$122 Cheap flight deals from Panama City (PNS) to Knoxville (TYS)

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This Weekend's Flight Deals from Panama City to Knoxville

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Airfares from $122 One Way, $269 Round Trip from Panama City to Knoxville

Prices starting at $269 for return flights and $122 for one-way flights to Knoxville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Knoxville economy flight packages

Price found within the past 48 hours. Click for updated prices.
Sunrise Ridge Resort
The Resort at Governor's Crossing
Compass Hotel by Margaritaville
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More About Flying To Knoxville from Panama City

Route Information for Flights from Panama City to Knoxville

Origin Airport IATA Code
PNS
Destination Airport IATA Code
TYS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Panama City to Knoxville

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Frequent Flyer Rewards

If you are a member of a frequent flyer program, Orbitz will ensure you get points or miles for your qualifying Panama City to Knoxville flights. Just provide your frequent flyer number or your loyalty program number when booking your flight online with Orbtiz.com.

Flight Deals on the Go

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Guaranteed low prices for Panama City to Knoxville flights makes Orbitz the perfect online budget travel source.

Frequently asked questions

Are there non-stop flights from Panama City to Knoxville?
Allegiant Air will fly you nonstop from Northwest Florida Regional Airport (VPS) to McGhee Tyson Airport (TYS), which means you won’t have to stress about swapping planes or missing your connection on this route.
What is the shortest flight from Panama City to Knoxville?
If conditions are good and there are no delays, you could be stepping off the plane at TYS from Pensacola Airport in only 1 hour and 58 minutes. With such a brief flight time, think about bringing hand luggage only.
What airlines fly from Panama City to Knoxville most frequently?
Allegiant Air is the most frequent flyer along this route. This top-rated carrier operates 8 flights from Destin–Fort Walton Beach Airport to Knoxville Airport every month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.