Cheap flights from MCO to TYS (Orlando Intl. to McGhee Tyson)

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Cheap Flights from MCO to TYS starting at $74 One Way, $186 Round Trip

Prices starting at $186 for return flights and $74 for one-way flights to McGhee Tyson were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, May 3 - Fri, May 8
MCO
Orlando
TYS
Knoxville
$186 Roundtrip, found 4 days ago
$186
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sun, May 3 from Orlando to Knoxville, returning Fri, May 8, priced at $186 found 4 days ago
Tue, Apr 28 - Tue, May 5
MCO
Orlando
TYS
Knoxville
$203 Roundtrip, found 4 days ago
$203
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Tue, Apr 28 from Orlando to Knoxville, returning Tue, May 5, priced at $203 found 4 days ago
Tue, Jun 9 - Wed, Jun 10
MCO
Orlando
TYS
Knoxville
$205 Roundtrip, found 2 days ago
$205
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Tue, Jun 9 from Orlando to Knoxville, returning Wed, Jun 10, priced at $205 found 2 days ago
Wed, Apr 22 - Thu, May 7
MCO
Orlando
TYS
Knoxville
$209 Roundtrip, found 3 days ago
$209
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Wed, Apr 22 from Orlando to Knoxville, returning Thu, May 7, priced at $209 found 3 days ago
Sun, May 3 - Fri, May 8
MCO
Orlando
TYS
Knoxville
$211 Roundtrip, found 4 days ago
$211
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sun, May 3 from Orlando to Knoxville, returning Fri, May 8, priced at $211 found 4 days ago

Hotel Ideas near McGhee Tyson

Airport Hotels near McGhee Tyson

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$76 nightly
The price is $90 total per night from Apr 7 to Apr 8
$90 total
Apr 7 - Apr 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,814 reviews)
When we arrived at the hotel they informed us the elevator was broken and only had available rooms on the second and third floor. We took the second floor since we had our children with us and when we arrived to the room is was dirty and smelled like sewage so then we had to be moved to the third ...

Reviewed on Apr 4, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy Alcoa TN
$133 nightly
The price is $152 total per night from Apr 12 to Apr 13
$152 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,003 reviews)
Perfect location to walk to the airport. Had covered walkway to get to the airport. Would definitely stay here again.Clean, convenient, and friendly staff.

Reviewed on Mar 25, 2026

Hilton Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$69 nightly
The price is $82 total per night from Apr 12 to Apr 13
$82 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,004 reviews)
Parking easy, clean room. Found 3 rd floor quieter than 2 nd. Bed was also more comfortable. Shuttle service is very reliable.

Reviewed on Apr 1, 2026

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Knoxville

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$76 nightly
The price is $90 total per night from Apr 7 to Apr 8
$90 total
Apr 7 - Apr 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,814 reviews)
When we arrived at the hotel they informed us the elevator was broken and only had available rooms on the second and third floor. We took the second floor since we had our children with us and when we arrived to the room is was dirty and smelled like sewage so then we had to be moved to the third ...

Reviewed on Apr 4, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy Alcoa TN
$133 nightly
The price is $152 total per night from Apr 12 to Apr 13
$152 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,003 reviews)
Perfect location to walk to the airport. Had covered walkway to get to the airport. Would definitely stay here again.Clean, convenient, and friendly staff.

Reviewed on Mar 25, 2026

Hilton Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$69 nightly
The price is $82 total per night from Apr 12 to Apr 13
$82 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,004 reviews)
Parking easy, clean room. Found 3 rd floor quieter than 2 nd. Bed was also more comfortable. Shuttle service is very reliable.

Reviewed on Apr 1, 2026

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Knoxville Hotels With Airport Transportation

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$76 nightly
The price is $90 total per night from Apr 7 to Apr 8
$90 total
Apr 7 - Apr 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,814 reviews)
When we arrived at the hotel they informed us the elevator was broken and only had available rooms on the second and third floor. We took the second floor since we had our children with us and when we arrived to the room is was dirty and smelled like sewage so then we had to be moved to the third ...

Reviewed on Apr 4, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962 Alcoa TN
$53 nightly
The price is $62 total per night from Apr 10 to Apr 11
$62 total
Apr 10 - Apr 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Won’t be back

Reviewed on Oct 12, 2025

USA Inn
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$69 nightly
The price is $82 total per night from Apr 12 to Apr 13
$82 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,004 reviews)
Parking easy, clean room. Found 3 rd floor quieter than 2 nd. Bed was also more comfortable. Shuttle service is very reliable.

Reviewed on Apr 1, 2026

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Knoxville Hotels

USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962 Alcoa TN
$53 nightly
The price is $62 total per night from Apr 10 to Apr 11
$62 total
Apr 10 - Apr 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Won’t be back

Reviewed on Oct 12, 2025

USA Inn
Candlewood Suites Knoxville Airport-Alcoa by IHG

Candlewood Suites Knoxville Airport-Alcoa by IHG

2.5 out of 5
176 Cusick Road Alcoa TN
$71 nightly
The price is $84 total per night from Apr 19 to Apr 20
$84 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, an outdoor pool, and a free airport shuttle. Popular attractions Meigs Falls and Palace ...
8.4/10 Very Good! (635 reviews)
Probably one of the best hotels I have ever stayed at. Incredibly friendly staff, great outdoor space for dogs, rooms are large and the beds are actually comfortable!! We travel somewhat frequently and will be back.

Reviewed on Mar 31, 2026

Candlewood Suites Knoxville Airport-Alcoa by IHG
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$69 nightly
The price is $82 total per night from Apr 12 to Apr 13
$82 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,004 reviews)
Parking easy, clean room. Found 3 rd floor quieter than 2 nd. Bed was also more comfortable. Shuttle service is very reliable.

Reviewed on Apr 1, 2026

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Knoxville

Comfort Suites Knoxville Airport

Comfort Suites Knoxville Airport

2.5 out of 5
140 Cusick Rd Alcoa TN
$75 nightly
The price is $89 total per night from Apr 12 to Apr 13
$89 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (779 reviews)
Hotel needs some updates, but it’s a decent price and located very close to the airport.

Reviewed on Mar 29, 2026

Comfort Suites Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$69 nightly
The price is $82 total per night from Apr 12 to Apr 13
$82 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,004 reviews)
Parking easy, clean room. Found 3 rd floor quieter than 2 nd. Bed was also more comfortable. Shuttle service is very reliable.

Reviewed on Apr 1, 2026

Best Western Knoxville Airport/Alcoa
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$76 nightly
The price is $90 total per night from Apr 7 to Apr 8
$90 total
Apr 7 - Apr 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,814 reviews)
When we arrived at the hotel they informed us the elevator was broken and only had available rooms on the second and third floor. We took the second floor since we had our children with us and when we arrived to the room is was dirty and smelled like sewage so then we had to be moved to the third ...

Reviewed on Apr 4, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MCO to TYS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MCO Address & GPS
Address:
One Airport Boulevard
Orlando FL, 32827-4399
United States
IATA Code:
MCO
Longitude:
-81.308301
Latitude:
28.432177
Time Zone:
America/New_York
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from MCO to McGhee Tyson Airport (TYS)?
If you're thinking of flying from Orlando Intl. Airport (MCO) to TYS, you'll have to change planes. American Airlines, Delta Air Lines and United Airlines are airlines that operate on this route with just one stopover. Use the time to stretch those legs and get something to eat.
What is the shortest flight from Orlando Intl. Airport to Knoxville Airport?
Grab the opportunity to sit back and chill out on your way from Orlando to Knoxville. The shortest flight time from Orlando Intl. Airport to TYS is 4 hours and 40 minutes, which gives you loads of time to indulge in a tipple or get carried away with a good book.
How many hours flight from Orlando Intl. Airport to Knoxville Airport?
From MCO to TYS, you'll be in your seat for approximately 4 hours and 47 minutes. Settle in, order a glass of bubbly and take out your noise-canceling headphones. It's time to binge-watch your favorite TV shows.
What airlines have the most flights from Orlando Intl. Airport to Knoxville Airport?
If you want to find an airline that flies direct from Orlando Intl. Airport to Knoxville Airport, you're out of luck. You'll need to book a flight with at least one stopover to get to Knoxville.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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