$95 Cheap flight deals from Des Moines (DSM) to Phoenix (PHX)

This Weekend's Flight Deals from Des Moines to Phoenix

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jun 20 - Tue, Jun 24
DSM
Des Moines Intl.
PHX
Sky Harbor Intl.
$373 Roundtrip, found 1 day ago
$373
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Jun 20 from Des Moines Intl. to Sky Harbor Intl., returning Tue, Jun 24, priced at $373 found 1 day ago

Airfares from $95 One Way, $207 Round Trip from Des Moines to Phoenix

Prices starting at $207 for return flights and $95 for one-way flights to Phoenix were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Jul 16 - Mon, Aug 11
DSM
Des Moines
PHX
Phoenix
$207 Roundtrip, found 8 hours ago
$207
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Jul 16 from Des Moines to Phoenix, returning Mon, Aug 11, priced at $207 found 8 hours ago
Fri, Jul 4 - Mon, Jul 7
DSM
Des Moines
PHX
Phoenix
$210 Roundtrip, found 21 hours ago
$210
Roundtrip
found 21 hours ago
Select Frontier Airlines flight, departing Fri, Jul 4 from Des Moines to Phoenix, returning Mon, Jul 7, priced at $210 found 21 hours ago
Fri, Jul 11 - Mon, Jul 14
DSM
Des Moines
PHX
Phoenix
$214 Roundtrip, found 1 day ago
$214
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Jul 11 from Des Moines to Phoenix, returning Mon, Jul 14, priced at $214 found 1 day ago
Wed, Jul 16 - Mon, Aug 11
DSM
Des Moines
PHX
Phoenix
$216 Roundtrip, found 8 hours ago
$216
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Jul 16 from Des Moines to Phoenix, returning Mon, Aug 11, priced at $216 found 8 hours ago
Tue, Jul 8 - Fri, Jul 11
DSM
Des Moines
PHX
Phoenix
$218 Roundtrip, found 13 hours ago
$218
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, Jul 8 from Des Moines to Phoenix, returning Fri, Jul 11, priced at $218 found 13 hours ago

Phoenix economy flight packages

Price found within the past 48 hours. Click for updated prices.
Fairfield Inn & Suites Phoenix Chandler / Fashion Center
3.0-star property

Fairfield Inn & Suites Phoenix Chandler / Fashion Center

8.8/10 Excellent! (1,002 reviews)

Aug 6 - Aug 10

4 night stay

Des Moines (DSM) to Phoenix (PHX)

American Airlines • Roundtrip • Coach
per person
found 1 day ago
Wide open spaces! From the parking lot to the room with a king size bed I had reserved… and got! Clean facility, clean room, and quiet, a well working AC unit (it was 100 hot), this room did not disappoint. Easy check in, a friendly staff, and a delicious breakfast, all led a pleasant stay here. I highly recommend a stay here! And ‘oh yeah, there’s a mall and tons of places to eat, just down the road too!

Reviewed on Jun 21, 2023

Residence Inn by Marriott Phoenix West/Avondale
3.0-star property

Residence Inn by Marriott Phoenix West/Avondale

9.4/10 Exceptional! (549 reviews)

Aug 6 - Aug 10

4 night stay

Des Moines (DSM) to Phoenix (PHX)

American Airlines • Roundtrip • Coach
per person
found 1 day ago
Very clean & nice, a lot of amenities. Breakfast was fresh & good.

Reviewed on May 16, 2025

Residence Inn by Marriott Phoenix Desert View at Mayo Clinic
3.0-star property

Residence Inn by Marriott Phoenix Desert View at Mayo Clinic

8.8/10 Excellent! (789 reviews)

Aug 6 - Aug 10

4 night stay

Des Moines (DSM) to Phoenix (PHX)

American Airlines • Roundtrip • Coach
per person
found 1 day ago
close to the hospital

Reviewed on Mar 24, 2025

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More About Flying To Phoenix from Des Moines

Route Information for Flights from Des Moines to Phoenix

Origin Airport IATA Code
DSM
Destination Airport IATA Code
PHX
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Frequently asked questions

Are there non-stop flights from Des Moines to Phoenix?
Yes, American Airlines flies direct from Des Moines to Phoenix, so you’ll be touching down and starting your awesome adventure in no time at all.
What is the shortest flight from Des Moines to Phoenix?
The shortest flight time from DSM to PHX is 3 hours and 40 minutes, which gives you plenty of time to enjoy a wine or get engrossed in a book.
What airlines fly from Des Moines to Phoenix most frequently?
Organize your Des Moines to Phoenix trip with an American Airlines flight. With 60 every month, this airline has the most flights along this route.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.