Cheap Flight Deals From Syracuse (SYR) to Knoxville (TYS) Starting at $84

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This Weekend's Flight Deals from Syracuse to Knoxville

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Oct 1 - Sat, Oct 21
SYR
Hancock Intl.
TYS
McGhee Tyson
$395 Roundtrip, found 4 days ago
$395
Roundtrip
found 4 days ago
Select United flight, departing Sun, Oct 1 from Hancock Intl. to McGhee Tyson, returning Sat, Oct 21, priced at $395 found 4 days ago

Airfares from $84 One Way, $168 Round Trip from Syracuse to Knoxville

Prices starting at $168 for return flights and $84 for one-way flights to Knoxville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Nov 30 - Sat, Dec 16
SYR
Syracuse
TYS
Knoxville
$168 Roundtrip, found 4 days ago
$168
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Nov 30 from Syracuse to Knoxville, returning Sat, Dec 16, priced at $168 found 4 days ago
Sun, Nov 19 - Mon, Dec 4
SYR
Syracuse
TYS
Knoxville
$172 Roundtrip, found 4 days ago
$172
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sun, Nov 19 from Syracuse to Knoxville, returning Mon, Dec 4, priced at $172 found 4 days ago
Thu, Nov 30 - Fri, Dec 15
SYR
Syracuse
TYS
Knoxville
$188 Roundtrip, found 4 days ago
$188
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Nov 30 from Syracuse to Knoxville, returning Fri, Dec 15, priced at $188 found 4 days ago
Thu, Nov 23 - Mon, Dec 4
SYR
Syracuse
TYS
Knoxville
$218 Roundtrip, found 4 days ago
$218
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Nov 23 from Syracuse to Knoxville, returning Mon, Dec 4, priced at $218 found 4 days ago
Thu, Jan 4 - Thu, Jan 11
SYR
Syracuse
TYS
Knoxville
$221 Roundtrip, found 3 days ago
$221
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Jan 4 from Syracuse to Knoxville, returning Thu, Jan 11, priced at $221 found 3 days ago

More About Flying To Knoxville from Syracuse

Route Information for Flights from Syracuse to Knoxville

Origin Airport IATA Code
SYR
Destination Airport IATA Code
TYS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Syracuse to Knoxville

Looking for guaranteed low prices on Syracuse to Knoxville flights? Orbitz is your source and much more. From cutting-edge mobile tools to great deals, Orbitz makes it easy to book your dream vacation.

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Easily Plan Your Vacation

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Frequently asked questions

Am I able to catch a flight from Syracuse to Knoxville now?
Head to the Covid-19 Travel Advisor for the most useful info on quarantine and travel restrictions when catching a flight from Syracuse to Knoxville.
What is the shortest flight from Syracuse to Knoxville?
The trip from Syracuse to Knoxville can be as quick as 2 hours and 50 minutes. With a short and sweet flight time like this, why not grab some friends and organize an impromptu getaway?
If I am not able to travel due to COVID-19, can I cancel my flight to Knoxville?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Knoxville have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Knoxville with flexible change policies?
In most cases you’ll have the option to reschedule your flight to Knoxville without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.