Cheap flights from TPA to TYS (Tampa Intl. to McGhee Tyson)

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Cheap Flights from TPA to TYS starting at $107 One Way, $201 Round Trip

Prices starting at $201 for return flights and $107 for one-way flights to McGhee Tyson were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near McGhee Tyson

Airport Hotels near McGhee Tyson

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$76 nightly
The price is $90 total per night from Apr 5 to Apr 6
$90 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,814 reviews)
My room was moved to a "pet friendly room". I was ok with that until I went in the room. Pet friendly rooms should have a bordered platform under the box spring so cats cannot get under there. The material under the boxsprings were torn and half of it laid on the floor. Looked very tacky. Before ...

Reviewed on Mar 30, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy Alcoa TN
$132 nightly
The price is $151 total per night from Apr 5 to Apr 6
$151 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,004 reviews)
Perfect location to walk to the airport. Had covered walkway to get to the airport. Would definitely stay here again.Clean, convenient, and friendly staff.

Reviewed on Mar 25, 2026

Hilton Knoxville Airport
Tru by Hilton Alcoa Knoxville Airport

Tru by Hilton Alcoa Knoxville Airport

2.5 out of 5
125 FURROW WAY Alcoa TN
$92 nightly
The price is $109 total per night from Apr 5 to Apr 6
$109 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (691 reviews)
Room were small but fine for the price. Breakfast was good. My only concern was that it appeared that the owners extended family might be living there and there were constantly a lot of kids in the lobby running around and not being controlled.

Reviewed on Mar 23, 2026

Tru by Hilton Alcoa Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Knoxville

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$76 nightly
The price is $90 total per night from Apr 5 to Apr 6
$90 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,814 reviews)
My room was moved to a "pet friendly room". I was ok with that until I went in the room. Pet friendly rooms should have a bordered platform under the box spring so cats cannot get under there. The material under the boxsprings were torn and half of it laid on the floor. Looked very tacky. Before ...

Reviewed on Mar 30, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy Alcoa TN
$132 nightly
The price is $151 total per night from Apr 5 to Apr 6
$151 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,004 reviews)
Perfect location to walk to the airport. Had covered walkway to get to the airport. Would definitely stay here again.Clean, convenient, and friendly staff.

Reviewed on Mar 25, 2026

Hilton Knoxville Airport
Holiday Inn Express & Suites Alcoa (Knoxville Airport) by IHG

Holiday Inn Express & Suites Alcoa (Knoxville Airport) by IHG

2.5 out of 5
130 Associates Blvd Alcoa TN
$110 nightly
The price is $131 total per night from Apr 5 to Apr 6
$131 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (788 reviews)
Hotels.com listed this property as having shuttle service to the airport which it did not. Shame on them for not having up to date records. Ended up having to use Uber which we had not planned on. Hotel is very nice, will not use Hotels.com again

Reviewed on Mar 29, 2026

Holiday Inn Express & Suites Alcoa (Knoxville Airport) by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Knoxville Hotels With Airport Transportation

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$76 nightly
The price is $90 total per night from Apr 5 to Apr 6
$90 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,814 reviews)
My room was moved to a "pet friendly room". I was ok with that until I went in the room. Pet friendly rooms should have a bordered platform under the box spring so cats cannot get under there. The material under the boxsprings were torn and half of it laid on the floor. Looked very tacky. Before ...

Reviewed on Mar 30, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962 Alcoa TN
$53 nightly
The price is $63 total per night from Apr 2 to Apr 3
$63 total
Apr 2 - Apr 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Won’t be back

Reviewed on Oct 12, 2025

USA Inn
Candlewood Suites Knoxville Airport-Alcoa by IHG

Candlewood Suites Knoxville Airport-Alcoa by IHG

2.5 out of 5
176 Cusick Road Alcoa TN
$71 nightly
The price is $84 total per night from Apr 8 to Apr 9
$84 total
Apr 8 - Apr 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, an outdoor pool, and a free airport shuttle. Popular attractions Meigs Falls and Palace ...
8.4/10 Very Good! (633 reviews)
Hotel has a good location, but, unfortunately, the reviews online are a bit inaccurate given our experience. The hotel was very dirty-including the elevator- and needed sweeping and vacuuming. In addition, there was a horrible smell and the bathroom was not clean as well. I hate to leave a review ...

Reviewed on Mar 29, 2026

Candlewood Suites Knoxville Airport-Alcoa by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Knoxville Hotels

USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962 Alcoa TN
$53 nightly
The price is $63 total per night from Apr 2 to Apr 3
$63 total
Apr 2 - Apr 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Won’t be back

Reviewed on Oct 12, 2025

USA Inn
Candlewood Suites Knoxville Airport-Alcoa by IHG

Candlewood Suites Knoxville Airport-Alcoa by IHG

2.5 out of 5
176 Cusick Road Alcoa TN
$71 nightly
The price is $84 total per night from Apr 8 to Apr 9
$84 total
Apr 8 - Apr 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, an outdoor pool, and a free airport shuttle. Popular attractions Meigs Falls and Palace ...
8.4/10 Very Good! (633 reviews)
Hotel has a good location, but, unfortunately, the reviews online are a bit inaccurate given our experience. The hotel was very dirty-including the elevator- and needed sweeping and vacuuming. In addition, there was a horrible smell and the bathroom was not clean as well. I hate to leave a review ...

Reviewed on Mar 29, 2026

Candlewood Suites Knoxville Airport-Alcoa by IHG
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$76 nightly
The price is $90 total per night from Apr 5 to Apr 6
$90 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,814 reviews)
My room was moved to a "pet friendly room". I was ok with that until I went in the room. Pet friendly rooms should have a bordered platform under the box spring so cats cannot get under there. The material under the boxsprings were torn and half of it laid on the floor. Looked very tacky. Before ...

Reviewed on Mar 30, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Knoxville

Comfort Suites Knoxville Airport

Comfort Suites Knoxville Airport

2.5 out of 5
140 Cusick Rd Alcoa TN
$77 nightly
The price is $91 total per night from Apr 19 to Apr 20
$91 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (778 reviews)
Hotel needs some updates, but it’s a decent price and located very close to the airport.

Reviewed on Mar 29, 2026

Comfort Suites Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$76 nightly
The price is $90 total per night from Apr 5 to Apr 6
$90 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,814 reviews)
My room was moved to a "pet friendly room". I was ok with that until I went in the room. Pet friendly rooms should have a bordered platform under the box spring so cats cannot get under there. The material under the boxsprings were torn and half of it laid on the floor. Looked very tacky. Before ...

Reviewed on Mar 30, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Holiday Inn Express & Suites Alcoa (Knoxville Airport) by IHG

Holiday Inn Express & Suites Alcoa (Knoxville Airport) by IHG

2.5 out of 5
130 Associates Blvd Alcoa TN
$110 nightly
The price is $131 total per night from Apr 5 to Apr 6
$131 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (788 reviews)
Hotels.com listed this property as having shuttle service to the airport which it did not. Shame on them for not having up to date records. Ended up having to use Uber which we had not planned on. Hotel is very nice, will not use Hotels.com again

Reviewed on Mar 29, 2026

Holiday Inn Express & Suites Alcoa (Knoxville Airport) by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TPA to TYS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TPA Address & GPS
Address:
5507 West Spruce Street
Tampa FL, 33607
United States
IATA Code:
TPA
Longitude:
-82.535415
Latitude:
27.979869
Time Zone:
America/New_York
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from TPA to Knoxville Airport?
Unfortunately, you won't find any direct flights between these destinations. But American Airlines, Delta Air Lines and United Airlines can get you from TPA to McGhee Tyson Airport (TYS) with just one stopover.
What is the shortest flight from TPA to Knoxville Airport?
From Tampa, the thrilling sights and sounds of Knoxville are around 4 hours and 39 minutes away. Lock in your favorite seat, or maybe even upgrade to one with a bit more legroom, and fly to your destination in pure comfort.
How many hours flight from Tampa Intl. Airport (TPA) to Knoxville Airport?
From TPA to Knoxville Airport, you'll be cruising the skies for roughly 4 hours and 45 minutes. Settle in, order a glass of wine and put on your noise-canceling headphones. It's time to rewatch your favorite TV shows.
What airlines have the most flights from Tampa Intl. Airport (TPA) to Knoxville Airport?
If you want to book with an airline that advertises direct flights from TPA to McGhee Tyson Airport (TYS), you won't have much luck. You'll have to book a flight with at least one stopover to get to your destination.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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