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This Weekend's Flight Deals to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fares from $340 One Way, $498 Round Trip from Quito to Panama City

Prices starting at $498 for return flights and $340 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Need A Hotel In Panama City?

Hotels In Top Panama City Neighborhoods

Casco Viejo
33 hotels

American Trade Hotel

4.5 out of 5.0


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Global Hotel Panama

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Stay Near Exciting Panama City Attractions

More About Flying To Panama City from Quito

Route Information for Flights from Quito to Panama City

Origin Airport IATA CodeUIO
Destination Airport IATA CodePTY
Distance638 mi
Direct Flight AirlinesKLM, Copa Airlines, Lufthansa
Earliest Flight Arrival1:32PM UTC
Latest Flight Arrival9:28PM UTC

Flights Review

Dec 1, 2019

Should add more options food for Vegans.

Nov 30, 2019

Excellent service, superb cabin staff, delicious food Thank you!

Sep 25, 2019

Good service thank you

Jan 7, 2019

Planes could definitely be updated with tv screens on each seat and a USB charger but it was still a comfortable flight.

Mar 23, 2018

Always really plasent flying by Copa

Feb 26, 2018

Copa should train United staff to understand how to run a good airline

Feb 17, 2018

First time I travel in Copa, and I am very satisfied

Feb 11, 2018

Flight on time, arrival before time ! New modern aircraft.

Quito to Panama City

Whether you want to book cheap flights from Quito to Panama City or are looking for the perfect package holiday, Orbitz is your one-stop source. Taking the stress and expense out of travel, Orbitz helps you find the best fares for Quito to Panama City flights.

Make the Most of Your Vacation

Not only does Orbitz have cheap deals for Quito to Panama City flights, we can also help you plan your vacation in advance. Why wait in lengthy lines for tickets to shows, amusement parks, and other attractions when you could be making the most of your holiday? Add activities to your flight booking for fewer hassles once you arrive in Panama City.

Planning on the Go

Book your flights from Quito to Panama City wherever you are with the Orbitz app for Android and iPhone. Or simply use on your mobile browser to search and book the Quito to Panama City flights that you want. And if you’re running late, you check your flight status and baggage claim information on your mobile device too too.

Craft Your Perfect Vacation

Orbitz takes the stress out of vacation planning with great deals on flights from Quito to Panama City, hotels, car rentals, cruises, and more. Mix and match results for your perfect trip, or book a complete vacation package.

Keep Informed With Orbitz

With Orbitz’s free alerts service, you will stay informed of flight or services disruptions to your Quito to Panama City flights. The alerts can be sent straight to your mobile phone or email.

Flights from Quito to Panama City - Frequently Asked Questions

Are there non-stop flights from Quito to Panama City?

There is. Copa Airlines offers direct flights from Quito (UIO-Mariscal Sucre Intl.) to Panama City (PTY-Tocumen Intl.), which makes flying from Quito to Panama City easy.

What is the shortest flight from Quito to Panama City?

It can take just 1 hour and 52 minutes to travel from Quito (UIO-Mariscal Sucre Intl.) to Panama City (PTY-Tocumen Intl.). Relax and enjoy those window views, because you'll be strolling through arrivals in no time.

What airlines fly from Quito (and vicinity) to Panama City most frequently?

Copa Airlines has the most flights along this route. This popular air carrier operates 30 flights from Quito Airport (UIO-Mariscal Sucre Intl.) to Panama City Airport (PTY-Tocumen Intl.) every month.

If I am not able to travel due to COVID-19, can I cancel my flight to Panama City?

We get that traveling right now has its challenges, so it's good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Panama City have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you'll quickly see what options are available. Our Customer Service Portal is the place to go for more information.

Are there flights to Panama City with flexible change policies?

In most cases you'll have the option to reschedule your flight to Panama City without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the "no change fees" filter and book with confidence.

What is the cheapest day of the week to fly?

Consider flying out early in the week to save on your airfare. Orbitz data from 2019 shows that Tuesday is the cheapest day to depart, followed by Monday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.

What is the cheapest month to fly?

We won't keep you guessing, according to Orbitz data the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a fresh start to the new year. Be aware that the most expensive time to fly isn't the height of summer, as most people assume, but the festive month of December.

How can I save money on flights?

To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you'll generally get a much better deal. Those who tried this on Orbitz in 2019 saved over 50% on their airfares. Get mixing and matching today!

*According to flight demand on from January to December 2019. Savings are subject to change based on departure location, date and destination.

^Savings based on all package bookings with Flight + Hotel made on from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.