$126 Cheap flight deals from Columbus (CMH) to Key West (EYW)

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Airfares from $126 One Way, $228 Round Trip from Columbus to Key West

Prices starting at $228 for return flights and $126 for one-way flights to Key West were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 30 - Wed, Sep 3
CMH
Columbus
EYW
Key West
$228 Roundtrip, found 1 day ago
$228
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Aug 30 from Columbus to Key West, returning Wed, Sep 3, priced at $228 found 1 day ago
Fri, Aug 29 - Sat, Aug 30
CMH
Columbus
EYW
Key West
$229 Roundtrip, found 1 day ago
$229
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Aug 29 from Columbus to Key West, returning Sat, Aug 30, priced at $229 found 1 day ago
Sat, Aug 30 - Fri, Sep 5
CMH
Columbus
EYW
Key West
$232 Roundtrip, found 1 day ago
$232
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Aug 30 from Columbus to Key West, returning Fri, Sep 5, priced at $232 found 1 day ago
Sat, Aug 16 - Wed, Aug 20
CMH
Columbus
EYW
Key West
$251 Roundtrip, found 22 hours ago
$251
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Sat, Aug 16 from Columbus to Key West, returning Wed, Aug 20, priced at $251 found 22 hours ago
Tue, Aug 5 - Wed, Aug 6
CMH
Columbus
EYW
Key West
$254 Roundtrip, found 2 hours ago
$254
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Aug 5 from Columbus to Key West, returning Wed, Aug 6, priced at $254 found 2 hours ago

Key West economy flight packages

Price found within the past 48 hours. Click for updated prices.
Fitch Lodge - Key West Historic Inns
3.5-star property

Fitch Lodge - Key West Historic Inns

8.8/10 Excellent! (460 reviews)

Aug 29 - Aug 31

2 night stay

Columbus (CMH) to Key West (EYW)

American Airlines • Non-stop roundtrip • Coach
per person
found 1 day ago
My only complaint is. “Pet friendly” property shouldn’t charge $100 to bring said pet. A deposit fine, but otherwise it’s ripoff

Reviewed on Jun 21, 2024

Paradise Place by Avantstay Key West Old Town Condo w/ Shared Pool
3.0-star property

Paradise Place by Avantstay Key West Old Town Condo w/ Shared Pool

No reviews

Aug 30 - Sep 2

3 night stay

Columbus (CMH) to Key West (EYW)

Delta • Non-stop roundtrip • Coach
per person
found 3 hours ago
Spindrift House by Brightwild Huge Pool Dock
2.0-star property

Spindrift House by Brightwild Huge Pool Dock

No reviews

Aug 30 - Sep 2

3 night stay

Columbus (CMH) to Key West (EYW)

Delta • Non-stop roundtrip • Coach
Save 100% on your flight
per person
found 3 hours ago
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Key West packages with premium economy flights

Price found within the past 48 hours. Click for updated prices.
Southernmost Beach Resort and Guesthouses
4.0-star property

Southernmost Beach Resort and Guesthouses

8.6/10 Excellent! (2,611 reviews)

Aug 21 - Aug 24

3 night stay

Columbus (CMH) to Key West (EYW)

Delta • Non-stop roundtrip • PremiumEconomy
per person
found 1 day ago
Expansive resort and great location on the southern end. Clean with pleasant and helpful staff.

Reviewed on Jun 16, 2025

Orchid Key Inn - Adults Only
3.5-star property

Orchid Key Inn - Adults Only

9.8/10 Exceptional! (1,005 reviews)

Aug 21 - Aug 24

3 night stay

Columbus (CMH) to Key West (EYW)

Delta • Non-stop roundtrip • PremiumEconomy
per person
found 1 day ago
Great place. Very cool retro motel that’s been renovated. Room was a little small but very comfortable and clean. There’s a nice bar with great cocktails. Staff are friendly and attentive. The location was great. Central to everything and very walkable to most of the popular sites.

Reviewed on Jan 20, 2025

Almond Tree Inn Hotel - Adults Only
3.5-star property

Almond Tree Inn Hotel - Adults Only

10/10 Exceptional! (1,002 reviews)

Aug 21 - Aug 24

3 night stay

Columbus (CMH) to Key West (EYW)

Delta • Non-stop roundtrip • PremiumEconomy
per person
found 1 day ago
As always, Almond Tree Inn was a bright spot in our latest trip to Key West. I’ve stayed here several times over the years and everything about Almond Tree is top notch, from the superbly attentive and friendly staff to the well-appointed and maintained property. You always feel special staying here and this trip was no exception. As Florida locals, we look forward to our stays with you each and every time- THANK YOU!

Reviewed on May 26, 2025

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More About Flying To Key West from Columbus

Route Information for Flights from Columbus to Key West

Origin Airport IATA Code
CMH
Destination Airport IATA Code
EYW
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Columbus to Key West

Getting a spectacularly low fare on Columbus to Key West flights is always possible when you use Orbitz as your personal travel planner. Orbitz is your essential travel resource for low cost flights from Columbus to Key West, discount hotel accommodations, cheap car rentals, and more.

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Stay in Your Budget and Still Get Great Accommodations

Orbitz shoppers can access affordable vacation packages and have the option of booking their departure and arrival flights through different airlines, making travel less costly and more convenient. The best prices on flights from Columbus to Key Westare always found on Orbitz.

Frequently asked questions

Am I able to catch a flight from Columbus to Key West now?
Check out the Covid-19 Travel Advisor for the most useful info on travel restrictions and quarantine when getting a flight from Columbus to Key West.
What is the shortest flight from Columbus to Key West?
Traveling from John Glenn Columbus Intl. Airport (CMH) to EYW takes at least 3 hours and 17 minutes. Enjoy a tipple and get stuck into that book --- this is a great opportunity to sit back and chill out.
If I am not able to travel due to COVID-19, can I cancel my flight to Key West?
We get that traveling right now has its challenges, so it's good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Key West have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you'll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Key West with flexible change policies?
In most cases you'll have the option to reschedule your flight to Key West without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the "no change fees" filter and book with confidence.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2020 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data the cheapest month to fly is August. Perfect for those who need a weekend getaway, or just a break from it all before the weather changes. Be aware that the most expensive time to fly is the height of summer, with ticket prices peaking in the month of June.
How can I save money on flights?
To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you'll generally get a much better deal. Those who tried this on Orbitz in 2020 saved up to 45% on their airfares. Get mixing and matching today!

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.