Cheap flights from MFR to SAN (Rogue Valley Intl. to San Diego Intl.)

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Cheap Flights from MFR to SAN starting at $129 One Way, $197 Round Trip

Prices starting at $197 for return flights and $129 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Sep 30 - Sat, Oct 3
MFR
Medford
SAN
San Diego
$197 Roundtrip, found 6 days ago
$197
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Wed, Sep 30 from Medford to San Diego, returning Sat, Oct 3, priced at $197 found 6 days ago
Sat, Sep 12 - Sat, Sep 19
MFR
Medford
SAN
San Diego
$200 Roundtrip, found 6 days ago
$200
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Sat, Sep 12 from Medford to San Diego, returning Sat, Sep 19, priced at $200 found 6 days ago
Sat, Aug 29 - Sat, Sep 5
MFR
Medford
SAN
San Diego
$211 Roundtrip, found 5 days ago
$211
Roundtrip
found 5 days ago
Select Alaska Airlines flight, departing Sat, Aug 29 from Medford to San Diego, returning Sat, Sep 5, priced at $211 found 5 days ago
Sat, Sep 5 - Sat, Sep 12
MFR
Medford
SAN
San Diego
$213 Roundtrip, found 6 days ago
$213
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Sat, Sep 5 from Medford to San Diego, returning Sat, Sep 12, priced at $213 found 6 days ago
Wed, Oct 28 - Tue, Nov 3
MFR
Medford
SAN
San Diego
$215 Roundtrip, found 2 days ago
$215
Roundtrip
found 2 days ago
Select Bargain Flight flight, departing Wed, Oct 28 from Medford to San Diego, returning Tue, Nov 3, priced at $215 found 2 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$169 nightly
The price is $194 total per night from Aug 23 to Aug 24
$194 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,641 reviews)
"Very clean, nice place with everything you need"

Reviewed on Aug 4, 2026

Sheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Aug 12 to Aug 13
$211 total
Aug 12 - Aug 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,251 reviews)
"Front desk aurora very helpful friendly and professional. Thank you check in was great because of her"

Reviewed on Aug 5, 2026

Wyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$250 nightly
The price is $290 total per night from Aug 26 to Aug 27
$290 total
Aug 26 - Aug 27
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the ...
9/10 Wonderful! (2,765 reviews)
"The hotel was at capacity yet, Basil at the front desk helped my family and I immensely with a smile and extremely helpful information regarding the property. He really went above and beyond for us."

Reviewed on Aug 5, 2026

Manchester Grand Hyatt San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
$285 nightly
The price is $328 total per night from Aug 30 to Aug 31
$328 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,796 reviews)
"We enjoyed the secluded-ish feel of the location and the resort's layout is nice and walkable. The tropical feel of the resort with tropical plants and trees is nice. There are multiple pools and they were nice. Resort gives a family-friendly vibe. The rooms themselves were clean but have a dated ..."

Reviewed on Aug 5, 2026

Paradise Point Resort & Spa
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$250 nightly
The price is $290 total per night from Aug 26 to Aug 27
$290 total
Aug 26 - Aug 27
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the ...
9/10 Wonderful! (2,765 reviews)
"The hotel was at capacity yet, Basil at the front desk helped my family and I immensely with a smile and extremely helpful information regarding the property. He really went above and beyond for us."

Reviewed on Aug 5, 2026

Manchester Grand Hyatt San Diego
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Aug 12 to Aug 13
$211 total
Aug 12 - Aug 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,251 reviews)
"Front desk aurora very helpful friendly and professional. Thank you check in was great because of her"

Reviewed on Aug 5, 2026

Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Aug 12 to Aug 13
$211 total
Aug 12 - Aug 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,251 reviews)
"Front desk aurora very helpful friendly and professional. Thank you check in was great because of her"

Reviewed on Aug 5, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$169 nightly
The price is $194 total per night from Aug 23 to Aug 24
$194 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,641 reviews)
"Very clean, nice place with everything you need"

Reviewed on Aug 4, 2026

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$153 nightly
The price is $176 total per night from Sep 1 to Sep 2
$176 total
Sep 1 - Sep 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,087 reviews)
"This is a perfect place for me to stay as I had a very early morning flight the next day thank you to the staff for accommodating me."

Reviewed on Aug 4, 2026

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$110 nightly
The price is $126 total per night from Aug 9 to Aug 10
$126 total
Aug 9 - Aug 10
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$83 nightly
The price is $96 total per night from Aug 6 to Aug 7
$96 total
Aug 6 - Aug 7
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.6/10 (2,156 reviews)
"Nice simple stay. Close to restaurante, and even closer to the old town train station. Nice simple hotel."

Reviewed on Aug 4, 2026

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$130 nightly
The price is $149 total per night from Aug 31 to Sep 1
$149 total
Aug 31 - Sep 1
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,760 reviews)
"Great"

Reviewed on Aug 5, 2026

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$287 nightly
The price is $330 total per night from Aug 30 to Aug 31
$330 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,320 reviews)
"A little dated, and could use some updates but what a magnificent location and wonderful staff."

Reviewed on Aug 5, 2026

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$234 nightly
The price is $269 total per night from Sep 1 to Sep 2
$269 total
Sep 1 - Sep 2
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$335 nightly
The price is $385 total per night from Sep 1 to Sep 2
$385 total
Sep 1 - Sep 2
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MFR to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MFR Address & GPS
Address:
1000 Terminal Spur Rd.
Medford OR, 97504
United States
IATA Code:
MFR
Longitude:
-122.87312
Latitude:
42.369025
Time Zone:
America/Los_Angeles
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Medford Airport to San Diego Intl. Airport (SAN)?
With no direct flights currently servicing the route from MFR to San Diego Intl. Airport (SAN), your best bet is to pick an airline that offers just one easy stopover. Rack up those air miles with Alaska Airlines, United Airlines or Delta Air Lines.
What is the shortest flight from MFR to SAN?
Getting from MFR to SAN takes at least 3 hours and 56 minutes. Savor a wine and get stuck into that book — it's the ideal opportunity to simply relax.
How many hours flight from Rogue Valley Intl. Airport (MFR) to San Diego Airport?
It usually takes around 4 hours and 4 minutes to jet from Rogue Valley Intl. Airport (MFR) to San Diego Intl. Airport (SAN). You'll be in the sky for a while, so take your own entertainment, like a newspaper or some movies.
What airlines have the most flights from MFR to San Diego Intl. Airport (SAN)?
If you're wanting to book with an airline that flies direct from Rogue Valley Intl. Airport (MFR) to SAN, it's not going to happen. You'll have to book a flight with at least one stopover to get to San Diego.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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