Cheap flights from MSP to EYW (Minneapolis - St. Paul Intl. to Key West Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from MSP to EYW starting at $205 One Way, $379 Round Trip

Prices starting at $379 for return flights and $205 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Jan 27 - Tue, Feb 2
MSP
Minneapolis
EYW
Key West
$379 Roundtrip, found 8 hours ago
$379
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Jan 27 from Minneapolis to Key West, returning Tue, Feb 2, priced at $379 found 8 hours ago
Mon, Jan 11 - Sat, Jan 16
MSP
Minneapolis
EYW
Key West
$389 Roundtrip, found 2 days ago
$389
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Jan 11 from Minneapolis to Key West, returning Sat, Jan 16, priced at $389 found 2 days ago
Wed, Jan 27 - Tue, Feb 2
MSP
Minneapolis
EYW
Key West
$394 Roundtrip, found 8 hours ago
$394
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Jan 27 from Minneapolis to Key West, returning Tue, Feb 2, priced at $394 found 8 hours ago
Fri, Dec 4 - Wed, Dec 9
MSP
Minneapolis
EYW
Key West
$404 Roundtrip, found 5 days ago
$404
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Dec 4 from Minneapolis to Key West, returning Wed, Dec 9, priced at $404 found 5 days ago
Wed, Dec 16 - Sat, Dec 19
MSP
Minneapolis
EYW
Key West
$407 Roundtrip, found 3 days ago
$407
Roundtrip
found 3 days ago
Select United flight, departing Wed, Dec 16 from Minneapolis to Key West, returning Sat, Dec 19, priced at $407 found 3 days ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
$230 nightly
The price is $259 total per night from Oct 31 to Nov 1
$259 total
Oct 31 - Nov 1
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,319 reviews)
"our second time. we had to wait a few hours for our room to be ready, and the room they gave us was next to some noisy partygoers. had to complain the next day to ask for another room elsewhere and they eventually moved us, but only after alot of prodding. The vibe and atmosphere was different, so ..."

Reviewed on Oct 13, 2026

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$169 nightly
The price is $190 total per night from Oct 25 to Oct 26
$190 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$157 nightly
The price is $177 total per night from Oct 25 to Oct 26
$177 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,119 reviews)
"Beautiful resort. Very good restaurant on site. Shuttle bus to and from Old Town Key West every hour. The staff was exceptional. Highly recommend this resort."

Reviewed on Oct 13, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
$265 nightly
The price is $298 total per night from Oct 15 to Oct 16
$298 total
Oct 15 - Oct 16
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (1,802 reviews)
"The smell from the seaweed was disgusting !!!"

Reviewed on Oct 14, 2026

Margaritaville Beach House Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$175 nightly
The price is $197 total per night from Oct 15 to Oct 16
$197 total
Oct 15 - Oct 16
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,724 reviews)
"Grounds were kept clean, room was filthy. Never cleaned while we were there, and they left new towels in a bag attached to room door handle outside."

Reviewed on Oct 14, 2026

Blue Flamingo Resort Key West
Beachside Resort & Residences

Beachside Resort & Residences

3.5 out of 5
3841 N Roosevelt Blvd Key West FL
$202 nightly
The price is $227 total per night from Oct 15 to Oct 16
$227 total
Oct 15 - Oct 16
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 2 restaurants, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
Beachside Resort & Residences
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$157 nightly
The price is $177 total per night from Oct 25 to Oct 26
$177 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,119 reviews)
"Beautiful resort. Very good restaurant on site. Shuttle bus to and from Old Town Key West every hour. The staff was exceptional. Highly recommend this resort."

Reviewed on Oct 13, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$169 nightly
The price is $190 total per night from Oct 25 to Oct 26
$190 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
Hampton Inn Key West FL
Eden House

Eden House

4 out of 5
1015 Fleming St Key West FL
$168 nightly
The price is $189 total per night from Oct 28 to Oct 29
$189 total
Oct 28 - Oct 29
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,000 reviews)
"Amazing staff, beautiful location, super clean rooms and great amenities. This is my 3rd stay here and will definitely be back again!"

Reviewed on Oct 12, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$169 nightly
The price is $190 total per night from Oct 15 to Oct 16
$190 total
Oct 15 - Oct 16
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,388 reviews)
"I came here for a quick solo getaway to relax, and unfortunately, I would not recommend Southwinds Motel. When I arrived on Saturday, October 10, they initially gave me a room right next to the bar. It was so loud that I had to request another room, and I didn’t finally get settled until around 4 ..."

Reviewed on Oct 14, 2026

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$124 nightly
The price is $140 total per night from Oct 15 to Oct 16
$140 total
Oct 15 - Oct 16
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,005 reviews)
"It's a no frills hotel. But it was clean and comfortable. And maybe the best value on Key West."

Reviewed on Oct 14, 2026

Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$203 nightly
The price is $225 total per night from Oct 25 to Oct 26
$225 total
Oct 25 - Oct 26
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.6/10 Exceptional! (1,120 reviews)
"Na"

Reviewed on Oct 13, 2026

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$225 nightly
The price is $253 total per night from Oct 25 to Oct 26
$253 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy 3 outdoor pools, a full-service spa, and 2 poolside bars. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (3,632 reviews)
"Great location. Friendly staff"

Reviewed on Oct 14, 2026

Southernmost Beach Resort and Guesthouses
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$175 nightly
The price is $197 total per night from Oct 15 to Oct 16
$197 total
Oct 15 - Oct 16
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,724 reviews)

Families like: Outdoor pools, playground, miniature golf, game room

Travelers say...
"Grounds were kept clean, room was filthy. Never cleaned while we were there, and they left new towels in a bag attached to room door handle outside."

Reviewed on Oct 14, 2026

Blue Flamingo Resort Key West
Hilton Key West Resort & Marina

Hilton Key West Resort & Marina

4 out of 5
5950 Peninsular Avenue Key West FL
$174 nightly
The price is $196 total per night from Oct 27 to Oct 28
$196 total
Oct 27 - Oct 28
Total with taxes and fees
Book a stay at this luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...
9/10 Wonderful! (1,791 reviews)
"We went to Duval Street and Town Everyday, The Hilton KW Resort & Marina Shuttle Driver “Fausto” was a 15 Star!! He was so accommodating, professional, helpful people person, on time and just a Genuine Nice Guy! Wish everyone that we meant was like him!! Top Notch!!!!!👏👏🙌🙌 🌟🌟💫"

Reviewed on Oct 13, 2026

Hilton Key West Resort & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MSP to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MSP Address & GPS
Address:
6040 28th Avenue South
Minneapolis MN, 55450
United States
IATA Code:
MSP
Longitude:
-93.210922
Latitude:
44.883016
Time Zone:
America/Chicago
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from MSP to EYW?
Unfortunately, nonstop flights aren't an option when traveling from Wold–Chamberlain Field to Key West Intl. Airport. However, there are several carriers that service this route with only one simple stopover, including American Airlines, Delta Air Lines and United Airlines.
What is the shortest flight from MSP to Key West Intl. Airport?
The shortest flight time from Minneapolis - St. Paul Intl. Airport (MSP) to Key West Intl. Airport (EYW) is around 5 hours and 35 minutes. Grab a refreshment from the drink cart, start your travel journal or get to know your neighbors — you'll have enough time on this medium-haul trip.
How many hours flight from Wold–Chamberlain Field to EYW?
The journey from MSP to EYW will take an average of 5 hours and 39 minutes. A few good movies, some light reading and a little shut-eye will help make time fly.
What airlines have the most flights from Minneapolis - St. Paul Intl. Airport (MSP) to EYW?
If you want to find an airline that operates direct flights from Wold–Chamberlain Field to EYW, you're out of luck. You'll need to book a flight with at least one stopover to get to Key West.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore