Cheap flights from MFR to SAN (Rogue Valley Intl. to San Diego Intl.)

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Cheap Flights from MFR to SAN starting at $94 One Way, $222 Round Trip

Prices starting at $222 for return flights and $94 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Dec 16 - Thu, Dec 17
MFR
Medford
SAN
San Diego
$222 Roundtrip, found 1 day ago
$222
Roundtrip
found 1 day ago
Select United flight, departing Wed, Dec 16 from Medford to San Diego, returning Thu, Dec 17, priced at $222 found 1 day ago
Wed, Dec 16 - Thu, Dec 17
MFR
Medford
SAN
San Diego
$228 Roundtrip, found 1 day ago
$228
Roundtrip
found 1 day ago
Select United flight, departing Wed, Dec 16 from Medford to San Diego, returning Thu, Dec 17, priced at $228 found 1 day ago
Tue, Jan 5 - Wed, Feb 3
MFR
Medford
SAN
San Diego
$247 Roundtrip, found 11 hours ago
$247
Roundtrip
found 11 hours ago
Select Alaska Airlines flight, departing Tue, Jan 5 from Medford to San Diego, returning Wed, Feb 3, priced at $247 found 11 hours ago
Tue, Jan 5 - Wed, Feb 3
MFR
Medford
SAN
San Diego
$257 Roundtrip, found 11 hours ago
$257
Roundtrip
found 11 hours ago
Select Alaska Airlines flight, departing Tue, Jan 5 from Medford to San Diego, returning Wed, Feb 3, priced at $257 found 11 hours ago
Sat, Feb 13 - Wed, Feb 17
MFR
Medford
SAN
San Diego
$264 Roundtrip, found 21 hours ago
$264
Roundtrip
found 21 hours ago
Select Bargain Flight flight, departing Sat, Feb 13 from Medford to San Diego, returning Wed, Feb 17, priced at $264 found 21 hours ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$160 nightly
The price is $184 total per night from Nov 22 to Nov 23
$184 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$170 nightly
The price is $197 total per night from Nov 22 to Nov 23
$197 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,363 reviews)
"Got charges not expecting"

Reviewed on Nov 6, 2026

Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$90 nightly
The price is $104 total per night from Dec 1 to Dec 2
$104 total
Dec 1 - Dec 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$170 nightly
The price is $197 total per night from Nov 22 to Nov 23
$197 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,363 reviews)
"Got charges not expecting"

Reviewed on Nov 6, 2026

Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$90 nightly
The price is $104 total per night from Dec 1 to Dec 2
$104 total
Dec 1 - Dec 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
Handlery Hotel
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
$189 nightly
The price is $219 total per night from Dec 6 to Dec 7
$219 total
Dec 6 - Dec 7
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (4,581 reviews)
"Convenient location, expensive valet for car (my opinion)."

Reviewed on Nov 5, 2026

Hard Rock Hotel San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$170 nightly
The price is $197 total per night from Nov 22 to Nov 23
$197 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,363 reviews)
"Got charges not expecting"

Reviewed on Nov 6, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$160 nightly
The price is $184 total per night from Nov 22 to Nov 23
$184 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$136 nightly
The price is $156 total per night from Nov 9 to Nov 10
$156 total
Nov 9 - Nov 10
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$83 nightly
The price is $95 total per night from Dec 7 to Dec 8
$95 total
Dec 7 - Dec 8
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.6/10 Excellent! (1,631 reviews)
"Convenient location. Clean rooms. Not much more to ask for."

Reviewed on Nov 6, 2026

Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$73 nightly
The price is $84 total per night from Nov 8 to Nov 9
$84 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$97 nightly
The price is $111 total per night from Nov 9 to Nov 10
$111 total
Nov 9 - Nov 10
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,837 reviews)
"The room was very clean. The staff were very helpful when checking in and out."

Reviewed on Nov 6, 2026

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$175 nightly
The price is $202 total per night from Dec 6 to Dec 7
$202 total
Dec 6 - Dec 7
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free parking, a private beach, and a marina. Our guests praise the pool and the restaurant in our reviews. ...
Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$194 nightly
The price is $223 total per night from Nov 30 to Dec 1
$223 total
Nov 30 - Dec 1
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,489 reviews)
"i like the property, i stayed on ground floor which was fine. the bars on slider are odd. have there been issues? desk person told me there are alot of homeless near the park, so that worried me too."

Reviewed on Nov 6, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$229 nightly
The price is $264 total per night from Dec 6 to Dec 7
$264 total
Dec 6 - Dec 7
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MFR to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MFR Address & GPS
Address:
1000 Terminal Spur Rd.
Medford OR, 97504
United States
IATA Code:
MFR
Longitude:
-122.87312
Latitude:
42.369025
Time Zone:
America/Los_Angeles
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Medford Airport to San Diego Intl. Airport (SAN)?
With no direct flights currently servicing the route from MFR to San Diego Intl. Airport (SAN), your best bet is to pick an airline that offers just one easy stopover. Rack up those air miles with Alaska Airlines, United Airlines or Delta Air Lines.
What is the shortest flight from MFR to SAN?
Getting from MFR to SAN takes at least 3 hours and 56 minutes. Savor a wine and get stuck into that book — it's the ideal opportunity to simply relax.
How many hours flight from Rogue Valley Intl. Airport (MFR) to San Diego Airport?
It usually takes around 4 hours and 4 minutes to jet from Rogue Valley Intl. Airport (MFR) to San Diego Intl. Airport (SAN). You'll be in the sky for a while, so take your own entertainment, like a newspaper or some movies.
What airlines have the most flights from MFR to San Diego Intl. Airport (SAN)?
If you're wanting to book with an airline that flies direct from Rogue Valley Intl. Airport (MFR) to SAN, it's not going to happen. You'll have to book a flight with at least one stopover to get to San Diego.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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