$139 Cheap flight deals from Panama City (PNS) to Knoxville (TYS)

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Airfares from $139 One Way, $269 Round Trip from Panama City to Knoxville

Prices starting at $269 for return flights and $139 for one-way flights to Knoxville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Sep 29 - Wed, Sep 30
ECP
Panama City
TYS
Knoxville
$269 Roundtrip, found 6 days ago
$269
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Sep 29 from Panama City to Knoxville, returning Wed, Sep 30, priced at $269 found 6 days ago
Tue, Sep 29 - Wed, Sep 30
ECP
Panama City
TYS
Knoxville
$269 Roundtrip, found 6 days ago
$269
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Tue, Sep 29 from Panama City to Knoxville, returning Wed, Sep 30, priced at $269 found 6 days ago
Wed, Sep 23 - Sat, Sep 26
PNS
Pensacola
TYS
Knoxville
$279 Roundtrip, found 3 days ago
$279
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Sep 23 from Pensacola to Knoxville, returning Sat, Sep 26, priced at $279 found 3 days ago
Wed, Sep 23 - Sat, Sep 26
PNS
Pensacola
TYS
Knoxville
$285 Roundtrip, found 3 days ago
$285
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Wed, Sep 23 from Pensacola to Knoxville, returning Sat, Sep 26, priced at $285 found 3 days ago
Thu, Aug 6 - Sat, Aug 15
PNS
Pensacola
TYS
Knoxville
$289 Roundtrip, found 3 days ago
$289
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Thu, Aug 6 from Pensacola to Knoxville, returning Sat, Aug 15, priced at $289 found 3 days ago

More About Flying To Knoxville from Panama City

Route Information for Flights from Panama City to Knoxville

Origin Airport IATA Code
PNS
Destination Airport IATA Code
TYS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Panama City to Knoxville

Great Deals on Flights From Panama City to Knoxville

Spend more of your time and money at Knoxville instead of sitting at your computer, searching for discount Panama City to Knoxville flights. This is why Orbitz makes it easy for you to check out destinations, plan your trip, and book your air fare, hotel, car rental, and more in just one place. Our low price guarantee means that you get great deals on flights from Panama City to Knoxville.

Flights That Fit Your Budget

Traveling on a budget? Not to worry if you are using Orbitz. We monitor thousands of fares to make sure we show you the best air ticket prices available for your travel dates. Besides amazing prices on Panama City to Knoxville flights, we offer you great deals on hotels, vacation packages, and last-minute getaways for the perfect trip.

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Orbitz offers free mobile apps for iPad, iPhone, and Android-based devices, so even the busiest trip-planner can research and book flights from Panama City to Knoxville. Find cheap Panama City to Knoxville flights, research local festivities and attractions, and book reservations while sitting in the salon. Orbitz will also update you on flight delays with free alerts sent to your mobile phone or email address, so you’re never left in the dark.

Frequently asked questions

Are there non-stop flights from Panama City to Knoxville?
Allegiant Air will fly you nonstop from Northwest Florida Regional Airport (VPS) to McGhee Tyson Airport (TYS), which means you won't have to stress about swapping planes or missing your connection on this route.
What is the shortest flight from Panama City to Knoxville?
If conditions are good and there are no delays, you could be stepping off the plane at TYS from Pensacola Airport in only 1 hour and 58 minutes. With such a brief flight time, think about bringing hand luggage only.
What airlines fly from Panama City to Knoxville most frequently?
Allegiant Air is the most frequent flyer along this route. This top-rated carrier operates 8 flights from Destin–Fort Walton Beach Airport to Knoxville Airport every month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.