$125 Cheap flight deals from Mexico City (MEX) to Panama City (PTY)

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This Weekend's Flight Deals from Mexico City to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Dec 14 - Wed, Jan 21
MEX
Mexico City Intl.
PTY
Tocumen Intl.
$415 Roundtrip, found 3 days ago
$415
Roundtrip
found 3 days ago
Select Aeromexico flight, departing Sun, Dec 14 from Mexico City Intl. to Tocumen Intl., returning Wed, Jan 21, priced at $415 found 3 days ago

Airfares from $125 One Way, $279 Round Trip from Mexico City to Panama City

Prices starting at $279 for return flights and $125 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Jan 1 - Mon, Jan 12
MEX
Mexico City
PTY
Panama City
$279 Roundtrip, found 13 hours ago
$279
Roundtrip
found 13 hours ago
Select Copa flight, departing Thu, Jan 1 from Mexico City to Panama City, returning Mon, Jan 12, priced at $279 found 13 hours ago
Thu, Jan 1 - Mon, Jan 12
MEX
Mexico City
PTY
Panama City
$314 Roundtrip, found 13 hours ago
$314
Roundtrip
found 13 hours ago
Select Aeromexico flight, departing Thu, Jan 1 from Mexico City to Panama City, returning Mon, Jan 12, priced at $314 found 13 hours ago
Tue, Dec 9 - Wed, Dec 24
MEX
Mexico City
PTY
Panama City
$315 Roundtrip, found 6 days ago
$315
Roundtrip
found 6 days ago
Select Aeromexico flight, departing Tue, Dec 9 from Mexico City to Panama City, returning Wed, Dec 24, priced at $315 found 6 days ago
Thu, Feb 12 - Thu, Feb 19
MEX
Mexico City
PTY
Panama City
$343 Roundtrip, found 3 days ago
$343
Roundtrip
found 3 days ago
Select avianca flight, departing Thu, Feb 12 from Mexico City to Panama City, returning Thu, Feb 19, priced at $343 found 3 days ago
Mon, Feb 23 - Fri, Feb 27
MEX
Mexico City
PTY
Panama City
$1,043 Roundtrip, found 2 days ago
$1,043
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Feb 23 from Mexico City to Panama City, returning Fri, Feb 27, priced at $1,043 found 2 days ago

More About Flying To Panama City from Mexico City

Route Information for Flights from Mexico City to Panama City

Origin Airport IATA Code
MEX
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Mexico City to Panama City

Mexico City to Panama City flights are offered at fantastic discount by Orbitz. Book air tickets now and cut those extra costs out of your travel budget to ensure a rewarding travel experience. With guaranteed low prices like these, can you afford to miss this discount?

Book cheap flights from Mexico City to Panama City

Cheap airfares are available on flights from Mexico City to Panama City. Use Orbitz to find the best flights that suit both your budget and the travel times that you need. Travelers who are looking for discounted rates on domestic or international flights need to look no further than Orbitz.

Orbitz goes mobile

As the world of technology rapidly expands around us, we are continuously finding new ways to improve our services, communications, and accessibility. With our cutting-edge mobile tools now available on Android, iPhone, and tablets, you can access detailed information on your bookings for flights from Mexico City to Panama City at any time or anywhere. See your itinerary for your Mexico City to Panama City flights, baggage and gate claim details, as well as hotel deals with our easy-to-use apps.

Get a great package with your Mexico City to Panama City flights

With frequent updates on your flight status, including delays and changes in bookings, traveling becomes more hassle-free than ever. Not only do we offer huge discounted deals on flights from Mexico City to Panama City, we also have fantastic savings on vacation packages, hotel room, cruises, activities, and car rentals so you can pick and choose and create the best travel package for you.

Frequently asked questions

Are there non-stop flights from Mexico City to Panama City?
There is. You can fly directly from Mexico City to Panama City with Copa Airlines. It's the only airline that travels nonstop from Mexico City, Distrito Federal (MEX-Mexico City Intl.) to Tocumen Intl. Airport (PTY).
What is the shortest flight from Mexico City to Panama City?
From Mexico City, the wonderful sights and sounds of Panama City are at least 3 hours and 33 minutes away. Book your favorite seat, or perhaps even one with extra legroom, and travel to your destination in comfort.
What airlines fly from Mexico City to Panama City most frequently?
Organize your Mexico City to Panama City trip with a Copa Airlines flight. With 152 each month, this airline has the most flights along this route.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.