$130 Cheap flight deals from Panama City (PNS) to Knoxville (TYS)

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This Weekend's Flight Deals from Panama City to Knoxville

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, May 24 - Sun, May 25
VPS
Northwest Florida Regional
TYS
McGhee Tyson
$356 Roundtrip, found 1 day ago
$356
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, May 24 from Northwest Florida Regional to McGhee Tyson, returning Sun, May 25, priced at $356 found 1 day ago

Airfares from $130 One Way, $266 Round Trip from Panama City to Knoxville

Prices starting at $266 for return flights and $130 for one-way flights to Knoxville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jul 19 - Thu, Jul 24
PNS
Pensacola
TYS
Knoxville
$266 Roundtrip, found 3 days ago
$266
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sat, Jul 19 from Pensacola to Knoxville, returning Thu, Jul 24, priced at $266 found 3 days ago
Sat, Jun 14 - Thu, Jun 19
PNS
Pensacola
TYS
Knoxville
$283 Roundtrip, found 2 days ago
$283
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sat, Jun 14 from Pensacola to Knoxville, returning Thu, Jun 19, priced at $283 found 2 days ago
Tue, Jun 10 - Tue, Jun 17
ECP
Panama City
TYS
Knoxville
$297 Roundtrip, found 1 day ago
$297
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jun 10 from Panama City to Knoxville, returning Tue, Jun 17, priced at $297 found 1 day ago
Sat, Jun 21 - Thu, Jun 26
PNS
Pensacola
TYS
Knoxville
$315 Roundtrip, found 5 days ago
$315
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sat, Jun 21 from Pensacola to Knoxville, returning Thu, Jun 26, priced at $315 found 5 days ago
Sun, May 25 - Wed, May 28
VPS
Fort Walton Beach
TYS
Knoxville
$317 Roundtrip, found 4 days ago
$317
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sun, May 25 from Fort Walton Beach to Knoxville, returning Wed, May 28, priced at $317 found 4 days ago

More About Flying To Knoxville from Panama City

Route Information for Flights from Panama City to Knoxville

Origin Airport IATA Code
PNS
Destination Airport IATA Code
TYS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Panama City to Knoxville

For the best travel experience from Panama City to Knoxville domestic and international travelers everywhere choose Orbitz for guaranteed low prices and cutting-edge mobile tools.

Convenient Low-Cost Travel

Orbitz makes it simple to book discount flights from Panama City to {destination.name} without compromising your schedule. You can always find deals on domestic flights from a location near you. You may find the best deals to fit your schedule by mixing and matching airlines to get you from Panama City to Knoxville.

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Frequently asked questions

Are there non-stop flights from Panama City to Knoxville?
Allegiant Air will fly you nonstop from Northwest Florida Regional Airport (VPS) to McGhee Tyson Airport (TYS), which means you won’t have to stress about swapping planes or missing your connection on this route.
What is the shortest flight from Panama City to Knoxville?
If conditions are good and there are no delays, you could be stepping off the plane at TYS from Pensacola Airport in only 1 hour and 58 minutes. With such a brief flight time, think about bringing hand luggage only.
What airlines fly from Panama City to Knoxville most frequently?
Allegiant Air is the most frequent flyer along this route. This top-rated carrier operates 8 flights from Destin–Fort Walton Beach Airport to Knoxville Airport every month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.