$88 Cheap flight deals from St. Petersburg - Clearwater (TPA) to Knoxville (TYS)

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This Weekend's Flight Deals from St. Petersburg - Clearwater to Knoxville

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Dec 21 - Thu, Dec 25
TPA
Tampa Intl.
TYS
McGhee Tyson
$392 Roundtrip, found 1 hour ago
$392
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Sun, Dec 21 from Tampa Intl. to McGhee Tyson, returning Thu, Dec 25, priced at $392 found 1 hour ago

Airfares from $88 One Way, $158 Round Trip from St. Petersburg - Clearwater to Knoxville

Prices starting at $158 for return flights and $88 for one-way flights to Knoxville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Feb 8 - Thu, Feb 26
TPA
Tampa
TYS
Knoxville
$158 Roundtrip, found 4 days ago
$158
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sun, Feb 8 from Tampa to Knoxville, returning Thu, Feb 26, priced at $158 found 4 days ago
Sat, Jan 10 - Mon, Jan 26
TPA
Tampa
TYS
Knoxville
$172 Roundtrip, found 1 day ago
$172
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Jan 10 from Tampa to Knoxville, returning Mon, Jan 26, priced at $172 found 1 day ago
Wed, Jan 7 - Mon, Jan 26
TPA
Tampa
TYS
Knoxville
$173 Roundtrip, found 1 day ago
$173
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Jan 7 from Tampa to Knoxville, returning Mon, Jan 26, priced at $173 found 1 day ago
Sat, Feb 14 - Thu, Feb 26
TPA
Tampa
TYS
Knoxville
$193 Roundtrip, found 4 days ago
$193
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sat, Feb 14 from Tampa to Knoxville, returning Thu, Feb 26, priced at $193 found 4 days ago
Wed, Jan 7 - Thu, Jan 15
TPA
Tampa
TYS
Knoxville
$194 Roundtrip, found 3 days ago
$194
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, Jan 7 from Tampa to Knoxville, returning Thu, Jan 15, priced at $194 found 3 days ago

Knoxville economy flight packages

Price found within the past 48 hours. Click for updated prices.
Sunrise Ridge Resort
3.0-star property

Sunrise Ridge Resort

9/10 Wonderful! (1,002 reviews)

Jan 23 - Jan 26

3 night stay

Tampa (TPA) to Knoxville (TYS)

American Airlines • Non-stop roundtrip • Coach
Price was $419, price is now $324 per person
$324
per person
found 2 hours ago
I loved the location.

Reviewed on Dec 30, 2024

Westgate Smoky Mountain Resort & Water Park
4.0-star property

Westgate Smoky Mountain Resort & Water Park

8.4/10 Very Good! (1,122 reviews)

Jan 23 - Jan 26

3 night stay

Tampa (TPA) to Knoxville (TYS)

American Airlines • Non-stop roundtrip • Coach
Price was $590, price is now $405 per person
$405
per person
found 2 hours ago
Absolutely loved our visit, Staff was friendly, accommodation were wonderful, quiet, close to nature.

Reviewed on Jun 20, 2025

The Ramsey Hotel & Convention Center
3.0-star property

The Ramsey Hotel & Convention Center

8.4/10 Very Good! (1,299 reviews)

Jan 23 - Jan 26

3 night stay

Tampa (TPA) to Knoxville (TYS)

American Airlines • Non-stop roundtrip • Coach
Price was $521, price is now $395 per person
$395
per person
found 2 hours ago
Cleanliness average; Some staff members deficient in Southern Hospitality to certain Guests; Shopping average

Reviewed on Oct 5, 2025

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More About Flying To Knoxville from St. Petersburg - Clearwater

Route Information for Flights from St. Petersburg - Clearwater to Knoxville

Origin Airport IATA Code
TPA
Destination Airport IATA Code
TYS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

St. Petersburg - Clearwater to Knoxville

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Booking a trip from St. Petersburg - Clearwater to Knoxville has never been easier. Not only will you find great deals on flights, we offer bargains on cruises, car rentals, top-notch hotels, and more. You can also research and add local activities in Knoxville to your flight or hotel reservation to keep the kids happy and active.

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Frequently asked questions

Are there non-stop flights from St. Petersburg - Clearwater to Knoxville?
Allegiant Air flies direct from St. Pete-Clearwater Intl. Airport to TYS, so you won't have to stress about changing planes or missing your next flight on this route.
What is the shortest flight from St. Petersburg - Clearwater to Knoxville?
Leave that movie marathon for the hotel room, because the flight from Tampa Intl. Airport (TPA) to TYS can be as quick as 2 hours and 14 minutes.
What airlines fly from St. Petersburg - Clearwater to Knoxville most frequently?
If you're after the carrier with the most frequent flights from St. Petersburg, FL (PIE-St. Petersburg-Clearwater Intl.) to Knoxville Airport, buckle up and take off with Allegiant Air. This airline offers 30 flights every month along this route.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.