Cheap flights from MHT to EYW (Manchester-Boston Regional to Key West Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from MHT to EYW starting at $355 One Way, $406 Round Trip

Prices starting at $406 for return flights and $355 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Jul 13 - Mon, Jul 20
MHT
Manchester
EYW
Key West
$406 Roundtrip, found 3 days ago
$406
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jul 13 from Manchester to Key West, returning Mon, Jul 20, priced at $406 found 3 days ago
Mon, Jul 13 - Mon, Jul 20
MHT
Manchester
EYW
Key West
$477 Roundtrip, found 3 days ago
$477
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jul 13 from Manchester to Key West, returning Mon, Jul 20, priced at $477 found 3 days ago
Mon, Jul 13 - Mon, Jul 20
MHT
Manchester
EYW
Key West
$508 Roundtrip, found 3 days ago
$508
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jul 13 from Manchester to Key West, returning Mon, Jul 20, priced at $508 found 3 days ago
Mon, Jul 13 - Mon, Jul 20
MHT
Manchester
EYW
Key West
$512 Roundtrip, found 3 days ago
$512
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jul 13 from Manchester to Key West, returning Mon, Jul 20, priced at $512 found 3 days ago
Mon, Jul 13 - Mon, Jul 20
MHT
Manchester
EYW
Key West
$553 Roundtrip, found 3 days ago
$553
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jul 13 from Manchester to Key West, returning Mon, Jul 20, priced at $553 found 3 days ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
$362 nightly
The price is $407 total per night from Jun 27 to Jun 28
$407 total
Jun 27 - Jun 28
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,103 reviews)
"The room and balcony were fantastic. The pool, grounds, and view of the ocean were lovely. The staff was super welcoming and friendly when we arrived. We enjoyed the close restaurant and walking path right across the street."

Reviewed on May 28, 2026

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$186 nightly
The price is $209 total per night from Jun 15 to Jun 16
$209 total
Jun 15 - Jun 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,381 reviews)
"Very nice location very nice hotel and stuff and free shuttle to town very recommended"

Reviewed on Jun 1, 2026

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$177 nightly
The price is $199 total per night from Jun 28 to Jun 29
$199 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,031 reviews)
"Overall, our stay was okay, but it did not quite meet the expectations we typically have for a Hilton property. There were several positive aspects of our visit. Check-in was smooth and efficient, the beds were comfortable, the complimentary cookies were a nice touch, and the bartender was friendly ..."

Reviewed on Jun 2, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$193 nightly
The price is $217 total per night from Jun 7 to Jun 8
$217 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,332 reviews)
"Nice property. Wonderful pools."

Reviewed on Jun 2, 2026

Blue Flamingo Resort Key West
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$261 nightly
The price is $294 total per night from Jun 8 to Jun 9
$294 total
Jun 8 - Jun 9
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,350 reviews)
"Are room was ok. There was an unusable beach. The smell was terrible. The restaurants were not kid friendly and made no effort to accommodate a 10 year old. Had 3 different menus and wouldn't cook anything that was on the bar menu that used the same kitchen. All kinds of additional fees at checkout. ..."

Reviewed on Jun 1, 2026

Southernmost Beach Resort and Guesthouses
Hilton Garden Inn Key West / The Keys Collection

Hilton Garden Inn Key West / The Keys Collection

3.5 out of 5
3850 N Roosevelt Blvd Key West FL
$144 nightly
The price is $162 total per night from Jun 22 to Jun 23
$162 total
Jun 22 - Jun 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy 2 restaurants, breakfast (surcharge), and a free area shuttle. Our guests praise the pool and ...
8/10 Very Good! (1,237 reviews)
"Great Stay with Excellent Shuttle Service! We recently stayed for 1 night during our Key West vacation and had a very pleasant experience overall. Location – The hotel is conveniently located close to the Key West downtown area. What really stood out was the complimentary shuttle service that runs ..."

Reviewed on Jun 1, 2026

Hilton Garden Inn Key West / The Keys Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$177 nightly
The price is $199 total per night from Jun 28 to Jun 29
$199 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,031 reviews)
"Overall, our stay was okay, but it did not quite meet the expectations we typically have for a Hilton property. There were several positive aspects of our visit. Check-in was smooth and efficient, the beds were comfortable, the complimentary cookies were a nice touch, and the bartender was friendly ..."

Reviewed on Jun 2, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$186 nightly
The price is $209 total per night from Jun 15 to Jun 16
$209 total
Jun 15 - Jun 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,381 reviews)
"Very nice location very nice hotel and stuff and free shuttle to town very recommended"

Reviewed on Jun 1, 2026

Hampton Inn Key West FL
Eden House

Eden House

4 out of 5
1015 Fleming St Key West FL
$159 nightly
The price is $179 total per night from Jul 2 to Jul 3
$179 total
Jul 2 - Jul 3
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,002 reviews)
"I liked"

Reviewed on Jun 1, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$164 nightly
The price is $185 total per night from Jun 3 to Jun 4
$185 total
Jun 3 - Jun 4
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,340 reviews)
"The rooms are nice. They provide necessary amenities and are cleaned well. Not a lot of space, but fair for a motel setting. There is loud music next door at a bar, which I enjoyed, but that’s something to be aware of if you’re a light sleeper. The staff was helpful and this area of the island was ..."

Reviewed on May 31, 2026

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$131 nightly
The price is $147 total per night from Jun 4 to Jun 5
$147 total
Jun 4 - Jun 5
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,002 reviews)
"Staff members were very good ."

Reviewed on Jun 1, 2026

Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$201 nightly
The price is $223 total per night from Jun 8 to Jun 9
$223 total
Jun 8 - Jun 9
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,035 reviews)
"I would highly recommend this hotel from the friendly staff, to the pool, lovely gardens and delicious fresh breakfast. The location is easily walkable to all of Key West attractions but very quiet and relaxing."

Reviewed on May 31, 2026

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$261 nightly
The price is $294 total per night from Jun 8 to Jun 9
$294 total
Jun 8 - Jun 9
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,350 reviews)
"Are room was ok. There was an unusable beach. The smell was terrible. The restaurants were not kid friendly and made no effort to accommodate a 10 year old. Had 3 different menus and wouldn't cook anything that was on the bar menu that used the same kitchen. All kinds of additional fees at checkout. ..."

Reviewed on Jun 1, 2026

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
Book a stay at this beach hotel in Key West. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Popular attractions Duval Street and Smathers Beach ...
8.4/10 Very Good! (999 reviews)

Families like: Outdoor pool, babysitting, close to beach, bicycle rentals

Travelers say...
"This is a beautiful resort full of amenities! Margaritas when you arrive, smoothies at the pool each day around noon, free airport and old town shuttles so we didn’t need to Uber anywhere, also coffee/water/cookies in the lobby daily. The beach is an easy walk across the street. The hotel is super ..."

Reviewed on Apr 19, 2026

Get rates
Margaritaville Beach House Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$193 nightly
The price is $217 total per night from Jun 7 to Jun 8
$217 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,332 reviews)

Families like: Outdoor pools, playground, miniature golf, game room

Travelers say...
"Nice property. Wonderful pools."

Reviewed on Jun 2, 2026

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MHT to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MHT Address & GPS
Address:
One Airport Road
Manchester NH, 03103
United States
IATA Code:
MHT
Longitude:
-71.438439
Latitude:
42.927862
Time Zone:
America/New_York
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Manchester-Boston Regional Airport (MHT) to Key West Intl. Airport (EYW)?
As you can't fly nonstop from Manchester-Boston Regional Airport (MHT) to Key West Intl. Airport (EYW) at the moment, a flight with just one stop is the next best thing. American Airlines, United Airlines and JetBlue Airways are popular airlines that service this route.
What is the shortest flight from Manchester Airport to Key West Intl. Airport (EYW)?
Getting from Manchester Airport to Key West Intl. Airport takes at least 4 hours and 58 minutes. Enjoy a tipple and get stuck into that book — this is your chance to sit back and unwind.
How many hours flight from MHT to Key West Intl. Airport?
It typically takes about 5 hours and 3 minutes to get from Manchester-Boston Regional Airport (MHT) to EYW. You'll be in the sky for a decent amount of time, so contemplate bringing plenty of entertainment, like an engrossing book or a podcast.
What airlines have the most flights from Manchester Airport to Key West Intl. Airport?
For now, you won't find any direct flights between MHT and EYW. However, you will find flights with at least one stop. There's always a positive side — use the time to get the blood flowing again or do a little souvenir shopping!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore