Cheap flights from MDT to SAT (Harrisburg Intl. to San Antonio Intl.)

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Cheap Flights from MDT to SAT starting at $172 One Way, $393 Round Trip

Prices starting at $393 for return flights and $172 for one-way flights to San Antonio Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Apr 12 - Wed, Apr 15
MDT
Harrisburg
SAT
San Antonio
$393 Roundtrip, found 1 day ago
$393
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Apr 12 from Harrisburg to San Antonio, returning Wed, Apr 15, priced at $393 found 1 day ago
Sun, Apr 12 - Wed, Apr 15
MDT
Harrisburg
SAT
San Antonio
$403 Roundtrip, found 1 day ago
$403
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Apr 12 from Harrisburg to San Antonio, returning Wed, Apr 15, priced at $403 found 1 day ago
Sun, Apr 12 - Wed, Apr 15
MDT
Harrisburg
SAT
San Antonio
$414 Roundtrip, found 1 day ago
$414
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Apr 12 from Harrisburg to San Antonio, returning Wed, Apr 15, priced at $414 found 1 day ago
Sun, Apr 12 - Wed, Apr 15
MDT
Harrisburg
SAT
San Antonio
$414 Roundtrip, found 1 day ago
$414
Roundtrip
found 1 day ago
Select United flight, departing Sun, Apr 12 from Harrisburg to San Antonio, returning Wed, Apr 15, priced at $414 found 1 day ago
Sun, Apr 12 - Wed, Apr 15
MDT
Harrisburg
SAT
San Antonio
$415 Roundtrip, found 1 day ago
$415
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Apr 12 from Harrisburg to San Antonio, returning Wed, Apr 15, priced at $415 found 1 day ago

Hotel Ideas near San Antonio Intl.

Airport Hotels near San Antonio Intl.

Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport

3 out of 5
8818 Jones Maltsberger Rd San Antonio TX
$89 nightly
The price is $105 total per night from Apr 5 to Apr 6
$105 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,318 reviews)
Elevator was out most of our stay. Top floor smelled like weed the entire stay. The room was nice and the staff was very accommodating.

Reviewed on Mar 31, 2026

Wyndham Garden San Antonio Airport
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

2.5 out of 5
143 NE Loop 410 San Antonio TX
$80 nightly
The price is $95 total per night from Apr 5 to Apr 6
$95 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,650 reviews)
I didn't take breakfast

Reviewed on Mar 31, 2026

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
La Quinta Inn & Suites by Wyndham San Antonio Airport

La Quinta Inn & Suites by Wyndham San Antonio Airport

3 out of 5
850 Halm Blvd San Antonio TX
$71 nightly
The price is $84 total per night from Apr 19 to Apr 20
$84 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (2,755 reviews)
Good

Reviewed on Mar 31, 2026

La Quinta Inn & Suites by Wyndham San Antonio Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Antonio

Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
$99 nightly
The price is $117 total per night from Apr 5 to Apr 6
$117 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (6,425 reviews)
The images from the website doesn’t not match what the place looks like at all rooms did not match what they were selling. Felt old and outdated.

Reviewed on Mar 31, 2026

Riverwalk Plaza
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
$150 nightly
The price is $177 total per night from Apr 26 to Apr 27
$177 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (2,599 reviews)
Great place. Perfect location

Reviewed on Mar 31, 2026

Hotel Valencia Riverwalk
Menger Hotel

Menger Hotel

3.5 out of 5
204 Alamo Plaza San Antonio TX
$109 nightly
The price is $129 total per night from Apr 7 to Apr 8
$129 total
Apr 7 - Apr 8
Total with taxes and fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (3,877 reviews)
No ghosts and not allowed to play the 4 pianos in the lobby…

Reviewed on Mar 30, 2026

Menger Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Antonio Hotels With Airport Transportation

Hampton Inn & Suites San Antonio-Airport

Hampton Inn & Suites San Antonio-Airport

2.5 out of 5
8902 Jones Maltsberger Rd San Antonio TX
$91 nightly
The price is $107 total per night from Apr 18 to Apr 19
$107 total
Apr 18 - Apr 19
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (1,951 reviews)
The atar

Reviewed on Mar 31, 2026

Hampton Inn & Suites San Antonio-Airport
Hilton Garden Inn San Antonio Airport South

Hilton Garden Inn San Antonio Airport South

3 out of 5
8505 Broadway Street San Antonio TX
$86 nightly
The price is $101 total per night from Apr 12 to Apr 13
$101 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,004 reviews)
Breakfast was good. Staff is very friendly and accommodating. Love it there

Reviewed on Mar 29, 2026

Hilton Garden Inn San Antonio Airport South
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

2.5 out of 5
143 NE Loop 410 San Antonio TX
$80 nightly
The price is $95 total per night from Apr 5 to Apr 6
$95 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,650 reviews)
I didn't take breakfast

Reviewed on Mar 31, 2026

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Antonio Hotels

Days Inn by Wyndham San Antonio Alamo/Riverwalk

Days Inn by Wyndham San Antonio Alamo/Riverwalk

2 out of 5
400 Bowie Street San Antonio TX
$61 nightly
The price is $71 total per night from Apr 6 to Apr 7
$71 total
Apr 6 - Apr 7
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff and ...
7.2/10 Good! (1,426 reviews)
Just bad property to say. Don’t waste time.

Reviewed on Mar 31, 2026

Days Inn by Wyndham San Antonio Alamo/Riverwalk
Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk

Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk

2.5 out of 5
1011 E Houston St San Antonio TX
$67 nightly
The price is $80 total per night from Apr 5 to Apr 6
$80 total
Apr 5 - Apr 6
Total with taxes and fees
Stay at this hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
7/10 Good! (1,882 reviews)
it was fine in parking, the

Reviewed on Mar 30, 2026

Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk
Super 8 by Wyndham Universal City

Super 8 by Wyndham Universal City

2 out of 5
200 Palisades Dr Universal City TX
$43 nightly
The price is $50 total per night from Apr 26 to Apr 27
$50 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Universal City. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Regal Live Oak and Olympia ...
6.8/10 (1,012 reviews)
Go value. Clean and very basic.

Reviewed on Mar 30, 2026

Super 8 by Wyndham Universal City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Antonio

Hyatt Regency Hill Country Resort and Villas

Hyatt Regency Hill Country Resort and Villas

4 out of 5
9800 Hyatt Resort Dr San Antonio TX
$405 nightly
The price is $479 total per night from Apr 1 to Apr 2
$479 total
Apr 1 - Apr 2
Total with taxes and fees
Book a stay at this golf hotel in San Antonio. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,001 reviews)

Families like: Outdoor pools, free waterpark access, playground, game room

Travelers say...
Everything was amazing!

Reviewed on Mar 30, 2026

Hyatt Regency Hill Country Resort and Villas
Hotel Contessa

Hotel Contessa

4 out of 5
306 W Market Street San Antonio TX
$148 nightly
The price is $175 total per night from Apr 1 to Apr 2
$175 total
Apr 1 - Apr 2
Total with taxes and fees
Book a stay at this spa hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (3,501 reviews)
Mariachi band was excellent! Gorgeous hotel and friendly staff. Restaurant was amazing.

Reviewed on Mar 31, 2026

Hotel Contessa
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

3 out of 5
105 S Saint Marys Street San Antonio TX
$122 nightly
The price is $144 total per night from Apr 7 to Apr 8
$144 total
Apr 7 - Apr 8
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (4,428 reviews)
This hotel enjoys an ideal location. The Historic Market, Riverwalk, La Villita and the San Fernando Cathedral are all an easy walk. The hotel itself would benefit from a facelift. It feels tired and dated. Ancient carpeting, bathrooms that haven’t been updated in decades and a brown/beige color ...

Reviewed on Mar 30, 2026

Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MDT to SAT Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MDT Address & GPS
Address:
One Terminal Drive
Middletown PA, 17057
United States
IATA Code:
MDT
Longitude:
-76.756057
Latitude:
40.196008
Time Zone:
America/New_York
SAT Address & GPS
Address:
9800 Airport Boulevard
San Antonio TX, 78216
United States
IATA Code:
SAT
Longitude:
-98.472643
Latitude:
29.524937
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from MDT to San Antonio Airport?
Traveling from MDT to SAT means you'll need to change planes. But hey — there's no need to worry. American Airlines, Delta Air Lines and United Airlines offer flights with a single stopover.
What is the shortest flight from MDT to San Antonio Airport?
From Harrisburg, the wonderful sights and sounds of San Antonio are around 5 hours and 14 minutes away. Make sure you choose your favorite seat, or maybe even one with more legroom, and fly to your destination in total comfort.
How many hours flight from Harrisburg Intl. Airport to SAT?
Settle in and get comfy, because a typical plane trip from Harrisburg Intl. Airport to San Antonio Intl. Airport (SAT) is 5 hours and 19 minutes. Watch a few TV episodes, finish that book … You'll have plenty of time to sit back and enjoy the ride.
What airlines have the most flights from Harrisburg Intl. Airport (MDT) to San Antonio Intl. Airport (SAT)?
You'll need to make one or more stopovers if you're traveling from MDT to SAT. Right now, there are no airlines that advertise direct flights on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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