Cheap flights from TYS to EYW (McGhee Tyson to Key West Intl.)
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Cheap Flights from TYS to EYW starting at $42 One Way, $96 Round Trip
Prices starting at $96 for return flights and $42 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
TYS
Knoxville
EYW
Key West
$96 Roundtrip, found 17 hours ago
$96
Roundtrip
found 17 hours ago
TYS
Knoxville
EYW
Key West
$97 Roundtrip, found 5 days ago
$97
Roundtrip
found 5 days ago
TYS
Knoxville
EYW
Key West
$100 Roundtrip, found 5 days ago
$100
Roundtrip
found 5 days ago
TYS
Knoxville
EYW
Key West
$101 Roundtrip, found 1 hour ago
$101
Roundtrip
found 1 hour ago
TYS
Knoxville
EYW
Key West
$105 Roundtrip, found 2 hours ago
$105
Roundtrip
found 2 hours ago
Hotel Ideas near Key West Intl.
Airport Hotels near Key West Intl.
Hyatt Vacation Club at Windward Pointe, Key West
3675 South Roosevelt Boulevard Key West FL
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,299 reviews)
"I loved the outdoor area and pool! We utilized the grill area as we had a big party and it was great!! I would have game 5 stars for everything but I was not advised during check in that cleaning staff do not come in daily. I had to call every day for towels (they were delivered quickly) but the ..."
Reviewed on Sep 28, 2026
Hampton Inn Key West FL
3755 S Roosevelt Blvd Key West FL
$166 nightly
The price is $186 total per night from Oct 6 to Oct 7
$186 total
Oct 6 - Oct 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,532 reviews)
"Staff was great, shuttles were timely and helpful, rooms were clean, pool was nice."
Reviewed on Sep 28, 2026
DoubleTree Resort by Hilton Grand Key - Key West
3990 S Roosevelt Blvd Key West FL
$159 nightly
The price is $179 total per night from Sep 29 to Sep 30
$179 total
Sep 29 - Sep 30
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,110 reviews)
"Close to everything, comfortable stay"
Reviewed on Sep 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Key West
Blue Flamingo Resort Key West
3820 North Roosevelt Boulevard Key West FL
$168 nightly
The price is $189 total per night from Sep 29 to Sep 30
$189 total
Sep 29 - Sep 30
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,698 reviews)
"The grounds are beautiful. One morning I watched them pressure wash around the pool area and they cleaned everything. There was so much to take in and since the grounds are beautiful so many places for photos. The room we stayed in was clean and even though we faced the busy street the noice was ..."
Reviewed on Sep 28, 2026
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
$229 nightly
The price is $258 total per night from Sep 29 to Sep 30
$258 total
Sep 29 - Sep 30
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (3,636 reviews)
"A+"
Reviewed on Sep 28, 2026
Margaritaville Beach House Key West
2001 South Roosevelt Blvd Key West FL
$265 nightly
The price is $298 total per night from Sep 29 to Sep 30
$298 total
Sep 29 - Sep 30
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the pool and the restaurant ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Key West Hotels With Airport Transportation
DoubleTree Resort by Hilton Grand Key - Key West
3990 S Roosevelt Blvd Key West FL
$159 nightly
The price is $179 total per night from Sep 29 to Sep 30
$179 total
Sep 29 - Sep 30
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,110 reviews)
"Close to everything, comfortable stay"
Reviewed on Sep 28, 2026
Hampton Inn Key West FL
3755 S Roosevelt Blvd Key West FL
$166 nightly
The price is $186 total per night from Oct 6 to Oct 7
$186 total
Oct 6 - Oct 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,532 reviews)
"Staff was great, shuttles were timely and helpful, rooms were clean, pool was nice."
Reviewed on Sep 28, 2026
Eden House
1015 Fleming St Key West FL
$180 nightly
The price is $202 total per night from Sep 30 to Oct 1
$202 total
Sep 30 - Oct 1
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Key West Hotels
Southwinds Motel
1321 Simonton Street Key West FL
$155 nightly
The price is $174 total per night from Sep 29 to Sep 30
$174 total
Sep 29 - Sep 30
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,389 reviews)
"Wonderful"
Reviewed on Sep 27, 2026
Seashell Motel
718 South Street Key West FL
$101 nightly
The price is $114 total per night from Sep 29 to Sep 30
$114 total
Sep 29 - Sep 30
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,003 reviews)
"Loved the room and especially the free WiFi and parking!"
Reviewed on Sep 27, 2026
Duval House
815 Duval St Key West FL
$119 nightly
The price is $131 total per night from Oct 5 to Oct 6
$131 total
Oct 5 - Oct 6
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.6/10 Exceptional! (1,105 reviews)
"*"
Reviewed on Sep 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Key West
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
$229 nightly
The price is $258 total per night from Sep 29 to Sep 30
$258 total
Sep 29 - Sep 30
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (3,636 reviews)
"A+"
Reviewed on Sep 28, 2026
Blue Flamingo Resort Key West
3820 North Roosevelt Boulevard Key West FL
$168 nightly
The price is $189 total per night from Sep 29 to Sep 30
$189 total
Sep 29 - Sep 30
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,698 reviews)
Families like: Outdoor pools, playground, miniature golf, game room
Travelers say...
"The grounds are beautiful. One morning I watched them pressure wash around the pool area and they cleaned everything. There was so much to take in and since the grounds are beautiful so many places for photos. The room we stayed in was clean and even though we faced the busy street the noice was ..."
Reviewed on Sep 28, 2026
Hilton Key West Resort & Marina
5950 Peninsular Avenue Key West FL
$180 nightly
The price is $202 total per night from Oct 6 to Oct 7
$202 total
Oct 6 - Oct 7
Total with taxes and fees
Book a stay at this luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
TYS to EYW Route Info
Origin Airport | |
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Destination Airport | |
Number Of Airlines Serving | |
Distance | |
Shortest Flight Departure Time | |
Shortest Flight Departure Date |
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York
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Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.
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