$114 Cheap flight deals from St. Louis (STL) to Key West (EYW)

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This Weekend's Flight Deals from St. Louis to Key West

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, May 18 - Thu, May 29
STL
Lambert-St. Louis Intl.
EYW
Key West Intl.
$345 Roundtrip, found 2 days ago
$345
Roundtrip
found 2 days ago
Select Delta flight, departing Sun, May 18 from Lambert-St. Louis Intl. to Key West Intl., returning Thu, May 29, priced at $345 found 2 days ago

Airfares from $114 One Way, $223 Round Trip from St. Louis to Key West

Prices starting at $223 for return flights and $114 for one-way flights to Key West were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Sep 9 - Wed, Sep 24
STL
St. Louis
EYW
Key West
$223 Roundtrip, found 1 day ago
$223
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Sep 9 from St. Louis to Key West, returning Wed, Sep 24, priced at $223 found 1 day ago
Tue, Oct 28 - Tue, Nov 4
STL
St. Louis
EYW
Key West
$226 Roundtrip, found 3 days ago
$226
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Oct 28 from St. Louis to Key West, returning Tue, Nov 4, priced at $226 found 3 days ago
Tue, Sep 9 - Fri, Sep 26
STL
St. Louis
EYW
Key West
$241 Roundtrip, found 1 day ago
$241
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Sep 9 from St. Louis to Key West, returning Fri, Sep 26, priced at $241 found 1 day ago
Mon, Aug 25 - Sat, Aug 30
STL
St. Louis
EYW
Key West
$241 Roundtrip, found 5 hours ago
$241
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Mon, Aug 25 from St. Louis to Key West, returning Sat, Aug 30, priced at $241 found 5 hours ago
Tue, Aug 12 - Wed, Aug 27
STL
St. Louis
EYW
Key West
$243 Roundtrip, found 6 days ago
$243
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Aug 12 from St. Louis to Key West, returning Wed, Aug 27, priced at $243 found 6 days ago

More About Flying To Key West from St. Louis

Route Information for Flights from St. Louis to Key West

Origin Airport IATA Code
STL
Destination Airport IATA Code
EYW
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

St. Louis to Key West

With discount prices on flights from St. Louis to Key West and cutting-edge mobile tools, Orbitz is the best partner when you want to book your travel plans online.

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Orbitz is dedicated to helping you find the best travel deals on the market for flights from St. Louis to Key West. Our low price guarantee means you get fares that keep more money in your wallet. Pick and choose the dates, times, and airlines for your St. Louis flights to Key West to find the flight that is right for you.

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Frequently asked questions

Am I able to catch a flight from St. Louis to Key West now?
Our Covid-19 Travel Advisor can answer all your questions about current quarantine requirements and travel restrictions when taking a flight from St. Louis to Key West.
What is the shortest flight from St. Louis to Key West?
From St. Louis, the distinctive sights and sounds of Key West are at least 3 hours and 16 minutes away. Book your favorite seat, or perhaps even upgrade to one with extra legroom, and get to your destination in comfort.
If I am not able to travel due to COVID-19, can I cancel my flight to Key West?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Key West have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Key West with flexible change policies?
In most cases you’ll have the option to reschedule your flight to Key West without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2020 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data the cheapest month to fly is August. Perfect for those who need a weekend getaway, or just a break from it all before the weather changes. Be aware that the most expensive time to fly is the height of summer, with ticket prices peaking in the month of June.
How can I save money on flights?
To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you’ll generally get a much better deal. Those who tried this on Orbitz in 2020 saved up to 45% on their airfares. Get mixing and matching today!

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.