Important: This destination may have COVID-19 travel restrictions in place, including specific restrictions for lodging. Check any national, local, and health advisories for this destination before you book.

Cheap Flight Deals From Medellin (MDE) to Panama City (PTY) Starting at $135

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This Weekend's Flight Deals from Medellin to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Airfares from $135 One Way, $255 Round Trip from Medellin to Panama City

Prices starting at $255 for return flights and $135 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

More About Flying To Panama City from Medellin

Route Information for Flights from Medellin to Panama City

Origin Airport IATA Code MDE
Destination Airport IATA Code PTY
Distance 336 mi
Direct Flight Airlines Copa Airlines, United Airlines
Earliest Flight Arrival 11:44AM UTC
Latest Flight Arrival 1:22AM UTC

Medellin to Panama City

Looking for cheap Medellin to Panama City flights? Orbitz has the cheapest air fares for flights from Medellin to Panama City. Plus, with our cutting-edge mobile tools, travel planning has never been easier or more wallet-friendly.

Mobile Deals and Steals

Orbitz is dedicated to providing low fares on Medellin to Panama City flights. Now you can find the latest deals on-the-go with Orbitz’s mobile apps for iPhone, iPad, Android phones, and tablets. Instantly see discounted rates for hotels, cruises, vacations, and air tickets for a great vacation.

Book Hotels With Confidence

When you’re looking for hotel rooms to go with your bargain flights from Medellin to Panama City, Orbitz provides you descriptions, photos, reviews, and location maps so you know exactly what you are booking. With easy-to-use Orbitz map tools, you can search for nearby hotels on your mobile device.

Access Your Flight Information Anytime

Use the Orbitz app or the mobile Orbitz site, m.orbtiz.com, to see information about your Medellin to Panama City flights anytime you need it. Your itinerary is also sent to your email address for reference. Access updates on your flights from Medellin to Panama City on your mobile device too, including delays and baggage claim details.

Cheap Air Ticket Prices Guaranteed

Orbitz is your number one source for low fares for Medellin to Panama City flights. Our low price guarantee on domestic and international air tickets give you great savings for a perfect trip to Panama City. Need hotels too? You can book them last minute on your mobile phone.

Flights from Medellin to Panama City - Frequently Asked Questions

Am I able to catch a flight from Medellin to Panama City now?

Go right to our Covid-19 Travel Advisor for the most up-to-date info on quarantine and travel restrictions when getting a flight from Medellin to Panama City.

Are there non-stop flights from Medellin to Panama City?

Yes, there is. Copa Airlines will fly you directly from Jose Maria Cordova Intl. Airport (MDE) to PTY, so you won't have to stress about lengthy layovers or missing that connecting flight.

What is the shortest flight from Medellin to Panama City?

If the weather is good and all goes as planned, you could be coming in to land at PTY from Medellin Airport in just 2 hours and 41 minutes. With such a speedy flight time, contemplate taking just hand luggage.

What airlines fly from Medellin to Panama City most frequently?

Plan your Medellin to Panama City journey with a Copa Airlines flight. With 91 each month, this airline offers the most flights between these two destinations.

If I am not able to travel due to COVID-19, can I cancel my flight to Panama City?

We get that traveling right now has its challenges, so it's good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Panama City have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you'll quickly see what options are available. Our Customer Service Portal is the place to go for more information.

Are there flights to Panama City with flexible change policies?

In most cases you'll have the option to reschedule your flight to Panama City without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the "no change fees" filter and book with confidence.

What is the cheapest day of the week to fly?

Consider flying out early in the week to save on your airfare. Orbitz data from 2020 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.

What is the cheapest month to fly?

We won't keep you guessing, according to Orbitz data the cheapest month to fly is August. Perfect for those who need a weekend getaway, or just a break from it all before the weather changes. Be aware that the most expensive time to fly is the height of summer, with ticket prices peaking in the month of June.

How can I save money on flights?

To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you'll generally get a much better deal. Those who tried this on Orbitz in 2020 saved up to 45% on their airfares. Get mixing and matching today!

*According to flight demand on Orbitz.com from January to December 2020. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.