$188 Cheap flight deals from Guayaquil (GYE) to Panama City (PTY)

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This Weekend's Flight Deals from Guayaquil to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Sep 21 - Sun, Sep 28
GYE
Jose Joaquin de Olmedo Intl.
PTY
Tocumen Intl.
$518 Roundtrip, found 10 hours ago
$518
Roundtrip
found 10 hours ago
Select avianca flight, departing Sun, Sep 21 from Jose Joaquin de Olmedo Intl. to Tocumen Intl., returning Sun, Sep 28, priced at $518 found 10 hours ago

Airfares from $188 One Way, $340 Round Trip from Guayaquil to Panama City

Prices starting at $340 for return flights and $188 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Oct 28 - Thu, Oct 30
GYE
Guayaquil
PTY
Panama City
$340 Roundtrip, found 5 days ago
$340
Roundtrip
found 5 days ago
Select Copa flight, departing Tue, Oct 28 from Guayaquil to Panama City, returning Thu, Oct 30, priced at $340 found 5 days ago
Sun, Nov 2 - Wed, Nov 5
GYE
Guayaquil
PTY
Panama City
$352 Roundtrip, found 3 days ago
$352
Roundtrip
found 3 days ago
Select Copa flight, departing Sun, Nov 2 from Guayaquil to Panama City, returning Wed, Nov 5, priced at $352 found 3 days ago
Sun, Nov 2 - Wed, Nov 5
GYE
Guayaquil
PTY
Panama City
$362 Roundtrip, found 3 days ago
$362
Roundtrip
found 3 days ago
Select Copa flight, departing Sun, Nov 2 from Guayaquil to Panama City, returning Wed, Nov 5, priced at $362 found 3 days ago
Tue, Oct 28 - Thu, Oct 30
GYE
Guayaquil
PTY
Panama City
$374 Roundtrip, found 5 days ago
$374
Roundtrip
found 5 days ago
Select Copa flight, departing Tue, Oct 28 from Guayaquil to Panama City, returning Thu, Oct 30, priced at $374 found 5 days ago
Sat, Oct 18 - Mon, Oct 20
GYE
Guayaquil
PTY
Panama City
$383 Roundtrip, found 16 hours ago
$383
Roundtrip
found 16 hours ago
Select Copa flight, departing Sat, Oct 18 from Guayaquil to Panama City, returning Mon, Oct 20, priced at $383 found 16 hours ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama
5.0-star property

Hotel Riu Plaza Panama

9/10 Wonderful! (4,232 reviews)

Oct 23 - Oct 27

4 night stay

Guayaquil (GYE) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $815, price is now $606 per person
$606
per person
found 1 day ago
The breakfast was excellent and the staff was very friendly

Reviewed on Jul 28, 2025

Bristol Panama, a Registry Collection Hotel
5.0-star property

Bristol Panama, a Registry Collection Hotel

9.2/10 Wonderful! (1,003 reviews)

Oct 23 - Oct 27

4 night stay

Guayaquil (GYE) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $996, price is now $702 per person
$702
per person
found 1 day ago
The Bristol is my home in Panamá.

Reviewed on Jul 5, 2023

Megapolis Hotel Panamá
4.5-star property

Megapolis Hotel Panamá

8.4/10 Very Good! (1,056 reviews)

Oct 23 - Oct 27

4 night stay

Guayaquil (GYE) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $808, price is now $613 per person
$613
per person
found 1 day ago
Big hotel. Uber are very easy and cheap to get

Reviewed on Jul 9, 2025

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More About Flying To Panama City from Guayaquil

Route Information for Flights from Guayaquil to Panama City

Origin Airport IATA Code
GYE
Destination Airport IATA Code
PTY
Distance
775 mi
Direct Flight Airlines
KLM, Air France, Turkish Airlines, Copa Airlines, United Airlines
Earliest Flight Arrival
8:21PM UTC
Latest Flight Arrival
1:41AM UTC

Guayaquil to Panama City

For the best available deals on flights from Guayaquil to Panama City, look no further than Orbitz. Offering the perfect packages with cutting-edge mobile tools, Orbitz is your ideal destination.

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Frequently asked questions

Are there non-stop flights from Guayaquil to Panama City?
Work out your ideal travel dates, because there is. You can fly from Airport of Guayaquil to Panama City (PTY-Tocumen Intl.) in one simple journey with Copa Airlines.
What is the shortest flight from Guayaquil to Panama City?
Leave that movie marathon for some other time, because the journey from Guayaquil to Panama City can take as little as 2 hours and 6 minutes.
What airlines fly from Guayaquil to Panama City most frequently?
Copa Airlines has the most flights along this route. This popular airline operates 152 flights from Guayaquil to Panama City each month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.