The Chemists’ Club Hotel

4.0 star property

Choose dates to view prices

Photo gallery for The Chemists’ Club Hotel

Deluxe Room, 1 Queen Bed, Terrace | Down comforters, in-room safe, desk, laptop workspace
Interior
Interior
Exterior
Restaurant

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Free WiFi
  • Air conditioning
  • Bar
  • Laundry

Explore the area

View in a map
52 E 41st St, New York, NY, 10017
  • Place, 5th Avenue
    ‪3 min walk‬
  • Place, Grand Central Terminal
    ‪3 min walk‬
  • Place, Bryant Park
    ‪5 min walk‬
  • Airport, Newark Liberty Intl. Airport (EWR)
    ‪29 min drive‬

Room options

Classic Room, 1 King Bed

9.8 out of 10
Exceptional
(17 reviews)
  • 200 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 King Bed

9.6 out of 10
Exceptional
(35 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Queen Bed

10.0 out of 10
Exceptional
(1 review)
  • 200 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed

Deluxe Room, 2 Double Beds

10.0 out of 10
Exceptional
(3 reviews)
  • 350 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds

Deluxe Double Mobility/Hearing Accessible with Roll-In Shower

10.0 out of 10
Exceptional
(3 reviews)
  • 350 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds

King Deluxe Mobility/Hearing Accessible with Roll-In Shower

10.0 out of 10
Exceptional
(1 review)
  • 350 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

Junior Suite

8.8 out of 10
Excellent
(8 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

Deluxe Room, 1 Queen Bed, Terrace

  • 200 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed

Junior Suite King Mobility/Hearing Accessible with Transfer Shower

  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

Alchemy Suite

10.0 out of 10
Exceptional
(1 review)
  • 350 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

King Deluxe Mobility/Hearing Accessible with Tub

  • Sleeps 2
  • 1 King Bed

You may also like

About the neighborhood

New York

Located in Manhattan, The Chemists’ Club Hotel is within a 5-minute walk of popular attractions such as Grand Central Terminal and 5th Avenue. This 107-room, 4-star hotel welcomes guests with a restaurant, a 24-hour gym, and free in-room WiFi.

What's nearby

  • 5th Avenue - 3 min walk - 0.2 miles
  • Grand Central Terminal - 3 min walk - 0.2 miles
  • Bryant Park - 5 min walk - 0.3 miles
  • Empire State Building - 8 min walk - 0.5 miles
  • Times Square - 11 min walk - 0.6 miles

Getting around

  • Grand Central - 42 St. Station - 2 min walk
  • 5 Av Station (W. 42nd St.) - 4 min walk
  • LaGuardia Airport (LGA) - 28 min drive

Restaurants

  • ‪Après - ‬3 min walk
  • ‪Chick-fil-A - ‬2 min walk
  • ‪Pershing Square - ‬2 min walk
  • ‪Los Tacos No. 1 - ‬2 min walk
  • ‪Tartinery Café - Bar | Park Ave - ‬2 min walk

About this property

The Chemists’ Club Hotel

Guests of The Chemists’ Club Hotel enjoy features like a 24-hour gym, free WiFi in public areas, and free newspapers. The 24-hour front desk has multilingual staff ready to assist with concierge services and dry cleaning/laundry. This boutique hotel also has laundry facilities.
Guests can expect free WiFi and 55-inch LED TVs with cable channels. Bathrooms offer hair dryers and designer toiletries, and beds sport down comforters. Refrigerators, coffee makers, and free weekday newspapers are other standard amenities.
Recreational amenities at the hotel include a 24-hour fitness center.

The recreational activities listed below are available either on site or nearby; fees may apply.

Similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Offsite parking within 0.2 miles (USD 65 per day)

Food and drink

  • A bar/lounge
  • A restaurant

Things to do

  • 24-hour gym

Family friendly

  • In-room crib
  • In-room refrigerator
  • Laundry facilities
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities

Guest services

  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Multilingual staff
  • Tour and ticket assistance

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Accessible bathtub
  • Assistive listening devices
  • Bathroom emergency pull cord
  • Braille/raised signage
  • Elevator
  • Wheelchair accessible (may have limitations)

More

  • 16 floors
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Down comforter
  • Free crib

Bathroom

  • Bathrobes
  • Bathtub or shower
  • Designer toiletries
  • Hair dryer
  • Private bathroom
  • Slippers
  • Towels provided

Entertainment

  • 55-inch LED TV with cable channels

Food and drink

  • Coffee/tea maker
  • Electric kettle
  • Limited room service
  • Refrigerator

More

  • Air conditioning
  • Desk
  • Desk chair
  • Free weekday newspapers
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: anytime
Early check-in subject to availability
Early check-in fee: USD 60.00
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Late check-out subject to availability
Late check-out fee: USD 150

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Service animals exempt from fees

Children and extra beds

  • Up to 10 kids 1 year old and younger stay free when using existing bedding
  • Free cribs/infant beds are available

Property payment types

Important information

Fees

You'll be asked to pay these charges at the property:

  • Deposit: USD 50.00 per night
  • Destination fee: USD 40.17 per accommodation, per night

These are all of the charges provided to us by the property.

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Offsite parking fee: USD 65 per day (0.2 mi away)
  • Early check-in fee: USD 60.00 (subject to availability)
  • Late check-out fee: USD 150 (subject to availability)

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and cash
Noise-free guestrooms cannot be guaranteed
Safety features at this property include a fire extinguisher
  • Check-in: 3 PM
  • Check-out: 11 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A credit card for incidental charges and a government-issued photo ID may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards and cash.
  • The credit card used at check-in for incidentals must be in the name of the primary guest who made the reservation.
  • Onsite safety features include a fire extinguisher.

Additional information about polices, regulations, and more:

  • The hotel can refuse certain bookings for the purpose of group events or parties, which include pre-wedding stag/bachelor and hen/bachelorette parties.
  • Registered guests are the only ones allowed in guestrooms.
  • Noise-free rooms can't be guaranteed.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Dylan Hotel NYC New York
Dylan Hotel New York
Dylan New York
Hotel Dylan
Dylan Hotel New York City
Dylan New York City
Dylan NYC New York
Dylan NYC
Dylan Hotel NYC
The Chemists’ Club Hotel Hotel
The Chemists’ Club Hotel New York
The Chemists’ Club Hotel Hotel New York

Frequently asked questions

Is free cancellation available at The Chemists’ Club Hotel?

The Chemists’ Club Hotel offers free cancellation on select room rates. For additional details, review the cancellation policy on Orbitz.

How much does it cost to stay at The Chemists’ Club Hotel?

As of Mar 17, 2026, prices found for a 1-night stay for 2 adults at The Chemists’ Club Hotel on Mar 28, 2026 start from $416, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What can I see close to The Chemists’ Club Hotel?

This hotel is situated in Manhattan, just steps from Grand Central Terminal, and within a 10-minute walk of 5th Avenue and Bryant Park. You'll also find Rockefeller Center and Broadway less than a mile away.

Is parking available on site at The Chemists’ Club Hotel?

No, this hotel doesn't offer parking.

Does The Chemists’ Club Hotel feature a casino at the property?

No, The Chemists’ Club Hotel doesn't have a casino.

Is there an indoor pool at The Chemists’ Club Hotel?

No, there is no indoor pool at this hotel.

Is The Chemists’ Club Hotel a good place to stay for couples?

Amenities that appeal to couples at this boutique hotel include a down comforter, bathrobes, and slippers.

Are there hot tubs at The Chemists’ Club Hotel?

No, this hotel doesn't have a spa tub.

Does The Chemists’ Club Hotel have a restaurant with a breakfast menu?

No, The Chemists’ Club Hotel doesn't have a restaurant that serves breakfast.

Does The Chemists’ Club Hotel allow pets to stay free of charge?

No, pets aren't allowed at The Chemists’ Club Hotel though service animals are welcome.

Are there connecting rooms at The Chemists’ Club Hotel?

No, there aren't connecting guestrooms at this hotel.

How far is the airport from The Chemists’ Club Hotel?

The closest major airport to The Chemists’ Club Hotel is LaGuardia Airport (LGA), which is 9.4 mi away (28 minutes by car). Another top airport is Teterboro, NJ (TEB), which is located 12.6 mi away (20-minute drive).

Are there rooms with balconies that I can book at The Chemists’ Club Hotel?

No, there aren't any guestrooms with balconies at The Chemists’ Club Hotel.

The Chemists’ Club Hotel Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 282 out of 354 reviews
Rating 8 - Good. 49 out of 354 reviews
Rating 6 - Okay. 13 out of 354 reviews
Rating 4 - Poor. 3 out of 354 reviews
Rating 2 - Terrible. 7 out of 354 reviews

9.8/10

Cleanliness

9.6/10

Staff & service

9.4/10

Amenities

9.6/10

Property conditions & facilities

Reviews

10/10 Excellent

Andreina

Stayed 1 night in Nov 2025

10/10 Excellent

Douglas, Cape Porpoise

Liked: Cleanliness, amenities, property conditions & facilities
This is a hidden gem just off Bryant Park. The rooms and the staff are magnificent. Great location too.
Stayed 1 night in Dec 2025

10/10 Excellent

Erica

Liked: Cleanliness, staff & service, property conditions & facilities
Excellent staff!
Stayed 1 night in Dec 2025

10/10 Excellent

Lisa

Liked: Cleanliness, amenities, property conditions & facilities
Nice room, helpful staff, great location, we loved it!
Stayed 2 nights in Dec 2025

10/10 Excellent

Kimberly

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
The room was great, hotel spotless and beautiful - if not breathtaking. But the most important part was the personnel. The young lady at the front desk for check out was friendly, helpful and went out of her way to be both. Merry Christmas to All!
Stayed 1 night in Dec 2025

10/10 Excellent

Robert

Liked: Cleanliness, amenities, property conditions & facilities
Great location and staff!
Stayed 2 nights in Dec 2025

10/10 Excellent

Jason, Waxahachie

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
This hotel was an absolute gem. Beautifully appointed, quiet, clean and friendly staff. I plan to stay here for future trips to the city.
Stayed 3 nights in Dec 2025

8/10 Good

Angie

Stayed 3 nights in Oct 2025

10/10 Excellent

Sasa

Stayed 1 night in Nov 2025

10/10 Excellent

Troy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Beautiful and clean, like staying at your own place. Probably the softest bedding I have ever slept in. Right next to Grand Central but still a quiet apartment feel.
Stayed 1 night in Nov 2025

10/10 Excellent

Sasa

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Fabulous staff , amenities and quality of service
Stayed 1 night in Nov 2025

10/10 Excellent

Sasa

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Fabulous stay , excellent room cleanliness , amenities and staff friendliness
Stayed 1 night in Nov 2025

6/10 Okay

Todd

Liked: Cleanliness, staff & service
Walls are thin, mattresses are sagging, and the fixtures in the bathroom were loose and need updating. My rating reflects the relatively high price this hotel charges for their rooms. At this price point, expectations are higher. Other than these factors, this hotel has huge potential, very classy lobby, nice design, great building history and pedigree.
Stayed 2 nights in Nov 2025

10/10 Excellent

Michael, Glen Allen

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
We are seasoned travelers and loved our stay at the Chemists' Club hotel. The hotel is well located, the front desk staff is exceptional, and the room furnishing were high end and comfortable. The bathroom was on the small side, but manageable. We look forward to visiting again in the future.
Stayed 1 night in Jul 2025

10/10 Excellent

Kevin

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Clean rooms, nice welcome basket, concierge and staff were all super friendly and helpful. Excellent location. Gym was clean with equipment in good condition. A high level experience that will definitely see us come back in the future.
Stayed 2 nights in Nov 2025

8/10 Good

Silvia

Stayed 1 night in Nov 2025

10/10 Excellent

Aida

Traveled with group
Liked: Cleanliness, staff & service, amenities
We had a great stay at the Chemist Club Hotel. The Hotel itself is beautiful , clean and the rooms are large updated with comfortable bedding . The staff was kind, courteous and helpful . 5 star VIP treatment by staff with every interaction. The location is top tier ! Around the corner from Grand Central , situated between Park & Lexington and short walk to Bryant Park and subway lines. 5th Avenue 2 blocks away ! Overall I highly recommend The Chemist Club Hotel and any future trips I will definitely stay there again.
Stayed 1 night in Nov 2025

8/10 Good

Lourdes

Liked: Cleanliness, staff & service, property conditions & facilities
Enjoyed our stay at
Stayed 3 nights in Nov 2025

6/10 Okay

Annette

Stayed 1 night in Nov 2025

10/10 Excellent

Stephen, New York

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
An elegant property with large and comfortable rooms that felt like a return to Old World elegance. The bed was fantastic. A wonderful addition to the NYC Midtown hotel scene.
Stayed 1 night in Nov 2025

10/10 Excellent

Angela

Business traveler
Liked: Cleanliness, staff & service, amenities
Great decor and very comfy bed! Definitely want to come back.
Stayed 1 night in Nov 2025

10/10 Excellent

Brian, Los Angeles

Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
My new favorite hotel in New York. I can’t wait to stay here again. Definitely recommend
Stayed 3 nights in Nov 2025

8/10 Good

Deborah

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Would be great if coffee was set up in lobby
Stayed 2 nights in Nov 2025

10/10 Excellent

Steven Lee

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Wonderful stay at The Chemists Club, beautiful hotel and staff were excellent.
Stayed 4 nights in Nov 2025

10/10 Excellent

Eva

Traveled with partner
Liked: Cleanliness, property conditions & facilities
The property itself is wonderful, after a long day of running around the city I was super pleased to find that my room was very comfortable! The area around the hotel was quiet which is new for me when staying in NYC. Staff was nice as well! I had a short stay so I didn’t get a chance to check out any amenities but the room quality & proximity to grand central were enough for me to be very happy with my stay.
Stayed 1 night in Oct 2025