$107 Cheap flight deals from Myrtle Beach (MYR) to Knoxville (TYS)

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Airfares from $107 One Way, $199 Round Trip from Myrtle Beach to Knoxville

Prices starting at $199 for return flights and $107 for one-way flights to Knoxville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jul 4 - Sat, Jul 5
MYR
Myrtle Beach
TYS
Knoxville
$199 Roundtrip, found 2 days ago
$199
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Jul 4 from Myrtle Beach to Knoxville, returning Sat, Jul 5, priced at $199 found 2 days ago
Tue, Jun 24 - Tue, Jul 1
MYR
Myrtle Beach
TYS
Knoxville
$214 Roundtrip, found 6 days ago
$214
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Jun 24 from Myrtle Beach to Knoxville, returning Tue, Jul 1, priced at $214 found 6 days ago
Fri, Jul 4 - Tue, Jul 8
MYR
Myrtle Beach
TYS
Knoxville
$214 Roundtrip, found 2 days ago
$214
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Jul 4 from Myrtle Beach to Knoxville, returning Tue, Jul 8, priced at $214 found 2 days ago
Mon, Jun 23 - Tue, Jul 1
MYR
Myrtle Beach
TYS
Knoxville
$217 Roundtrip, found 6 days ago
$217
Roundtrip
found 6 days ago
Select Delta flight, departing Mon, Jun 23 from Myrtle Beach to Knoxville, returning Tue, Jul 1, priced at $217 found 6 days ago
Fri, Aug 22 - Sun, Aug 24
MYR
Myrtle Beach
TYS
Knoxville
$229 Roundtrip, found 5 hours ago
$229
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Fri, Aug 22 from Myrtle Beach to Knoxville, returning Sun, Aug 24, priced at $229 found 5 hours ago

More About Flying To Knoxville from Myrtle Beach

Route Information for Flights from Myrtle Beach to Knoxville

Origin Airport IATA Code
MYR
Destination Airport IATA Code
TYS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Myrtle Beach to Knoxville

The best fares for Myrtle Beach to Knoxville flights are always found on Orbitz. With superior discounts and the latest innovations in mobile access, your ideal trip starts with Orbitz.

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Our iPhone and Android mobile apps can be used to compare and book flights from Myrtle Beach to Knoxville. These apps are perfect for checking the status of flights, gate and baggage claims details, car rental rates, and for receiving alerts on special savings that are exclusive to mobile users. Mobile app users can even score great rates when booking hotel rooms. You can compare hotels, virtually view photo galleries, and check out user reviews using the app, as well as find out which ones are closest to you.

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Frequently asked questions

What is the shortest flight from Myrtle Beach to Knoxville?
It can take as little as 2 hours and 3 minutes to get from Myrtle Beach Intl. Airport to Knoxville Airport. Kick back and enjoy the trip, because you’ll be coming in to land in the blink of an eye.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.