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This Weekend's Flight Deals to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fares from $198 One Way, $301 Round Trip from Cartagena to Panama City

Prices starting at $301 for return flights and $198 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Need A Hotel In Panama City?

Hotels In Top Panama City Neighborhoods

Casco Viejo
33 hotels

American Trade Hotel

4.5 out of 5.0


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Global Hotel Panama

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Stay Near Exciting Panama City Attractions

More About Flying To Panama City from Cartagena

Route Information for Flights from Cartagena to Panama City

Origin Airport IATA CodeCTG
Destination Airport IATA CodePTY
Distance280 mi
Direct Flight AirlinesCopa Airlines, United Airlines
Earliest Flight Arrival8:41PM UTC
Latest Flight Arrival8:41PM UTC

Flights Review

Jun 24, 2018

Pleasantly surprised at the great service we had and friendly staff. Would definitely recommend. Love free checked bags, and full service during the flight

May 31, 2018

The staff were friendly and very helpful

Cartagena to Panama City

The perfect trip begins with Orbitz. From booking your flights from Cartagena to Panama City to finding the best hotels, Orbitz has got it covered.

Stress-free Searching

With an easy to use system, Orbitz takes the stress and expense out of travel. Not only does Orbitz match your Cartagena to Panama City flights to your ideal hotel, the Display Matrix shows your deals and discounts, including free nights and other savings.

Be One Step Ahead

Need to know what is going on at the airport before you get there? With Orbitz’s free alerts service, you can quickly find out about any booking changes, or flight from Cartagena to Panama City disruptions, saving you hours of wasted time. And if you are being picked up at the airport after your Cartagena to Panama City flights, have alerts sent straight to your contact’s mobile phone or email.

Cutting-Edge Mobile Tools

Find the best price on flights from Cartagena to Panama City with Orbitz’s mobile apps for iPhone and Android. Use on your mobile browser to check your gate, baggage allowance and delays, or find exclusive deals on hotels only available to mobile users.

We Work, you Rest and Play

Not only does booking with us ensure guaranteed low prices, but Orbitz does the hard work, leaving you to relax. Just tell us what you want, from Cartagena to Panama City flights, to great deals on hotels and car rental, and activities and tours, and we will do all the rest.

Flights from Cartagena to Panama City - Frequently Asked Questions

Are there non-stop flights from Cartagena to Panama City?

Copa Airlines Colombia will fly you nonstop from Cartagena (CTG-Rafael Nunez Intl.) to Balboa (BLB-Panama Pacifico Intl.), so you won't have to stress about changing planes or missing your next flight on this route.

What is the shortest flight from Cartagena to Panama City?

It can take just 1 hour and 18 minutes to jet from Cartagena (CTG-Rafael Nunez Intl.) to Panama City (PTY-Tocumen Intl.). Settle in and enjoy the trip, because you'll be stepping off the plane in the blink of an eye.

What airlines fly from Cartagena (and vicinity) to Panama City most frequently?

Copa Airlines Colombia offers the most flights along this route. This quality airline operates 15 flights from Cartagena (and vicinity) to Panama City each month.

If I am not able to travel due to COVID-19, can I cancel my flight to Panama City?

We get that traveling right now has its challenges, so it's good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Panama City have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you'll quickly see what options are available. Our Customer Service Portal is the place to go for more information.

Are there flights to Panama City with flexible change policies?

In most cases you'll have the option to reschedule your flight to Panama City without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the "no change fees" filter and book with confidence.

What is the cheapest day of the week to fly?

Consider flying out early in the week to save on your airfare. Orbitz data from 2019 shows that Tuesday is the cheapest day to depart, followed by Monday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.

What is the cheapest month to fly?

We won't keep you guessing, according to Orbitz data the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a fresh start to the new year. Be aware that the most expensive time to fly isn't the height of summer, as most people assume, but the festive month of December.

How can I save money on flights?

To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you'll generally get a much better deal. Those who tried this on Orbitz in 2019 saved over 50% on their airfares. Get mixing and matching today!

*According to flight demand on from January to December 2019. Savings are subject to change based on departure location, date and destination.

^Savings based on all package bookings with Flight + Hotel made on from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.