Cheap flights from MDT to SAN (Harrisburg Intl. to San Diego Intl.)

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Cheap Flights from MDT to SAN starting at $254 One Way, $369 Round Trip

Prices starting at $369 for return flights and $254 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Aug 6 - Mon, Aug 10
MDT
Harrisburg
SAN
San Diego
$369 Roundtrip, found 1 day ago
$369
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Aug 6 from Harrisburg to San Diego, returning Mon, Aug 10, priced at $369 found 1 day ago
Wed, May 27 - Wed, Jun 3
MDT
Harrisburg
SAN
San Diego
$380 Roundtrip, found 6 days ago
$380
Roundtrip
found 6 days ago
Select United flight, departing Wed, May 27 from Harrisburg to San Diego, returning Wed, Jun 3, priced at $380 found 6 days ago
Wed, May 27 - Wed, Jun 3
MDT
Harrisburg
SAN
San Diego
$385 Roundtrip, found 6 days ago
$385
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, May 27 from Harrisburg to San Diego, returning Wed, Jun 3, priced at $385 found 6 days ago
Fri, Aug 7 - Mon, Aug 10
MDT
Harrisburg
SAN
San Diego
$394 Roundtrip, found 5 days ago
$394
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Aug 7 from Harrisburg to San Diego, returning Mon, Aug 10, priced at $394 found 5 days ago
Wed, Aug 5 - Wed, Aug 12
MDT
Harrisburg
SAN
San Diego
$394 Roundtrip, found 1 day ago
$394
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Aug 5 from Harrisburg to San Diego, returning Wed, Aug 12, priced at $394 found 1 day ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$169 nightly
The price is $194 total per night from May 24 to May 25
$194 total
May 24 - May 25
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,529 reviews)
"Everything was wonderful about the stay. From check-in to check-out all my needs were taken care of at the highest level. Of special note is the shuttle. If you are primarily at the property, the shittle will provide transportation to the local restaurants and wedding venues and the airport. It is ..."

Reviewed on May 19, 2026

Sheraton San Diego Resort
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
$168 nightly
The price is $194 total per night from May 27 to May 28
$194 total
May 27 - May 28
Total with taxes and fees
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (2,066 reviews)
"Very convenient location. A great value!"

Reviewed on May 19, 2026

The Sofia Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$174 nightly
The price is $201 total per night from May 25 to May 26
$201 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,144 reviews)
"I did not go to the pool nor ate breakfast"

Reviewed on May 20, 2026

Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
$168 nightly
The price is $194 total per night from May 27 to May 28
$194 total
May 27 - May 28
Total with taxes and fees
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (2,066 reviews)
"Very convenient location. A great value!"

Reviewed on May 19, 2026

The Sofia Hotel
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$259 nightly
The price is $300 total per night from May 22 to May 23
$300 total
May 22 - May 23
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (2,815 reviews)
"I was there for a conference. Food was good"

Reviewed on May 19, 2026

Manchester Grand Hyatt San Diego
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
$264 nightly
The price is $303 total per night from May 21 to May 22
$303 total
May 21 - May 22
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,606 reviews)
"Very beautiful, peaceful and relaxing place overall Kid and pet friendly this place is a great vacation spot 9/10"

Reviewed on May 20, 2026

Paradise Point Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$174 nightly
The price is $201 total per night from May 25 to May 26
$201 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,144 reviews)
"I did not go to the pool nor ate breakfast"

Reviewed on May 20, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$169 nightly
The price is $194 total per night from May 24 to May 25
$194 total
May 24 - May 25
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,529 reviews)
"Everything was wonderful about the stay. From check-in to check-out all my needs were taken care of at the highest level. Of special note is the shuttle. If you are primarily at the property, the shittle will provide transportation to the local restaurants and wedding venues and the airport. It is ..."

Reviewed on May 19, 2026

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$141 nightly
The price is $162 total per night from May 25 to May 26
$162 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,062 reviews)
"Clean hotel"

Reviewed on May 19, 2026

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$108 nightly
The price is $124 total per night from May 21 to May 22
$124 total
May 21 - May 22
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.6/10 Excellent! (1,405 reviews)
"Desk personnel and housekeeping staff are always so nice and helpful. Room was spotlessly cleaned every day. Great location for us when visiting family and friends in San Diego. Pleasant Inn is the perfect name for the hotel."

Reviewed on May 18, 2026

Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$62 nightly
The price is $71 total per night from May 21 to May 22
$71 total
May 21 - May 22
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.6/10 (2,116 reviews)
"U"

Reviewed on May 20, 2026

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$104 nightly
The price is $119 total per night from May 25 to May 26
$119 total
May 25 - May 26
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,698 reviews)
"room was clean and the staff were all over the top customer service. we didn't use any of the amenities as we were just in and out..short stay"

Reviewed on May 19, 2026

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$232 nightly
The price is $267 total per night from May 31 to Jun 1
$267 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,080 reviews)
"So here’s my honest review . The resort is perfectly located. Steps away from own beach , garden is gorgeous. However here’s my take: for as much as we paid for our room and the additional “resort fee” each day. The rooms were very dated ! Old carpet, old furniture, horrible water pressure in the ..."

Reviewed on May 20, 2026

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$224 nightly
The price is $257 total per night from May 25 to May 26
$257 total
May 25 - May 26
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,369 reviews)
"Yes Never had breakfast"

Reviewed on May 20, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$255 nightly
The price is $294 total per night from May 25 to May 26
$294 total
May 25 - May 26
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,258 reviews)

Families like: Outdoor pool, game room, on the beach, bicycle rentals

Travelers say...
"Beautiful hotel grounds"

Reviewed on May 15, 2026

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MDT to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MDT Address & GPS
Address:
One Terminal Drive
Middletown PA, 17057
United States
IATA Code:
MDT
Longitude:
-76.756057
Latitude:
40.196008
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Harrisburg Intl. Airport to San Diego Intl. Airport (SAN)?
Flying from MDT to San Diego Airport means you're going to have to switch planes. But hey — that's OK. American Airlines, Delta Air Lines and United Airlines offer flights with a single stopover.
What is the shortest flight from Harrisburg Intl. Airport (MDT) to San Diego Airport?
Use the opportunity to sit back and chill out on your way from Harrisburg to San Diego. The quickest flight time from Harrisburg Intl. Airport to SAN is 7 hours and 5 minutes, which gives you loads of time to enjoy a wine or lose yourself in a good book.
How many hours flight from Harrisburg Intl. Airport to San Diego Intl. Airport (SAN)?
It usually takes around 7 hours and 9 minutes to fly from Harrisburg Intl. Airport (MDT) to San Diego Airport. You'll be airborne for a good amount of time, so take your own entertainment, like a good read or a podcast.
What airlines have the most flights from MDT to San Diego Intl. Airport (SAN)?
Right now, you can't fly nonstop from Harrisburg to San Diego. However, you will be able to book a flight with one or more stops. It's not all bad — use the break to stretch your legs or go in search of a nice meal!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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