Cheap flights from MDT to SAT (Harrisburg Intl. to San Antonio Intl.)

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Cheap Flights from MDT to SAT starting at $179 One Way, $341 Round Trip

Prices starting at $341 for return flights and $179 for one-way flights to San Antonio Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, May 16 - Sat, May 23
MDT
Harrisburg
SAT
San Antonio
$341 Roundtrip, found 3 days ago
$341
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, May 16 from Harrisburg to San Antonio, returning Sat, May 23, priced at $341 found 3 days ago
Wed, Oct 7 - Tue, Oct 13
MDT
Harrisburg
SAT
San Antonio
$341 Roundtrip, found 6 days ago
$341
Roundtrip
found 6 days ago
Select United flight, departing Wed, Oct 7 from Harrisburg to San Antonio, returning Tue, Oct 13, priced at $341 found 6 days ago
Tue, Oct 6 - Mon, Oct 12
MDT
Harrisburg
SAT
San Antonio
$345 Roundtrip, found 6 hours ago
$345
Roundtrip
found 6 hours ago
Select Delta flight, departing Tue, Oct 6 from Harrisburg to San Antonio, returning Mon, Oct 12, priced at $345 found 6 hours ago
Wed, Aug 5 - Sun, Aug 9
MDT
Harrisburg
SAT
San Antonio
$349 Roundtrip, found 1 day ago
$349
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Aug 5 from Harrisburg to San Antonio, returning Sun, Aug 9, priced at $349 found 1 day ago
Wed, Nov 11 - Mon, Nov 16
MDT
Harrisburg
SAT
San Antonio
$355 Roundtrip, found 2 days ago
$355
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Nov 11 from Harrisburg to San Antonio, returning Mon, Nov 16, priced at $355 found 2 days ago

Hotel Ideas near San Antonio Intl.

Airport Hotels near San Antonio Intl.

Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport

3 out of 5
8818 Jones Maltsberger Rd San Antonio TX
$89 nightly
The price is $105 total per night from Apr 14 to Apr 15
$105 total
Apr 14 - Apr 15
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,370 reviews)
Pool was not open! We wished it had been noted on hotels.com. Staff is absolutely wonderful!

Reviewed on Apr 11, 2026

Wyndham Garden San Antonio Airport
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

2.5 out of 5
143 NE Loop 410 San Antonio TX
$79 nightly
The price is $93 total per night from May 3 to May 4
$93 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,678 reviews)
Great location

Reviewed on Apr 11, 2026

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Embassy Suites by Hilton San Antonio Airport

Embassy Suites by Hilton San Antonio Airport

3.5 out of 5
10110 U S Hwy 281 N San Antonio TX
$144 nightly
The price is $171 total per night from Apr 19 to Apr 20
$171 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, a free airport shuttle, and room service. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,113 reviews)
Great stay

Reviewed on Apr 11, 2026

Embassy Suites by Hilton San Antonio Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Antonio

Sonesta ES Suites San Antonio Downtown Alamo Plaza

Sonesta ES Suites San Antonio Downtown Alamo Plaza

3 out of 5
425 Bonham San Antonio TX
$93 nightly
The price is $110 total per night from May 4 to May 5
$110 total
May 4 - May 5
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,117 reviews)
The breakfast was fresh, but the menu never changed. When we arrived, the water wasn't working in the whole hotel, and we weren't told that until AFTER we paid for the room. That was the case with some other guests as well. The rooms were cleaned only upon request. The drainage in the shower was ...

Reviewed on Apr 10, 2026

Sonesta ES Suites San Antonio Downtown Alamo Plaza
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
$95 nightly
The price is $112 total per night from Apr 12 to Apr 13
$112 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (6,422 reviews)
Quite location on the riverwalk. The hotel is older but clean and the staff were really great.

Reviewed on Apr 11, 2026

Riverwalk Plaza
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

3 out of 5
105 S Saint Marys Street San Antonio TX
$136 nightly
The price is $161 total per night from Apr 19 to Apr 20
$161 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (4,467 reviews)
Room was clean and quiet even though we were very close to the elevators. WiFi was great.

Reviewed on Apr 11, 2026

Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Antonio Hotels With Airport Transportation

Hampton Inn & Suites San Antonio-Airport

Hampton Inn & Suites San Antonio-Airport

2.5 out of 5
8902 Jones Maltsberger Rd San Antonio TX
$84 nightly
The price is $99 total per night from Apr 19 to Apr 20
$99 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (1,954 reviews)
Breakfast was good, fresh and area was clean. Good parking. Front desk staff had no personality.

Reviewed on Apr 11, 2026

Hampton Inn & Suites San Antonio-Airport
Hilton Garden Inn San Antonio Airport South

Hilton Garden Inn San Antonio Airport South

3 out of 5
8505 Broadway Street San Antonio TX
$86 nightly
The price is $101 total per night from Apr 19 to Apr 20
$101 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,003 reviews)
It was an okay hotel. The AC sounded liked a car engine and parking fees seem unnecessary. Breakfast is not free.

Reviewed on Apr 2, 2026

Hilton Garden Inn San Antonio Airport South
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

2.5 out of 5
143 NE Loop 410 San Antonio TX
$79 nightly
The price is $93 total per night from May 3 to May 4
$93 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,678 reviews)
Great location

Reviewed on Apr 11, 2026

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Antonio Hotels

Days Inn by Wyndham San Antonio Alamo/Riverwalk

Days Inn by Wyndham San Antonio Alamo/Riverwalk

2 out of 5
400 Bowie Street San Antonio TX
$60 nightly
The price is $70 total per night from Apr 12 to Apr 13
$70 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff and ...
7.2/10 Good! (1,466 reviews)
There were cobwebs on the ceiling.

Reviewed on Apr 11, 2026

Days Inn by Wyndham San Antonio Alamo/Riverwalk
Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk

Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk

2.5 out of 5
1011 E Houston St San Antonio TX
$58 nightly
The price is $69 total per night from Apr 14 to Apr 15
$69 total
Apr 14 - Apr 15
Total with taxes and fees
Stay at this hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
7/10 Good! (1,899 reviews)
Everything was excellent . Only thing is the only thing wrong was that they require for their guests to pay for parking. You are already paying to stay in their facility guests shouldn’t be required to pay for parking .

Reviewed on Apr 11, 2026

Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk
Super 8 by Wyndham Universal City

Super 8 by Wyndham Universal City

2 out of 5
200 Palisades Dr Universal City TX
$43 nightly
The price is $49 total per night from May 6 to May 7
$49 total
May 6 - May 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Universal City. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Regal Live Oak and Olympia ...
6.8/10 (1,004 reviews)
Go value. Clean and very basic.

Reviewed on Mar 30, 2026

Super 8 by Wyndham Universal City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Antonio

Hyatt Regency Hill Country Resort and Villas

Hyatt Regency Hill Country Resort and Villas

4 out of 5
9800 Hyatt Resort Dr San Antonio TX
$445 nightly
The price is $526 total per night from Apr 19 to Apr 20
$526 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this golf hotel in San Antonio. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,000 reviews)

Families like: Outdoor pools, free waterpark access, playground, game room

Travelers say...
We had a great 3 nights of vacation at this property. My 5yr old daughter had a blast enjoying the lazy river and the warm pool, and so did I! It was great to have the pool set in a natural setting under trees, etc - beautiful experience. The lagoon was great too. I liked that they put together so ...

Reviewed on Apr 7, 2026

Hyatt Regency Hill Country Resort and Villas
Hotel Contessa

Hotel Contessa

4 out of 5
306 W Market Street San Antonio TX
$194 nightly
The price is $230 total per night from May 12 to May 13
$230 total
May 12 - May 13
Total with taxes and fees
Book a stay at this spa hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (3,521 reviews)
I travel a lot and I have to say this was one of the worst hotel experiences I have had in a long time. The hotel is run down. The AC was not working in the room we got and it was 89 degrees. We requested a different room, and was moved to a room without a river view but we were not reimbursed. The ...

Reviewed on Apr 11, 2026

Hotel Contessa
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

3 out of 5
105 S Saint Marys Street San Antonio TX
$136 nightly
The price is $161 total per night from Apr 19 to Apr 20
$161 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (4,467 reviews)
Room was clean and quiet even though we were very close to the elevators. WiFi was great.

Reviewed on Apr 11, 2026

Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MDT to SAT Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MDT Address & GPS
Address:
One Terminal Drive
Middletown PA, 17057
United States
IATA Code:
MDT
Longitude:
-76.756057
Latitude:
40.196008
Time Zone:
America/New_York
SAT Address & GPS
Address:
9800 Airport Boulevard
San Antonio TX, 78216
United States
IATA Code:
SAT
Longitude:
-98.472643
Latitude:
29.524937
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from MDT to San Antonio Airport?
Traveling from MDT to SAT means you'll need to change planes. But hey — there's no need to worry. American Airlines, Delta Air Lines and United Airlines offer flights with a single stopover.
What is the shortest flight from MDT to San Antonio Airport?
From Harrisburg, the wonderful sights and sounds of San Antonio are around 5 hours and 14 minutes away. Make sure you choose your favorite seat, or maybe even one with more legroom, and fly to your destination in total comfort.
How many hours flight from Harrisburg Intl. Airport to SAT?
Settle in and get comfy, because a typical plane trip from Harrisburg Intl. Airport to San Antonio Intl. Airport (SAT) is 5 hours and 19 minutes. Watch a few TV episodes, finish that book … You'll have plenty of time to sit back and enjoy the ride.
What airlines have the most flights from Harrisburg Intl. Airport (MDT) to San Antonio Intl. Airport (SAT)?
You'll need to make one or more stopovers if you're traveling from MDT to SAT. Right now, there are no airlines that advertise direct flights on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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