Cheap flights from MFR to SFO (Rogue Valley Intl. to San Francisco Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from MFR to SFO starting at $130 One Way, $249 Round Trip

Prices starting at $249 for return flights and $130 for one-way flights to San Francisco Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Aug 18 - Sun, Aug 23
MFR
Medford
SFO
San Francisco
$249 Roundtrip, found 9 hours ago
$249
Roundtrip
found 9 hours ago
Select United flight, departing Tue, Aug 18 from Medford to San Francisco, returning Sun, Aug 23, priced at $249 found 9 hours ago
Fri, Jul 3 - Sun, Jul 5
MFR
Medford
SFO
San Francisco
$255 Roundtrip, found 1 day ago
$255
Roundtrip
found 1 day ago
Select United flight, departing Fri, Jul 3 from Medford to San Francisco, returning Sun, Jul 5, priced at $255 found 1 day ago
Fri, Oct 2 - Tue, Oct 13
MFR
Medford
SFO
San Francisco
$259 Roundtrip, found 9 hours ago
$259
Roundtrip
found 9 hours ago
Select Alaska Airlines flight, departing Fri, Oct 2 from Medford to San Francisco, returning Tue, Oct 13, priced at $259 found 9 hours ago
Thu, May 28 - Mon, Jun 1
MFR
Medford
SFO
San Francisco
$271 Roundtrip, found 6 days ago
$271
Roundtrip
found 6 days ago
Select Bargain Flight flight, departing Thu, May 28 from Medford to San Francisco, returning Mon, Jun 1, priced at $271 found 6 days ago
Wed, May 27 - Sun, May 31
MFR
Medford
SFO
San Francisco
$280 Roundtrip, found 4 days ago
$280
Roundtrip
found 4 days ago
Select Bargain Flight flight, departing Wed, May 27 from Medford to San Francisco, returning Sun, May 31, priced at $280 found 4 days ago

Hotel Ideas near San Francisco Intl.

Airport Hotels near San Francisco Intl.

Grand Hyatt at SFO

Grand Hyatt at SFO

4 out of 5
55 S McDonnell Rd San Francisco CA
$309 nightly
The price is $345 total per night from May 26 to May 27
$345 total
May 26 - May 27
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the restaurant ...
9.8/10 Exceptional! (1,595 reviews)
"Super convenient for SFO. Good restaurant."

Reviewed on May 22, 2026

Grand Hyatt at SFO
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
1550 Bayshore Hwy Burlingame CA
$185 nightly
The price is $209 total per night from May 29 to May 30
$209 total
May 29 - May 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (4,882 reviews)
"Clean room, amazing waterfront view, buffet breakfast, free onsite parking"

Reviewed on May 25, 2026

Bay Landing San Francisco Airport Hotel
Crowne Plaza San Francisco Airport by IHG

Crowne Plaza San Francisco Airport by IHG

3.5 out of 5
1177 Airport Blvd Burlingame CA
$105 nightly
The price is $119 total per night from May 31 to Jun 1
$119 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Burlingame. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and the clean ...
Crowne Plaza San Francisco Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Francisco

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
$201 nightly
The price is $237 total per night from May 26 to May 27
$237 total
May 26 - May 27
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,501 reviews)
"Breakfast was great"

Reviewed on May 25, 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
$111 nightly
The price is $131 total per night from May 31 to Jun 1
$131 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.8/10 Excellent! (2,801 reviews)
"The room was clean. the staff was friendly. breakfast was okay. air conditioning worked fine. I thought that all the rooms had microwave ovens but my room did not have microwave oven which I missed using to warm up my leftovers from the days of dining out."

Reviewed on May 25, 2026

Hilton San Francisco Financial District
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
$140 nightly
The price is $165 total per night from May 26 to May 27
$165 total
May 26 - May 27
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9/10 Wonderful! (5,794 reviews)
"Room was nice and clean."

Reviewed on May 25, 2026

Holiday Inn Golden Gateway by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Francisco Hotels With Airport Transportation

The Dylan at SFO

The Dylan at SFO

3 out of 5
110 S El Camino Real Millbrae CA
$131 nightly
The price is $155 total per night from May 30 to May 31
$155 total
May 30 - May 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Millbrae. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,875 reviews)
"Very close to the airport. Clean, affordable, great place to stay!"

Reviewed on May 24, 2026

The Dylan at SFO
Hotel Skye SFO

Hotel Skye SFO

3 out of 5
421 El Camino Real San Bruno CA
$124 nightly
The price is $142 total per night from May 31 to Jun 1
$142 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in San Bruno. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,778 reviews)
"Great stay and great location. Staff were friendly and helpful. Hotel is quiet and kept really clean. Would definitely stay here again!"

Reviewed on May 24, 2026

Hotel Skye SFO
Sfo El Rancho Inn

Sfo El Rancho Inn

3 out of 5
1100 El Camino Real Millbrae CA
Book a stay at this business-friendly hotel in Millbrae. Enjoy free breakfast, an outdoor pool, and a 24-hour fitness center. Our guests praise the breakfast ...
8.4/10 Very Good! (3,048 reviews)
"It feels like staying in a cheap motel."

Reviewed on May 4, 2026

Get rates
Sfo El Rancho Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Francisco Hotels

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

2 out of 5
326 S Airport Blvd South San Francisco CA
$69 nightly
The price is $82 total per night from May 31 to Jun 1
$82 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly motel in South San Francisco. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the clean ...
6/10 (3,651 reviews)
"I arrived about 2:30 PM. I was told that I would have to wait until 3:00 PM. This hotel posts quite plainly that check-in begins at 3:00 PM. When I got into the room, it was VERY MUSTY. The front desk was NOT holding the room until 3:00 PM to make sure that the room was in good condition for the ..."

Reviewed on May 24, 2026

Travelodge by Wyndham San Francisco Airport North
Hotel North Beach

Hotel North Beach

2 out of 5
935 Kearny Street San Francisco CA
$59 nightly
The price is $69 total per night from May 26 to May 27
$69 total
May 26 - May 27
Total with taxes and fees
Stay at this hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and laundry facilities. Our guests praise the helpful staff and the clean rooms in ...
7.2/10 Good! (1,004 reviews)
"Great location in the heart of North Beach/Chinatown. Historic building well maintained. Very clean and comfortable bed"

Reviewed on May 20, 2026

Hotel North Beach
Hotel Skye SFO

Hotel Skye SFO

3 out of 5
421 El Camino Real San Bruno CA
$124 nightly
The price is $142 total per night from May 31 to Jun 1
$142 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in San Bruno. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,778 reviews)
"Great stay and great location. Staff were friendly and helpful. Hotel is quiet and kept really clean. Would definitely stay here again!"

Reviewed on May 24, 2026

Hotel Skye SFO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Francisco

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

4 out of 5
250 Beach Street San Francisco CA
$178 nightly
The price is $209 total per night from May 28 to May 29
$209 total
May 28 - May 29
Total with taxes and fees
Book a stay at this boutique hotel in San Francisco. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (2,593 reviews)
"It is unpleasant to receive two vouchers for a mediocre breakfast at a restaurant where it is evident that one is not welcome—unless, that is, one orders from the regular menu. Regrettably, the poor service is quite noticeable."

Reviewed on May 24, 2026

Hotel Zephyr San Francisco
Embassy Suites by Hilton San Francisco Airport Waterfront

Embassy Suites by Hilton San Francisco Airport Waterfront

3.5 out of 5
150 Anza Blvd Burlingame CA
$139 nightly
The price is $158 total per night from Jun 5 to Jun 6
$158 total
Jun 5 - Jun 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Burlingame. Enjoy free breakfast, WiFi (surcharge), and parking (surcharge). Our guests praise the breakfast and ...
8.6/10 Excellent! (2,134 reviews)
"Staff kind, room so clean it smelled of cleaning products, breakfast delicious when you finally got to the front of the line, parking good. We always stay at the hotel when we’re in the area but this time it was very loud til 11:30 pm."

Reviewed on May 25, 2026

Embassy Suites by Hilton San Francisco Airport Waterfront
Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point

3.5 out of 5
250 Gateway Blvd South San Francisco CA
$143 nightly
The price is $168 total per night from May 31 to Jun 1
$168 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, a 24-hour fitness center, and parking (surcharge). Our guests praise ...
8.8/10 Excellent! (1,439 reviews)
"Property is in great location, and its nice hotel..love the whole place and staff specially the front desk are very helpful. We felt welcomed and at home"

Reviewed on May 25, 2026

Embassy Suites by Hilton San Francisco Airport Oyster Point
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MFR to SFO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MFR Address & GPS
Address:
1000 Terminal Spur Rd.
Medford OR, 97504
United States
IATA Code:
MFR
Longitude:
-122.87312
Latitude:
42.369025
Time Zone:
America/Los_Angeles
SFO Address & GPS
Address:
San Francisco CA, 94128
United States
IATA Code:
SFO
Longitude:
-122.389881
Latitude:
37.615215
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from MFR to San Francisco Intl. Airport (SFO)?
Forget about lengthy stopovers or missing that connecting flight. United Airlines will get you directly from Rogue Valley Intl. Airport (MFR) to San Francisco Airport.
What is the shortest flight from Rogue Valley Intl. Airport (MFR) to San Francisco Airport?
From Medford, the wonderful sights and sounds of San Francisco are 3 hours and 59 minutes away. Secure your favorite seat, or perhaps even one with a bit more legroom, and fly to your destination in pure comfort.
How many hours flight from Rogue Valley Intl. Airport (MFR) to San Francisco Airport?
With a general flight time of about 4 hours and 6 minutes between MFR and SFO, you'll be enjoying San Francisco before you can utter, "How much longer to go?"
What airlines have the most flights from MFR to San Francisco Airport?
If you're after a drama-free trip, lock in your ticket with United Airlines. This carrier offers 60 flights every month from MFR to SFO and is one of the best airlines operating on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore