Cheap flights from TYS to HOU (McGhee Tyson to William P. Hobby)

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Cheap Flights from TYS to HOU starting at $151 One Way, $289 Round Trip

Prices starting at $289 for return flights and $151 for one-way flights to William P. Hobby were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Sep 19 - Sun, Sep 20
TYS
Knoxville
HOU
Houston
$289 Roundtrip, found 9 hours ago
$289
Roundtrip
found 9 hours ago
Select Delta flight, departing Sat, Sep 19 from Knoxville to Houston, returning Sun, Sep 20, priced at $289 found 9 hours ago
Thu, Jul 23 - Mon, Jul 27
TYS
Knoxville
HOU
Houston
$294 Roundtrip, found 3 days ago
$294
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Jul 23 from Knoxville to Houston, returning Mon, Jul 27, priced at $294 found 3 days ago
Thu, Jul 23 - Mon, Jul 27
TYS
Knoxville
HOU
Houston
$329 Roundtrip, found 3 days ago
$329
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Thu, Jul 23 from Knoxville to Houston, returning Mon, Jul 27, priced at $329 found 3 days ago

Hotel Ideas near William P. Hobby

Airport Hotels near William P. Hobby

Best Western Plus Hobby Airport Inn & Suites

Best Western Plus Hobby Airport Inn & Suites

2.5 out of 5
8778 Airport Blvd Houston TX
$81 nightly
The price is $95 total per night from Jun 3 to Jun 4
$95 total
Jun 3 - Jun 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,558 reviews)
"Check in was fine. Purposely chose this hotel as there is a shuttle to the airport. While attempting to check out to let staff know I would need the shuttle, front desk staff placed a sign that they were unavailable while I was second in line. Please note the guests in front of me told front desk ..."

Reviewed on May 26, 2026

Best Western Plus Hobby Airport Inn & Suites
Houston Marriott South at Hobby Airport

Houston Marriott South at Hobby Airport

3.5 out of 5
9100 Gulf Fwy Houston TX
$95 nightly
The price is $111 total per night from May 29 to May 30
$111 total
May 29 - May 30
Total with taxes and fees
Book a stay at this family-friendly hotel in Houston. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,476 reviews)
"We have stayed here several times, and it was very nice, but this time manger was rude and for some reason there was a lot of drug uses this time where there was a lot of kids present very unprofessional"

Reviewed on May 25, 2026

Houston Marriott South at Hobby Airport
Palace Inn Blue Edgebrook

Palace Inn Blue Edgebrook

3 out of 5
10224 Gulf Freeway Houston TX
$104 nightly
The price is $122 total per night from May 28 to May 29
$122 total
May 28 - May 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Almeda Mall and Gulfgate Shopping ...
9.4/10 Exceptional! (174 reviews)
"Very clean."

Reviewed on May 26, 2026

Palace Inn Blue Edgebrook
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Houston

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
$135 nightly
The price is $158 total per night from Jun 6 to Jun 7
$158 total
Jun 6 - Jun 7
Total with taxes and fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (4,079 reviews)
"The staff was excellent and perfectly attentive to any and all needs. The property is not kept up well though. The hinges on doors in the bathroom are rusted. The toilet is sized for a toddler. The amenities are very outdated. You can’t even stream on the tv’s. The towels are not adult size."

Reviewed on May 26, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
$246 nightly
The price is $288 total per night from May 28 to May 29
$288 total
May 28 - May 29
Total with taxes and fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,001 reviews)
"Great hotel and great location"

Reviewed on May 27, 2026

Hotel Zaza Houston Museum District
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
$110 nightly
The price is $128 total per night from May 31 to Jun 1
$128 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (4,187 reviews)
"I loved my week long stay at Club Quarters in downtown Houston. Sadly the awesome coffee machine in the lobby was broken for 6 of the days of my stay. The lobby was lovely and inviting. My room had a little kitchenette and was very comfortable. The location was great and the in house restaurant was ..."

Reviewed on May 27, 2026

Club Quarters Hotel Downtown, Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Houston Hotels With Airport Transportation

Ramada by Wyndham Houston Intercontinental Airport East

Ramada by Wyndham Houston Intercontinental Airport East

3.5 out of 5
6115 Will Clayton Parkway Humble TX
$67 nightly
The price is $78 total per night from May 28 to May 29
$78 total
May 28 - May 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Humble. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the restaurant and the helpful staff ...
7.6/10 Good! (2,153 reviews)
"Very helpful & friendly staff. Shuttle service to the airport was super convenient"

Reviewed on May 27, 2026

Ramada by Wyndham Houston Intercontinental Airport East
La Quinta Inn & Suites by Wyndham Houston Bush Intl Airpt E

La Quinta Inn & Suites by Wyndham Houston Bush Intl Airpt E

3 out of 5
18201 Kenswick Drive Humble TX
$77 nightly
The price is $90 total per night from May 30 to May 31
$90 total
May 30 - May 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Humble. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the clean rooms in our ...
7.8/10 Good! (2,415 reviews)
"Clean"

Reviewed on May 26, 2026

La Quinta Inn & Suites by Wyndham Houston Bush Intl Airpt E
Days Inn by Wyndham Humble/Houston Intercontinental Airport

Days Inn by Wyndham Humble/Houston Intercontinental Airport

2.5 out of 5
9824 J M Hester Road Humble TX
$58 nightly
The price is $68 total per night from May 28 to May 29
$68 total
May 28 - May 29
Total with taxes and fees
Book a stay at this business-friendly motel in Humble. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the helpful staff and the ...
7.2/10 Good! (1,002 reviews)
"You pay for what you get. It’s nothing fancy, but it was clean enough to stay for a night. The blanket was basically a sheet it was so thin. I will stay somewhere else maybe a bit more expensive if I need to come again."

Reviewed on May 26, 2026

Days Inn by Wyndham Humble/Houston Intercontinental Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Houston Hotels

Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
$110 nightly
The price is $128 total per night from May 31 to Jun 1
$128 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (4,187 reviews)
"I loved my week long stay at Club Quarters in downtown Houston. Sadly the awesome coffee machine in the lobby was broken for 6 of the days of my stay. The lobby was lovely and inviting. My room had a little kitchenette and was very comfortable. The location was great and the in house restaurant was ..."

Reviewed on May 27, 2026

Club Quarters Hotel Downtown, Houston
Ramada by Wyndham Houston Intercontinental Airport East

Ramada by Wyndham Houston Intercontinental Airport East

3.5 out of 5
6115 Will Clayton Parkway Humble TX
$67 nightly
The price is $78 total per night from May 28 to May 29
$78 total
May 28 - May 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Humble. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the restaurant and the helpful staff ...
7.6/10 Good! (2,153 reviews)
"Very helpful & friendly staff. Shuttle service to the airport was super convenient"

Reviewed on May 27, 2026

Ramada by Wyndham Houston Intercontinental Airport East
GreenTree Inn Houston IAH Airport

GreenTree Inn Houston IAH Airport

2 out of 5
15675 John F. Kennedy Blvd Houston TX
$49 nightly
The price is $57 total per night from May 29 to May 30
$57 total
May 29 - May 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,158 reviews)
"AirPort shuttle"

Reviewed on May 25, 2026

GreenTree Inn Houston IAH Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Houston

SpringHill Suites Houston Medical Center/NRG Park

SpringHill Suites Houston Medical Center/NRG Park

3 out of 5
1400 Old Spanish Trl Houston TX
$122 nightly
The price is $143 total per night from Jun 7 to Jun 8
$143 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,001 reviews)
"Awesome staff."

Reviewed on May 18, 2026

SpringHill Suites Houston Medical Center/NRG Park
The Woodlands Resort, Curio Collection by Hilton

The Woodlands Resort, Curio Collection by Hilton

4 out of 5
2301 North Millbend Drive The Woodlands TX
$220 nightly
The price is $253 total per night from May 31 to Jun 1
$253 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this golf resort in The Woodlands. Enjoy free WiFi, 2 outdoor pools, and 4 restaurants. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,000 reviews)

Families like: Outdoor pools, waterslide, game room, bicycle rentals

Travelers say...
"Take mor money at checkout"

Reviewed on May 27, 2026

The Woodlands Resort, Curio Collection by Hilton
SpringHill Suites by Marriott Houston NASA/Webster

SpringHill Suites by Marriott Houston NASA/Webster

3 out of 5
1101 Magnolia Street Webster TX
$107 nightly
The price is $125 total per night from Jun 4 to Jun 5
$125 total
Jun 4 - Jun 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Webster. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,000 reviews)
"Breakfast was good"

Reviewed on May 26, 2026

SpringHill Suites by Marriott Houston NASA/Webster
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

TYS to HOU Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York
HOU Address & GPS
Address:
7800 Airport Boulevard
Houston TX, 77061
United States
IATA Code:
HOU
Longitude:
-95.277018
Latitude:
29.654513
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from McGhee Tyson Airport (TYS) to William P. Hobby Airport?
While you can't fly nonstop from Knoxville Airport to William P. Hobby Airport (HOU) at this point in time, there are a number of air carriers that operate on this route with just one stopover. Why not check if the dates and times available with Delta Air Lines or American Airlines match your travel plans? If not, check out Frontier Airlines.
What is the shortest flight from Knoxville Airport to William P. Hobby Airport (HOU)?
The shortest flight from TYS to William P. Hobby Airport (HOU) is 4 hours and 20 minutes. Bring something on board to keep you occupied, like the latest edition of your favorite magazine or a sketch pad.
How many hours flight from Knoxville Airport to William P. Hobby Airport?
Settle in and get comfy, because the average flight time from TYS to William P. Hobby Airport is 4 hours and 29 minutes. Watch a movie or two, get stuck into that book ... You'll have ample time to sit back and relax.
What airlines have the most flights from Knoxville Airport to William P. Hobby Airport (HOU)?
Do a bit of shopping, tuck into some takeaway, chat with a stranger ... Airport stopovers don't have to be something to dread! If you're jetting from TYS to HOU, you can't fly direct. Be prepared to make at least one stop somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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