Cheap flights from MSP to EYW (Minneapolis - St. Paul Intl. to Key West Intl.)

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Cheap Flights from MSP to EYW starting at $290 One Way, $369 Round Trip

Prices starting at $369 for return flights and $290 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Nov 11 - Wed, Nov 18
MSP
Minneapolis
EYW
Key West
$369 Roundtrip, found 10 hours ago
$369
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Nov 11 from Minneapolis to Key West, returning Wed, Nov 18, priced at $369 found 10 hours ago
Wed, Nov 11 - Wed, Nov 18
MSP
Minneapolis
EYW
Key West
$369 Roundtrip, found 10 hours ago
$369
Roundtrip
found 10 hours ago
Select United flight, departing Wed, Nov 11 from Minneapolis to Key West, returning Wed, Nov 18, priced at $369 found 10 hours ago
Wed, May 13 - Wed, May 20
MSP
Minneapolis
EYW
Key West
$377 Roundtrip, found 3 hours ago
$377
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Wed, May 13 from Minneapolis to Key West, returning Wed, May 20, priced at $377 found 3 hours ago
Tue, May 5 - Wed, May 13
MSP
Minneapolis
EYW
Key West
$394 Roundtrip, found 3 days ago
$394
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, May 5 from Minneapolis to Key West, returning Wed, May 13, priced at $394 found 3 days ago
Wed, Nov 11 - Wed, Nov 18
MSP
Minneapolis
EYW
Key West
$399 Roundtrip, found 10 hours ago
$399
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Nov 11 from Minneapolis to Key West, returning Wed, Nov 18, priced at $399 found 10 hours ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
$422 nightly
The price is $474 total per night from May 21 to May 22
$474 total
May 21 - May 22
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,050 reviews)
Great

Reviewed on Apr 22, 2026

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$246 nightly
The price is $276 total per night from May 18 to May 19
$276 total
May 18 - May 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,336 reviews)
Love it

Reviewed on Apr 23, 2026

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$221 nightly
The price is $249 total per night from May 18 to May 19
$249 total
May 18 - May 19
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,009 reviews)
restaurant was great!

Reviewed on Apr 22, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$229 nightly
The price is $258 total per night from Apr 26 to Apr 27
$258 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,123 reviews)
Great location, clean facility.

Reviewed on Apr 23, 2026

Blue Flamingo Resort Key West
Beachside Resort & Residences

Beachside Resort & Residences

3.5 out of 5
3841 N Roosevelt Blvd Key West FL
$259 nightly
The price is $292 total per night from May 12 to May 13
$292 total
May 12 - May 13
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 2 restaurants, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
8.6/10 Excellent! (2,167 reviews)
Enjoyed our stay

Reviewed on Apr 23, 2026

Beachside Resort & Residences
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Boulevard Key West FL
$265 nightly
The price is $298 total per night from May 20 to May 21
$298 total
May 20 - May 21
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (1,812 reviews)
Very nice vibe to the lobby are and the entire resort. Food was good, pool area very well maintained

Reviewed on Apr 22, 2026

Margaritaville Beach House Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$221 nightly
The price is $249 total per night from May 18 to May 19
$249 total
May 18 - May 19
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,009 reviews)
restaurant was great!

Reviewed on Apr 22, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$246 nightly
The price is $276 total per night from May 18 to May 19
$276 total
May 18 - May 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,336 reviews)
Love it

Reviewed on Apr 23, 2026

Hampton Inn Key West FL
Eden House

Eden House

4 out of 5
1015 Fleming St Key West FL
$227 nightly
The price is $255 total per night from May 18 to May 19
$255 total
May 18 - May 19
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,002 reviews)
The aircon is very very noisy which in turn means neighbours TV’s are extremely loud, I would imagine to drown out the noise of the aircon. You couldn’t swing a cat in the room, there is no wardrobe/nowhere to hang clothes and if you have a full sized suitcase then there is no room whatsoever. Eden ...

Reviewed on Apr 21, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$252 nightly
The price is $284 total per night from May 10 to May 11
$284 total
May 10 - May 11
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,317 reviews)
The room was ready but staff would not allow us to check in early because we booked on Expedia. The water pressure was the worst I have ever experienced. The ac unit was rusty and leaked water. The entire room smelled like the sewer. Staff member was leaf blowing right outside our room at 6:00 ...

Reviewed on Apr 22, 2026

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$197 nightly
The price is $222 total per night from May 10 to May 11
$222 total
May 10 - May 11
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,006 reviews)
Location! Location! Location! Seashell was a best-kept secret. It was a great deal for being so walkably close to downtown Key West and, to be honest, it looked a bit sketch from the street (faded paint and sign, construction company sign on a building, signs of construction) but the guy checking ...

Reviewed on Apr 19, 2026

Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$220 nightly
The price is $244 total per night from Apr 27 to Apr 28
$244 total
Apr 27 - Apr 28
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,022 reviews)
Is a great location

Reviewed on Apr 22, 2026

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$330 nightly
The price is $372 total per night from May 19 to May 20
$372 total
May 19 - May 20
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,236 reviews)
We originally booked a king room in Avalon. This is a very small room if you like us were travelling with 2 large suitcases. The room was clean just small. We asked if we could upgrade and having spent one night in this room we moved to a king room on the sunset rooms on the beach. This room was ...

Reviewed on Apr 23, 2026

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
Book a stay at this beach hotel in Key West. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Popular attractions Duval Street and Smathers Beach ...
8.4/10 Very Good! (999 reviews)

Families like: Outdoor pool, babysitting, close to beach, bicycle rentals

Travelers say...
This is a beautiful resort full of amenities! Margaritas when you arrive, smoothies at the pool each day around noon, free airport and old town shuttles so we didn’t need to Uber anywhere, also coffee/water/cookies in the lobby daily. The beach is an easy walk across the street. The hotel is super ...

Reviewed on Apr 19, 2026

Get rates
Margaritaville Beach House Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$229 nightly
The price is $258 total per night from Apr 26 to Apr 27
$258 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,123 reviews)

Families like: Outdoor pools, playground, miniature golf, game room

Travelers say...
Great location, clean facility.

Reviewed on Apr 23, 2026

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MSP to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MSP Address & GPS
Address:
6040 28th Avenue South
Minneapolis MN, 55450
United States
IATA Code:
MSP
Longitude:
-93.210922
Latitude:
44.883016
Time Zone:
America/Chicago
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from MSP to EYW?
Unfortunately, nonstop flights aren't an option when traveling from Wold–Chamberlain Field to Key West Intl. Airport. However, there are several carriers that service this route with only one simple stopover, including American Airlines, Delta Air Lines and United Airlines.
What is the shortest flight from MSP to Key West Intl. Airport?
The shortest flight time from Minneapolis - St. Paul Intl. Airport (MSP) to Key West Intl. Airport (EYW) is around 5 hours and 35 minutes. Grab a refreshment from the drink cart, start your travel journal or get to know your neighbors — you'll have enough time on this medium-haul trip.
How many hours flight from Wold–Chamberlain Field to EYW?
The journey from MSP to EYW will take an average of 5 hours and 39 minutes. A few good movies, some light reading and a little shut-eye will help make time fly.
What airlines have the most flights from Minneapolis - St. Paul Intl. Airport (MSP) to EYW?
If you want to find an airline that operates direct flights from Wold–Chamberlain Field to EYW, you're out of luck. You'll need to book a flight with at least one stopover to get to Key West.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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