$383 Cheap flight deals from Houston (HOU) to Panama City (PTY)

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This Weekend's Flight Deals from Houston to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Mar 20 - Tue, Mar 31
IAH
George Bush Intercontinental
PTY
Tocumen Intl.
$885 Roundtrip, found 3 days ago
$885
Roundtrip
found 3 days ago
Select avianca flight, departing Fri, Mar 20 from George Bush Intercontinental to Tocumen Intl., returning Tue, Mar 31, priced at $885 found 3 days ago
Fri, Mar 20 - Tue, Mar 31
IAH
George Bush Intercontinental
PTY
Tocumen Intl.
$885 Roundtrip, found 3 days ago
$885
Roundtrip
found 3 days ago
Select avianca flight, departing Fri, Mar 20 from George Bush Intercontinental to Tocumen Intl., returning Tue, Mar 31, priced at $885 found 3 days ago

Airfares from $383 One Way, $461 Round Trip from Houston to Panama City

Prices starting at $461 for return flights and $383 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Mar 28 - Tue, Apr 7
HOU
Houston
PTY
Panama City
$461 Roundtrip, found 5 days ago
$461
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Mar 28 from Houston to Panama City, returning Tue, Apr 7, priced at $461 found 5 days ago
Sat, Mar 28 - Tue, Apr 7
IAH
Houston
PTY
Panama City
$461 Roundtrip, found 5 days ago
$461
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Mar 28 from Houston to Panama City, returning Tue, Apr 7, priced at $461 found 5 days ago
Sat, Mar 28 - Tue, Apr 7
IAH
Houston
PTY
Panama City
$469 Roundtrip, found 5 days ago
$469
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Mar 28 from Houston to Panama City, returning Tue, Apr 7, priced at $469 found 5 days ago
Sat, Mar 28 - Tue, Apr 7
IAH
Houston
PTY
Panama City
$478 Roundtrip, found 5 days ago
$478
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Mar 28 from Houston to Panama City, returning Tue, Apr 7, priced at $478 found 5 days ago
Sat, Mar 28 - Tue, Apr 7
IAH
Houston
PTY
Panama City
$581 Roundtrip, found 5 days ago
$581
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Mar 28 from Houston to Panama City, returning Tue, Apr 7, priced at $581 found 5 days ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Villa Botero By Casa Mojito B&B
3.0-star property

Villa Botero By Casa Mojito B&B

9.8/10 Exceptional! (64 reviews)

Apr 21 - Apr 26

5 night stay

Houston (IAH) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $1,544, price is now $1,217 per person
$1,217
per person
found 1 day ago
After driving in Panama for six days, you would think we could find our way. We couldn't. After circling and using GPS we found the Villa. It is very quaint and cozy. The hosts are great. They even let us wash our dirty car. The Villa was quiet and well maintained. We would recommend it to others.

Reviewed on Apr 3, 2017

Megapolis Hotel Panamá
4.5-star property

Megapolis Hotel Panamá

8.4/10 Very Good! (1,441 reviews)

May 7 - May 12

5 night stay

Houston (IAH) to Panama City (PTY)

Avianca • Non-stop roundtrip • Coach
Price was $1,733, price is now $1,369 per person
$1,369
per person
found 1 day ago
Room was very clean, breakfast was great.Easy check in.

Reviewed on Nov 16, 2025

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More About Flying To Panama City from Houston

Route Information for Flights from Houston to Panama City

Origin Airport IATA Code
HOU
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Houston to Panama City

Looking for cheap Houston to Panama City flights? Orbitz has the cheapest air fares for flights from Houston to Panama City. Plus, with our cutting-edge mobile tools, travel planning has never been easier or more wallet-friendly.

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Use the Orbitz app or the mobile Orbitz site, m.orbtiz.com, to see information about your Houston to Panama City flights anytime you need it. Your itinerary is also sent to your email address for reference. Access updates on your flights from Houston to Panama City on your mobile device too, including delays and baggage claim details.

Cheap Air Ticket Prices Guaranteed

Orbitz is your number one source for low fares for Houston to Panama City flights. Our low price guarantee on domestic and international air tickets give you great savings for a perfect trip to Panama City. Need hotels too? You can book them last minute on your mobile phone.

Frequently asked questions

Are there non-stop flights from Houston to Panama City?
There sure is. United Airlines offers direct flights from Houston Airport to PTY, which makes getting from Houston to Panama City a piece of cake.
What is the shortest flight from Houston to Panama City?
With the trip from Houston to Panama City taking a minimum of 4 hours and 56 minutes, you'll have enough time to relax and enjoy the ride. Treat yourself to an in-flight wine or two and get cozy in your seat with a book or movie.
What airlines fly from Houston to Panama City most frequently?
United Airlines offers the most services from Houston to Panama City, with 60 flights each month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.