Hotels in Santa Clara
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Featured Hotels in Santa Clara

Principe Hotel and Suites
Via Argentina Panama City Panama
Free Cancellation
Reserve now, pay when you stay
4.83 mi from Santa Clara
$57 nightly
The price is $62 total per night
$62 total
Jun 24 - Jun 25
Total with taxes and fees
At Principe Hotel and Suites, guests have access to an outdoor pool, free WiFi in public areas, and meeting rooms. There's free parking, and an airport shuttle (available 24 hours) for PAB 30 per vehicle one-way. The 24-hour front desk has staff standing by to help with concierge services, securing valuables, and luggage storage. Additional amenities include a business center, a terrace, and laundry facilities.

Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
Free Cancellation
Reserve now, pay when you stay
4.99 mi from Santa Clara
$128 nightly
The price is $141 total per night
$141 total
Jul 3 - Jul 4
Total with taxes and fees
At Las Americas Golden Tower Panama, guests enjoy a full-service spa, an indoor pool, and a gym. A stay here includes free parking. Front-desk staff can answer questions 24/7, and assist with tours or tickets, dry cleaning/laundry, and securing valuables. Other amenities at this spa hotel include a sauna, free WiFi in public areas, and conference space.

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Free Cancellation
Reserve now, pay when you stay
4.99 mi from Santa Clara
$147 nightly
The price is $162 total per night
$162 total
Jun 29 - Jun 30
Total with taxes and fees
At Hotel Riu Plaza Panama, guests enjoy an outdoor pool, a gym, and free WiFi in public areas. Valet parking is offered for PAB 12 per night. The front desk is staffed 24/7 to help with tours or tickets, securing valuables, and luggage storage. Other amenities at this luxury hotel include meeting rooms, conference space, and a business center.

Megapolis Hotel Panamá
Avenida Balboa Panama City
Free Cancellation
Reserve now, pay when you stay
5.08 mi from Santa Clara
$131 nightly
The price is $145 total per night
$145 total
Jul 19 - Jul 20
Total with taxes and fees
Guests of Megapolis Hotel Panamá have access to a full-service spa, a casino, and an outdoor pool. There's free valet parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage, dry cleaning/laundry, and concierge services. Other amenities at this luxury hotel include a gym, a sauna, and free WiFi in public areas.

The Executive Hotel
Calle 52 Panama City Panama
Free Cancellation
5.22 mi from Santa Clara
$90 nightly
The price is $98 total per night
$98 total
Jul 17 - Jul 18
Total with taxes and fees
Guests of The Executive Hotel have access to an outdoor pool, a gym, and a steam room. There's free parking, and an airport shuttle (available on request) for USD 30 per person one-way. Multilingual staff at the front desk are standing by 24/7 to help with securing valuables, luggage storage, and tours or tickets. Additional amenities include free WiFi in public areas, conference space, and a business center.

W Panama
Calle Aquilino de la Guardia & Calle 50 Panama City
Free Cancellation
Reserve now, pay when you stay
5.23 mi from Santa Clara
$249 nightly
The price is $274 total per night
$274 total
Jun 26 - Jun 27
Total with taxes and fees
Guests staying at W Panama enjoy an outdoor pool, a gym, and 3 hot tubs. The front desk has multilingual staff on hand 24/7 to help with dry cleaning/laundry, luggage storage, and concierge services. Other amenities at this luxury hotel include a rooftop terrace, WiFi in public areas, and conference space.

Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
Free Cancellation
6.31 mi from Santa Clara
$141 nightly
The price is $155 total per night
$155 total
Jul 20 - Jul 21
Total with taxes and fees
Crowne Plaza Panama Airport by IHG features an outdoor pool, a children's pool, and a 24-hour gym. Airport transportation is made easy with a free airport shuttle (available 24 hours). The 24-hour front desk has staff standing by to help with tours or tickets, securing valuables, and dry cleaning/laundry. Other amenities at this family-friendly hotel include free WiFi in public areas, conference space, and a business center.

Central Hotel Panama Casco Viejo
Plaza de la Independencia Casco Viejo Panama City Panama
Free Cancellation
Reserve now, pay when you stay
7.15 mi from Santa Clara
$174 nightly
The price is $192 total per night
$192 total
Jul 15 - Jul 16
Total with taxes and fees
Guests of Central Hotel Panama Casco Viejo enjoy a full-service spa, an outdoor pool, and a 24-hour gym. Valet parking is offered for USD 10.70 per night. The front desk is staffed 24/7 to help with securing valuables, luggage storage, and concierge services. Other amenities at this spa hotel include a steam room, a rooftop terrace, and free WiFi in public areas.

Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
Free Cancellation
Reserve now, pay when you stay
12.08 mi from Santa Clara
$299 nightly
The price is $299 total per night
$299 total
Jun 23 - Jun 24
Total with taxes and fees
Guests of Dreams Playa Bonita Panama - All Inclusive have access to a full-service spa, 4 outdoor pools, and a nightclub. There's free parking, and an airport shuttle (available 24 hours) for USD 25 per person one-way. Multilingual staff at the 24-hour front desk can assist with dry cleaning/laundry, securing valuables, and tours or tickets. Other amenities at this all-inclusive property include karaoke, a children's pool, and a 24-hour gym.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Santa Clara hotels essential information
Accommodation | 1,766 hotels |
|---|---|
Lowest Price | $62 |
Highest Price | $299 |
Popular hotels | Hotel Riu Plaza Panama, Crowne Plaza Panama Airport by IHG, Dreams Playa Bonita Panama - All Inclusive, Principe Hotel and Suites, The Executive Hotel, Las Americas Golden Tower Panama, Megapolis Hotel Panamá, Central Hotel Panama Casco Viejo, W Panama |
Popular places to visit

Cinta Costera
4.5/5(458 reviews)
After visiting Cinta Costera, make a plan to see the other sights and activities in Panama City. While you're in the area, stroll along the seaside.

Multiplaza Pacific Mall
4.5/5(643 reviews)
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Amador Causeway
4.5/5(767 reviews)
You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.
Recent Reviews

Hotel Riu Plaza Panama
5/5 Excellent
"I will loved to go back soon"
A verified traveler stayed at Hotel Riu Plaza Panama
Posted 1 hour ago
More to Explore
- Juan Diaz Hotels
- Hotels near Tocumen Intl.
- Hotels near ATLAPA Conventions Center
- Hotels with Bar in Punta Paitilla
- Punta Paitilla Hotels
- Hotels near Fiesta Casino
- Hotels near Cinta Costera
- Hotels near Albrook Shopping Mall
- Hotels near Atrio Mall
- Obarrio Hotels
- Hotels near Via Espana
- San Miguelito Hotels
- Rio Abajo Hotels
- Costa del Este Hotels
- Casino Resorts & in El Cangrejo
- Cheap Hotels in El Cangrejo
- Hotels with Bar in El Cangrejo
- Pet Friendly Hotels in El Cangrejo
- El Cangrejo Hotels
- Bethania Hotels
- Punta Pacifica Hotels
- Hotels near Multiplaza Pacific Mall
- Hotels near National Theater
- Cerro Viento Hotels
- Parque Lefevre Hotels
- Campo Alegre Hotels
- 5 Star Hotels in Panama City
- All Inclusive Resorts & in Panama City
- Boutique Hotels in Panama City
- Casino Resorts & in Panama City
- Cheap Hotels in Panama City
- Panama City Hotels
- Panamá Province Hotels
- Hotels near El Dorado Mall
- Marbella Hotels
- Hotels with Bar in Bella Vista
- Hotels with Hot Tubs in Bella Vista
- Ski Resorts & in Bella Vista
- Bella Vista Hotels
- Hotels near Crown Casino
- Hotels near Bingo 90
- Las Cumbres Hotels
- San Francisco Hotels
- Flights from San Miguelito
- Flights from Atlanta to Panama City
- Flights from Austin to Panama City
- Flights from Boston to Panama City
- Flights from Chicago to Panama City
- Flights from Columbus to Panama City
- Flights from Dallas to Panama City
- Flights from Denver to Panama City
- Flights from Detroit to Panama City
- Flights from Houston to Panama City
- Flights from Las Vegas to Panama City
- Flights from Los Angeles to Panama City
- Flights from Mexico City to Panama City
- Flights from Miami to Panama City
- Flights from New York to Panama City
- Flights from Orlando to Panama City
- Flights from Phoenix to Panama City
- Flights from Portland to Panama City
- Flights from Raleigh to Panama City
- Flights from San Antonio to Panama City
- Flights from San Francisco to Panama City
- Flights from St. Petersburg - Clearwater to Panama City
- Flights from Toronto to Panama City
- Flights from Vancouver to Panama City
- Flights from Washington to Panama City
- Flights from Cancun to Panama City
- Flights from Kingston to Panama City
- Flights from Montego Bay to Panama City
- Flights from Medellin to Panama City
- Flights from Port of Spain to Panama City
- Flights from San Juan to Panama City
- Flights from David to Panama City
- Flights from Fort Lauderdale to Panama City
- Flights from Newark to Panama City
- Flights from Bocas del Toro to Panama City
- Flights from Fort Myers to Panama City
- Flights from Grand Cayman to Panama City
- Flights from Tampa to Panama City
- Flights from Jacksonville to Panama City
- Flights from San José to Panama City
- Flights from Gainesville to Panama City
- Flights from Quito to Panama City
- Flights from Managua to Panama City
- Flights from San Salvador to Panama City
- Flights from Guatemala City to Panama City
- Flights from Belize City to Panama City
- Flights from Cartagena to Panama City


