Cheap flights from MFR to SFO (Rogue Valley Intl. to San Francisco Intl.)

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Cheap Flights from MFR to SFO starting at $143 One Way, $292 Round Trip

Prices starting at $292 for return flights and $143 for one-way flights to San Francisco Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Dec 2 - Mon, Dec 7
MFR
Medford
SFO
San Francisco
$292 Roundtrip, found 5 days ago
$292
Roundtrip
found 5 days ago
Select Alaska Airlines flight, departing Wed, Dec 2 from Medford to San Francisco, returning Mon, Dec 7, priced at $292 found 5 days ago
Thu, Jun 10 - Fri, Jun 11
MFR
Medford
SFO
San Francisco
$295 Roundtrip, found 5 days ago
$295
Roundtrip
found 5 days ago
Select Bargain Flight flight, departing Thu, Jun 10 from Medford to San Francisco, returning Fri, Jun 11, priced at $295 found 5 days ago
Sun, Mar 14 - Thu, Apr 15
MFR
Medford
SFO
San Francisco
$299 Roundtrip, found 2 days ago
$299
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Sun, Mar 14 from Medford to San Francisco, returning Thu, Apr 15, priced at $299 found 2 days ago
Tue, Dec 8 - Wed, Jan 20
MFR
Medford
SFO
San Francisco
$304 Roundtrip, found 2 days ago
$304
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Tue, Dec 8 from Medford to San Francisco, returning Wed, Jan 20, priced at $304 found 2 days ago
Mon, Nov 16 - Tue, Nov 17
MFR
Medford
SFO
San Francisco
$308 Roundtrip, found 4 days ago
$308
Roundtrip
found 4 days ago
Select Bargain Flight flight, departing Mon, Nov 16 from Medford to San Francisco, returning Tue, Nov 17, priced at $308 found 4 days ago

Hotel Ideas near San Francisco Intl.

Airport Hotels near San Francisco Intl.

Grand Hyatt at SFO

Grand Hyatt at SFO

4 out of 5
55 S McDonnell Rd San Francisco CA
$289 nightly
The price is $323 total per night from Nov 23 to Nov 24
$323 total
Nov 23 - Nov 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the restaurant ...
Grand Hyatt at SFO
The Millwood - A Boutique Hotel

The Millwood - A Boutique Hotel

3 out of 5
1375 El Camino Real Millbrae CA
$134 nightly
The price is $153 total per night from Nov 22 to Nov 23
$153 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Millbrae. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
The Millwood - A Boutique Hotel
The Westin San Francisco Airport

The Westin San Francisco Airport

4 out of 5
1 Old Bayshore Hwy Millbrae CA
$127 nightly
The price is $146 total per night from Nov 22 to Nov 23
$146 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Millbrae. Enjoy breakfast (surcharge), a free airport shuttle, and a 24-hour fitness center. Our guests praise ...
8.8/10 Excellent! (1,782 reviews)
"Great location near airport."

Reviewed on Nov 6, 2026

The Westin San Francisco Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Francisco

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
$119 nightly
The price is $140 total per night from Nov 29 to Nov 30
$140 total
Nov 29 - Nov 30
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9/10 Wonderful! (6,467 reviews)
"Good location in San Francisco. Public transportation was easily available. Great to have a parking garage onsite. We paid in advance."

Reviewed on Nov 6, 2026

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
$154 nightly
The price is $181 total per night from Nov 8 to Nov 9
$181 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,738 reviews)
"The room was clean, the staff was friendly and beyond attentive, and the breakfast was delicious. Very happy with my stay!"

Reviewed on Nov 7, 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
$151 nightly
The price is $178 total per night from Nov 22 to Nov 23
$178 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
Hilton San Francisco Union Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Francisco Hotels With Airport Transportation

The Dylan at SFO

The Dylan at SFO

3 out of 5
110 S El Camino Real Millbrae CA
$126 nightly
The price is $149 total per night from Nov 30 to Dec 1
$149 total
Nov 30 - Dec 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Millbrae. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
The Dylan at SFO
Hotel Skye SFO

Hotel Skye SFO

3 out of 5
421 El Camino Real San Bruno CA
$124 nightly
The price is $142 total per night from Nov 22 to Nov 23
$142 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in San Bruno. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (2,103 reviews)
"We enjoyed our stay"

Reviewed on Nov 7, 2026

Hotel Skye SFO
Sfo El Rancho Inn

Sfo El Rancho Inn

3 out of 5
1100 El Camino Real Millbrae CA
Book a stay at this business-friendly hotel in Millbrae. Enjoy free breakfast, an outdoor pool, and a 24-hour fitness center. Our guests praise the breakfast ...
8.4/10 Very Good! (2,678 reviews)
"Customer service was great"

Reviewed on Aug 1, 2026

Get rates
Sfo El Rancho Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Francisco Hotels

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

2 out of 5
326 S Airport Blvd South San Francisco CA
$68 nightly
The price is $80 total per night from Dec 4 to Dec 5
$80 total
Dec 4 - Dec 5
Total with taxes and fees
Book a stay at this business-friendly motel in South San Francisco. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the clean ...
Travelodge by Wyndham San Francisco Airport North
Hotel North Beach

Hotel North Beach

2 out of 5
935 Kearny Street San Francisco CA
$85 nightly
The price is $100 total per night from Nov 8 to Nov 9
$100 total
Nov 8 - Nov 9
Total with taxes and fees
Stay at this hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and laundry facilities. Our guests praise the helpful staff and the clean rooms in ...
Hotel North Beach
Hotel Skye SFO

Hotel Skye SFO

3 out of 5
421 El Camino Real San Bruno CA
$124 nightly
The price is $142 total per night from Nov 22 to Nov 23
$142 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in San Bruno. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (2,103 reviews)
"We enjoyed our stay"

Reviewed on Nov 7, 2026

Hotel Skye SFO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Francisco

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

4 out of 5
250 Beach Street San Francisco CA
$160 nightly
The price is $189 total per night from Nov 24 to Nov 25
$189 total
Nov 24 - Nov 25
Total with taxes and fees
Book a stay at this boutique hotel in San Francisco. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff ...
Hotel Zephyr San Francisco
Embassy Suites by Hilton San Francisco Airport Waterfront

Embassy Suites by Hilton San Francisco Airport Waterfront

3.5 out of 5
150 Anza Blvd Burlingame CA
$155 nightly
The price is $176 total per night from Nov 13 to Nov 14
$176 total
Nov 13 - Nov 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Burlingame. Enjoy free breakfast, WiFi (surcharge), and parking (surcharge). Our guests praise the breakfast and ...
Embassy Suites by Hilton San Francisco Airport Waterfront
Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point

3.5 out of 5
250 Gateway Blvd South San Francisco CA
$147 nightly
The price is $172 total per night from Dec 5 to Dec 6
$172 total
Dec 5 - Dec 6
Total with taxes and fees
Book a stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, a free airport shuttle, and a 24-hour fitness center. Our guests praise ...
Embassy Suites by Hilton San Francisco Airport Oyster Point
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MFR to SFO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MFR Address & GPS
Address:
1000 Terminal Spur Rd.
Medford OR, 97504
United States
IATA Code:
MFR
Longitude:
-122.87312
Latitude:
42.369025
Time Zone:
America/Los_Angeles
SFO Address & GPS
Address:
San Francisco CA, 94128
United States
IATA Code:
SFO
Longitude:
-122.389881
Latitude:
37.615215
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from MFR to San Francisco Intl. Airport (SFO)?
Forget about lengthy stopovers or missing that connecting flight. United Airlines will get you directly from Rogue Valley Intl. Airport (MFR) to San Francisco Airport.
What is the shortest flight from Rogue Valley Intl. Airport (MFR) to San Francisco Airport?
From Medford, the wonderful sights and sounds of San Francisco are 3 hours and 59 minutes away. Secure your favorite seat, or perhaps even one with a bit more legroom, and fly to your destination in pure comfort.
How many hours flight from Rogue Valley Intl. Airport (MFR) to San Francisco Airport?
With a general flight time of about 4 hours and 6 minutes between MFR and SFO, you'll be enjoying San Francisco before you can utter, "How much longer to go?"
What airlines have the most flights from MFR to San Francisco Airport?
If you're after a drama-free trip, lock in your ticket with United Airlines. This carrier offers 60 flights every month from MFR to SFO and is one of the best airlines operating on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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