Cheap flights from SNA to EYW (John Wayne to Key West Intl.)

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Cheap Flights from SNA to EYW starting at $411 One Way, $757 Round Trip

Prices starting at $757 for return flights and $411 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Jun 22 - Thu, Jun 25
SNA
Orange County
EYW
Key West
$757 Roundtrip, found 1 day ago
$757
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jun 22 from Orange County to Key West, returning Thu, Jun 25, priced at $757 found 1 day ago
Sun, Aug 16 - Wed, Aug 19
SNA
Orange County
EYW
Key West
$782 Roundtrip, found 1 day ago
$782
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Aug 16 from Orange County to Key West, returning Wed, Aug 19, priced at $782 found 1 day ago
Mon, Jun 22 - Thu, Jun 25
SNA
Orange County
EYW
Key West
$806 Roundtrip, found 1 day ago
$806
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jun 22 from Orange County to Key West, returning Thu, Jun 25, priced at $806 found 1 day ago
Tue, Jun 16 - Mon, Jun 22
SNA
Orange County
EYW
Key West
$817 Roundtrip, found 3 days ago
$817
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Jun 16 from Orange County to Key West, returning Mon, Jun 22, priced at $817 found 3 days ago
Sun, Aug 16 - Wed, Aug 19
SNA
Orange County
EYW
Key West
$821 Roundtrip, found 1 day ago
$821
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Aug 16 from Orange County to Key West, returning Wed, Aug 19, priced at $821 found 1 day ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
$361 nightly
The price is $406 total per night from May 20 to May 21
$406 total
May 20 - May 21
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,084 reviews)
The property staff wasn’t as attentive as I would have hoped at a resort like this. The rooms were spacious and clean.

Reviewed on May 12, 2026

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$199 nightly
The price is $224 total per night from Jun 8 to Jun 9
$224 total
Jun 8 - Jun 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,352 reviews)
Firstly it was very close to the airport, secondly we loved our room, it was spacious, clean, updated, and the beds were comfortable with many pillow choices. We especially liked the back balcony The pool was wonderful, clean clear water, nice loungers and umbrellas, and the bar was perfect!

Reviewed on May 13, 2026

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$185 nightly
The price is $208 total per night from May 31 to Jun 1
$208 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,027 reviews)
It was wonderful! I would have appreciated an included breakfast, but it was fantastic overall. The free shuttle service to and from the airport was expedient. The free shuttle to and from downtown runs every hour and was very reliable.

Reviewed on May 13, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$202 nightly
The price is $227 total per night from Jun 3 to Jun 4
$227 total
Jun 3 - Jun 4
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,218 reviews)
Well run and kept. No complaints.

Reviewed on May 14, 2026

Blue Flamingo Resort Key West
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$305 nightly
The price is $343 total per night from Jun 3 to Jun 4
$343 total
Jun 3 - Jun 4
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,313 reviews)
This is a very nice property that has great amenities. The two big pools each have nice bars with them and you can charge what you get to your room so you don't have to take your wallet. They also give you your key card on a wristband so you don't have to worry about taking anything when you go to ...

Reviewed on May 13, 2026

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Boulevard Key West FL
$227 nightly
The price is $255 total per night from Jun 10 to Jun 11
$255 total
Jun 10 - Jun 11
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (1,818 reviews)
The view from our toom was obsteucted, parking area only. The beach is across the street from the resort, but they do have a fresh water shower at the front to rinse off. The beach area was nice, soft sand when we went for evening walks. They had lounge chairs with umbrellas for guests, not sure ...

Reviewed on May 12, 2026

Margaritaville Beach House Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$185 nightly
The price is $208 total per night from May 31 to Jun 1
$208 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,027 reviews)
It was wonderful! I would have appreciated an included breakfast, but it was fantastic overall. The free shuttle service to and from the airport was expedient. The free shuttle to and from downtown runs every hour and was very reliable.

Reviewed on May 13, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$199 nightly
The price is $224 total per night from Jun 8 to Jun 9
$224 total
Jun 8 - Jun 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,352 reviews)
Firstly it was very close to the airport, secondly we loved our room, it was spacious, clean, updated, and the beds were comfortable with many pillow choices. We especially liked the back balcony The pool was wonderful, clean clear water, nice loungers and umbrellas, and the bar was perfect!

Reviewed on May 13, 2026

Hampton Inn Key West FL
Eden House

Eden House

4 out of 5
1015 Fleming St Key West FL
$169 nightly
The price is $190 total per night from Jun 9 to Jun 10
$190 total
Jun 9 - Jun 10
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,002 reviews)
The outdoor arena was very nice and relaxing. The pool and hot tub was very good. The staff was very helpful and provided whatever we needed.

Reviewed on May 13, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$194 nightly
The price is $218 total per night from Jun 2 to Jun 3
$218 total
Jun 2 - Jun 3
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,343 reviews)
Parking fees extra. Resort fees added because used 3rd part booking. Breakfast was fresh. POOL was clean yet not award winning.

Reviewed on May 12, 2026

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$142 nightly
The price is $160 total per night from May 17 to May 18
$160 total
May 17 - May 18
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,007 reviews)
Great first impression the staff was so helpful. The room was nice and clean and air-conditioned. Will definitely stay there again.

Reviewed on May 12, 2026

Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$200 nightly
The price is $222 total per night from May 19 to May 20
$222 total
May 19 - May 20
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,037 reviews)
Nice place clean, good breakfast right on Duval for easy walk to everything

Reviewed on May 13, 2026

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$305 nightly
The price is $343 total per night from Jun 3 to Jun 4
$343 total
Jun 3 - Jun 4
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,313 reviews)
This is a very nice property that has great amenities. The two big pools each have nice bars with them and you can charge what you get to your room so you don't have to take your wallet. They also give you your key card on a wristband so you don't have to worry about taking anything when you go to ...

Reviewed on May 13, 2026

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
Book a stay at this beach hotel in Key West. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Popular attractions Duval Street and Smathers Beach ...
8.4/10 Very Good! (999 reviews)

Families like: Outdoor pool, babysitting, close to beach, bicycle rentals

Travelers say...
This is a beautiful resort full of amenities! Margaritas when you arrive, smoothies at the pool each day around noon, free airport and old town shuttles so we didn’t need to Uber anywhere, also coffee/water/cookies in the lobby daily. The beach is an easy walk across the street. The hotel is super ...

Reviewed on Apr 19, 2026

Get rates
Margaritaville Beach House Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$202 nightly
The price is $227 total per night from Jun 3 to Jun 4
$227 total
Jun 3 - Jun 4
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,218 reviews)

Families like: Outdoor pools, playground, miniature golf, game room

Travelers say...
Well run and kept. No complaints.

Reviewed on May 14, 2026

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SNA to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
SNA Address & GPS
Address:
18601 Airport Way
Santa Ana CA, 92707
United States
IATA Code:
SNA
Longitude:
-117.860538
Latitude:
33.680201
Time Zone:
America/Los_Angeles
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from SNA to EYW?
As you can't fly straight from John Wayne Airport (SNA) to Key West Intl. Airport at the moment, a flight with a single stopover is your best bet. American Airlines, United Airlines and Delta Air Lines are all respected airlines that operate on this route.
What is the shortest flight from John Wayne Airport to EYW?
The shortest flight from SNA to Key West Intl. Airport (EYW) is 6 hours and 50 minutes. Pack a few things in your carry-on to keep you occupied, like a magazine or a sketch pad.
How many hours flight from John Wayne Airport (SNA) to Key West Intl. Airport (EYW)?
From John Wayne Airport to Key West Intl. Airport (EYW), you'll be cruising the skies for roughly 6 hours and 55 minutes. Get comfy, order a glass of wine and take out your noise-canceling earphones. It's time for a movie marathon.
What airlines have the most flights from John Wayne Airport to EYW?
Do some people-watching, grab a quick meal, stretch your legs … Airport stopovers don't have to be a bore! If you're planning to travel from Santa Ana to Key West, there are no direct flights. Plan to make at least one stop somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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