Cheap flights from MFR to SAN (Rogue Valley Intl. to San Diego Intl.)

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Cheap Flights from MFR to SAN starting at $129 One Way, $203 Round Trip

Prices starting at $203 for return flights and $129 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Dec 5 - Fri, Dec 11
MFR
Medford
SAN
San Diego
$203 Roundtrip, found 2 days ago
$203
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Sat, Dec 5 from Medford to San Diego, returning Fri, Dec 11, priced at $203 found 2 days ago
Tue, Oct 27 - Sat, Oct 31
MFR
Medford
SAN
San Diego
$206 Roundtrip, found 4 days ago
$206
Roundtrip
found 4 days ago
Select Alaska Airlines flight, departing Tue, Oct 27 from Medford to San Diego, returning Sat, Oct 31, priced at $206 found 4 days ago
Sat, Dec 5 - Fri, Dec 11
MFR
Medford
SAN
San Diego
$220 Roundtrip, found 2 days ago
$220
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Sat, Dec 5 from Medford to San Diego, returning Fri, Dec 11, priced at $220 found 2 days ago
Tue, Oct 27 - Sat, Oct 31
MFR
Medford
SAN
San Diego
$223 Roundtrip, found 4 days ago
$223
Roundtrip
found 4 days ago
Select Alaska Airlines flight, departing Tue, Oct 27 from Medford to San Diego, returning Sat, Oct 31, priced at $223 found 4 days ago
Sat, Dec 5 - Fri, Dec 11
MFR
Medford
SAN
San Diego
$230 Roundtrip, found 2 days ago
$230
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Sat, Dec 5 from Medford to San Diego, returning Fri, Dec 11, priced at $230 found 2 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$213 nightly
The price is $245 total per night from Sep 27 to Sep 28
$245 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Sep 20 to Sep 21
$211 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,310 reviews)
"Here for a vacation and this spot was fantastic. Such a great central location. Perfect for walking to Little Italy or even the Gas Lamp. Even a decent walk to the zoo. Beautiful views of the harbor and easy access to the Coronado shuttle"

Reviewed on Sep 11, 2026

Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$118 nightly
The price is $136 total per night from Oct 7 to Oct 8
$136 total
Oct 7 - Oct 8
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$118 nightly
The price is $136 total per night from Oct 7 to Oct 8
$136 total
Oct 7 - Oct 8
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
Handlery Hotel
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
$85 nightly
The price is $97 total per night from Sep 13 to Sep 14
$97 total
Sep 13 - Sep 14
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
Best Western Seven Seas
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Sep 20 to Sep 21
$211 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,310 reviews)
"Here for a vacation and this spot was fantastic. Such a great central location. Perfect for walking to Little Italy or even the Gas Lamp. Even a decent walk to the zoo. Beautiful views of the harbor and easy access to the Coronado shuttle"

Reviewed on Sep 11, 2026

Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Sep 20 to Sep 21
$211 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,310 reviews)
"Here for a vacation and this spot was fantastic. Such a great central location. Perfect for walking to Little Italy or even the Gas Lamp. Even a decent walk to the zoo. Beautiful views of the harbor and easy access to the Coronado shuttle"

Reviewed on Sep 11, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$213 nightly
The price is $245 total per night from Sep 27 to Sep 28
$245 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$144 nightly
The price is $166 total per night from Sep 23 to Sep 24
$166 total
Sep 23 - Sep 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,085 reviews)
"The room was immaculate and the shuttle was a huge help for traveling to and from mcrd"

Reviewed on Sep 11, 2026

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$94 nightly
The price is $107 total per night from Sep 13 to Sep 14
$107 total
Sep 13 - Sep 14
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$71 nightly
The price is $81 total per night from Sep 13 to Sep 14
$81 total
Sep 13 - Sep 14
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$92 nightly
The price is $105 total per night from Oct 13 to Oct 14
$105 total
Oct 13 - Oct 14
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,746 reviews)
"I have been coming to the Kings in for over 15 years. When my kids were younger, we’d come and stay because the access to the pool is so convenient. We also love the breakfast and dinner on site. I’m now travel often for work and not only is this place fairly priced but it’s so clean and everyone ..."

Reviewed on Sep 11, 2026

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$223 nightly
The price is $257 total per night from Oct 12 to Oct 13
$257 total
Oct 12 - Oct 13
Total with taxes and fees
Book a stay at this business-friendly resort in San Diego. Enjoy breakfast (surcharge), 24-hour room service, and a fitness center. Our guests praise the pool ...
Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$186 nightly
The price is $213 total per night from Sep 28 to Sep 29
$213 total
Sep 28 - Sep 29
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,419 reviews)
"My family and i stayed for a one night stay and it was very nice. Very family friendly. We most enjoyed the night swim in the heated pool while enjoying the movie night! The room was clean, the shuttle ride to and from Seaworld was top tier!"

Reviewed on Sep 11, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$245 nightly
The price is $282 total per night from Oct 12 to Oct 13
$282 total
Oct 12 - Oct 13
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,360 reviews)

Families like: Outdoor pool, game room, on the beach, bicycle rentals

Travelers say...
"We really enjoyed our long weekend stay. The resort is great for kids! Having the pool and the bay on the property, and the actual beach just a short walk away was all very convenient. There were showers at the pool and the bay for convenient rinsing, and the free arcade games were fun for the family. ..."

Reviewed on Sep 10, 2026

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MFR to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MFR Address & GPS
Address:
1000 Terminal Spur Rd.
Medford OR, 97504
United States
IATA Code:
MFR
Longitude:
-122.87312
Latitude:
42.369025
Time Zone:
America/Los_Angeles
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Medford Airport to San Diego Intl. Airport (SAN)?
With no direct flights currently servicing the route from MFR to San Diego Intl. Airport (SAN), your best bet is to pick an airline that offers just one easy stopover. Rack up those air miles with Alaska Airlines, United Airlines or Delta Air Lines.
What is the shortest flight from MFR to SAN?
Getting from MFR to SAN takes at least 3 hours and 56 minutes. Savor a wine and get stuck into that book — it's the ideal opportunity to simply relax.
How many hours flight from Rogue Valley Intl. Airport (MFR) to San Diego Airport?
It usually takes around 4 hours and 4 minutes to jet from Rogue Valley Intl. Airport (MFR) to San Diego Intl. Airport (SAN). You'll be in the sky for a while, so take your own entertainment, like a newspaper or some movies.
What airlines have the most flights from MFR to San Diego Intl. Airport (SAN)?
If you're wanting to book with an airline that flies direct from Rogue Valley Intl. Airport (MFR) to SAN, it's not going to happen. You'll have to book a flight with at least one stopover to get to San Diego.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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