Thu, Jul 30 - Thu, Aug 6
TYS
Knoxville
GNV
Gainesville
$585 Roundtrip, found 3 days ago
$585
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Jul 30 from Knoxville to Gainesville, returning Thu, Aug 6, priced at $585 found 3 days ago

Hotel Ideas near Gainesville Regional

Airport Hotels near Gainesville Regional

Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown

3 out of 5
212 SE 1ST STREET, Gainesville FL
$110 nightly
The price is $124 total per night from Jul 31 to Aug 1
$124 total
Jul 31 - Aug 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,203 reviews)
"We love staying there whenever we do a long drive and Gainesville is on the way. The staff is always super nice, we love the location and how walkable it is. The rooms are nice and clean, love that there is no carpet in it. It could get loud at times, there’s a bar across the hotel for college students ..."

Reviewed on Jul 24, 2026

Hyatt Place Gainesville Downtown
Sweetwater Branch Inn

Sweetwater Branch Inn

3.5 out of 5
625 East University Avenue Gainesville FL
$138 nightly
The price is $155 total per night from Jul 31 to Aug 1
$155 total
Jul 31 - Aug 1
Total with taxes and fees
Stay at this B&B in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Sweetwater Branch Inn
Underwater Home w/Game Room ~6 min to Stadium & DT

Underwater Home w/Game Room ~6 min to Stadium & DT

Gainesville FL
$292 nightly
The price is $305 total per night from Jul 28 to Jul 29
$305 total
Jul 28 - Jul 29
Total with taxes and fees
Book a stay at this family-friendly vacation home in Gainesville. Enjoy a garden, laundry facilities, and a pool table. Popular attractions Ben Hill Griffin ...
10/10 Exceptional! (11 reviews)
"Enjoyed pool table"

Reviewed on Jun 15, 2026

Underwater Home w/Game Room ~6 min to Stadium & DT
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Gainesville

HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western

2.5 out of 5
3905 Sw 43Rd St Gainesville FL
$80 nightly
The price is $90 total per night from Aug 2 to Aug 3
$90 total
Aug 2 - Aug 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
HOM Hotel Gainesville, SureStay Collection by Best Western
Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands

2.5 out of 5
4110 SW 40th Boulevard Gainesville FL
$82 nightly
The price is $92 total per night from Aug 18 to Aug 19
$92 total
Aug 18 - Aug 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Sleep Inn & Suites University/Shands
Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville

3.5 out of 5
1714 SW 34th St Gainesville FL
$98 nightly
The price is $110 total per night from Aug 2 to Aug 3
$110 total
Aug 2 - Aug 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,020 reviews)
"Lobby is nice. Rooms need touch up."

Reviewed on Jul 24, 2026

Hilton University of Florida Conference Center Gainesville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Gainesville Hotels With Airport Transportation

Best Western Gateway Grand

Best Western Gateway Grand

3 out of 5
4200 NW 97th Blvd Gainesville FL
$84 nightly
The price is $95 total per night from Aug 2 to Aug 3
$95 total
Aug 2 - Aug 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.6/10 Excellent! (1,514 reviews)
"Amazing"

Reviewed on Jul 24, 2026

Best Western Gateway Grand
Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville

3.5 out of 5
1714 SW 34th St Gainesville FL
$98 nightly
The price is $110 total per night from Aug 2 to Aug 3
$110 total
Aug 2 - Aug 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,020 reviews)
"Lobby is nice. Rooms need touch up."

Reviewed on Jul 24, 2026

Hilton University of Florida Conference Center Gainesville
Holiday Inn Gainesville - University Center by IHG

Holiday Inn Gainesville - University Center by IHG

3 out of 5
1250 W University Ave Gainesville FL
$95 nightly
The price is $107 total per night from Jul 29 to Jul 30
$107 total
Jul 29 - Jul 30
Total with taxes and fees
Book a stay at this golf hotel in Gainesville. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff and the ...
8/10 Very Good! (1,001 reviews)
"Very clean rooms, breakfast was very good and very helpful staff"

Reviewed on Jul 22, 2026

Holiday Inn Gainesville - University Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Gainesville Hotels

Super 8 by Wyndham Gainesville I-75 Hospital University Area

Super 8 by Wyndham Gainesville I-75 Hospital University Area

2 out of 5
4202 SW 40th Blvd Gainesville FL
$50 nightly
The price is $56 total per night from Aug 23 to Aug 24
$56 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,046 reviews)
"The hotel has been renovated. It has microwave, security box and small refrigerator.. The light in the room as poor... because the rate is low, customers are mainly workers that need overnight and are noisy.."

Reviewed on Jul 24, 2026

Super 8 by Wyndham Gainesville I-75 Hospital University Area
Travelers Inn

Travelers Inn

2 out of 5
3103 NW 13th St Gainesville FL
$54 nightly
The price is $61 total per night from Jul 26 to Jul 27
$61 total
Jul 26 - Jul 27
Total with taxes and fees
Stay at this motel in Gainesville. Enjoy free WiFi, free parking, and room service. Popular attractions Ben Hill Griffin Stadium and Thomas Center are located ...
6.4/10 (410 reviews)
"better than expected, good access to stadium"

Reviewed on May 26, 2026

Travelers Inn
Micanopy Inn

Micanopy Inn

2 out of 5
17110 SE County Road 234 Micanopy FL
$36 nightly
The price is $41 total per night from Jul 26 to Jul 27
$41 total
Jul 26 - Jul 27
Total with taxes and fees
Stay at this motel in Micanopy. Enjoy daily housekeeping, laundry facilities, and premium TV channels. Popular attractions Micanopy Historical Society Museum ...
5.2/10 (463 reviews)
"Staff very helpful"

Reviewed on Jan 23, 2026

Micanopy Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Gainesville

Home2 Suites by Hilton Gainesville Medical Center

Home2 Suites by Hilton Gainesville Medical Center

3 out of 5
2115 Southwest 13th Street Gainesville FL
$102 nightly
The price is $114 total per night from Aug 2 to Aug 3
$114 total
Aug 2 - Aug 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our ...
Home2 Suites by Hilton Gainesville Medical Center
Homewood Suites by Hilton Gainesville

Homewood Suites by Hilton Gainesville

3 out of 5
3333 Sw 42nd St Gainesville FL
$102 nightly
The price is $114 total per night from Aug 23 to Aug 24
$114 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in ...
8.6/10 Excellent! (1,002 reviews)
"Great"

Reviewed on Jul 25, 2026

Homewood Suites by Hilton Gainesville
DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville

4 out of 5
3726 Sw 40th Blvd Gainesville FL
$85 nightly
The price is $96 total per night from Aug 1 to Aug 2
$96 total
Aug 1 - Aug 2
Total with taxes and fees
Stay at this hotel in Gainesville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,003 reviews)
"Great locación.. onsite bar restaurant. Only concern ground floor room/flooring seemed damp."

Reviewed on Jul 22, 2026

DoubleTree by Hilton Gainesville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TYS to GNV Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York
GNV Address & GPS
Address:
3400 Northeast 39th Avenue
Gainesville FL, 32609
United States
IATA Code:
GNV
Longitude:
-82.276797
Latitude:
29.686142
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Knoxville Airport to GNV?
Flying from McGhee Tyson Airport (TYS) to GNV? Breaking up the journey is your one and only option as there are no carriers that service this route directly. However, American Airlines, Delta Air Lines and United Airlines offer the closest thing — a flight with just one stop.
What is the shortest flight from Knoxville Airport to GNV?
From Knoxville, the thrilling sights and sounds of Gainesville are 3 hours and 24 minutes away. Be sure to book your favorite seat, or maybe even one with extra legroom, and fly to your destination in total comfort.
How many hours flight from Knoxville Airport to GNV?
Typically, the flight time from Knoxville Airport to Gainesville Regional Airport (GNV) takes 3 hours and 31 minutes. If you want to be as comfy as possible, think about upgrading your seat using air miles or cash.
What airlines have the most flights from Knoxville Airport to Gainesville Regional Airport?
Do a bit of shopping, sit down for a coffee, go for a wander around .... Airport stopovers don't have to be something to dread! If you're jetting between Knoxville and Gainesville, you can't fly direct. Get ready to make a stop somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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