Cheap flights from MCO to TYS (Orlando Intl. to McGhee Tyson)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from MCO to TYS starting at $87 One Way, $174 Round Trip

Prices starting at $174 for return flights and $87 for one-way flights to McGhee Tyson were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Feb 26 - Mon, Mar 2
MCO
Orlando
TYS
Knoxville
$174 Roundtrip, found 6 days ago
$174
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Feb 26 from Orlando to Knoxville, returning Mon, Mar 2, priced at $174 found 6 days ago
Thu, May 7 - Sun, May 10
MCO
Orlando
TYS
Knoxville
$181 Roundtrip, found 3 days ago
$181
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Thu, May 7 from Orlando to Knoxville, returning Sun, May 10, priced at $181 found 3 days ago
Wed, Apr 29 - Thu, Apr 30
MCO
Orlando
TYS
Knoxville
$185 Roundtrip, found 5 days ago
$185
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Wed, Apr 29 from Orlando to Knoxville, returning Thu, Apr 30, priced at $185 found 5 days ago
Sun, Apr 19 - Wed, Apr 22
MCO
Orlando
TYS
Knoxville
$191 Roundtrip, found 5 days ago
$191
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sun, Apr 19 from Orlando to Knoxville, returning Wed, Apr 22, priced at $191 found 5 days ago
Thu, Apr 16 - Tue, Apr 21
MCO
Orlando
TYS
Knoxville
$194 Roundtrip, found 3 days ago
$194
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Thu, Apr 16 from Orlando to Knoxville, returning Tue, Apr 21, priced at $194 found 3 days ago

Hotel Ideas near McGhee Tyson

Airport Hotels near McGhee Tyson

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$85 nightly
The price is $100 total per night from Feb 21 to Feb 22
$100 total
Feb 21 - Feb 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,759 reviews)
Friendly staff, clean room, comfortable bed, husband enjoyed the breakfast.

Reviewed on Feb 17, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy Alcoa TN
$128 nightly
The price is $146 total per night from Feb 22 to Feb 23
$146 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,006 reviews)
Room was spotless and the staff was awesome

Reviewed on Feb 18, 2026

Hilton Knoxville Airport
Comfort Suites Knoxville Airport

Comfort Suites Knoxville Airport

2.5 out of 5
140 Cusick Rd Alcoa TN
$72 nightly
The price is $86 total per night from Feb 24 to Feb 25
$86 total
Feb 24 - Feb 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (766 reviews)
Airport shuttle was late causing us to almost miss our flight. Had to beg to skip the line to make it.

Reviewed on Feb 15, 2026

Comfort Suites Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Knoxville

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$85 nightly
The price is $100 total per night from Feb 21 to Feb 22
$100 total
Feb 21 - Feb 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,759 reviews)
Friendly staff, clean room, comfortable bed, husband enjoyed the breakfast.

Reviewed on Feb 17, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy Alcoa TN
$128 nightly
The price is $146 total per night from Feb 22 to Feb 23
$146 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,006 reviews)
Room was spotless and the staff was awesome

Reviewed on Feb 18, 2026

Hilton Knoxville Airport
Mainstay Suites Knoxville Airport

Mainstay Suites Knoxville Airport

2.5 out of 5
361 Fountain View Cir Alcoa TN
$76 nightly
The price is $90 total per night from Feb 19 to Feb 20
$90 total
Feb 19 - Feb 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (701 reviews)
Clean room nice amenities. Full-size refrigerator comfortable bed.

Reviewed on Feb 17, 2026

Mainstay Suites Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Knoxville Hotels With Airport Transportation

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$85 nightly
The price is $100 total per night from Feb 21 to Feb 22
$100 total
Feb 21 - Feb 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,759 reviews)
Friendly staff, clean room, comfortable bed, husband enjoyed the breakfast.

Reviewed on Feb 17, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962 Alcoa TN
$76 nightly
The price is $90 total per night from Feb 25 to Feb 26
$90 total
Feb 25 - Feb 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Won’t be back

Reviewed on Oct 12, 2025

USA Inn
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$66 nightly
The price is $79 total per night from Feb 27 to Feb 28
$79 total
Feb 27 - Feb 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,002 reviews)
Room was clean but found it to be very noisy on the first floor

Reviewed on Feb 15, 2026

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Knoxville Hotels

USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962 Alcoa TN
$76 nightly
The price is $90 total per night from Feb 25 to Feb 26
$90 total
Feb 25 - Feb 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Won’t be back

Reviewed on Oct 12, 2025

USA Inn
Candlewood Suites Knoxville Airport-Alcoa by IHG

Candlewood Suites Knoxville Airport-Alcoa by IHG

2.5 out of 5
176 Cusick Road Alcoa TN
$63 nightly
The price is $75 total per night from Feb 22 to Feb 23
$75 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, an outdoor pool, and a free airport shuttle. Popular attractions Meigs Falls and Palace ...
8.4/10 Very Good! (621 reviews)
The only, and I do mean only, thing remotely okay about this place is it's close to the airport. That is realistically the nicest thing that can be said for my stay there. I will NEVER stay there again!!

Reviewed on Feb 14, 2026

Candlewood Suites Knoxville Airport-Alcoa by IHG
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$66 nightly
The price is $79 total per night from Feb 27 to Feb 28
$79 total
Feb 27 - Feb 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,002 reviews)
Room was clean but found it to be very noisy on the first floor

Reviewed on Feb 15, 2026

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Knoxville

Comfort Suites Knoxville Airport

Comfort Suites Knoxville Airport

2.5 out of 5
140 Cusick Rd Alcoa TN
$72 nightly
The price is $86 total per night from Feb 24 to Feb 25
$86 total
Feb 24 - Feb 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (766 reviews)
Airport shuttle was late causing us to almost miss our flight. Had to beg to skip the line to make it.

Reviewed on Feb 15, 2026

Comfort Suites Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd Alcoa TN
$66 nightly
The price is $79 total per night from Feb 27 to Feb 28
$79 total
Feb 27 - Feb 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,002 reviews)
Room was clean but found it to be very noisy on the first floor

Reviewed on Feb 15, 2026

Best Western Knoxville Airport/Alcoa
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
$85 nightly
The price is $100 total per night from Feb 21 to Feb 22
$100 total
Feb 21 - Feb 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,759 reviews)
Friendly staff, clean room, comfortable bed, husband enjoyed the breakfast.

Reviewed on Feb 17, 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MCO to TYS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MCO Address & GPS
Address:
One Airport Boulevard
Orlando FL, 32827-4399
United States
IATA Code:
MCO
Longitude:
-81.308301
Latitude:
28.432177
Time Zone:
America/New_York
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from MCO to McGhee Tyson Airport (TYS)?
If you're thinking of flying from Orlando Intl. Airport (MCO) to TYS, you'll have to change planes. American Airlines, Delta Air Lines and United Airlines are airlines that operate on this route with just one stopover. Use the time to stretch those legs and get something to eat.
What is the shortest flight from Orlando Intl. Airport to Knoxville Airport?
Grab the opportunity to sit back and chill out on your way from Orlando to Knoxville. The shortest flight time from Orlando Intl. Airport to TYS is 4 hours and 40 minutes, which gives you loads of time to indulge in a tipple or get carried away with a good book.
How many hours flight from Orlando Intl. Airport to Knoxville Airport?
From MCO to TYS, you'll be in your seat for approximately 4 hours and 47 minutes. Settle in, order a glass of bubbly and take out your noise-canceling headphones. It's time to binge-watch your favorite TV shows.
What airlines have the most flights from Orlando Intl. Airport to Knoxville Airport?
If you want to find an airline that flies direct from Orlando Intl. Airport to Knoxville Airport, you're out of luck. You'll need to book a flight with at least one stopover to get to Knoxville.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore