Book 5 Star Hotels in Panama City
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Featured Panama City 5 Stars Hotels
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
Free Cancellation
Reserve now, pay when you stay
0.28 mi from city center
$104 nightly
The price is $115 total per night
$115 total
Nov 5 - Nov 6
Total with taxes and fees
At Hotel Riu Plaza Panama, guests enjoy an outdoor pool, a gym, and free WiFi in public areas. Valet parking is offered for PAB 12 per night. The front desk is staffed 24/7 to help with securing valuables, tours or tickets, and luggage storage. Other amenities at this luxury hotel include meeting rooms, conference space, and a business center.
Pool
Breakfast included
Sheraton Grand Panama
Via Israel And 77th Street, Panama City, Panama
1.73 mi from city center
$127 nightly
The price is $139 total per night
$139 total
Nov 1 - Nov 2
Total with taxes and fees
Guests of Sheraton Grand Panama enjoy a full-service spa, an outdoor pool, and a 24-hour gym. You can take advantage of free parking, along with limo/town car service. Multilingual staff at the front desk are standing by 24/7 to help with luggage storage, dry cleaning/laundry, and concierge services. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this spa resort include a sauna, outdoor tennis courts, and free WiFi in public areas.
Pool
Spa
Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Free Cancellation
Reserve now, pay when you stay
0.33 mi from city center
$88 nightly
The price is $97 total per night
$97 total
Oct 30 - Oct 31
Total with taxes and fees
Guests staying at Waymore Hotel Spa & Casino enjoy access to a full-service spa, an outdoor pool, and free WiFi in public areas. Onsite parking is available, both free self and paid valet parking (USD 10 per night)—also useful is an airport shuttle (available 24 hours) for USD 50 per person one-way. The front desk is staffed 24 hours a day to help with concierge services and luggage storage. Other amenities at this spa bed & breakfast include meeting rooms, laundry facilities, and a vending machine.
Pool
Breakfast included
The Executive Hotel
Calle 52, Aquilino de La Guardia, Panama City, Panama
Free Cancellation
0.04 mi from city center
$86 nightly
The price is $95 total per night
$95 total
Oct 22 - Oct 23
Total with taxes and fees
Guests of The Executive Hotel have access to an outdoor pool, a gym, and a steam room. There's free parking, and an airport shuttle (available on request) for USD 30 per person one-way. Multilingual staff at the front desk are standing by 24/7 to help with tours or tickets, securing valuables, and luggage storage. Additional amenities include free WiFi in public areas, conference space, and a business center.
Pool
Breakfast included
Megapolis Hotel Panamá
Avenida Balboa, Panama City
Free Cancellation
Reserve now, pay when you stay
0.59 mi from city center
$111 nightly
The price is $122 total per night
$122 total
Oct 25 - Oct 26
Total with taxes and fees
Guests of Megapolis Hotel Panamá have access to a full-service spa, a casino, and an outdoor pool. There's free valet parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage, tours or tickets, and dry cleaning/laundry. Other amenities at this luxury hotel include a sauna, a rooftop terrace, and free WiFi in public areas.
Pool
Hot Tub
Principe Hotel and Suites
Via Argentina, Panama City, Panama
Free Cancellation
Reserve now, pay when you stay
0.42 mi from city center
$51 nightly
The price is $56 total per night
$56 total
Oct 13 - Oct 14
Total with taxes and fees
At Principe Hotel and Suites, guests have access to an outdoor pool, free WiFi in public areas, and meeting rooms. There's free parking, and an airport shuttle (available 24 hours) for PAB 30 per vehicle one-way. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, concierge services, and securing valuables. Additional amenities include a business center, a terrace, and laundry facilities.
Pool
Parking included
Studio Coliving
Av. Ricardo Arango y, Av. Federico Boyd, Panama City, Panama
Free Cancellation
Reserve now, pay when you stay
0.15 mi from city center
$44 nightly
The price is $49 total per night
$49 total
Oct 12 - Oct 13
Total with taxes and fees
Guests of Studio Coliving have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is offered for USD 5 per day. The front desk has multilingual staff on hand 24/7 to help with tours or tickets, securing valuables, and luggage storage. Other amenities at this luxury hotel include meeting rooms, a conference center, and a 24-hour business center.
Pool
Free WiFi
Waldorf Astoria Panama
47th St. & Uruguay Street, Panama City, Panama
Free Cancellation
Reserve now, pay when you stay
0.33 mi from city center
$188 nightly
The price is $207 total per night
$207 total
Nov 1 - Nov 2
Total with taxes and fees
Guests of Waldorf Astoria Panama enjoy a full-service spa, an outdoor pool, and a 24-hour gym. Valet parking is available for PAB 15 per night. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Other amenities at this luxury hotel include free WiFi in public areas, conference space, and a 24-hour business center.
Pool
Spa
Marriott Panama Hotel
Roosevelt Ave., Allbrook Mall, Panama City, Panama
Free Cancellation
Reserve now, pay when you stay
2.01 mi from city center
$134 nightly
The price is $148 total per night
$148 total
Oct 18 - Oct 19
Total with taxes and fees
Marriott Panama Hotel features an outdoor pool, a children's pool, and a 24-hour gym. Free offsite parking is available if you drive. Multilingual staff at the front desk are standing by 24/7 to help with tours or tickets, dry cleaning/laundry, and luggage storage. Additional amenities include a rooftop terrace, free WiFi in public areas, and a conference center.
Pool
Pet friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best 5 star hotels in Panama City
Guarantee yourself a relaxing time when you book the best of the best: 5 star hotels in Panama City. After all, treating yourself to the finer things is what vacations are about.
What are the criteria for a 5 star hotel?
5 star hotel requirements include distinctive services and amenities that surpass all others. These Panama City hotels bring an incomparable degree of quality and attention to detail, with guest satisfaction being top priority. Your 5 star hotel should be dressed to impress, with design details like marble surfaces and hi-tech fixtures.
What amenities can I expect at a 5 star hotel?
Panama City 5 star hotels and resorts typically offer luxury amenities such as:
- Gourmet restaurant
- Full-service fitness center with pool
- Luxury spa
- Welcome gifts upon arrival
- Top-of-the-line beds and linens
- Designer personal care products
- Premium cable, free Wi-Fi and device docking stations
How do I find an amazing 5 star hotel?
Finding 5 star hotel deals in Panama City with Orbitz is as easy as your stay will be. For the top-shelf vacation you deserve, we’ll help you choose the right hotel in the right place:
- Search hotels by price, ranging from $49 to $207
- Find the best-loved hotels through word-of-mouth advice when you check out over reviews by Orbitz travelers
- Choose from 1,474 5 star hotels in Panama City!
Panama City hotels essential information
Accommodation | 1,474 hotels |
|---|---|
Lowest Price | $49 |
Highest Price | $207 |
Popular hotels | Hotel Riu Plaza Panama, Sheraton Grand Panama, Waymore Hotel Spa & Casino, The Executive Hotel, Megapolis Hotel Panamá, Principe Hotel and Suites, Studio Coliving, Waldorf Astoria Panama, Marriott Panama Hotel |
Recent Reviews
Megapolis Hotel Panamá
5/5 Excellent
"Spacious and convenient "
A verified traveler stayed at Megapolis Hotel Panamá
Posted 4 days ago
More to Explore
- Hotels near Via Espana
- Hotels near Amador Causeway
- Hotels near National Theater
- Casino Resorts & in El Cangrejo
- Cheap Hotels in El Cangrejo
- Hotels with Bar in El Cangrejo
- Pet Friendly Hotels in El Cangrejo
- El Cangrejo Hotels
- Hotels near El Dorado Mall
- Casino Resorts & in Panamá Province
- Hotels with a Wedding Venue in Panamá Province
- Panamá Province Hotels
- Punta Pacifica Hotels
- Hotels near Cinta Costera
- Obarrio Hotels
- Campo Alegre Hotels
- San Francisco Hotels
- Hotels with Bar in Bella Vista
- Hotels with Hot Tubs in Bella Vista
- Ski Resorts & in Bella Vista
- Bella Vista Hotels
- Parque Lefevre Hotels
- Hotels near Albrook Shopping Mall
- Marbella Hotels
- Hotels near Multiplaza Pacific Mall
- 3 Star Hotels in Casco Viejo
- Beach Resorts & in Casco Viejo
- Boutique Hotels in Casco Viejo
- Cheap Hotels in Casco Viejo
- Gay Friendly Hotels in Casco Viejo
- Hotels with Airport Transfers in Casco Viejo
- Hotels with WiFi in Casco Viejo
- Hotels with Room Service in Casco Viejo
- Pet Friendly Hotels in Casco Viejo
- Hotels with a Wedding Venue in Casco Viejo
- Casco Viejo Hotels
- Adventure Hotels in Causeway Islands
- Hotels with Shopping in Causeway Islands
- Causeway Islands Hotels
- Rio Abajo Hotels
- Hotels near Marcos A. Gelabert Intl.
- Bethania Hotels
- Hotels near Fiesta Casino
- Balboa Hotels
- Hotels with Bar in Punta Paitilla
- Punta Paitilla Hotels
- Hotels near ATLAPA Conventions Center
- Hotels near Amador Convention Center
- Hotels near Bingo 90
- Hotels near Crown Casino
- Flights to Panamá Province
- Flights from Boston to Causeway Islands
- Flights from Albany (ALB) to Panama City (PAC)
- Flights from Balboa (BLB) to Panama City (PAC)
- Flights from Cuiaba (CGB) to Panama City (PAC)
- Flights from Changuinola (CHX) to Panama City (PAC)
- Flights from Ciudad Real (CQM) to Panama City (PAC)
- Flights from Esmeraldas (ESM) to Panama City (PAC)
- Flights from Sioux Falls (FSD) to Panama City (PAC)
- Flights from Jacksonville (JAX) to Panama City (PAC)
- Flights from Jamestown (JMS) to Panama City (PAC)
- Flights from Kochi (KCZ) to Panama City (PAC)
- Flights from Midland (MAF) to Panama City (PAC)
- Flights from Orlando (MCO) to Panama City (PAC)
- Flights from Miami (MIA) to Panama City (PAC)
- Flights from Muscle Shoals (MSL) to Panama City (PAC)
- Flights from Norfolk (ORF) to Panama City (PAC)
- Flights from Pula (PUY) to Panama City (PAC)
- Flights from Rock Sound (RSD) to Panama City (PAC)
- Flights from Winnipeg (YWG) to Panama City (PAC)
- Flights from Whitehorse (YXY) to Panama City (PAC)
- Flights from Victoria (YYJ) to Panama City (PAC)
- Car rentals near Santa Ana
- Car rentals near Punta Pacifica
- Car rentals near San Francisco
- Car rentals near Bella Vista
- Car rentals near Parque Lefevre
- Car rentals near Marbella
- Alamo Rent A Car Rental Cars in Casco Viejo
- Avis Rental Cars in Casco Viejo
- Budget Rental Cars in Casco Viejo
- Enterprise Rental Cars in Casco Viejo
- Fox Rental Cars Rental Cars in Casco Viejo
- National Car Rental Rental Cars in Casco Viejo
- Payless Rental Cars in Casco Viejo
- Sixt Rental Cars in Casco Viejo
- Thrifty Car Rental Rental Cars in Casco Viejo
- Auto Rent Rental Cars in Causeway Islands
- Car rentals near Causeway Islands
- Discount Car Rentals Rental Cars in Causeway Islands
- Car rentals near Pueblo Nuevo