Cheap flights from MFR to SAN (Rogue Valley Intl. to San Diego Intl.)

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Cheap Flights from MFR to SAN starting at $129 One Way, $215 Round Trip

Prices starting at $215 for return flights and $129 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Oct 28 - Tue, Nov 3
MFR
Medford
SAN
San Diego
$215 Roundtrip, found 4 days ago
$215
Roundtrip
found 4 days ago
Select Bargain Flight flight, departing Wed, Oct 28 from Medford to San Diego, returning Tue, Nov 3, priced at $215 found 4 days ago
Sat, Sep 19 - Tue, Sep 22
MFR
Medford
SAN
San Diego
$220 Roundtrip, found 3 days ago
$220
Roundtrip
found 3 days ago
Select Alaska Airlines flight, departing Sat, Sep 19 from Medford to San Diego, returning Tue, Sep 22, priced at $220 found 3 days ago
Wed, Oct 28 - Tue, Nov 3
MFR
Medford
SAN
San Diego
$232 Roundtrip, found 4 days ago
$232
Roundtrip
found 4 days ago
Select United flight, departing Wed, Oct 28 from Medford to San Diego, returning Tue, Nov 3, priced at $232 found 4 days ago
Sat, Oct 24 - Sat, Oct 31
MFR
Medford
SAN
San Diego
$237 Roundtrip, found 14 hours ago
$237
Roundtrip
found 14 hours ago
Select Alaska Airlines flight, departing Sat, Oct 24 from Medford to San Diego, returning Sat, Oct 31, priced at $237 found 14 hours ago
Wed, Sep 9 - Tue, Sep 15
MFR
Medford
SAN
San Diego
$240 Roundtrip, found 4 days ago
$240
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Sep 9 from Medford to San Diego, returning Tue, Sep 15, priced at $240 found 4 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$169 nightly
The price is $194 total per night from Aug 23 to Aug 24
$194 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Aug 12 to Aug 13
$211 total
Aug 12 - Aug 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,261 reviews)
"old looking buildings. staff nowhere near sufficient number."

Reviewed on Aug 6, 2026

Wyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$216 nightly
The price is $250 total per night from Sep 7 to Sep 8
$250 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the ...
9/10 Wonderful! (2,770 reviews)
"I enjoyed my stay and would happily return if I’m in the area."

Reviewed on Aug 6, 2026

Manchester Grand Hyatt San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
$269 nightly
The price is $309 total per night from Sep 7 to Sep 8
$309 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Paradise Point Resort & Spa
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$216 nightly
The price is $250 total per night from Sep 7 to Sep 8
$250 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the ...
9/10 Wonderful! (2,770 reviews)
"I enjoyed my stay and would happily return if I’m in the area."

Reviewed on Aug 6, 2026

Manchester Grand Hyatt San Diego
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Aug 12 to Aug 13
$211 total
Aug 12 - Aug 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,261 reviews)
"old looking buildings. staff nowhere near sufficient number."

Reviewed on Aug 6, 2026

Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Aug 12 to Aug 13
$211 total
Aug 12 - Aug 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,261 reviews)
"old looking buildings. staff nowhere near sufficient number."

Reviewed on Aug 6, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$169 nightly
The price is $194 total per night from Aug 23 to Aug 24
$194 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$153 nightly
The price is $176 total per night from Sep 1 to Sep 2
$176 total
Sep 1 - Sep 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$110 nightly
The price is $126 total per night from Aug 10 to Aug 11
$126 total
Aug 10 - Aug 11
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.6/10 Excellent! (1,527 reviews)
"The staff were kind, the parking is ample and there's walkable food locations nearby."

Reviewed on Aug 7, 2026

Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$93 nightly
The price is $106 total per night from Aug 9 to Aug 10
$106 total
Aug 9 - Aug 10
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$120 nightly
The price is $137 total per night from Aug 10 to Aug 11
$137 total
Aug 10 - Aug 11
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$239 nightly
The price is $275 total per night from Sep 7 to Sep 8
$275 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.6/10 Excellent! (2,328 reviews)
"It was mine and my partners anniversary vacation so we decided to check out this resort. We get there the first day at 6:00pm, the check-in was supposed to be at 4:00pm and they proceeded to tell us that our room was not ready because it needed to be inspected. I left my phone number and they call ..."

Reviewed on Aug 7, 2026

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$214 nightly
The price is $246 total per night from Sep 7 to Sep 8
$246 total
Sep 7 - Sep 8
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,439 reviews)
"the rooms are very assesible don't have to walk a long way around"

Reviewed on Aug 6, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$261 nightly
The price is $301 total per night from Sep 7 to Sep 8
$301 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MFR to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MFR Address & GPS
Address:
1000 Terminal Spur Rd.
Medford OR, 97504
United States
IATA Code:
MFR
Longitude:
-122.87312
Latitude:
42.369025
Time Zone:
America/Los_Angeles
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Medford Airport to San Diego Intl. Airport (SAN)?
With no direct flights currently servicing the route from MFR to San Diego Intl. Airport (SAN), your best bet is to pick an airline that offers just one easy stopover. Rack up those air miles with Alaska Airlines, United Airlines or Delta Air Lines.
What is the shortest flight from MFR to SAN?
Getting from MFR to SAN takes at least 3 hours and 56 minutes. Savor a wine and get stuck into that book — it's the ideal opportunity to simply relax.
How many hours flight from Rogue Valley Intl. Airport (MFR) to San Diego Airport?
It usually takes around 4 hours and 4 minutes to jet from Rogue Valley Intl. Airport (MFR) to San Diego Intl. Airport (SAN). You'll be in the sky for a while, so take your own entertainment, like a newspaper or some movies.
What airlines have the most flights from MFR to San Diego Intl. Airport (SAN)?
If you're wanting to book with an airline that flies direct from Rogue Valley Intl. Airport (MFR) to SAN, it's not going to happen. You'll have to book a flight with at least one stopover to get to San Diego.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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