$255 Cheap flight deals from Mexico City (MEX) to Panama City (PTY)

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This Weekend's Flight Deals from Mexico City to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Feb 7 - Tue, Feb 17
MEX
Mexico City Intl.
PTY
Tocumen Intl.
$360 Roundtrip, found 5 days ago
$360
Roundtrip
found 5 days ago
Select avianca flight, departing Sat, Feb 7 from Mexico City Intl. to Tocumen Intl., returning Tue, Feb 17, priced at $360 found 5 days ago

Airfares from $255 One Way, $360 Round Trip from Mexico City to Panama City

Prices starting at $360 for return flights and $255 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Mar 2 - Fri, Mar 6
MEX
Mexico City
PTY
Panama City
$360 Roundtrip, found 23 hours ago
$360
Roundtrip
found 23 hours ago
Select avianca flight, departing Mon, Mar 2 from Mexico City to Panama City, returning Fri, Mar 6, priced at $360 found 23 hours ago
Sat, May 30 - Mon, Jun 8
MEX
Mexico City
PTY
Panama City
$365 Roundtrip, found 1 day ago
$365
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Sat, May 30 from Mexico City to Panama City, returning Mon, Jun 8, priced at $365 found 1 day ago
Tue, Mar 3 - Tue, Mar 10
MEX
Mexico City
PTY
Panama City
$367 Roundtrip, found 2 hours ago
$367
Roundtrip
found 2 hours ago
Select Aeromexico flight, departing Tue, Mar 3 from Mexico City to Panama City, returning Tue, Mar 10, priced at $367 found 2 hours ago
Mon, Mar 2 - Fri, Mar 6
MEX
Mexico City
PTY
Panama City
$379 Roundtrip, found 23 hours ago
$379
Roundtrip
found 23 hours ago
Select avianca flight, departing Mon, Mar 2 from Mexico City to Panama City, returning Fri, Mar 6, priced at $379 found 23 hours ago
Sat, Feb 28 - Sun, Mar 1
MEX
Mexico City
PTY
Panama City
$383 Roundtrip, found 1 day ago
$383
Roundtrip
found 1 day ago
Select avianca flight, departing Sat, Feb 28 from Mexico City to Panama City, returning Sun, Mar 1, priced at $383 found 1 day ago

More About Flying To Panama City from Mexico City

Route Information for Flights from Mexico City to Panama City

Origin Airport IATA Code
MEX
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Mexico City to Panama City

Orbitz is the number one travel site for finding guaranteed low prices on Mexico City to Panama City flights. Not only do we have discount tickets on domestic and international tickets but our cutting-edge mobile tools keep you informed on the go.

Find Low Prices in One Place

Booking a trip from Mexico City to Panama City has never been easier. Not only will you find great deals on flights, we offer bargains on cruises, car rentals, top-notch hotels, and more. You can also research and add local activities in Panama City to your flight or hotel reservation to keep the kids happy and active.

Flight Booking, Alerts, and More on Your Mobile Device

Use our mobile app for your iPhone, iPad, or Android phone—or our mobile website m.orbitz.com—to find bargains on flights from Mexico City to Panama City wherever you are. Book your cheap Mexico City to Panama City flights and a hotel room too—even at the last minute. Orbitz also makes your life easier with free alerts that are sent to your mobile phone or email about delays to your upcoming flights from Mexico City to Panama City.

Don’t Miss out on Miles

Accumulate frequent flyer miles or points on your Mexico City to Panama City flights. It’s as simple as entering your frequent flyer number when you’re making your flight reservation on Orbitz to rack up miles on qualified flights from Mexico City to Panama City. You can save your frequent flyer numbers in your Orbitz account to save time during your next flight booking.

Frequently asked questions

Are there non-stop flights from Mexico City to Panama City?
There is. You can fly directly from Mexico City to Panama City with Copa Airlines. It's the only airline that travels nonstop from Mexico City, Distrito Federal (MEX-Mexico City Intl.) to Tocumen Intl. Airport (PTY).
What is the shortest flight from Mexico City to Panama City?
From Mexico City, the wonderful sights and sounds of Panama City are at least 3 hours and 33 minutes away. Book your favorite seat, or perhaps even one with extra legroom, and travel to your destination in comfort.
What airlines fly from Mexico City to Panama City most frequently?
Organize your Mexico City to Panama City trip with a Copa Airlines flight. With 152 each month, this airline has the most flights along this route.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.