Cheap flights from ORD to TYS (O'Hare Intl. to McGhee Tyson)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from ORD to TYS starting at $105 One Way, $189 Round Trip

Prices starting at $189 for return flights and $105 for one-way flights to McGhee Tyson were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Jun 4 - Mon, Jun 8
ORD
Chicago
TYS
Knoxville
$189 Roundtrip, found 13 hours ago
$189
Roundtrip
found 13 hours ago
Select United flight, departing Thu, Jun 4 from Chicago to Knoxville, returning Mon, Jun 8, priced at $189 found 13 hours ago
Fri, Apr 17 - Sun, Apr 19
ORD
Chicago
TYS
Knoxville
$194 Roundtrip, found 2 days ago
$194
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Apr 17 from Chicago to Knoxville, returning Sun, Apr 19, priced at $194 found 2 days ago
Thu, Apr 9 - Sat, Apr 11
ORD
Chicago
TYS
Knoxville
$196 Roundtrip, found 19 hours ago
$196
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Thu, Apr 9 from Chicago to Knoxville, returning Sat, Apr 11, priced at $196 found 19 hours ago
Sat, Jul 11 - Thu, Jul 16
ORD
Chicago
TYS
Knoxville
$198 Roundtrip, found 17 hours ago
$198
Roundtrip
found 17 hours ago
Select United flight, departing Sat, Jul 11 from Chicago to Knoxville, returning Thu, Jul 16, priced at $198 found 17 hours ago
Fri, Apr 3 - Mon, Apr 6
ORD
Chicago
TYS
Knoxville
$204 Roundtrip, found 1 day ago
$204
Roundtrip
found 1 day ago
Select United flight, departing Fri, Apr 3 from Chicago to Knoxville, returning Mon, Apr 6, priced at $204 found 1 day ago

Hotel Ideas near McGhee Tyson

Airport Hotels near McGhee Tyson

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$85 nightly
The price is $100 total per night from Feb 21 to Feb 22
$100 total
Feb 21 - Feb 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,756 reviews)
Friendly staff, clean room, comfortable bed, husband enjoyed the breakfast.

Reviewed on Feb 17, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy Alcoa TN
$128 nightly
The price is $146 total per night from Feb 22 to Feb 23
$146 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,006 reviews)
Room was spotless and the staff was awesome

Reviewed on Feb 18, 2026

Hilton Knoxville Airport
Comfort Suites Knoxville Airport

Comfort Suites Knoxville Airport

2.5 out of 5
140 Cusick Rd Alcoa TN
$72 nightly
The price is $86 total per night from Feb 24 to Feb 25
$86 total
Feb 24 - Feb 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (767 reviews)
Airport shuttle was late causing us to almost miss our flight. Had to beg to skip the line to make it.

Reviewed on Feb 15, 2026

Comfort Suites Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Knoxville

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$85 nightly
The price is $100 total per night from Feb 21 to Feb 22
$100 total
Feb 21 - Feb 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,756 reviews)
Friendly staff, clean room, comfortable bed, husband enjoyed the breakfast.

Reviewed on Feb 17, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy Alcoa TN
$128 nightly
The price is $146 total per night from Feb 22 to Feb 23
$146 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,006 reviews)
Room was spotless and the staff was awesome

Reviewed on Feb 18, 2026

Hilton Knoxville Airport
Mainstay Suites Knoxville Airport

Mainstay Suites Knoxville Airport

2.5 out of 5
361 Fountain View Cir Alcoa TN
$76 nightly
The price is $90 total per night from Feb 19 to Feb 20
$90 total
Feb 19 - Feb 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (701 reviews)
Clean room nice amenities. Full-size refrigerator comfortable bed.

Reviewed on Feb 17, 2026

Mainstay Suites Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Knoxville Hotels With Airport Transportation

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$85 nightly
The price is $100 total per night from Feb 21 to Feb 22
$100 total
Feb 21 - Feb 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,756 reviews)
Friendly staff, clean room, comfortable bed, husband enjoyed the breakfast.

Reviewed on Feb 17, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962 Alcoa TN
$56 nightly
The price is $66 total per night from Feb 27 to Feb 28
$66 total
Feb 27 - Feb 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Won’t be back

Reviewed on Oct 12, 2025

USA Inn
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$66 nightly
The price is $78 total per night from Feb 26 to Feb 27
$78 total
Feb 26 - Feb 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,002 reviews)
Room was clean but found it to be very noisy on the first floor

Reviewed on Feb 15, 2026

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Knoxville Hotels

USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962 Alcoa TN
$56 nightly
The price is $66 total per night from Feb 27 to Feb 28
$66 total
Feb 27 - Feb 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Won’t be back

Reviewed on Oct 12, 2025

USA Inn
Candlewood Suites Knoxville Airport-Alcoa by IHG

Candlewood Suites Knoxville Airport-Alcoa by IHG

2.5 out of 5
176 Cusick Road Alcoa TN
$63 nightly
The price is $75 total per night from Feb 22 to Feb 23
$75 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, an outdoor pool, and a free airport shuttle. Popular attractions Meigs Falls and Palace ...
8.4/10 Very Good! (621 reviews)
The only, and I do mean only, thing remotely okay about this place is it's close to the airport. That is realistically the nicest thing that can be said for my stay there. I will NEVER stay there again!!

Reviewed on Feb 14, 2026

Candlewood Suites Knoxville Airport-Alcoa by IHG
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$66 nightly
The price is $78 total per night from Feb 26 to Feb 27
$78 total
Feb 26 - Feb 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,002 reviews)
Room was clean but found it to be very noisy on the first floor

Reviewed on Feb 15, 2026

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Knoxville

Comfort Suites Knoxville Airport

Comfort Suites Knoxville Airport

2.5 out of 5
140 Cusick Rd Alcoa TN
$72 nightly
The price is $86 total per night from Feb 24 to Feb 25
$86 total
Feb 24 - Feb 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (767 reviews)
Airport shuttle was late causing us to almost miss our flight. Had to beg to skip the line to make it.

Reviewed on Feb 15, 2026

Comfort Suites Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$66 nightly
The price is $78 total per night from Feb 26 to Feb 27
$78 total
Feb 26 - Feb 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,002 reviews)
Room was clean but found it to be very noisy on the first floor

Reviewed on Feb 15, 2026

Best Western Knoxville Airport/Alcoa
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$85 nightly
The price is $100 total per night from Feb 21 to Feb 22
$100 total
Feb 21 - Feb 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,756 reviews)
Friendly staff, clean room, comfortable bed, husband enjoyed the breakfast.

Reviewed on Feb 17, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

ORD to TYS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
ORD Address & GPS
Address:
10000 West O'Hare
Chicago IL, 60666
United States
IATA Code:
ORD
Longitude:
-87.904876
Latitude:
41.976912
Time Zone:
America/Chicago
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from ORD to TYS?
With multiple carriers providing nonstop flights from ORD to Knoxville Airport, you won't need to worry about switching planes or whiling away the hours on a stopover. For a stress-free, comfortable journey, we recommend traveling with United Airlines or American Airlines.
What is the shortest flight from O'Hare Airport to Knoxville Airport?
Few things are better than an impulsive getaway. And with the flight time from Chicago to Knoxville being just 1 hour and 36 minutes, there's no excuse not to take one.
How many hours flight from ORD to TYS?
It takes a mere 1 hour and 44 minutes on average to travel from O'Hare Intl. Airport (ORD) to TYS. Pull out your guide book and start circling the highlights you'd like to visit. It won't be long before you'll be seeing them in person.
What airlines have the most flights from O'Hare Airport to Knoxville Airport?
What do you factor in when deciding which airline to fly with — great service? Fares that are easy on your bank balance? There are quite a few carriers with flights between O'Hare Airport and TYS to choose from. Have a look at American Airlines (AA), one of the more well-known options which advertises 134 flights each month. If you want to broaden your options, check out the ticket prices from United Airlines (UA), which operates 106 flights from Chicago to Knoxville each month.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore