$261 Cheap flight deals from Raleigh (RDU) to Panama City (PTY)

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This Weekend's Flight Deals from Raleigh to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Aug 2 - Thu, Aug 6
RDU
Raleigh - Durham Intl.
PTY
Tocumen Intl.
$507 Roundtrip, found 16 hours ago
$507
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Sun, Aug 2 from Raleigh - Durham Intl. to Tocumen Intl., returning Thu, Aug 6, priced at $507 found 16 hours ago

Airfares from $261 One Way, $359 Round Trip from Raleigh to Panama City

Prices starting at $359 for return flights and $261 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Oct 1 - Mon, Oct 5
RDU
Raleigh
PTY
Panama City
$359 Roundtrip, found 2 days ago
$359
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Oct 1 from Raleigh to Panama City, returning Mon, Oct 5, priced at $359 found 2 days ago
Thu, Oct 1 - Mon, Oct 5
RDU
Raleigh
PTY
Panama City
$368 Roundtrip, found 2 days ago
$368
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Oct 1 from Raleigh to Panama City, returning Mon, Oct 5, priced at $368 found 2 days ago
Thu, Oct 1 - Mon, Oct 5
RDU
Raleigh
PTY
Panama City
$439 Roundtrip, found 2 days ago
$439
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Oct 1 from Raleigh to Panama City, returning Mon, Oct 5, priced at $439 found 2 days ago
Thu, Oct 1 - Mon, Oct 5
RDU
Raleigh
PTY
Panama City
$449 Roundtrip, found 2 days ago
$449
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Oct 1 from Raleigh to Panama City, returning Mon, Oct 5, priced at $449 found 2 days ago
Tue, Aug 4 - Thu, Aug 6
RDU
Raleigh
PTY
Panama City
$477 Roundtrip, found 19 hours ago
$477
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Tue, Aug 4 from Raleigh to Panama City, returning Thu, Aug 6, priced at $477 found 19 hours ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino
4.0-star property

Riande Aeropuerto Hotel & Casino

8.4/10 Very Good! (1,818 reviews)

Aug 28 - Sep 1

4 night stay

Raleigh (RDU) to Panama City (PTY)

United • Non-stop roundtrip • Coach
Price was $1,140, price is now $826 per person
$826
per person
found 1 day ago
Great

Reviewed on Jul 23, 2026

Central Hotel Panama Casco Viejo
4.0-star property

Central Hotel Panama Casco Viejo

9.2/10 Wonderful! (1,014 reviews)

Aug 28 - Sep 1

4 night stay

Raleigh (RDU) to Panama City (PTY)

United • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $1,736, price is now $937 per person
$937
per person
found 1 day ago
Hotel location is great, however, rooms are very noisy till late at night. Also rooms are super small and fridge and snacks are in the bathroom, which is pretty weird. Generally it was ok but more of a 4-star than a 5 -star hotel. Breakfast is nice,

Reviewed on Jul 24, 2026

Megapolis Hotel Panamá
4.5-star property

Megapolis Hotel Panamá

8.4/10 Very Good! (1,593 reviews)

Aug 28 - Sep 1

4 night stay

Raleigh (RDU) to Panama City (PTY)

United • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $1,843, price is now $1,035 per person
$1,035
per person
found 1 day ago
Kimberly, at the front desk was very rude, it seems she is not customer service oriented.

Reviewed on Jul 24, 2026

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More About Flying To Panama City from Raleigh

Route Information for Flights from Raleigh to Panama City

Origin Airport IATA Code
RDU
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Raleigh to Panama City

Whether you want to book cheap flights from Raleigh to Panama City or are looking for the perfect package holiday, Orbitz is your one-stop source. Taking the stress and expense out of travel, Orbitz helps you find the best fares for Raleigh to Panama City flights.

Make the Most of Your Vacation

Not only does Orbitz have cheap deals for Raleigh to Panama City flights, we can also help you plan your vacation in advance. Why wait in lengthy lines for tickets to shows, amusement parks, and other attractions when you could be making the most of your holiday? Add activities to your flight booking for fewer hassles once you arrive in Panama City.

Planning on the Go

Book your flights from Raleigh to Panama City wherever you are with the Orbitz app for Android and iPhone. Or simply use m.orbitz.com on your mobile browser to search and book the Raleigh to Panama City flights that you want. And if you’re running late, you check your flight status and baggage claim information on your mobile device too too.

Craft Your Perfect Vacation

Orbitz takes the stress out of vacation planning with great deals on flights from Raleigh to Panama City, hotels, car rentals, cruises, and more. Mix and match results for your perfect trip, or book a complete vacation package.

Keep Informed With Orbitz

With Orbitz’s free alerts service, you will stay informed of flight or services disruptions to your Raleigh to Panama City flights. The alerts can be sent straight to your mobile phone or email.

Frequently asked questions

What is the shortest flight from Raleigh to Panama City?
The shortest flight time from RDU to Panama Airport is 4 hours and 54 minutes, which gives you loads of time to indulge in a drink or get absorbed in a good movie.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.