Cheap flights from MDT to SAN (Harrisburg Intl. to San Diego Intl.)

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Cheap Flights from MDT to SAN starting at $335 One Way, $369 Round Trip

Prices starting at $369 for return flights and $335 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jan 23 - Wed, Feb 3
MDT
Harrisburg
SAN
San Diego
$369 Roundtrip, found 1 day ago
$369
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Jan 23 from Harrisburg to San Diego, returning Wed, Feb 3, priced at $369 found 1 day ago
Sat, Jan 23 - Wed, Feb 3
MDT
Harrisburg
SAN
San Diego
$369 Roundtrip, found 1 day ago
$369
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jan 23 from Harrisburg to San Diego, returning Wed, Feb 3, priced at $369 found 1 day ago
Sat, Jan 23 - Wed, Feb 3
MDT
Harrisburg
SAN
San Diego
$369 Roundtrip, found 1 day ago
$369
Roundtrip
found 1 day ago
Select United flight, departing Sat, Jan 23 from Harrisburg to San Diego, returning Wed, Feb 3, priced at $369 found 1 day ago
Sat, Jan 23 - Wed, Feb 3
MDT
Harrisburg
SAN
San Diego
$371 Roundtrip, found 1 day ago
$371
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Jan 23 from Harrisburg to San Diego, returning Wed, Feb 3, priced at $371 found 1 day ago
Sat, Sep 19 - Wed, Sep 30
MDT
Harrisburg
SAN
San Diego
$373 Roundtrip, found 6 days ago
$373
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Sep 19 from Harrisburg to San Diego, returning Wed, Sep 30, priced at $373 found 6 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$222 nightly
The price is $255 total per night from Aug 2 to Aug 3
$255 total
Aug 2 - Aug 3
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,560 reviews)
"Five Star Experience ***** You can not go wrong with this hotel. ABSOLUTELY AMAZING! I am not staying anywhere else when I go to San Diego."

Reviewed on Jul 10, 2026

Sheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Jul 19 to Jul 20
$211 total
Jul 19 - Jul 20
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,287 reviews)
"Balcony view was amazing. No microwave. Friendly staff. Clean room.Walking distance to Seaport Village was close by, along with other attractions. Will plan on staying here again."

Reviewed on Jul 10, 2026

Wyndham San Diego Bayside
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

2.5 out of 5
2485 Hotel Circle Place San Diego CA
$127 nightly
The price is $146 total per night from Aug 2 to Aug 3
$146 total
Aug 2 - Aug 3
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (2,798 reviews)
"Room was double booked, staff was very welcoming"

Reviewed on Jul 10, 2026

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Jul 19 to Jul 20
$211 total
Jul 19 - Jul 20
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,287 reviews)
"Balcony view was amazing. No microwave. Friendly staff. Clean room.Walking distance to Seaport Village was close by, along with other attractions. Will plan on staying here again."

Reviewed on Jul 10, 2026

Wyndham San Diego Bayside
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
$325 nightly
The price is $374 total per night from Aug 9 to Aug 10
$374 total
Aug 9 - Aug 10
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,724 reviews)
"Unexpected $50 nightly per car parking fee and an add on $50 per day resort fee. It's a good place but no longer worth the add on fees."

Reviewed on Jul 10, 2026

Paradise Point Resort & Spa
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
$225 nightly
The price is $261 total per night from Jul 19 to Jul 20
$261 total
Jul 19 - Jul 20
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (4,016 reviews)
"Clean room. The location was perfect for our visit(going to Petco park). The pool is heated which I wish I would have known ahead of time, it looked great. Everyone was friendly."

Reviewed on Jul 10, 2026

Hard Rock Hotel San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Jul 19 to Jul 20
$211 total
Jul 19 - Jul 20
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,287 reviews)
"Balcony view was amazing. No microwave. Friendly staff. Clean room.Walking distance to Seaport Village was close by, along with other attractions. Will plan on staying here again."

Reviewed on Jul 10, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$222 nightly
The price is $255 total per night from Aug 2 to Aug 3
$255 total
Aug 2 - Aug 3
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,560 reviews)
"Five Star Experience ***** You can not go wrong with this hotel. ABSOLUTELY AMAZING! I am not staying anywhere else when I go to San Diego."

Reviewed on Jul 10, 2026

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$171 nightly
The price is $196 total per night from Jul 19 to Jul 20
$196 total
Jul 19 - Jul 20
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,079 reviews)
"Room was clean and very quiet considering its proximity to the highway and airport. The staff was wonderful! Transportation to and from the airport and the car rental center was an added bonus!"

Reviewed on Jul 7, 2026

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$110 nightly
The price is $126 total per night from Aug 9 to Aug 10
$126 total
Aug 9 - Aug 10
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.6/10 Excellent! (1,487 reviews)
"Only bad thing was the parking it was to narrow for my truck . But it all worked out."

Reviewed on Jul 9, 2026

Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$81 nightly
The price is $93 total per night from Aug 9 to Aug 10
$93 total
Aug 9 - Aug 10
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.6/10 (2,133 reviews)
"The room was fine & the person who checked us in. However we checked in at 5 pm & the rooms were not ready."

Reviewed on Jul 10, 2026

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$149 nightly
The price is $171 total per night from Jul 14 to Jul 15
$171 total
Jul 14 - Jul 15
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,752 reviews)
"Family trip traveled with younger kids. Pool was the highlight of their stay along with the Waffle spot (on site restaurant). We stayed upstairs with a pool view. Majority of people staying there were families with small kids, mornings are a bit louder with kids running down the hall. The rooms were ..."

Reviewed on Jul 10, 2026

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$279 nightly
The price is $321 total per night from Aug 9 to Aug 10
$321 total
Aug 9 - Aug 10
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,238 reviews)
"Overall, this is a wonderful place to stay. I'm giving it 4 stars instead of 5 only because housekeeping forgot to replenish the shampoo and body wash when they serviced the room. Aside from that oversight, everything was great."

Reviewed on Jul 10, 2026

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$284 nightly
The price is $326 total per night from Aug 9 to Aug 10
$326 total
Aug 9 - Aug 10
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,417 reviews)
"This is our second trip in which we have stayed at The Dana! We really enjoy it! Great restaurant with firepit tables, food is wonderful. Location is perfect to the beach and access to the freeway. We have booked the jr suite with a bay view, and this past trip was the marina view. We will definately ..."

Reviewed on Jul 10, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$309 nightly
The price is $356 total per night from Aug 9 to Aug 10
$356 total
Aug 9 - Aug 10
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,306 reviews)

Families like: Outdoor pool, game room, on the beach, bicycle rentals

Travelers say...
"The Catamaran is the perfect location for families or couples looking to getaway. The lobby feels like you are in Hawaii and the bay is beautiful. We rented a Hobie Cat sailboat (right from the property) one afternoon and sailed the bay. We were able to park the car and walk to tons of restaurants ..."

Reviewed on Jul 10, 2026

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MDT to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MDT Address & GPS
Address:
One Terminal Drive
Middletown PA, 17057
United States
IATA Code:
MDT
Longitude:
-76.756057
Latitude:
40.196008
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Harrisburg Intl. Airport to San Diego Intl. Airport (SAN)?
Flying from MDT to San Diego Airport means you're going to have to switch planes. But hey — that's OK. American Airlines, Delta Air Lines and United Airlines offer flights with a single stopover.
What is the shortest flight from Harrisburg Intl. Airport (MDT) to San Diego Airport?
Use the opportunity to sit back and chill out on your way from Harrisburg to San Diego. The quickest flight time from Harrisburg Intl. Airport to SAN is 7 hours and 5 minutes, which gives you loads of time to enjoy a wine or lose yourself in a good book.
How many hours flight from Harrisburg Intl. Airport to San Diego Intl. Airport (SAN)?
It usually takes around 7 hours and 9 minutes to fly from Harrisburg Intl. Airport (MDT) to San Diego Airport. You'll be airborne for a good amount of time, so take your own entertainment, like a good read or a podcast.
What airlines have the most flights from MDT to San Diego Intl. Airport (SAN)?
Right now, you can't fly nonstop from Harrisburg to San Diego. However, you will be able to book a flight with one or more stops. It's not all bad — use the break to stretch your legs or go in search of a nice meal!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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