Cheap flights from TPA to TYS (Tampa Intl. to McGhee Tyson)

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Cheap Flights from TPA to TYS starting at $101 One Way, $180 Round Trip

Prices starting at $180 for return flights and $101 for one-way flights to McGhee Tyson were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near McGhee Tyson

Airport Hotels near McGhee Tyson

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road, Alcoa, TN
The price is $85 total per night from Dec 7 to Dec 8
$85 total
per night
Dec 7 - Dec 8
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,637 reviews)
Staff was very nice during our stay, beds were clean, the shower had great water pressure and got really hot. The breakfast was good and had several options, honestly one of the nicest hotel/motel we stayed in besides a Hampton. And that’s only the aesthetics would definitely stay here again if in ...

Reviewed on Nov 1, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
The price is $133 total per night from Dec 7 to Dec 8
$133 total
per night
Dec 7 - Dec 8
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,044 reviews)
Great access everything was easy and affordable

Reviewed on Oct 31, 2025

Hilton Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $82 total per night from Dec 7 to Dec 8
$82 total
per night
Dec 7 - Dec 8
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,035 reviews)
It was very short stay. Arrived after midnight,left there early in am. Staffs were very kind and helpful ,clean room. Only one thing:Have to wait longer time for transportation.

Reviewed on Nov 3, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Knoxville

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road, Alcoa, TN
The price is $85 total per night from Dec 1 to Dec 2
$85 total
per night
Dec 1 - Dec 2
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,637 reviews)
Staff was very nice during our stay, beds were clean, the shower had great water pressure and got really hot. The breakfast was good and had several options, honestly one of the nicest hotel/motel we stayed in besides a Hampton. And that’s only the aesthetics would definitely stay here again if in ...

Reviewed on Nov 1, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
The price is $133 total per night from Dec 7 to Dec 8
$133 total
per night
Dec 7 - Dec 8
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,044 reviews)
Great access everything was easy and affordable

Reviewed on Oct 31, 2025

Hilton Knoxville Airport
Mainstay Suites Knoxville Airport

Mainstay Suites Knoxville Airport

2.5 out of 5
361 Fountain View Cir, Alcoa, TN
The price is $95 total per night from Nov 9 to Nov 10
$95 total
per night
Nov 9 - Nov 10
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
7.6/10 Good! (666 reviews)
Friendly staff

Reviewed on Nov 1, 2025

Mainstay Suites Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Knoxville Hotels With Airport Transportation

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road, Alcoa, TN
The price is $85 total per night from Dec 7 to Dec 8
$85 total
per night
Dec 7 - Dec 8
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,637 reviews)
Staff was very nice during our stay, beds were clean, the shower had great water pressure and got really hot. The breakfast was good and had several options, honestly one of the nicest hotel/motel we stayed in besides a Hampton. And that’s only the aesthetics would definitely stay here again if in ...

Reviewed on Nov 1, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962, Alcoa, TN
The price is $82 total per night from Nov 8 to Nov 9
$82 total
per night
Nov 8 - Nov 9
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Many. Bugs. Full size mattresses on cots. We need a room we missed a flight. We needed some space to sleep, we got it. Minus the sleep.

Reviewed on Sep 16, 2025

USA Inn
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $82 total per night from Dec 7 to Dec 8
$82 total
per night
Dec 7 - Dec 8
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,035 reviews)
It was very short stay. Arrived after midnight,left there early in am. Staffs were very kind and helpful ,clean room. Only one thing:Have to wait longer time for transportation.

Reviewed on Nov 3, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Knoxville Hotels

USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962, Alcoa, TN
The price is $82 total per night from Nov 8 to Nov 9
$82 total
per night
Nov 8 - Nov 9
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Many. Bugs. Full size mattresses on cots. We need a room we missed a flight. We needed some space to sleep, we got it. Minus the sleep.

Reviewed on Sep 16, 2025

USA Inn
Candlewood Suites Knoxville Airport-Alcoa by IHG

Candlewood Suites Knoxville Airport-Alcoa by IHG

2.5 out of 5
176 Cusick Road, Alcoa, TN
The price is $90 total per night from Nov 25 to Nov 26
$90 total
per night
Nov 25 - Nov 26
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Meigs Falls and Palace Theater ...
8.4/10 Very Good! (602 reviews)
Nice place to stay.

Reviewed on Nov 4, 2025

Candlewood Suites Knoxville Airport-Alcoa by IHG
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $82 total per night from Dec 7 to Dec 8
$82 total
per night
Dec 7 - Dec 8
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,035 reviews)
It was very short stay. Arrived after midnight,left there early in am. Staffs were very kind and helpful ,clean room. Only one thing:Have to wait longer time for transportation.

Reviewed on Nov 3, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Knoxville

Comfort Suites Knoxville Airport

Comfort Suites Knoxville Airport

2.5 out of 5
140 Cusick Rd, Alcoa, TN
The price is $90 total per night from Dec 1 to Dec 2
$90 total
per night
Dec 1 - Dec 2
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (736 reviews)
Ok

Reviewed on Nov 1, 2025

Comfort Suites Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $82 total per night from Dec 7 to Dec 8
$82 total
per night
Dec 7 - Dec 8
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,035 reviews)
It was very short stay. Arrived after midnight,left there early in am. Staffs were very kind and helpful ,clean room. Only one thing:Have to wait longer time for transportation.

Reviewed on Nov 3, 2025

Best Western Knoxville Airport/Alcoa
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road, Alcoa, TN
The price is $85 total per night from Dec 1 to Dec 2
$85 total
per night
Dec 1 - Dec 2
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,637 reviews)
Staff was very nice during our stay, beds were clean, the shower had great water pressure and got really hot. The breakfast was good and had several options, honestly one of the nicest hotel/motel we stayed in besides a Hampton. And that’s only the aesthetics would definitely stay here again if in ...

Reviewed on Nov 1, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TPA to TYS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TPA Address & GPS
Address:
5507 West Spruce Street
Tampa FL, 33607
United States
IATA Code:
TPA
Longitude:
-82.535415
Latitude:
27.979869
Time Zone:
America/New_York
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from TPA to Knoxville Airport?
Unfortunately, you won't find any direct flights between these destinations. But American Airlines, Delta Air Lines and United Airlines can get you from TPA to McGhee Tyson Airport (TYS) with just one stopover.
What is the shortest flight from TPA to Knoxville Airport?
From Tampa, the thrilling sights and sounds of Knoxville are around 4 hours and 39 minutes away. Lock in your favorite seat, or maybe even upgrade to one with a bit more legroom, and fly to your destination in pure comfort.
How many hours flight from Tampa Intl. Airport (TPA) to Knoxville Airport?
From TPA to Knoxville Airport, you'll be cruising the skies for roughly 4 hours and 45 minutes. Settle in, order a glass of wine and put on your noise-canceling headphones. It's time to rewatch your favorite TV shows.
What airlines have the most flights from Tampa Intl. Airport (TPA) to Knoxville Airport?
If you want to book with an airline that advertises direct flights from TPA to McGhee Tyson Airport (TYS), you won't have much luck. You'll have to book a flight with at least one stopover to get to your destination.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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