Cheap flights from SNA to EYW (John Wayne to Key West Intl.)

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Cheap Flights from SNA to EYW starting at $464 One Way, $479 Round Trip

Prices starting at $479 for return flights and $464 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Apr 7 - Tue, Apr 13
SNA
Orange County
EYW
Key West
$479 Roundtrip, found 1 day ago
$479
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Apr 7 from Orange County to Key West, returning Tue, Apr 13, priced at $479 found 1 day ago
Wed, Apr 7 - Tue, Apr 13
SNA
Orange County
EYW
Key West
$537 Roundtrip, found 1 day ago
$537
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Apr 7 from Orange County to Key West, returning Tue, Apr 13, priced at $537 found 1 day ago
Wed, Apr 7 - Tue, Apr 13
SNA
Orange County
EYW
Key West
$563 Roundtrip, found 1 day ago
$563
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Apr 7 from Orange County to Key West, returning Tue, Apr 13, priced at $563 found 1 day ago
Wed, Apr 7 - Tue, Apr 13
SNA
Orange County
EYW
Key West
$609 Roundtrip, found 1 day ago
$609
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Apr 7 from Orange County to Key West, returning Tue, Apr 13, priced at $609 found 1 day ago
Wed, Apr 7 - Tue, Apr 13
SNA
Orange County
EYW
Key West
$612 Roundtrip, found 1 day ago
$612
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Apr 7 from Orange County to Key West, returning Tue, Apr 13, priced at $612 found 1 day ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
$210 nightly
The price is $236 total per night from Nov 28 to Nov 29
$236 total
Nov 28 - Nov 29
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,328 reviews)
"Place was beautiful, good way to end our Florida road trip . Hot tub is big and bar makes good drinks !"

Reviewed on Oct 30, 2026

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$188 nightly
The price is $212 total per night from Nov 30 to Dec 1
$212 total
Nov 30 - Dec 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$163 nightly
The price is $184 total per night from Nov 1 to Nov 2
$184 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
$285 nightly
The price is $321 total per night from Nov 1 to Nov 2
$321 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (1,801 reviews)
"It was great!"

Reviewed on Oct 30, 2026

Margaritaville Beach House Key West
Havana Cabana at Key West

Havana Cabana at Key West

4 out of 5
3420 N. Roosevelt Blvd Key West FL
$200 nightly
The price is $225 total per night from Nov 19 to Nov 20
$225 total
Nov 19 - Nov 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the helpful ...
Havana Cabana at Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$175 nightly
The price is $197 total per night from Nov 1 to Nov 2
$197 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,759 reviews)
"The floors were really dirty, had to keep shoes on and the sink wouldn't drain right"

Reviewed on Oct 30, 2026

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$163 nightly
The price is $184 total per night from Nov 1 to Nov 2
$184 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$188 nightly
The price is $212 total per night from Nov 30 to Dec 1
$212 total
Nov 30 - Dec 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
Hampton Inn Key West FL
Eden House

Eden House

4 out of 5
1015 Fleming St Key West FL
$183 nightly
The price is $206 total per night from Oct 31 to Nov 1
$206 total
Oct 31 - Nov 1
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,000 reviews)
"El hotel me gustó mucho además que está muy bueno, solo pienso que deben valorar ofertar desayuno"

Reviewed on Oct 26, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$204 nightly
The price is $229 total per night from Nov 18 to Nov 19
$229 total
Nov 18 - Nov 19
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,403 reviews)
"Just a few blocks from the ocean breeze. I’m not fond of all the walking in a hotel. I like small motels where you walk out the door to your car or pool. Nice little bar with entertainment at night. Walking distance to the Butterfly House, eating and shopping."

Reviewed on Oct 30, 2026

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$143 nightly
The price is $161 total per night from Nov 1 to Nov 2
$161 total
Nov 1 - Nov 2
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,000 reviews)
"I was excited to use the pool for our vacation, but it still wasn't inspected by the city so we couldn't use it for our 8 days there and it was upsetting. No compensation on the resort fee either."

Reviewed on Oct 26, 2026

Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$181 nightly
The price is $200 total per night from Nov 1 to Nov 2
$200 total
Nov 1 - Nov 2
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$263 nightly
The price is $296 total per night from Nov 15 to Nov 16
$296 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (3,630 reviews)
"The entire stay was perfect! See you next year!!"

Reviewed on Oct 29, 2026

Southernmost Beach Resort and Guesthouses
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$175 nightly
The price is $197 total per night from Nov 1 to Nov 2
$197 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,759 reviews)

Families like: Outdoor pools, playground, miniature golf, game room

Travelers say...
"The floors were really dirty, had to keep shoes on and the sink wouldn't drain right"

Reviewed on Oct 30, 2026

Blue Flamingo Resort Key West
Hilton Key West Resort & Marina

Hilton Key West Resort & Marina

4 out of 5
5950 Peninsular Avenue Key West FL
$178 nightly
The price is $201 total per night from Nov 15 to Nov 16
$201 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...
Hilton Key West Resort & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SNA to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
SNA Address & GPS
Address:
18601 Airport Way
Santa Ana CA, 92707
United States
IATA Code:
SNA
Longitude:
-117.860538
Latitude:
33.680201
Time Zone:
America/Los_Angeles
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from SNA to EYW?
As you can't fly straight from John Wayne Airport (SNA) to Key West Intl. Airport at the moment, a flight with a single stopover is your best bet. American Airlines, United Airlines and Delta Air Lines are all respected airlines that operate on this route.
What is the shortest flight from John Wayne Airport to EYW?
The shortest flight from SNA to Key West Intl. Airport (EYW) is 6 hours and 50 minutes. Pack a few things in your carry-on to keep you occupied, like a magazine or a sketch pad.
How many hours flight from John Wayne Airport (SNA) to Key West Intl. Airport (EYW)?
From John Wayne Airport to Key West Intl. Airport (EYW), you'll be cruising the skies for roughly 6 hours and 55 minutes. Get comfy, order a glass of wine and take out your noise-canceling earphones. It's time for a movie marathon.
What airlines have the most flights from John Wayne Airport to EYW?
Do some people-watching, grab a quick meal, stretch your legs … Airport stopovers don't have to be a bore! If you're planning to travel from Santa Ana to Key West, there are no direct flights. Plan to make at least one stop somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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