$38 Cheap flight deals from Medellín (MDE) to Cali (CLO)

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This Weekend's Flight Deals from Medellín to Cali

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Aug 16 - Sun, Aug 23
MDE
José María Córdova Intl.
CLO
Alfonso Bonilla Aragon Intl.
$127 Roundtrip, found 10 hours ago
$127
Roundtrip
found 10 hours ago
Select Jetsmart SPA flight, departing Sun, Aug 16 from José María Córdova Intl. to Alfonso Bonilla Aragon Intl., returning Sun, Aug 23, priced at $127 found 10 hours ago

Airfares from $38 One Way, $77 Round Trip from Medellín to Cali

Prices starting at $77 for return flights and $38 for one-way flights to Cali were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Oct 1 - Sun, Oct 4
MDE
Medellín
CLO
Cali
$77 Roundtrip, found 1 day ago
$77
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Thu, Oct 1 from Medellín to Cali, returning Sun, Oct 4, priced at $77 found 1 day ago
Fri, Nov 13 - Mon, Nov 16
MDE
Medellín
CLO
Cali
$82 Roundtrip, found 5 days ago
$82
Roundtrip
found 5 days ago
Select Jetsmart SPA flight, departing Fri, Nov 13 from Medellín to Cali, returning Mon, Nov 16, priced at $82 found 5 days ago
Thu, Aug 27 - Tue, Nov 24
MDE
Medellín
CLO
Cali
$84 Roundtrip, found 2 hours ago
$84
Roundtrip
found 2 hours ago
Select Jetsmart SPA flight, departing Thu, Aug 27 from Medellín to Cali, returning Tue, Nov 24, priced at $84 found 2 hours ago
Wed, Aug 26 - Mon, Aug 31
MDE
Medellín
CLO
Cali
$90 Roundtrip, found 3 days ago
$90
Roundtrip
found 3 days ago
Select Jetsmart SPA flight, departing Wed, Aug 26 from Medellín to Cali, returning Mon, Aug 31, priced at $90 found 3 days ago
Thu, Aug 27 - Tue, Nov 24
MDE
Medellín
CLO
Cali
$96 Roundtrip, found 2 hours ago
$96
Roundtrip
found 2 hours ago
Select Jetsmart SPA flight, departing Thu, Aug 27 from Medellín to Cali, returning Tue, Nov 24, priced at $96 found 2 hours ago

Cali economy flight packages

Price found within the past 48 hours. Click for updated prices.
Hotel Avenida 3 Real
3.0-star property

Hotel Avenida 3 Real

8.8/10 Excellent! (23 reviews)

Sep 25 - Sep 29

4 night stay

Medellín (MDE) to Cali (CLO)

B & H Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $340, price is now $170 per person
$170
per person
found 1 day ago
Muy buen servicio

Reviewed on Jul 29, 2026

ZiOne Luxury Hotel Pereira
3.5-star property

ZiOne Luxury Hotel Pereira

9/10 Wonderful! (215 reviews)

Sep 25 - Sep 29

4 night stay

Medellín (MDE) to Cali (CLO)

B & H Airlines • Roundtrip • Coach
Price was $313, price is now $248 per person
$248
per person
found 1 day ago

NH Cali Royal
4.0-star property

NH Cali Royal

8.4/10 Very Good! (1,002 reviews)

Sep 25 - Sep 29

4 night stay

Medellín (MDE) to Cali (CLO)

B & H Airlines • Roundtrip • Coach
Price was $265, price is now $224 per person
$224
per person
found 1 day ago

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More About Flying To Cali from Medellín

Route Information for Flights from Medellín to Cali

Origin Airport IATA Code
MDE
Destination Airport IATA Code
CLO
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Medellín to Cali

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Orbitz looks for the best deals on Medellín to Cali flights for you. Mix and match airlines for your departing and return flights to fit your travel schedule and budget.

Frequently asked questions

Are there non-stop flights from Medellin to Cali?
There certainly are. As a matter of fact, there are 3 airlines that will take you nonstop from Medellin Airport to Cali (CLO-Alfonso Bonilla Aragon Intl.). Lock in your ticket with one of these well-known carriers:

  • LATAM Airlines
  • Viva Air Colombia
  • Avianca

What is the shortest flight from Medellin to Cali?
The trip from Medellin to Cali can be as fast as 1 hour. With an easy flight time like this, why not grab some friends and organize a spontaneous getaway?
What airlines fly from Medellin to Cali most frequently?
Consider booking a ticket with LATAM Airlines (LA), which flies frequently along this route. This airline offers 86 flights every month between MDE and Alfonso Bonilla Aragon Intl. Airport (CLO). Alternatively, reserve your favorite seat with Viva Air Colombia (VH). You'll have 69 monthly flights between Medellin and Cali to take your pick of with this airline.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.