$129 Cheap flight deals from Chicago (CHI) to West Knoxville (TYS)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Chicago to West Knoxville

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Oct 4 - Tue, Oct 7
MDW
Midway Intl.
TYS
McGhee Tyson
$286 Roundtrip, found 2 days ago
$286
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Oct 4 from Midway Intl. to McGhee Tyson, returning Tue, Oct 7, priced at $286 found 2 days ago
Fri, Oct 3 - Wed, Oct 8
ORD
O'Hare Intl.
TYS
McGhee Tyson
$322 Roundtrip, found 2 days ago
$322
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Oct 3 from O'Hare Intl. to McGhee Tyson, returning Wed, Oct 8, priced at $322 found 2 days ago

Airfares from $129 One Way, $188 Round Trip from Chicago to West Knoxville

Prices starting at $188 for return flights and $129 for one-way flights to West Knoxville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Dec 5 - Sun, Dec 7
RFD
Rockford
TYS
Knoxville
$188 Roundtrip, found 1 day ago
$188
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Dec 5 from Rockford to Knoxville, returning Sun, Dec 7, priced at $188 found 1 day ago
Fri, Dec 5 - Sun, Dec 7
ORD
Chicago
TYS
Knoxville
$189 Roundtrip, found 1 day ago
$189
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Dec 5 from Chicago to Knoxville, returning Sun, Dec 7, priced at $189 found 1 day ago
Sun, Oct 19 - Sat, Oct 25
ORD
Chicago
TYS
Knoxville
$198 Roundtrip, found 17 hours ago
$198
Roundtrip
found 17 hours ago
Select United flight, departing Sun, Oct 19 from Chicago to Knoxville, returning Sat, Oct 25, priced at $198 found 17 hours ago
Wed, Oct 15 - Sat, Oct 18
ORD
Chicago
TYS
Knoxville
$202 Roundtrip, found 13 hours ago
$202
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Oct 15 from Chicago to Knoxville, returning Sat, Oct 18, priced at $202 found 13 hours ago
Mon, Dec 15 - Sun, Dec 21
MDW
Chicago
TYS
Knoxville
$209 Roundtrip, just found
$209
Roundtrip
just found
Select Delta flight, departing Mon, Dec 15 from Chicago to Knoxville, returning Sun, Dec 21, priced at $209 just found

West Knoxville economy flight packages

Price found within the past 48 hours. Click for updated prices.
Cumberland House Knoxville, Tapestry Collection by Hilton
3.0-star property

Cumberland House Knoxville, Tapestry Collection by Hilton

9.2/10 Wonderful! (1,001 reviews)

Nov 20 - Nov 24

4 night stay

Chicago (ORD) to Knoxville (TYS)

American Airlines • Roundtrip • Coach
Price was $659, price is now $479 per person
$479
per person
found 1 day ago
Currently under construction so entry and egress can be confusing, my stay was otherwise perfect. Great value.

Reviewed on Feb 7, 2025

The Oliver Hotel
3.5-star property

The Oliver Hotel

9.6/10 Exceptional! (609 reviews)

Nov 20 - Nov 24

4 night stay

Chicago (ORD) to Knoxville (TYS)

American Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $808, price is now $535 per person
$535
per person
found 1 day ago
The Oliver Hotel in Knoxville is right on the square in downtown. It is advertised as a 'boutique' hotel and that is a perfect description of the hotel. I was allowed to check in early, and upon my request for an upgrade to my room booking at a nominal cost, I was upgraded at no charge. The hotel seems to be a renovated property, and the rooms are outfitted in a 70's motif, with brass dome lights and decor. The bed was very comfortable, and the bathroom classically stylish. The water pressure in the shower left something to be desired, and that is often a result of an older structure renovation. The rooms are not exactly soundproof, other guests can occasionally be heard. The only criticism of the room are the bath linens; an upgrade would put this hotel another notch up, There is no swimming pool nor fitness center, again indicative of a boutique hotel. The staff was accommodating, and stretched thin; the front desk staff seem to perform numerous functions such as typical front desk activities, to running the valet, to accommodating guest requests. Often there is a sign on the desk explaining this and a promise to 'be right back'. In all instances this was the case, the desk is not unmanned for long. There are bicycles guests can check out for free. The room attendants did a great job, my room was cleaned daily. Great stay, accommodating snd friendly staff, and hidden behind a slide door is the Peter Kern Library, a speakeasy bar where you will share booths.

Reviewed on Jun 17, 2025

THE TENNESSEAN Hotel
4.0-star property

THE TENNESSEAN Hotel

9.4/10 Exceptional! (1,003 reviews)

Nov 20 - Nov 24

4 night stay

Chicago (ORD) to Knoxville (TYS)

American Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $829, price is now $586 per person
$586
per person
found 1 day ago
The staff are very good.

Reviewed on Aug 31, 2025

Don't see what you're looking for?
See all available trips from Chicago to West Knoxville
View all trips

More About Flying To West Knoxville from Chicago

Route Information for Flights from Chicago to West Knoxville

Origin Airport IATA Code
CHI
Destination Airport IATA Code
TYS
Distance
475 mi
Direct Flight Airlines
American Airlines, Qatar Airways, Air Canada, JAL, Aer Lingus, Emirates, Air New Zealand, United Airlines, Alaska Airlines, Avianca, Royal Jordanian, ANA, Lufthansa, British Airways
Earliest Flight Arrival
2:10PM UTC
Latest Flight Arrival
2:50AM UTC

Chicago to West Knoxville

Score low fares on flights from Chicago to West Knoxville with Orbitz. We make it easier than ever to find cheap Chicago to West Knoxville flights with our cutting-edge mobile tools and mobile website.

Book Discount Flights From Chicago to West Knoxville in Minutes

If you are looking for low cost Chicago to West Knoxville flights, just skip all of the other so-called bargain travel sites, because Orbitz offers guaranteed low fares. That means you don't have to constantly scan multiple sites and hover like a vulture at your computer, hoping to score better deals through last-minute sales.

Find Bargain Chicago to West Knoxville Flights With Our Convenient Tools

You benefit from more than just cheap flights from Chicago to West Knoxville. Orbitz is a convenient one-stop trip planner. Research weather, attractions, and transportation options for West Knoxville to help you plan your trip and decide what to pack and where to go.

Booking domestic or international air fare and accommodations with Orbitz is a snap. Use your iPad, iPhone or Android device to find discount flights from Chicago to West Knoxville even while on the move, and sign up for instant email and text alerts to stay up-to-date on any delays affecting your flight. Or access m.orbitz.com via your mobile device’s Web browser.

Earn Miles through Orbitz for Your Frequent Flyer Program

You don't have to give up frequent flyer points to take advantage of our low fares. Add your frequent flyer number when you book your Chicago to West Knoxville flights to receive credit for your trip.

More Destinations

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.